Exploring the repertoire of IgE-binding self-antigens associated with atopic eczema

Journal of Allergy and Clinical Immunology

Volumn 124, Issue 2, 2009, Pages

  Zeller, Sabine ^a   Rhyner, Claudio ^a   Meyer, Norbert ^a,b   Schmid Grendelmeier, Peter ^c   Akdis, Cezmi A ^a   Crameri, Reto ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b Hochgebirgsklinik   (Switzerland)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

atopic dermatitis; Atopic eczema; autoreactivity; IgE; mediator release; self antigens

Indexed keywords

ACTIN; ALLERGEN; ANTIBODY; ANTIGEN; CALMODULIN; COMPLEMENTARY DNA; EUKARYOTIC TRANSLATIONAL INITIATION FACTOR 6; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; INITIATION FACTOR; MANGANESE SUPEROXIDE DISMUTASE; MYOSIN; MYOSIN 1C; PROFILIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; RECOMBINANT ANTIGEN; RIBOSOME PROTEIN; UNCLASSIFIED DRUG;

ADULT; AMINO ACID SEQUENCE; ANTIBODY PRODUCTION; ANTIGEN BINDING; ARTICLE; ATOPIC DERMATITIS; BASOPHIL; CLONE; CONTROLLED STUDY; DNA LIBRARY; ENZYME LINKED IMMUNOSORBENT ASSAY; EVOLUTIONARY HOMOLOGY; EXPERIMENTATION; FEMALE; GENOME; HIGH THROUGHPUT SCREENING; HUMAN; IMMUNOBLOTTING; IMMUNOGLOBULIN BLOOD LEVEL; LYMPHOCYTE ACTIVATION; MAJOR CLINICAL STUDY; MALE; MEDIATOR RELEASE; MOLECULAR CLONING; PRIORITY JOURNAL; SCREENING; SENSITIZATION; SERUM; SKIN INFLAMMATION; WESTERN BLOTTING;

EID: 67849101642     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2009.05.015     Document Type: Article

References (40)

1. Hampton S., and Cooke R. The sensitivity of man to human dander, with particular reference to eczema (allergic dermatitis). J Allergy 13 (1941) 63-76
2. Simon F. On the allergen in human dander. J Allergy 15 (1944) 338-345
3. Crameri R., Jaussi R., Menz G., and Blaser K. Display of expression products of cDNA libraries on phage surfaces. A versatile screening system for selective isolation of genes by specific gene-product/ligand interaction. Eur J Biochem 226 (1994) 53-58
4. Harbers M. The current status of cDNA cloning. Genomics 91 (2008) 232-242
5. Dingermann T. Recombinant therapeutic proteins: production platforms and challenges. Biotechnol J 3 (2008) 90-97
6. Natter S., Seiberler S., Hufnagl P., Binder B.R., Hirschl A.M., Ring J., et al. Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients. FASEB J 12 (1998) 1559-1569
7. Appenzeller U., Meyer C., Menz G., Blaser K., and Crameri R. IgE-mediated reactions to autoantigens in allergic diseases. Int Arch Allergy Immunol 118 (1999) 193-196
8. Akdis C.A., Akdis M., Bieber T., Bindslev-Jensen C., Boguniewicz M., Eigenmann P., et al. Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. Allergy 61 (2006) 969-987
9. O'Regan G.M., Sandilands A., McLean W.H., and Irvine A.D. Filaggrin in atopic dermatitis. J Allergy Clin Immunol 122 (2008) 689-693
10. Vercelli D. Genetics, epigenetics, and the environment: switching, buffering, releasing. J Allergy Clin Immunol 113 (2004) 381-386
11. Valenta R., Seiberler S., Natter S., Mahler V., Mossabeb R., Ring J., et al. Autoallergy: a pathogenetic factor in atopic dermatitis?. J Allergy Clin Immunol 105 (2000) 432-437
12. Zeller S., Glaser A.G., Vilhelmsson M., Rhyner C., and Crameri R. Immunoglobulin-E-mediated reactivity to self antigens: a controversial issue. Int Arch Allergy Immunol 145 (2008) 87-93
13. Crameri R., Faith A., Hemmann S., Jaussi R., Ismail C., Menz G., et al. Humoral and cell-mediated autoimmunity in allergy to Aspergillus fumigatus. J Exp Med 184 (1996) 265-270
14. Fluckiger S., Mittl P.R., Scapozza L., Fijten H., Folkers G., Grutter M.G., et al. Comparison of the crystal structures of the human manganese superoxide dismutase and the homologous Aspergillus fumigatus allergen at 2-A resolution. J Immunol 168 (2002) 1267-1272
15. Mayer C., Appenzeller U., Seelbach H., Achatz G., Oberkofler H., Breitenbach M., et al. Humoral and cell-mediated autoimmune reactions to human acidic ribosomal P2 protein in individuals sensitized to Aspergillus fumigatus P2 protein. J Exp Med 189 (1999) 1507-1512
16. Fluckiger S., Fijten H., Whitley P., Blaser K., and Crameri R. Cyclophilins, a new family of cross-reactive allergens. Eur J Immunol 32 (2002) 10-17
17. Glaser A.G., Limacher A., Fluckiger S., Scheynius A., Scapozza L., and Crameri R. Analysis of the cross-reactivity and of the 1.5 A crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family. Biochem J 396 (2006) 41-49
18. Weichel M., Glaser A.G., Ballmer-Weber B.K., Schmid-Grendelmeier P., and Crameri R. Wheat and maize thioredoxins: a novel cross-reactive cereal allergen family related to baker's asthma. J Allergy Clin Immunol 117 (2006) 676-681
19. Limacher A., Glaser A.G., Meier C., Schmid-Grendelmeier P., Zeller S., Scapozza L., et al. Cross-reactivity and 1.4-A crystal structure of Malassezia sympodialis thioredoxin (Mala s 13), a member of a new pan-allergen family. J Immunol 178 (2007) 389-396
20. Schmid-Grendelmeier P., Fluckiger S., Disch R., Trautmann A., Wuthrich B., Blaser K., et al. IgE-mediated and T cell-mediated autoimmunity against manganese superoxide dismutase in atopic dermatitis. J Allergy Clin Immunol 115 (2005) 1068-1075
21. Valenta R., Natter S., Seiberler S., Wichlas S., Maurer D., Hess M., et al. Molecular characterization of an autoallergen, Hom s 1, identified by serum IgE from atopic dermatitis patients. J Invest Dermatol 111 (1998) 1178-1183
22. Mittermann I., Reininger R., Zimmermann M., Gangl K., Reisinger J., Aichberger K.J., et al. The IgE-reactive autoantigen Hom s 2 induces damage of respiratory epithelial cells and keratinocytes via induction of IFN-gamma. J Invest Dermatol 128 (2008) 1451-1459
23. Kodzius R., Rhyner C., Konthur Z., Buczek D., Lehrach H., Walter G., et al. Rapid identification of allergen-encoding cDNA clones by phage display and high-density arrays. Comb Chem High Throughput Screen 6 (2003) 147-154
24. Rhyner C., Weichel M., Fluckiger S., Hemmann S., Kleber-Janke T., and Crameri R. Cloning allergens via phage display. Methods 32 (2004) 212-218
25. Maier E., Meier-Ewert S., Ahmadi A.R., Curtis J., and Lehrach H. Application of robotic technology to automated sequence fingerprint analysis by oligonucleotide hybridisation. J Biotechnol 35 (1994) 191-203
26. Pearson W.R. Searching protein sequence libraries: comparison of the sensitivity and selectivity of the Smith-Waterman and FASTA algorithms. Genomics 11 (1991) 635-650
27. Crowe J., Dobeli H., Gentz R., Hochuli E., Stuber D., and Henco K. 6xHis-Ni-NTA chromatography as a superior technique in recombinant protein expression/purification. Methods Mol Biol 31 (1994) 371-387
28. Moser M., Crameri R., Brust E., Suter M., and Menz G. Diagnostic value of recombinant Aspergillus fumigatus allergen I/a for skin testing and serology. J Allergy Clin Immunol 93 (1994) 1-11
29. Hemmann S., Ismail C., Blaser K., Menz G., and Crameri R. Skin-test reactivity and isotype-specific immune responses to recombinant Asp f 3, a major allergen of Aspergillus fumigatus. Clin Exp Allergy 28 (1998) 860-867
30. Buhring H.J., Streble A., and Valent P. The basophil-specific ectoenzyme E-NPP3 (CD203c) as a marker for cell activation and allergy diagnosis. Int Arch Allergy Immunol 133 (2004) 317-329
31. Sudheer P.S., Hall J.E., Read G.F., Rowbottom A.W., and Williams P.E. Flow cytometric investigation of peri-anaesthetic anaphylaxis using CD63 and CD203c. Anaesthesia 60 (2005) 251-256
32. Hanifin J., and Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venerol 92 (1980) 44-47
33. Johansson S.G., Bieber T., Dahl R., Friedmann P.S., Lanier B.Q., Lockey R.F., et al. Revised nomenclature for allergy for global use: report of the Nomenclature Review Committee of the World Allergy Organization, October 2003. J Allergy Clin Immunol 113 (2004) 832-836
34. Severity scoring of atopic dermatitis: the SCORAD index. Consensus report of the European Task Force on Atopic Dermatitis. Dermatology 186 (1993) 23-31
35. Valenta R., Duchene M., Pettenburger K., Sillaber C., Valent P., Bettelheim P., et al. Identification of profilin as a novel pollen allergen; IgE autoreactivity in sensitized individuals. Science 253 (1991) 557-560
36. Wopfner N., Dissertori O., Ferreira F., and Lackner P. Calcium-binding proteins and their role in allergic diseases. Immunol Allergy Clin North Am 27 (2007) 29-44
37. Witteman A.M., Akkerdaas J.H., van Leeuwen J., van der Zee J.S., and Aalberse R.C. Identification of a cross-reactive allergen (presumably tropomyosin) in shrimp, mite and insects. Int Arch Allergy Immunol 105 (1994) 56-61
38. Ichikawa S., Hatanaka H., Yuuki T., Iwamoto N., Kojima S., Nishiyama C., et al. Solution structure of Der f 2, the major mite allergen for atopic diseases. J Biol Chem 273 (1998) 356-360
39. Altrichter S., Kriehuber E., Moser J., Valenta R., Kopp T., and Stingl G. Serum IgE autoantibodies target keratinocytes in patients with atopic dermatitis. J Invest Dermatol 128 (2008) 2232-2239
40. Sehra S., Tuana F.M., Holbreich M., Mousdicas N., Tepper R.S., Chang C.H., et al. Scratching the surface: towards understanding the pathogenesis of atopic dermatitis. Crit Rev Immunol 28 (2008) 15-43