Immuno-PCR: A promising ultrasensitive diagnostic method to detect antigens and antibodies

Trends in Microbiology

Volumn 19, Issue 6, 2011, Pages 295-302

  Malou, Nada ^a   Raoult, Didier ^a  

^a AIX MARSEILLE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN P24; BACTERIAL ANTIGEN; GOLD NANOPARTICLE; HEPATITIS B SURFACE ANTIGEN; NEUROTOXIN; PRION PROTEIN; PROTEIN ANTIBODY; SHIGA TOXIN; STREPTAVIDIN; VIRUS ANTIGEN;

ANTIBODY DETECTION; ANTIGEN DETECTION; DIAGNOSTIC PROCEDURE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; INTERMETHOD COMPARISON; LIMIT OF DETECTION; MAGNETOSOME; MOLECULAR DYNAMICS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVIEW;

ANIMALS; ANTIBODIES; ANTIGENS, BACTERIAL; ANTIGENS, VIRAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INFECTION; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

EID: 79957826149     PISSN: 0966842X     EISSN: 18784380     Source Type: Journal    
DOI: 10.1016/j.tim.2011.03.004     Document Type: Review

References (56)

1. Houpikian P., Raoult D. Diagnostic methods current best practices and guidelines for identification of difficult-to-culture pathogens in infective endocarditis. Infect. Dis. Clin. North Am. 2002, 16:377-392.
2. Saiki R.K., et al. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. 1985. Biotechnology 1992, 24:476-480.
3. Lequin R.M. Enzyme immunoassay (EIA)/enzyme-linked immunosorbent assay (ELISA). Clin. Chem. 2005, 51:2415-2418.
4. Brechot C., et al. Hepatitis B virus DNA in patients with chronic liver disease and negative tests for hepatitis B surface antigen. N. Engl. J. Med. 1985, 312:270-276.
5. Sano T., et al. Immuno-PCR: very sensitive antigen detection by means of specific antibody-DNA conjugates. Science 1992, 258:120-122.
6. Niemeyer C.M., et al. Immuno-PCR: high sensitivity detection of proteins by nucleic acid amplification. Trends Biotechnol. 2005, 23:208-216.
7. Barletta J., Bartolome A. Immuno-polymerase chain reaction as a unique molecular tool for detection of infectious agents. Expert Opin. Med. Diagn. 2007, 1:267-288.
8. Adler M., et al. Detection of rotavirus from stool samples using a standardized immuno-PCR (“Imperacer”) method with end-point and real-time detection. Biochem. Biophys. Res. Commun. 2005, 333:1289-1294.
9. Barletta J.M., et al. Lowering the detection limits of HIV-1 viral load using real-time immuno-PCR for HIV-1 p24 antigen. Am. J. Clin. Pathol. 2004, 122:20-27.
10. Tian P., Mandrell R. Detection of norovirus capsid proteins in faecal and food samples by a real time immuno-PCR method. J. Appl. Microbiol. 2006, 100:564-574.
11. Huang S.H., Chang T.C. Detection of Staphylococcus aureus by a sensitive immuno-PCR assay. Clin. Chem. 2004, 50:1673-1674.
12. McKie A., et al. A quantitative immuno-PCR assay for the detection of mumps-specific IgG. J. Immunol. Methods 2002, 270:135-141.
13. Ruzicka V., et al. Immuno-PCR with a commercially available avidin system. Science 1993, 260:698-699.
14. Sano T., et al. Response. Science 1993, 260:699.
15. Zhou H., et al. Universal immuno-PCR for ultra-sensitive target protein detection. Nucleic Acids Res. 1993, 21:6038-6039.
16. Barletta J., et al. Immunomagnetic quantitative immuno-PCR for detection of less than one HIV-1 virion. J. Virol. Methods 2009, 157:122-132.
17. Niemeyer C.M., et al. Detecting antigens by quantitative immuno-PCR. Nat. Protoc. 2007, 2:1918-1930.
18. Adler M., et al. Sensitivity by combination: immuno-PCR and related technologies. Analyst 2008, 133:702-718.
19. Gupta A.K., Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 2005, 26:3995-4021.
20. Nam J.M., et al. Bio-barcodes based on oligonucleotide-modified nanoparticles. J. Am. Chem. Soc. 2002, 124:3820-3821.
21. Nam J.M., et al. Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins. Science 2003, 301:1884-1886.
22. Wacker R., et al. Magneto immuno-PCR: a novel immunoassay based on biogenic magnetosome nanoparticles. Biochem. Biophys. Res. Commun. 2007, 357:391-396.
23. Chen L., et al. Gold nanoparticle enhanced immuno-PCR for ultrasensitive detection of Hantaan virus nucleocapsid protein. J. Immunol. Methods 2009, 346:64-70.
24. Perez J.W., et al. Detection of respiratory syncytial virus using nanoparticle amplified immuno-polymerase chain reaction. Anal. Biochem. 2011, 410:141-148.
25. Guo Y.C., et al. Phage display mediated immuno-PCR. Nucleic Acids Res. 2006, 34:e62.
26. Morin I., et al. Ultrasensitive detection of antibodies using a new Tus-Ter-lock immunoPCR system. Mol. Biosystems 2010, 6:1173-1175.
27. Liang H., et al. A highly sensitive immuno-PCR assay for detecting group A Streptococcus. J. Immunol. Methods 2003, 279:101-110.
28. Schupbach J., et al. Use of HIV-1 p24 as a sensitive, precise and inexpensive marker for infection, disease progression and treatment failure. Int. J. Antimicrob. Agents 2000, 16:441-445.
29. Barletta J. Applications of real-time immuno-polymerase chain reaction (rt-IPCR) for the rapid diagnoses of viral antigens and pathologic proteins. Mol. Aspects Med. 2006, 27:224-253.
30. Hoofnagle J.H., et al. Chronic type B hepatitis and the “healthy” HBsAg carrier state. Hepatology 1987, 7:758-763.
31. Cao Y., et al. In-situ immuno-PCR to detect antigens. Lancet 2000, 356:1002-1003.
32. Deng M.J., et al. A highly sensitive immuno-PCR assay for detection of H5N1 avian influenza virus. Mol. Biol. Rep. 2010, 38:1941-1948.
33. McKie A., et al. Development of a quantitative immuno-PCR assay and its use to detect mumps-specific IgG in serum. J. Immunol. Methods 2002, 261:167-175.
34. Maia M., et al. Development of a two-site immuno-PCR assay for hepatitis B surface antigen. J. Virol. Methods 1995, 52:273-286.
35. Mweene A.S., et al. Development of immuno-PCR for diagnosis of bovine herpes virus 1 infection. J. Clin. Microbiol. 1996, 34:748-750.
36. Chye S.M., et al. Immuno-PCR for detection of antigen to Angiostrongylus cantonensis circulating fifth-stage worms. Clin. Chem. 2004, 50:51-57.
37. Ozaki H., et al. A rapid and highly sensitive method for diagnosis of equine influenza by antigen detection using immuno-PCR. Jpn. J. Vet. Res. 2001, 48:187-195.
38. Kakizaki E., et al. Detection of bacterial antigens using immuno-PCR. Lett. Appl. Microbiol. 1996, 23:101-103.
39. Chang T.C., Huang S.H. A modified immuno-polymerase chain reaction for the detection of beta-glucuronidase from Escherichia coli. J. Immunol. Methods 1997, 208:35-42.
40. Zhang G., Pan Q. Identification of Bacteroides fragilis by a modified immuno-polymerase chain reaction (miPCR), using a specific monoclonal antibody. Anaerobe 1998, 4:189-196.
41. Barletta J.M., et al. Detection of ultra-low levels of pathologic prion protein in scrapie infected hamster brain homogenates using real-time immuno-PCR. J. Virol. Methods 2005, 127:154-164.
42. Gofflot S., et al. Immuno-quantitative polymerase chain reaction for detection and quantitation of prion protein. J. Immunoassay Immunochem. 2004, 25:241-258.
43. Gofflot S., et al. Immunoquantitative PCR for prion protein detection in sporadic Creutzfeldt-Jakob disease. Clin. Chem. 2005, 51:1605-1611.
44. Zhang W., et al. New immuno-PCR assay for detection of low concentrations of shiga toxin 2 and its variants. J. Clin. Microbiol. 2008, 46:1292-1297.
45. Chao H.Y., et al. A highly sensitive immuno-polymerase chain reaction assay for Clostridium botulinum neurotoxin type A. Toxicon 2004, 43:27-34.
46. Fischer A., et al. A quantitative real-time immuno-PCR approach for detection of staphylococcal enterotoxins. J. Mol. Med. 2007, 85:461-469.
47. Allen R.C., et al. An immuno-PCR method for detecting Bacillus thuringiensis Cry1Ac toxin. J. Immunol. Methods 2006, 308:109-115.
48. Niemeyer C.M., et al. Nanostructured DNA-protein aggregates consisting of covalent oligonucleotide-streptavidin conjugates. Bioconjug. Chem. 2001, 12:364-371.
49. Niemeyer C.M., et al. Self-assembly of DNA-streptavidin nanostructures and their use as reagents in immuno-PCR. Nucleic Acids Res. 1999, 27:4553-4561.
50. Niemeyer C.M., et al. Supramolecular nanocircles consisting of streptavidin and DNA. Angew. Chem. Int. Ed. Engl. 2000, 39:3055-3059.
51. Niemeyer C.M., et al. Supramolecular DNA-streptavidin nanocircles with a covalently attached oligonucleotide moiety. J. Biomol. Struct. Dyn. 2002, 20:223-230.
52. Sims P.W., et al. Immunopolymerase chain reaction using real-time polymerase chain reaction for detection. Anal. Biochem. 2000, 281:230-232.
53. Takeda S., et al. Site-specific conjugation of oligonucleotides to the C-terminus of recombinant protein by expressed protein ligation. Bioorg. Med. Chem. Lett. 2004, 14:2407-2410.
54. Lovrinovic M., et al. Synthesis of protein-nucleic acid conjugates by expressed protein ligation. Chem. Commun. (Camb.) 2003, 7:822-823.
55. Christopoulos T.K., Chiu N.H. Expression immunoassay. Antigen quantitation using antibodies labeled with enzyme-coding DNA fragments. Anal. Chem. 1995, 67:4290-4294.
56. Schweitzer B., et al. Inaugural article: immunoassays with rolling circle DNA amplification: a versatile platform for ultrasensitive antigen detection. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:10113-10119.