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Volumn 133, Issue 3, 2011, Pages 318-328

The reconstitution of the thymus in immunosuppressed individuals restores CD4-specific cellular and humoral immune responses

Author keywords

Adjuvant; Cellular responses; Growth hormone; HIV; Humoral responses; Thymus

Indexed keywords

CD4 ANTIGEN; CD45RA ANTIGEN; CD45RO ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR5; DITANRIX ADULTOS; GAG PROTEIN; HEPATITIS A HEPATITIS B VACCINE; INTERLEUKIN 2 RECEPTOR ALPHA; PADGEM PROTEIN; RECOMBINANT GROWTH HORMONE; SOMATREM; TETANUS TOXOID; TWINRIX ADULTOS; UNCLASSIFIED DRUG;

EID: 79957834507     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2011.03442.x     Document Type: Article
Times cited : (15)

References (33)
  • 1
    • 3242773778 scopus 로고    scopus 로고
    • + T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation
    • + T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation. Blood 2004; 104:775-80.
    • (2004) Blood , vol.104 , pp. 775-780
    • Sereti, I.1    Anthony, K.B.2    Martinez-Wilson, H.3
  • 2
    • 0035964691 scopus 로고    scopus 로고
    • Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function
    • Teixeira L, Valdez H, McCune JM et al. Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function. Aids 2001; 15:1749-56.
    • (2001) Aids , vol.15 , pp. 1749-1756
    • Teixeira, L.1    Valdez, H.2    McCune, J.M.3
  • 3
    • 0036433692 scopus 로고    scopus 로고
    • The contribution of the thymus to immune reconstitution after hematopoietic stem-cell transplantation
    • Douek DC. The contribution of the thymus to immune reconstitution after hematopoietic stem-cell transplantation. Cytotherapy 2002; 4:425-6.
    • (2002) Cytotherapy , vol.4 , pp. 425-426
    • Douek, D.C.1
  • 5
    • 66249095342 scopus 로고    scopus 로고
    • Impact of growth hormone (GH) deficiency and GH replacement upon thymus function in adult patients
    • Morrhaye G, Kermani H, Legros JJ et al. Impact of growth hormone (GH) deficiency and GH replacement upon thymus function in adult patients. PLoS ONE 2009; 4:e5668.
    • (2009) PLoS ONE , vol.4
    • Morrhaye, G.1    Kermani, H.2    Legros, J.J.3
  • 7
    • 0037165910 scopus 로고    scopus 로고
    • Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone
    • Napolitano LA, Lo JC, Gotway MB et al. Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone. Aids 2002; 16:1103-11.
    • (2002) Aids , vol.16 , pp. 1103-1111
    • Napolitano, L.A.1    Lo, J.C.2    Gotway, M.B.3
  • 8
    • 0036801553 scopus 로고    scopus 로고
    • Immune recovery in HIV disease: role of the thymus and T cell expansion in immune reconstitution strategies
    • Al-Harthi L, Landay A. Immune recovery in HIV disease: role of the thymus and T cell expansion in immune reconstitution strategies. J Hematother Stem Cell Res 2002; 11:777-86.
    • (2002) J Hematother Stem Cell Res , vol.11 , pp. 777-786
    • Al-Harthi, L.1    Landay, A.2
  • 9
    • 1542349076 scopus 로고    scopus 로고
    • Enhanced T-cell maturation, differentiation and function in HIV-1-infected individuals after growth hormone and highly active antiretroviral therapy
    • Pires A, Pido-Lopez J, Moyle G, Gazzard B, Gotch F, Imami N. Enhanced T-cell maturation, differentiation and function in HIV-1-infected individuals after growth hormone and highly active antiretroviral therapy. Antivir Ther 2004; 9:67-75.
    • (2004) Antivir Ther , vol.9 , pp. 67-75
    • Pires, A.1    Pido-Lopez, J.2    Moyle, G.3    Gazzard, B.4    Gotch, F.5    Imami, N.6
  • 10
    • 58149396120 scopus 로고    scopus 로고
    • Effects of recombinant human growth hormone on HIV-1-specific T-cell responses, thymic output and proviral DNA in patients on HAART: 48-week follow-up
    • Herasimtschuk AA, Westrop SJ, Moyle GJ, Downey JS, Imami N. Effects of recombinant human growth hormone on HIV-1-specific T-cell responses, thymic output and proviral DNA in patients on HAART: 48-week follow-up. J Immune Based Ther Vaccines 2008; 6:7.
    • (2008) J Immune Based Ther Vaccines , vol.6 , pp. 7
    • Herasimtschuk, A.A.1    Westrop, S.J.2    Moyle, G.J.3    Downey, J.S.4    Imami, N.5
  • 11
    • 40549089870 scopus 로고    scopus 로고
    • Growth hormone enhances thymic function in HIV-1-infected adults
    • Napolitano LA, Schmidt D, Gotway MB et al. Growth hormone enhances thymic function in HIV-1-infected adults. J Clin Invest 2008; 118:1085-98.
    • (2008) J Clin Invest , vol.118 , pp. 1085-1098
    • Napolitano, L.A.1    Schmidt, D.2    Gotway, M.B.3
  • 13
    • 0037093057 scopus 로고    scopus 로고
    • T-cell repopulation and thymic volume in HIV-1-infected adult patients after highly active antiretroviral therapy
    • Franco JM, Rubio A, Martinez-Moya M, Leal M, Merchante E, Sanchez-Quijano A, Lissen E. T-cell repopulation and thymic volume in HIV-1-infected adult patients after highly active antiretroviral therapy. Blood 2002; 99:3702-6.
    • (2002) Blood , vol.99 , pp. 3702-3706
    • Franco, J.M.1    Rubio, A.2    Martinez-Moya, M.3    Leal, M.4    Merchante, E.5    Sanchez-Quijano, A.6    Lissen, E.7
  • 14
    • 78249271071 scopus 로고    scopus 로고
    • Distribution of CD31 on CD4 T cells from cord blood, peripheral blood and tonsil at different stages of differentiation
    • Ruiz-Hernandez R, Jou A, Cabrera C et al. Distribution of CD31 on CD4 T cells from cord blood, peripheral blood and tonsil at different stages of differentiation. Open Immunol J 2010; 3:19-26.
    • (2010) Open Immunol J , vol.3 , pp. 19-26
    • Ruiz-Hernandez, R.1    Jou, A.2    Cabrera, C.3
  • 15
    • 58849159109 scopus 로고    scopus 로고
    • Antigp41 antibodies fail to block early events of virological synapses but inhibit HIV spread between T cells
    • Massanella M, Puigdomenech I, Cabrera C et al. Antigp41 antibodies fail to block early events of virological synapses but inhibit HIV spread between T cells. AIDS 2009; 23:183-8.
    • (2009) AIDS , vol.23 , pp. 183-188
    • Massanella, M.1    Puigdomenech, I.2    Cabrera, C.3
  • 16
    • 0031900194 scopus 로고    scopus 로고
    • Changes in lung lymphocyte populations reflect those seen in peripheral blood in HIV-1 positive individuals
    • Bofill M, Lipman M, McLaughlin JE, Johnson MA, Poulter LW. Changes in lung lymphocyte populations reflect those seen in peripheral blood in HIV-1 positive individuals. Eur Respir J 1998; 11:548-53.
    • (1998) Eur Respir J , vol.11 , pp. 548-553
    • Bofill, M.1    Lipman, M.2    McLaughlin, J.E.3    Johnson, M.A.4    Poulter, L.W.5
  • 17
    • 62749129872 scopus 로고    scopus 로고
    • The magnitude of interferon-γ responses to human cytomegalovirus is predictive for HIV-1 disease progression
    • Darwich L, Cabrera C, Romeu J et al. The magnitude of interferon-γ responses to human cytomegalovirus is predictive for HIV-1 disease progression. J Acquir Immune Defic Syndr 2008; 49:507-12.
    • (2008) J Acquir Immune Defic Syndr , vol.49 , pp. 507-512
    • Darwich, L.1    Cabrera, C.2    Romeu, J.3
  • 18
    • 6344269428 scopus 로고    scopus 로고
    • Vaccination in humans generates broad T cell cytokine responses
    • De Rosa SC, Lu FX, Yu J et al. Vaccination in humans generates broad T cell cytokine responses. J Immunol 2004; 173:5372-80.
    • (2004) J Immunol , vol.173 , pp. 5372-5380
    • De Rosa, S.C.1    Lu, F.X.2    Yu, J.3
  • 19
    • 0032505665 scopus 로고    scopus 로고
    • Lack of T-cell proliferative response to HIV-1 antigens after 1year of highly active antiretroviral treatment in early HIV-1 disease. Immunology study group of Spanish EARTH-1 Study
    • Plana M, Garcia F, Gallart T, Miro JM, Gatell JM. Lack of T-cell proliferative response to HIV-1 antigens after 1year of highly active antiretroviral treatment in early HIV-1 disease. Immunology study group of Spanish EARTH-1 Study. Lancet 1998; 352:1194-5.
    • (1998) Lancet , vol.352 , pp. 1194-1195
    • Plana, M.1    Garcia, F.2    Gallart, T.3    Miro, J.M.4    Gatell, J.M.5
  • 20
    • 9444255221 scopus 로고    scopus 로고
    • Demographic factors that influence the neutralizing antibody response in recipients of recombinant HIV-1 gp120 vaccines
    • Montefiori DC, Metch B, McElrath MJ, Self S, Weinhold KJ, Corey L. Demographic factors that influence the neutralizing antibody response in recipients of recombinant HIV-1 gp120 vaccines. J Infect Dis 2004; 11:1962-9.
    • (2004) J Infect Dis , vol.11 , pp. 1962-1969
    • Montefiori, D.C.1    Metch, B.2    McElrath, M.J.3    Self, S.4    Weinhold, K.J.5    Corey, L.6
  • 21
    • 43049165831 scopus 로고    scopus 로고
    • Commonly used detergents
    • A1B1:A1B3 (online).
    • Coligan JE. Commonly used detergents. Curr Protoc Protein Sci 2001; A1B1:A1B3 (online).
    • (2001) Curr Protoc Protein Sci
    • Coligan, J.E.1
  • 22
    • 0033557266 scopus 로고    scopus 로고
    • Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection
    • Haynes BF, Hale LP, Weinhold KJ et al. Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection. J Clin Invest 1999; 103:453-60.
    • (1999) J Clin Invest , vol.103 , pp. 453-460
    • Haynes, B.F.1    Hale, L.P.2    Weinhold, K.J.3
  • 23
    • 0025730077 scopus 로고
    • Early T-helper cell defects in HIV infection
    • Shearer GM, Clerici M. Early T-helper cell defects in HIV infection. Aids 1991; 5:245-53.
    • (1991) Aids , vol.5 , pp. 245-253
    • Shearer, G.M.1    Clerici, M.2
  • 24
    • 33745082444 scopus 로고    scopus 로고
    • Thymic volume, T-cell populations, and parameters of thymopoiesis in adolescent and adult survivors of HIV infection acquired in infancy
    • Lee JC, Boechat MI, Belzer M et al. Thymic volume, T-cell populations, and parameters of thymopoiesis in adolescent and adult survivors of HIV infection acquired in infancy. AIDS 2006; 20:667-74.
    • (2006) AIDS , vol.20 , pp. 667-674
    • Lee, J.C.1    Boechat, M.I.2    Belzer, M.3
  • 25
    • 79952116427 scopus 로고    scopus 로고
    • Improved thymic index, density and output in HIV-infected patients following low-dose growth hormone therapy: a placebo controlled study
    • Hansen BR, Kolte L, Haugaard SB et al. Improved thymic index, density and output in HIV-infected patients following low-dose growth hormone therapy: a placebo controlled study. AIDS 2009; 23:2123-31.
    • (2009) AIDS , vol.23 , pp. 2123-2131
    • Hansen, B.R.1    Kolte, L.2    Haugaard, S.B.3
  • 26
    • 73149113364 scopus 로고    scopus 로고
    • Influence of a vaccination schedule on viral load rebound and immune responses in successfully treated HIV-infected patients
    • Castro P, Plana M, Gonzalez R et al. Influence of a vaccination schedule on viral load rebound and immune responses in successfully treated HIV-infected patients. AIDS Res Hum Retroviruses 2009; 25:1249-59.
    • (2009) AIDS Res Hum Retroviruses , vol.25 , pp. 1249-1259
    • Castro, P.1    Plana, M.2    Gonzalez, R.3
  • 27
    • 0037128660 scopus 로고    scopus 로고
    • Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood
    • Kimmig S, Przybylski GK, Schmidt CA, Laurisch K, Mowes B, Radbruch A, Thiel A. Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood. J Exp Med 2002; 195:789-94.
    • (2002) J Exp Med , vol.195 , pp. 789-794
    • Kimmig, S.1    Przybylski, G.K.2    Schmidt, C.A.3    Laurisch, K.4    Mowes, B.5    Radbruch, A.6    Thiel, A.7
  • 30
    • 0347382282 scopus 로고    scopus 로고
    • - NK cell subset and NK cell interferon-γ production during antiretroviral therapy for HIV-1: partial recovery by human growth hormone
    • - NK cell subset and NK cell interferon-γ production during antiretroviral therapy for HIV-1: partial recovery by human growth hormone. Clin Exp Immunol 2003; 134:470-6.
    • (2003) Clin Exp Immunol , vol.134 , pp. 470-476
    • Goodier, M.R.1    Imami, N.2    Moyle, G.3    Gazzard, B.4    Gotch, F.5
  • 31
    • 10744227590 scopus 로고    scopus 로고
    • + regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens
    • + regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens. J Virol 2004; 78:2454-9.
    • (2004) J Virol , vol.78 , pp. 2454-2459
    • Aandahl, E.M.1    Michaelsson, J.2    Moretto, W.J.3    Hecht, F.M.4    Nixon, D.F.5
  • 32
    • 0242320524 scopus 로고    scopus 로고
    • Disrupting T-cell homeostasis: how HIV-1 infection causes disease
    • Douek DC. Disrupting T-cell homeostasis: how HIV-1 infection causes disease. AIDS Rev 2003; 5:172-7.
    • (2003) AIDS Rev , vol.5 , pp. 172-177
    • Douek, D.C.1
  • 33
    • 0032729177 scopus 로고    scopus 로고
    • The increased CD38 expressed by lymphocytes infected with HIV-1 is a fully active NADase
    • Bofill M, Parkhouse RM. The increased CD38 expressed by lymphocytes infected with HIV-1 is a fully active NADase. Eur J Immunol 1999; 29:3583-7.
    • (1999) Eur J Immunol , vol.29 , pp. 3583-3587
    • Bofill, M.1    Parkhouse, R.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.