The N-terminal α-helix of pancreatic phospholipase A2 determines productive-mode orientation of the enzyme at the membrane surface

Journal of Molecular Biology

Volumn 344, Issue 1, 2004, Pages 71-89

  Qin, Shan ^a   Pande, Abhay H ^a   Nemec, Kathleen N ^a   Tatulian, Suren A ^a  

^a UNIVERSITY OF CENTRAL FLORIDA   (United States)

Author keywords

interfacial activation; membrane binding; orientation; polarized infrared spectroscopy

Indexed keywords

PHOSPHOLIPASE A2;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; INFRARED SPECTROSCOPY; MEMBRANE BINDING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FUNCTION;

EID: 7044269246     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.09.034     Document Type: Article

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