Modelling of serotonin reuptake inhibitory and histamine H3 antagonistic activity of piperazine and diazepane amides: QSAR rationales for co-optimization of the activity profiles

SAR and QSAR in Environmental Research

Volumn 22, Issue 3-4, 2011, Pages 365-383

  Sharma, B K ^a   Singh, P ^a   Shekhawat, M ^a   Sarbhai, K ^a   Prabhakar, Y S ^b  

^a SK Government College   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Combinatorial protocol in multiple linear regression (CP MLR); Human dopamine transporter (hDAT); Human norepinephrine transporter (hNET); Human serotonin reuptake transporter (hSERT); PLS analysis; Rat serotonin reuptake transporter (rSERT)

Indexed keywords

AMIDES; COMPUTATIONAL CHEMISTRY; LEAST SQUARES APPROXIMATIONS; MOLECULAR GRAPHICS;

ANTAGONISTIC ACTIVITY; COMBINATORIAL PROTOCOL IN MULTIPLE LINEAR REGRESSION; DOPAMINE TRANSPORTERS; HISTAMINES; HUMAN DOPAMINE TRANSPORTER; HUMAN NOREPINEPHRINE TRANSPORTER; HUMAN SEROTONIN REUPTAKE TRANSPORTER; MULTIPLE LINEAR REGRESSIONS; PARTIAL LEAST SQUARE ANALYSIS; RAT SEROTONIN REUPTAKE TRANSPORTER;

MULTIPLE LINEAR REGRESSION;

RATTUS;

EID: 79957789348     PISSN: 1062936X     EISSN: 1029046X     Source Type: Journal    
DOI: 10.1080/1062936X.2011.569895     Document Type: Article

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