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Volumn 16, Issue 2, 2011, Pages

Maximum imaging depth of two-photon autofluorescence microscopy in epithelial tissues

Author keywords

Autofluorescence microscopy; Deep imaging; Nonlinear microscopy; Optical biopsy; Two photon

Indexed keywords

AUTOFLUORESCENCE MICROSCOPY; DEEP IMAGING; NONLINEAR MICROSCOPY; OPTICAL BIOPSIES; TWO PHOTON;

EID: 79957724436     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3548646     Document Type: Article
Times cited : (60)

References (57)
  • 1
    • 0025342635 scopus 로고
    • 2-photon laser scanning fluorescence microscopy
    • W. Denk, J. Strickler, and W. Webb, "2-Photon laser scanning fluorescence microscopy," Science 248, 73-76 (1990).
    • (1990) Science , vol.248 , pp. 73-76
    • Denk, W.1    Strickler, J.2    Webb, W.3
  • 2
    • 0030927012 scopus 로고    scopus 로고
    • Multiphoton excitation fluorescence microscopy and spectroscopy of in vivo human skin
    • B. R. Masters, P. T. So, and E. Gratton, "Multiphoton excitation fluorescence microscopy and spectroscopy of In vivo human skin," Biophys. J. 72, 2405-2412 (1997).
    • (1997) Biophys. J. , vol.72 , pp. 2405-2412
    • Masters, B.R.1    So, P.T.2    Gratton, E.3
  • 3
    • 0141644208 scopus 로고    scopus 로고
    • High-resolution multiphoton tomography of human skin with subcellular spatial resolution and picosecond time resolution
    • K. Koenig and I. Riemann, "High-resolution multiphoton tomography of human skin with subcellular spatial resolution and picosecond time resolution," J. Biomedi. Opt. 8, 432-439 (2003).
    • (2003) J. Biomedi. Opt. , vol.8 , pp. 432-439
    • Koenig, K.1    Riemann, I.2
  • 4
    • 0037795542 scopus 로고    scopus 로고
    • Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation
    • W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, "Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation," Proc. Nat. Acad. Sci. U.S.A. 100, 7075-7080 (2003).
    • (2003) Proc. Nat. Acad. Sci. U.S.A. , vol.100 , pp. 7075-7080
    • Zipfel, W.R.1    Williams, R.M.2    Christie, R.3    Nikitin, A.Y.4    Hyman, B.T.5    Webb, W.W.6
  • 5
    • 13944263932 scopus 로고    scopus 로고
    • Multiphoton microscopy of endogenous fluorescence differentiates normal, precan-cerous, and cancerous squamous epithelial tissues
    • M. C. Skala, J. M. Squirrell, K. M. Vrotsos, J. C. Eickhoff, A. Gendron-Fitzpatrick, K. W. Eliceiri, and N. Ramanujam, "Multiphoton microscopy of endogenous fluorescence differentiates normal, precan-cerous, and cancerous squamous epithelial tissues," Cancer Res. 65, 1180-1186 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 1180-1186
    • Skala, M.C.1    Squirrell, J.M.2    Vrotsos, K.M.3    Eickhoff, J.C.4    Gendron-Fitzpatrick, A.5    Eliceiri, K.W.6    Ramanujam, N.7
  • 7
    • 33749618132 scopus 로고    scopus 로고
    • Discrimination of basal cell carcinoma from normal dermal stroma by quantitative multiphoton imaging
    • S. Lin, S. Jee, C. Kuo, R. Wu, W. Lin, J. Chen, Y. Liao, C. Hsu, T. Tsai, et al. "Discrimination of basal cell carcinoma from normal dermal stroma by quantitative multiphoton imaging," Opt. Lett. 31, 2756-2758 (2006).
    • (2006) Opt. Lett. , vol.31 , pp. 2756-2758
    • Lin, S.1    Jee, S.2    Kuo, C.3    Wu, R.4    Lin, W.5    Chen, J.6    Liao, Y.7    Hsu, C.8    Tsai, T.9
  • 8
    • 42149121969 scopus 로고    scopus 로고
    • Multiphoton laser scanning microscopy on non-melanoma skin cancer: Morphologic features for future non-invasive diagnostics
    • J. Paoli, M. Smedh, A. Wennberg, and M. B. Ericson, "Multiphoton laser scanning microscopy on non-melanoma skin cancer: Morphologic features for future non-invasive diagnostics," J. Investig. Dermatol. 128, 1248-1255 (2007).
    • (2007) J. Investig. Dermatol. , vol.128 , pp. 1248-1255
    • Paoli, J.1    Smedh, M.2    Wennberg, A.3    Ericson, M.B.4
  • 10
    • 0032614525 scopus 로고    scopus 로고
    • Video-rate confocal scanning laser microscope for imaging human tissues in vivo
    • M. Rajadhyaksha, R. R. Anderson, and R. H. Webb, "Video-rate confocal scanning laser microscope for imaging human tissues In vivo," Appl. Opt. 38, 2105-2115 (1999).
    • (1999) Appl. Opt. , vol.38 , pp. 2105-2115
    • Rajadhyaksha, M.1    Anderson, R.R.2    Webb, R.H.3
  • 11
    • 51649084037 scopus 로고    scopus 로고
    • Efficient rejection of scattered light enables deep optical sectioning in turbid media with low-numerical-aperture optics in a dual-axis confocal architecture
    • J. T. C. Liu, M. J. Mandella, J. M. Crawford, C. H. Contag, T. D. Wang, and G. S. Kino, "Efficient rejection of scattered light enables deep optical sectioning in turbid media with low-numerical-aperture optics in a dual-axis confocal architecture," J. Biomed. Opt. 13, 034020 (2008).
    • (2008) J. Biomed. Opt. , vol.13 , pp. 034020
    • Liu, J.T.C.1    Mandella, M.J.2    Crawford, J.M.3    Contag, C.H.4    Wang, T.D.5    Kino, G.S.6
  • 14
    • 0003033097 scopus 로고    scopus 로고
    • Three-dimensional confocal microscopy of human skin in vivo: Autofluorescence of human skin
    • B. Masters, "Three-dimensional confocal microscopy of human skin In vivo: autofluorescence of human skin," Bioimaging 4, 13-19 (1996).
    • (1996) Bioimaging , vol.4 , pp. 13-19
    • Masters, B.1
  • 15
    • 0000555824 scopus 로고    scopus 로고
    • Influence of optical properties on two-photon fluorescence imaging in turbid samples
    • A. K. Dunn, V. P. Wallace, M. Coleno, M. W. Berns, and B. J. Tromberg, "Influence of optical properties on two-photon fluorescence imaging in turbid samples," Appl. Opt. 39, 1194-1201 (2000).
    • (2000) Appl. Opt. , vol.39 , pp. 1194-1201
    • Dunn, A.K.1    Wallace, V.P.2    Coleno, M.3    Berns, M.W.4    Tromberg, B.J.5
  • 16
    • 0141756162 scopus 로고    scopus 로고
    • Characterizing point spread functions of two-photon fluorescence microscopy in turbid medium
    • C. Y. Dong, K. Koenig, and P. So, "Characterizing point spread functions of two-photon fluorescence microscopy in turbid medium," J. Biomed. Opt. 8, 450-459 (2003).
    • (2003) J. Biomed. Opt. , vol.8 , pp. 450-459
    • Dong, C.Y.1    Koenig, K.2    So, P.3
  • 17
    • 0000677585 scopus 로고    scopus 로고
    • Spatial distribution of two-photon-excited fluorescence in scattering media
    • J. Ying, F. Liu, and R. R. Alfano, "Spatial distribution of two-photon-excited fluorescence in scattering media," Appl. Opt. 38, 224-229 (1999).
    • (1999) Appl. Opt. , vol.38 , pp. 224-229
    • Ying, J.1    Liu, F.2    Alfano, R.R.3
  • 18
    • 33845887246 scopus 로고    scopus 로고
    • On the fundamental imaging-depth limit in two-photon microscopy
    • P. Theer, and W. Denk, "On the fundamental imaging-depth limit in two-photon microscopy," J. Opt. Soc. Am. A 23, 3139-3149 (2006).
    • (2006) J. Opt. Soc. Am. A , vol.23 , pp. 3139-3149
    • Theer, P.1    Denk, W.2
  • 19
    • 33846185542 scopus 로고    scopus 로고
    • Spatially distributed two-photon excitation fluorescence in scattering media: Experiments and time-resolved Monte Carlo simulations
    • A. Leray, C. Odin, E. Huguet, F. Amblard, and Y. L. Grand, "Spatially distributed two-photon excitation fluorescence in scattering media: Experiments and time-resolved Monte Carlo simulations," Opt. Comm. 272, 269-278 (2007).
    • (2007) Opt. Comm. , vol.272 , pp. 269-278
    • Leray, A.1    Odin, C.2    Huguet, E.3    Amblard, F.4    Grand, Y.L.5
  • 22
    • 70349201287 scopus 로고    scopus 로고
    • Imaging of epithelial tissue in vivo based on excitation of multiple endogenous nonlinear optical signals
    • D. Li, W. Zheng, and J. Y. Qu, "Imaging of epithelial tissue In vivo based on excitation of multiple endogenous nonlinear optical signals," Opt. Lett. 34, 2853-2855 (2009).
    • (2009) Opt. Lett. , vol.34 , pp. 2853-2855
    • Li, D.1    Zheng, W.2    Qu, J.Y.3
  • 23
    • 2942707779 scopus 로고    scopus 로고
    • In vivo multimodal nonlinear optical imaging of mucosal tissue
    • J. Sun, T. Shilagard, B. Bell, M. Motamedi, and G. Vargas, "In vivo multimodal nonlinear optical imaging of mucosal tissue," Opt. Express 12, 2478-2486 (2004).
    • (2004) Opt. Express , vol.12 , pp. 2478-2486
    • Sun, J.1    Shilagard, T.2    Bell, B.3    Motamedi, M.4    Vargas, G.5
  • 26
    • 0032498602 scopus 로고    scopus 로고
    • Multiphoton excitation microscopy of in vivo human skin: Functional and morphological optical biopsy based on three-dimensional imaging, lifetime measurements and fluorescence spectroscopy
    • B. R. Masters, P. T. C. So, and E. Gratton, "Multiphoton excitation microscopy of In vivo human skin: Functional and morphological optical biopsy based on three-dimensional imaging, lifetime measurements and fluorescence spectroscopy," Ann. N.Y. Acad. Sci. 838, 58-67 (1998).
    • (1998) Ann. N.Y. Acad. Sci. , vol.838 , pp. 58-67
    • Masters, B.R.1    So, P.T.C.2    Gratton, E.3
  • 27
    • 0035888959 scopus 로고    scopus 로고
    • Two-photon microscopy in brain tissue: Parameters influencing the imaging depth
    • M. Oheim, E. Beaurepaire, E. Chaigneau, J. Mertz, and S. Charpak, "Two-photon microscopy in brain tissue: Parameters influencing the imaging depth," J. Neurosci. Methods 111, 29-37 (2001).
    • (2001) J. Neurosci. Methods , vol.111 , pp. 29-37
    • Oheim, M.1    Beaurepaire, E.2    Chaigneau, E.3    Mertz, J.4    Charpak, S.5
  • 28
    • 84884316261 scopus 로고    scopus 로고
    • Optimizing fluorescence collection in multiphoton microscopy
    • J. T. Zinter and M. J. Levene, "Optimizing fluorescence collection in multiphoton microscopy," Biomed. Opt. OSA Tech. Dig., BMD70 (2008).
    • (2008) Biomed. Opt. OSA Tech. Dig. , vol.BMD70
    • Zinter, J.T.1    Levene, M.J.2
  • 29
    • 33744946245 scopus 로고    scopus 로고
    • MPScope: A versatile software suite for multiphoton microscopy
    • Q. Nguyen, P. S. Tsai, and D. Kleinfeld, "MPScope: A versatile software suite for multiphoton microscopy," J. Neurosci. Methods 156, 351-359 (2006).
    • (2006) J. Neurosci. Methods , vol.156 , pp. 351-359
    • Nguyen, Q.1    Tsai, P.S.2    Kleinfeld, D.3
  • 30
    • 0242353872 scopus 로고    scopus 로고
    • Nonlinear magic: Multiphoton microscopy in the biosciences
    • W. Zipfel, R. Williams and Webb, W. "Nonlinear magic: Multiphoton microscopy in the biosciences," Nat. Biotechnol. 21, 1368-1376 (2003).
    • (2003) Nat. Biotechnol. , vol.21 , pp. 1368-1376
    • Zipfel, W.1    Williams, R.2    Webb, W.3
  • 31
    • 1142267450 scopus 로고    scopus 로고
    • Spot size, depth-of-focus, and diffraction ring intensity formulas for truncated Gaussian beams
    • Urey, H. "Spot Size, Depth-of-Focus, and Diffraction Ring Intensity Formulas for Truncated Gaussian Beams," Appl. Opt. 43, 620-625 (2004).
    • (2004) Appl. Opt. , vol.43 , pp. 620-625
    • Urey, H.1
  • 32
    • 30944450665 scopus 로고    scopus 로고
    • Deep tissue two-photon microscopy
    • F. Helmchen and W. Denk, "Deep tissue two-photon microscopy," Nat. Methods 2, 932-940 (2005).
    • (2005) Nat. Methods , vol.2 , pp. 932-940
    • Helmchen, F.1    Denk, W.2
  • 34
    • 33744731417 scopus 로고    scopus 로고
    • Spectroscopic spectral-domain optical coherence microscopy
    • C. Xu, C. Vinegoni, T. S. Ralston, W. Luo, W. Tan, and S. A. Boppart, "Spectroscopic spectral-domain optical coherence microscopy," Opt. Lett. 31, 1079-1081 (2006).
    • (2006) Opt. Lett. , vol.31 , pp. 1079-1081
    • Xu, C.1    Vinegoni, C.2    Ralston, T.S.3    Luo, W.4    Tan, W.5    Boppart, S.A.6
  • 35
    • 67749102039 scopus 로고    scopus 로고
    • Three-dimensional computation of focused beam propagation through multiple biological cells
    • M. S. Starosta and A. K. Dunn, "Three-dimensional computation of focused beam propagation through multiple biological cells," Opt. Express 17, 12455-12469 (2009).
    • (2009) Opt. Express , vol.17 , pp. 12455-12469
    • Starosta, M.S.1    Dunn, A.K.2
  • 36
    • 84975564569 scopus 로고
    • Measurement of femtosecond pulses in the focal point of a high-numerical-aperture lens by two-photon absorption
    • M. Muller, J. Squier, and G. J. Brakenhoff, "Measurement of femtosecond pulses in the focal point of a high-numerical-aperture lens by two-photon absorption," Opt. Lett. 20, 1038-1040 (1995).
    • (1995) Opt. Lett. , vol.20 , pp. 1038-1040
    • Muller, M.1    Squier, J.2    Brakenhoff, G.J.3
  • 37
    • 0001748444 scopus 로고    scopus 로고
    • Measurement of group delay dispersion ofhigh numerical aperture objective lenses using two-photon excited fluorescence
    • J. B. Guild, C. Xu, and W. W. Webb, "Measurement of group delay dispersion ofhigh numerical aperture objective lenses using two-photon excited fluorescence," Appl. Opt. 36, 397-401 (1997).
    • (1997) Appl. Opt. , vol.36 , pp. 397-401
    • Guild, J.B.1    Xu, C.2    Webb, W.W.3
  • 38
    • 0035250943 scopus 로고    scopus 로고
    • Ultra-deep two-photon fluorescence excitation in turbid media
    • E. Beaurepaire, M. Oheim, and J. Mertz, "Ultra-deep two-photon fluorescence excitation in turbid media," Opt. Commun. 188, 25-29 (2001).
    • (2001) Opt. Commun. , vol.188 , pp. 25-29
    • Beaurepaire, E.1    Oheim, M.2    Mertz, J.3
  • 39
    • 0036827027 scopus 로고    scopus 로고
    • Derivation of a Monte Carlo method for modeling heterodyne detection in optical coherence tomography systems
    • A. Tycho, T. M. Jørgensen, H. T. Yura, and P. E. Andersen, "Derivation of a Monte Carlo method for modeling heterodyne detection in optical coherence tomography systems," Appl. Opt. 41, 6676-6691 (2002).
    • (2002) Appl. Opt. , vol.41 , pp. 6676-6691
    • Tycho, A.1    Jørgensen, T.M.2    Yura, H.T.3    Andersen, P.E.4
  • 40
    • 0036707482 scopus 로고    scopus 로고
    • Epifluorescence collection in two-photon microscopy
    • E. Beaurepaire and J. Mertz, "Epifluorescence collection in two-photon microscopy," Appl. Opt. 41, 5376-5382 (2002).
    • (2002) Appl. Opt. , vol.41 , pp. 5376-5382
    • Beaurepaire, E.1    Mertz, J.2
  • 43
    • 0000921450 scopus 로고    scopus 로고
    • Imaging properties in two-photon excitation microscopy and effects of refractive-index mismatch in thick specimens
    • C. J. de Grauw, J. M. Vroom, H. T. Van Der Voort, and H. C. Gerritsen, "Imaging properties in two-photon excitation microscopy and effects of refractive-index mismatch in thick specimens," Appl Opt 38, 5995-6003 (1999).
    • (1999) Appl Opt , vol.38 , pp. 5995-6003
    • De Grauw, C.J.1    Vroom, J.M.2    Van Der Voort, H.T.3    Gerritsen, H.C.4
  • 44
    • 0028590110 scopus 로고
    • Refractive-index-induced aberrations in 2-photon confocal fluorescence microscopy
    • H. Jacobsen, P. Hanninen, and S. Hell, "Refractive-index-induced aberrations in 2-photon confocal fluorescence microscopy," J. Microsc.-Oxford 176, 226-230 (1994).
    • (1994) J. Microsc.-oxford , vol.176 , pp. 226-230
    • Jacobsen, H.1    Hanninen, P.2    Hell, S.3
  • 45
    • 0035470979 scopus 로고    scopus 로고
    • Understanding the contributions of NADH and collagen to cervical tissue fluorescence spectra: Modeling, measurements, and implications
    • R. Drezek, K. Sokolov, U. Utzinger, I. Boiko, A. Malpica, M. Follen, and R. Richards-Kortum, "Understanding the contributions of NADH and collagen to cervical tissue fluorescence spectra: Modeling, measurements, and implications," J. Biomed. Opt. 6, 385 (2001).
    • (2001) J. Biomed. Opt. , vol.6 , pp. 385
    • Drezek, R.1    Sokolov, K.2    Utzinger, U.3    Boiko, I.4    Malpica, A.5    Follen, M.6    Richards-Kortum, R.7
  • 46
    • 42249098697 scopus 로고    scopus 로고
    • Understanding the biological basis of autofluorescence imaging for oral cancer detection: High-resolution fluorescence microscopy in viable tissue
    • I. Pavlova, M. Williams, A. El-Naggar, R. Richards-Kortum, and A. Gillenwater, "Understanding the biological basis of autofluores-cence imaging for oral cancer detection: High-resolution fluorescence microscopy in viable tissue," Clin. Cancer Res. 14, 2396-2404 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , pp. 2396-2404
    • Pavlova, I.1    Williams, M.2    El-Naggar, A.3    Richards-Kortum, R.4    Gillenwater, A.5
  • 48
    • 70349983078 scopus 로고    scopus 로고
    • Point spread function measured in human skin using two-photon fluorescence microscopy
    • S. Guldbrand, C. Simonsson, M. Smedh, and M. B. Ericson, "Point spread function measured in human skin using two-photon fluorescence microscopy," Proc. SPIE 7367, 73671R (2009).
    • (2009) Proc. SPIE , vol.7367
    • Guldbrand, S.1    Simonsson, C.2    Smedh, M.3    Ericson, M.B.4
  • 52
    • 0038813834 scopus 로고    scopus 로고
    • Multiphoton endoscopy
    • J. C. Jung, and M. J. Schnitzer, "Multiphoton endoscopy," Opt. Lett. 28, 902-904 (2003).
    • (2003) Opt. Lett. , vol.28 , pp. 902-904
    • Jung, J.C.1    Schnitzer, M.J.2
  • 53
    • 17444366226 scopus 로고    scopus 로고
    • Simultaneous spatial and temporal focusing of femtosecond pulses
    • G. Zhu, J. van Howe, M. Durst, W. Zipfel, and C. Xu, "Simultaneous spatial and temporal focusing of femtosecond pulses," Opt. Express 13, 2153-2159 (2005).
    • (2005) Opt. Express , vol.13 , pp. 2153-2159
    • Zhu, G.1    Van Howe, J.2    Durst, M.3    Zipfel, W.4    Xu, C.5
  • 54
    • 17444392148 scopus 로고    scopus 로고
    • Scanningless depth-resolved microscopy
    • D. Oron, E. Tal, and Y. Silberberg, "Scanningless depth-resolved microscopy," Opt. Express 13, 1468-1476 (2005).
    • (2005) Opt. Express , vol.13 , pp. 1468-1476
    • Oron, D.1    Tal, E.2    Silberberg, Y.3
  • 55
    • 38949112902 scopus 로고    scopus 로고
    • Enhanced background rejection in thick tissue with differential- aberration two-photon microscopy
    • A. Leray, K. Lillis, and J. Mertz, "Enhanced background rejection in thick tissue with differential-aberration two-photon microscopy," Biophys. J. 94, 1449-1458 (2008).
    • (2008) Biophys. J. , vol.94 , pp. 1449-1458
    • Leray, A.1    Lillis, K.2    Mertz, J.3
  • 56
    • 21244441043 scopus 로고    scopus 로고
    • Contrast and depth enhancement in two-photon microscopy of human skin ex vivo by use of optical clearing agents
    • R. Cicchi, D. Sampson, D. Massi, and F. Pavone, "Contrast and depth enhancement in two-photon microscopy of human skin ex vivo by use of optical clearing agents," Opt. Express 13, 2337-2344 (2005).
    • (2005) Opt. Express , vol.13 , pp. 2337-2344
    • Cicchi, R.1    Sampson, D.2    Massi, D.3    Pavone, F.4
  • 57
    • 68349144553 scopus 로고    scopus 로고
    • Deep tissue multiphoton microscopy using longer wavelength excitation
    • D. Kobat, M. E. Durst, N. Nishimura, A. W. Wong, C. B. Schaffer, and C. Xu, "Deep tissue multiphoton microscopy using longer wavelength excitation," Opt. Express 17, 13354-13364 (2009).
    • (2009) Opt. Express , vol.17 , pp. 13354-13364
    • Kobat, D.1    Durst, M.E.2    Nishimura, N.3    Wong, A.W.4    Schaffer, C.B.5    Xu, C.6


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