Claudin-1 expression in airway smooth muscle exacerbates airway remodeling in asthmatic subjects

Journal of Allergy and Clinical Immunology

Volumn 127, Issue 6, 2011, Pages

  Fujita, Hiroyuki ^a,b   Chalubinski, MacIej ^a,b   Rhyner, Claudio ^a   Indermitte, Philippe ^a   Meyer, Norbert ^a   Ferstl, Ruth ^a   Treis, Angela ^a   Gomez, Enrique ^a   Akkaya, Ahmet ^c   O'Mahony, Liam ^a   Akdis, Mübeccel ^a   Akdis, Cezmi A ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b CHRISTINE KÜHNE CENTER FOR ALLERGY RESEARCH AND EDUCATION CK CARE   (Switzerland)

^c SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Airway remodeling; airway smooth muscle; asthma; claudin 1; cytokine; IFN induced protein 10; proliferation; tight junction; treatment; vascular endothelial growth factor

Indexed keywords

CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; CLAUDIN 1; DEXAMETHASONE; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 8; MESSENGER RNA; OVALBUMIN; RAPAMYCIN; SALBUTAMOL; SMALL INTERFERING RNA; TACROLIMUS; THYMIDINE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

AIRWAY REMODELING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHUS BIOPSY; CELL NUCLEUS; CELL PROLIFERATION; CELL SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; DISEASE EXACERBATION; DOWN REGULATION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; LUNG ALVEOLUS WALL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEVERE PERSISTENT ASTHMA; SMOOTH MUSCLE FIBER; TH2 CELL; TREATMENT OUTCOME; UPREGULATION; WESTERN BLOTTING; WOUND HEALING;

EID: 79957850572     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.03.039     Document Type: Article

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