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Volumn 31, Issue 5, 2011, Pages 347-355

Nutritional supplementation of hop rho iso-alpha acids, berberine, vitamin D3, and vitamin K1 produces a favorable bone biomarker profile supporting healthy bone metabolism in postmenopausal women with metabolic syndrome

Author keywords

Bone turnover; Dietary supplement; Humulus lupulus; Kinase modulation; Mediterranean diet; Osteocalcin; Phytochemicals; Postmenopausal women; Randomized clinical trial

Indexed keywords

BERBERINE; BIOLOGICAL MARKER; CARBOXY TERMINAL TELOPEPTIDE; COLECALCIFEROL; OSTEOCALCIN; PHYTOMENADIONE; SOMATOMEDIN C;

EID: 79957683656     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2011.03.016     Document Type: Article
Times cited : (21)

References (49)
  • 2
    • 0037463608 scopus 로고    scopus 로고
    • The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994
    • Park Y.W., Zhu S., Palaniappan L., Heshka S., Carnethon M.R., Heymsfield S.B. The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994. Arch Intern Med 2003, 163:427-436.
    • (2003) Arch Intern Med , vol.163 , pp. 427-436
    • Park, Y.W.1    Zhu, S.2    Palaniappan, L.3    Heshka, S.4    Carnethon, M.R.5    Heymsfield, S.B.6
  • 3
    • 77956566543 scopus 로고    scopus 로고
    • Sex, menopause, metabolic syndrome, and all-cause and cause-specific mortality-cohort analysis from the Third National Health and Nutrition Examination Survey
    • Lin J.W., Caffrey J.L., Chang M.H., Lin Y.S. Sex, menopause, metabolic syndrome, and all-cause and cause-specific mortality-cohort analysis from the Third National Health and Nutrition Examination Survey. J Clin Endocrinol Metab 2010, 95:4258-4267.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 4258-4267
    • Lin, J.W.1    Caffrey, J.L.2    Chang, M.H.3    Lin, Y.S.4
  • 4
    • 0022648104 scopus 로고
    • Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors
    • Bertolini D.R., Nedwin G.E., Bringman T.S., Smith D.D., Mundy G.R. Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors. Nature 1986, 319:516-518.
    • (1986) Nature , vol.319 , pp. 516-518
    • Bertolini, D.R.1    Nedwin, G.E.2    Bringman, T.S.3    Smith, D.D.4    Mundy, G.R.5
  • 6
    • 0025259989 scopus 로고
    • IL-6 is produced by osteoblasts and induces bone resorption
    • Ishimi Y., Miyaura C., Jin C.H., Akatsu T., Abe E., Nakamura Y., et al. IL-6 is produced by osteoblasts and induces bone resorption. J Immunol 1990, 145:3297-3303.
    • (1990) J Immunol , vol.145 , pp. 3297-3303
    • Ishimi, Y.1    Miyaura, C.2    Jin, C.H.3    Akatsu, T.4    Abe, E.5    Nakamura, Y.6
  • 7
    • 27444443876 scopus 로고    scopus 로고
    • Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
    • Grundy S.M., Cleeman J.I., Daniels S.R., Donato K.A., Eckel R.H., Franklin B.A., et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005, 112:2735-2752.
    • (2005) Circulation , vol.112 , pp. 2735-2752
    • Grundy, S.M.1    Cleeman, J.I.2    Daniels, S.R.3    Donato, K.A.4    Eckel, R.H.5    Franklin, B.A.6
  • 8
    • 35248866268 scopus 로고    scopus 로고
    • Bone metabolism and the cardiometabolic syndrome: pathophysiologic insights
    • McFarlane S.I. Bone metabolism and the cardiometabolic syndrome: pathophysiologic insights. J Cardiometab Syndr 2006, 1:53-57.
    • (2006) J Cardiometab Syndr , vol.1 , pp. 53-57
    • McFarlane, S.I.1
  • 9
    • 35848970057 scopus 로고    scopus 로고
    • Diet, nutrition, and bone health
    • Cashman K.D. Diet, nutrition, and bone health. J Nutr 2007, 137:2507S-2512S.
    • (2007) J Nutr , vol.137
    • Cashman, K.D.1
  • 12
    • 33745622459 scopus 로고    scopus 로고
    • Fruit and vegetable intakes and bone mineral status: a cross sectional study in 5 age and sex cohorts
    • Prynne C.J., Mishra G.D., O'Connell M.A., Muniz G., Laskey M.A., Yan L., et al. Fruit and vegetable intakes and bone mineral status: a cross sectional study in 5 age and sex cohorts. Am J Clin Nutr 2006, 83:1420-1428.
    • (2006) Am J Clin Nutr , vol.83 , pp. 1420-1428
    • Prynne, C.J.1    Mishra, G.D.2    O'Connell, M.A.3    Muniz, G.4    Laskey, M.A.5    Yan, L.6
  • 13
    • 66849111911 scopus 로고    scopus 로고
    • Low-fat, increased fruit, vegetable, and grain dietary pattern, fractures, and bone mineral density: the Women's Health Initiative Dietary Modification Trial
    • McTiernan A., Wactawski-Wende J., Wu L., Rodabough R.J., Watts N.B., Tylavsky F., et al. Low-fat, increased fruit, vegetable, and grain dietary pattern, fractures, and bone mineral density: the Women's Health Initiative Dietary Modification Trial. Am J Clin Nutr 2009, 89:1864-1876.
    • (2009) Am J Clin Nutr , vol.89 , pp. 1864-1876
    • McTiernan, A.1    Wactawski-Wende, J.2    Wu, L.3    Rodabough, R.J.4    Watts, N.B.5    Tylavsky, F.6
  • 14
    • 33846247427 scopus 로고    scopus 로고
    • Dietary glycemic load, whole grains, and systemic inflammation in diabetes: the epidemiological evidence
    • Qi L., Hu F.B. Dietary glycemic load, whole grains, and systemic inflammation in diabetes: the epidemiological evidence. Curr Opin Lipidol 2007, 18:3-8.
    • (2007) Curr Opin Lipidol , vol.18 , pp. 3-8
    • Qi, L.1    Hu, F.B.2
  • 15
    • 77953753026 scopus 로고    scopus 로고
    • Mediterranean diet and the metabolic syndrome: the end of the beginning
    • Esposito K, Giugliano D. Mediterranean diet and the metabolic syndrome: the end of the beginning. Metab Syndr Relat Disord 8:197-200.
    • Metab Syndr Relat Disord , vol.8 , pp. 197-200
    • Esposito, K.1    Giugliano, D.2
  • 16
    • 72749105175 scopus 로고    scopus 로고
    • Mediterranean-style dietary pattern, reduced risk of metabolic syndrome traits, and incidence in the Framingham Offspring Cohort
    • Rumawas M.E., Meigs J.B., Dwyer J.T., McKeown N.M., Jacques P.F. Mediterranean-style dietary pattern, reduced risk of metabolic syndrome traits, and incidence in the Framingham Offspring Cohort. Am J Clin Nutr 2009, 90:1608-1614.
    • (2009) Am J Clin Nutr , vol.90 , pp. 1608-1614
    • Rumawas, M.E.1    Meigs, J.B.2    Dwyer, J.T.3    McKeown, N.M.4    Jacques, P.F.5
  • 17
    • 0031870952 scopus 로고    scopus 로고
    • Bone turnover and insulin-like growth factor I levels increase after improved glycemic control in noninsulin-dependent diabetes mellitus
    • Rosato M.T., Schneider S.H., Shapses S.A. Bone turnover and insulin-like growth factor I levels increase after improved glycemic control in noninsulin-dependent diabetes mellitus. Calcif Tissue Int 1998, 63:107-111.
    • (1998) Calcif Tissue Int , vol.63 , pp. 107-111
    • Rosato, M.T.1    Schneider, S.H.2    Shapses, S.A.3
  • 18
    • 42149139074 scopus 로고    scopus 로고
    • Altered bone metabolism in inflammatory disease: role for nutrition
    • Cashman K.D. Altered bone metabolism in inflammatory disease: role for nutrition. Proc Nutr Soc 2008, 67:196-205.
    • (2008) Proc Nutr Soc , vol.67 , pp. 196-205
    • Cashman, K.D.1
  • 19
    • 77956042807 scopus 로고    scopus 로고
    • Hop rho iso-alpha acids, berberine, vitamin D(3) and vitamin K (1) favorably impact biomarkers of bone turnover in postmenopausal women in a 14-week trial
    • Holick M.F., Lamb J.J., Lerman R.H., Konda V.R., Darland G., Minich D.M., et al. Hop rho iso-alpha acids, berberine, vitamin D(3) and vitamin K (1) favorably impact biomarkers of bone turnover in postmenopausal women in a 14-week trial. J Bone Miner Metab 2009, 28:342-350.
    • (2009) J Bone Miner Metab , vol.28 , pp. 342-350
    • Holick, M.F.1    Lamb, J.J.2    Lerman, R.H.3    Konda, V.R.4    Darland, G.5    Minich, D.M.6
  • 20
    • 77953757298 scopus 로고    scopus 로고
    • Antidiabetic screening of commercial botanical products in 3T3-L1 adipocytes and db/db mice
    • Babish J.G., Pacioretty L.M., Bland J.S., Minich D.M., Hu J., Tripp M.L. Antidiabetic screening of commercial botanical products in 3T3-L1 adipocytes and db/db mice. J Med Food 2010, 13:535-547.
    • (2010) J Med Food , vol.13 , pp. 535-547
    • Babish, J.G.1    Pacioretty, L.M.2    Bland, J.S.3    Minich, D.M.4    Hu, J.5    Tripp, M.L.6
  • 22
    • 70349251325 scopus 로고    scopus 로고
    • Rho iso-alpha acids from hops inhibit the GSK-3/NF-kappaB pathway and reduce inflammatory markers associated with bone and cartilage degradation
    • Konda V.R., Desai A., Darland G., Bland J.S., Tripp M.L. Rho iso-alpha acids from hops inhibit the GSK-3/NF-kappaB pathway and reduce inflammatory markers associated with bone and cartilage degradation. J Inflamm (Lond) 2009, 6:26.
    • (2009) J Inflamm (Lond) , vol.6 , pp. 26
    • Konda, V.R.1    Desai, A.2    Darland, G.3    Bland, J.S.4    Tripp, M.L.5
  • 23
    • 34250186987 scopus 로고    scopus 로고
    • Hop and modified hop extracts have potent in vitro anti-inflammatory properties
    • Tripp M., Darland G., Lerman R., Lukaczer D., Bland J., Babish J. Hop and modified hop extracts have potent in vitro anti-inflammatory properties. Acta Hort 2005, 668:217-227.
    • (2005) Acta Hort , vol.668 , pp. 217-227
    • Tripp, M.1    Darland, G.2    Lerman, R.3    Lukaczer, D.4    Bland, J.5    Babish, J.6
  • 24
    • 37648999717 scopus 로고    scopus 로고
    • Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-kappaB and Akt pathways
    • Hu J.P., Nishishita K., Sakai E., Yoshida H., Kato Y., Tsukuba T., et al. Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-kappaB and Akt pathways. Eur J Pharmacol 2008, 580:70-79.
    • (2008) Eur J Pharmacol , vol.580 , pp. 70-79
    • Hu, J.P.1    Nishishita, K.2    Sakai, E.3    Yoshida, H.4    Kato, Y.5    Tsukuba, T.6
  • 25
    • 0032920740 scopus 로고    scopus 로고
    • The effect of kampo formulae on bone resorption in vitro and in vivo. II. Detailed study of berberine
    • Li H., Miyahara T., Tezuka Y., Namba T., Suzuki T., Dowaki R., et al. The effect of kampo formulae on bone resorption in vitro and in vivo. II. Detailed study of berberine. Biol Pharm Bull 1999, 22:391-396.
    • (1999) Biol Pharm Bull , vol.22 , pp. 391-396
    • Li, H.1    Miyahara, T.2    Tezuka, Y.3    Namba, T.4    Suzuki, T.5    Dowaki, R.6
  • 26
    • 68949219751 scopus 로고    scopus 로고
    • Effects of berberine on differentiation and bone resorption of osteoclasts derived from rat bone marrow cells
    • Wei P., Jiao L., Qin L.P., Yan F., Han T., Zhang Q.Y. Effects of berberine on differentiation and bone resorption of osteoclasts derived from rat bone marrow cells. Zhong Xi Yi Jie He Xue Bao 2009, 7:342-348.
    • (2009) Zhong Xi Yi Jie He Xue Bao , vol.7 , pp. 342-348
    • Wei, P.1    Jiao, L.2    Qin, L.P.3    Yan, F.4    Han, T.5    Zhang, Q.Y.6
  • 27
    • 49549111375 scopus 로고    scopus 로고
    • Growth hormone, insulin-like growth factors, and the skeleton
    • Giustina A., Mazziotti G., Canalis E. Growth hormone, insulin-like growth factors, and the skeleton. Endocr Rev 2008, 29:535-559.
    • (2008) Endocr Rev , vol.29 , pp. 535-559
    • Giustina, A.1    Mazziotti, G.2    Canalis, E.3
  • 28
    • 35449001219 scopus 로고    scopus 로고
    • Serum insulin-like growth factor-I level is associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes mellitus
    • Kanazawa I., Yamaguchi T., Yamamoto M., Yamauchi M., Yano S., Sugimoto T. Serum insulin-like growth factor-I level is associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes mellitus. Osteoporos Int 2007, 18:1675-1681.
    • (2007) Osteoporos Int , vol.18 , pp. 1675-1681
    • Kanazawa, I.1    Yamaguchi, T.2    Yamamoto, M.3    Yamauchi, M.4    Yano, S.5    Sugimoto, T.6
  • 29
    • 57049090542 scopus 로고    scopus 로고
    • Enhancement of a modified Mediterranean-style, low glycemic load diet with specific phytochemicals improves cardiometabolic risk factors in subjects with metabolic syndrome and hypercholesterolemia in a randomized trial
    • Lerman R.H., Minich D.M., Darland G., Lamb J.J., Schiltz B., Babish J.G., et al. Enhancement of a modified Mediterranean-style, low glycemic load diet with specific phytochemicals improves cardiometabolic risk factors in subjects with metabolic syndrome and hypercholesterolemia in a randomized trial. Nutr Metab (Lond) 2008, 5:29.
    • (2008) Nutr Metab (Lond) , vol.5 , pp. 29
    • Lerman, R.H.1    Minich, D.M.2    Darland, G.3    Lamb, J.J.4    Schiltz, B.5    Babish, J.G.6
  • 31
    • 0026877917 scopus 로고
    • The MOS 36-item Short-Form Health Survey (SF-36). I. Conceptual framework and item selection
    • Ware J.E., Sherbourne C.D. The MOS 36-item Short-Form Health Survey (SF-36). I. Conceptual framework and item selection. Med Care 1992, 30:473-483.
    • (1992) Med Care , vol.30 , pp. 473-483
    • Ware, J.E.1    Sherbourne, C.D.2
  • 32
    • 0032550785 scopus 로고    scopus 로고
    • Constructing a standard climacteric scale
    • Greene J.G. Constructing a standard climacteric scale. Maturitas 1998, 29:25-31.
    • (1998) Maturitas , vol.29 , pp. 25-31
    • Greene, J.G.1
  • 33
    • 2542454742 scopus 로고    scopus 로고
    • Genetic strategies for elucidating insulin-like growth factor action in bone
    • Clemens T.L., Chernausek S.D. Genetic strategies for elucidating insulin-like growth factor action in bone. Growth Horm IGF Res 2004, 14:195-199.
    • (2004) Growth Horm IGF Res , vol.14 , pp. 195-199
    • Clemens, T.L.1    Chernausek, S.D.2
  • 34
    • 0037338638 scopus 로고    scopus 로고
    • From mouse to man: redefining the role of insulin-like growth factor-I in the acquisition of bone mass
    • Yakar S., Rosen C.J. From mouse to man: redefining the role of insulin-like growth factor-I in the acquisition of bone mass. Exp Biol Med (Maywood) 2003, 228:245-252.
    • (2003) Exp Biol Med (Maywood) , vol.228 , pp. 245-252
    • Yakar, S.1    Rosen, C.J.2
  • 35
    • 14644408079 scopus 로고    scopus 로고
    • The growth hormone-insulin like growth factor axis revisited: lessons from IGF-1 and IGF-1 receptor gene targeting
    • Yakar S., Kim H., Zhao H., Toyoshima Y., Pennisi P., Gavrilova O., et al. The growth hormone-insulin like growth factor axis revisited: lessons from IGF-1 and IGF-1 receptor gene targeting. Pediatr Nephrol 2005, 20:251-254.
    • (2005) Pediatr Nephrol , vol.20 , pp. 251-254
    • Yakar, S.1    Kim, H.2    Zhao, H.3    Toyoshima, Y.4    Pennisi, P.5    Gavrilova, O.6
  • 37
    • 62849125812 scopus 로고    scopus 로고
    • Vitamin D metabolism and cardiovascular risk factors in postmenopausal women
    • Perez-Lopez F.R. Vitamin D metabolism and cardiovascular risk factors in postmenopausal women. Maturitas 2009, 62:248-262.
    • (2009) Maturitas , vol.62 , pp. 248-262
    • Perez-Lopez, F.R.1
  • 38
    • 40749094549 scopus 로고    scopus 로고
    • Power C. 25-hydroxyvitamin D, IGF-1, and metabolic syndrome at 45 years of age: a cross-sectional study in the 1958 British Birth Cohort
    • Hypponen E., Boucher B.J., Berry D.J. Power C. 25-hydroxyvitamin D, IGF-1, and metabolic syndrome at 45 years of age: a cross-sectional study in the 1958 British Birth Cohort. Diabetes 2008, 57:298-305.
    • (2008) Diabetes , vol.57 , pp. 298-305
    • Hypponen, E.1    Boucher, B.J.2    Berry, D.J.3
  • 40
  • 42
    • 15944429695 scopus 로고    scopus 로고
    • Long-term safety of bisphosphonates
    • Ott S.M. Long-term safety of bisphosphonates. J Clin Endocrinol Metab 2005, 90:1897-1899.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1897-1899
    • Ott, S.M.1
  • 43
    • 33646827389 scopus 로고    scopus 로고
    • Biochemical markers of bone turnover: part I: biochemistry and variability
    • Seibel M.J. Biochemical markers of bone turnover: part I: biochemistry and variability. Clin Biochem Rev 2005, 26:97-122.
    • (2005) Clin Biochem Rev , vol.26 , pp. 97-122
    • Seibel, M.J.1
  • 45
    • 3242781731 scopus 로고    scopus 로고
    • Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases
    • Hofbauer L.C., Schoppet M. Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases. JAMA 2004, 292:490-495.
    • (2004) JAMA , vol.292 , pp. 490-495
    • Hofbauer, L.C.1    Schoppet, M.2
  • 46
    • 75649125305 scopus 로고    scopus 로고
    • Rho-iso-alpha acids and tetrahydro-iso-alpha acids are selective protein kinase inhibitors which potently reduce inflammation in macrophages in vitro and in the collagen-induced rheumatoid arthritis model in vivo. Acta Hort
    • Tripp M.L., Konda V.R., Darland G., Desai A., Chang J.L., Carroll B.J., et al. Rho-iso-alpha acids and tetrahydro-iso-alpha acids are selective protein kinase inhibitors which potently reduce inflammation in macrophages in vitro and in the collagen-induced rheumatoid arthritis model in vivo. Acta Hort. (ISHS) 2009, 848:221-234.
    • (2009) (ISHS) , vol.848 , pp. 221-234
    • Tripp, M.L.1    Konda, V.R.2    Darland, G.3    Desai, A.4    Chang, J.L.5    Carroll, B.J.6
  • 47
    • 57049090579 scopus 로고    scopus 로고
    • Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression
    • Kong W.J., Zhang H., Song D.Q., Xue R., Zhao W., Wei J., et al. Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression. Metabolism 2009, 58:109-119.
    • (2009) Metabolism , vol.58 , pp. 109-119
    • Kong, W.J.1    Zhang, H.2    Song, D.Q.3    Xue, R.4    Zhao, W.5    Wei, J.6
  • 48
    • 77957779218 scopus 로고    scopus 로고
    • Thiazolidinediones and fractures: evidence from translating research into action for diabetes
    • Bilik D., McEwen L.N., Brown M.B., Pomeroy N.E., Kim C., Asao K., et al. Thiazolidinediones and fractures: evidence from translating research into action for diabetes. J Clin Endocrinol Metab 2010, 95:4560-4565.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 4560-4565
    • Bilik, D.1    McEwen, L.N.2    Brown, M.B.3    Pomeroy, N.E.4    Kim, C.5    Asao, K.6
  • 49
    • 58149380112 scopus 로고    scopus 로고
    • The relationship of serum osteocalcin concentration to insulin secretion, sensitivity, and disposal with hypocaloric diet and resistance training
    • Fernandez-Real J.M., Izquierdo M., Ortega F., Gorostiaga E., Gomez-Ambrosi J., Moreno-Navarrete J.M., et al. The relationship of serum osteocalcin concentration to insulin secretion, sensitivity, and disposal with hypocaloric diet and resistance training. J Clin Endocrinol Metab 2009, 94:237-245.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 237-245
    • Fernandez-Real, J.M.1    Izquierdo, M.2    Ortega, F.3    Gorostiaga, E.4    Gomez-Ambrosi, J.5    Moreno-Navarrete, J.M.6


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