Changes in PLA 2 activity after interacting with anti-inflammatory drugs and model membranes: Evidence for the involvement of tryptophan residues

Chemistry and Physics of Lipids

Volumn 164, Issue 4, 2011, Pages 292-299

  Gaspar, Diana ^a   Lúcio, Marlene ^a   Rocha, Sandra ^a   Lima, J L F Costa ^a   Reis, Salette ^a  

^a UNIVERSITY OF PORTO   (Portugal)

Author keywords

ADIFAB; Liposomes; NSAIDs; PLA 2 inhibition; Tryptophan fluorescence quenching and circular dichroism

Indexed keywords

FATTY ACID BINDING PROTEIN; MELOXICAM; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHOLIPASE A2; TENOXICAM; TRYPTOPHAN;

ARTICLE; ARTIFICIAL MEMBRANE; CIRCULAR DICHROISM; DRUG PROTEIN BINDING; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INHIBITION; FLUORESCENCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN HYDROLYSIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIOCATALYSIS; COBRA; COBRA VENOMS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROLYSIS; MEMBRANES, ARTIFICIAL; MODELS, MOLECULAR; PHOSPHOLIPASES A2; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTOPHAN;

EID: 79957795877     PISSN: 00093084     EISSN: 18732941     Source Type: Journal    
DOI: 10.1016/j.chemphyslip.2011.03.003     Document Type: Article

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