Centrally mediated inhibition of local inflammation by ciliary neurotrophic factor

NeuroImmunoModulation

Volumn 4, Issue 5-6, 1997, Pages 271-276

  Meazza, Cristina ^a   Di Marco, Annalise ^b   Fruscella, Paolo ^a   Gloaguen, Isabelle ^b   Laufer, Ralph ^b   Sironi, Marina ^a   Sipe, Jean D ^c   Villa, Pia ^a,d   Romano, Maria ^a   Ghezzi, Pietro ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b IRBM   (Italy)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CNR   (Italy)

Author keywords

Ciliary neurotrophic factor; Corticosterone; Inflammation; Tumor necrosis factor

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; CORTICOSTERONE; INTERLEUKIN 6; SERUM AMYLOID A; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INFLAMMATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOUSE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL;

ADRENALECTOMY; AIR; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; CILIARY NEUROTROPHIC FACTOR; CORTICOSTERONE; EDEMA; EXUDATES AND TRANSUDATES; GENE EXPRESSION REGULATION; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INFLAMMATION; INJECTIONS, INTRAVENOUS; INJECTIONS, INTRAVENTRICULAR; INTERLEUKIN-6; MICE; NERVE TISSUE PROTEINS; PITUITARY-ADRENAL SYSTEM; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, CILIARY NEUROTROPHIC FACTOR; RECEPTORS, NERVE GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SERUM AMYLOID A PROTEIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 13144277605     PISSN: 10217401     EISSN: 14230216     Source Type: Journal    
DOI: 10.1159/000097347     Document Type: Article

References (27)

1. Fantuzzi G, Di Santo E, Sacco S, Bcnigni F, Ghczzi P: Role of the hypothalamus-pituitary-adrenal axis in the regulation of tumor necrosis factor production in mice: effect of stress and inhibition of endogenous glucocorticoids, J Immunol 1995:155:3552-3555.
2. Bcscdovsky H, Del Rcy A, Dinarcllo CA: Im-munorcgulatory feedback between intcrlcukin-I and glucocorticoid hormones, Science 1986: 233:652-654.
3. Fantuzzi G, Ghczzi P: Glucocorticoids as cytokine inhibitors: Role in neuroendocrine control and therapy of inflammatory diseases, Medial Inflamm 1993:2:263-270.
4. Catania A, Arnold J, Macaluso A, Hiltz ME, Lipton JM: Inhibition of acute inflammation in the periphery by central action of salicylates, Proc Natl Acad Sci USA 1991:88:8544-8547.
5. Lipton JM, Macaluso A, Hitz ME, Catania A: Central administration of the peptide alpha-MSH inhibits inflammation in the skin, Peptides 1991;12:795-798.
6. Williams RO, Feldmann M, Maini RM: Antitumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis, Proc Natl Acad Sci USA 1992;89:9784-9788.
7. Piguet PF, Grau GE, Hauser C, Vassalli P: Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reaction, J Exp Med 1991; 173:673- 679.
8. Bcnigni F, Villa P, Demitri MT, Sacco S, Sipc JD, Lagunowich L, Panayotalos N, Ghczzi P: Ciliary neurotrophic factor (CNTF) inhibits brain and peripheral TNF production and, in association with its soluble receptor, protects mice against LPS toxicity, Mol Med 1995:1: 568-575.
9. Bcnigni F, Fantuzzi G, Sironi M, Sacco S, Pozzi P, Dinarcllo CA, Sipc JD, Poli V, Cappelletti M, Paonessa G, Panayotalos N, Pcnnica D, Ghczzi P: Six different cytokines that share gpl30 as a receptor subunit, induce scrum amyloid A and potentiate the induction of interleukin-6 and the activation of the hypo-Ihalamus-pituitary-adrena! axis by interleukin-1. Blood 1995:87:1851-1854.
10. Davis S, YancopoulosGD: The molecular biology of the CNTF receptor, Curr Opin Ncuro-biol 1994;3:20-24.
11. Ulich TR, Fann M-J, Patterson PH, Williams JM, Samai B, Del Castillo J, Yin S, Guo K, Remick DG: Intratracheal injection of LPS and cytokines, V, LPS induces expression of LIFand LIF inhibits acute inflammation, Am J Physiol 1994;267:L442-L446.
12. Benigni F, Sacco S, Pcnnica D, Ghczzi P: Car-diotrophin-l (CT-1) inhibits TNF production in the heart and serum of LPS-trcated mice and in vitro in mouse blood cells, Am J Pathol 1996;149:1847-1850.
13. Ferràndiz ML, Foster SJ: Tumour necrosis factor production in a rat airpouch model of inflammation: role of eicosanoids, Agents Actions 1991:32:289-294.
14. Di Marco A, Gloagucn I, Graziani R, Paonessa G, Saggio I, Hudson KR, Laufcr R: Identification of CNTF residues essential for LIF receptor binding and generation of a potent CNTF receptor antagonist, Proc Natl Acad Sci USA 1996;93:9247-9252.
15. Haley TJ, McCormick WG: Pharmacological efTect produced by intracerebral injection of drugs in the conscious mice, Br J Pharmacol 1957:12:12-15.
16. Aggarwal BB, Khor VVJ, Hass PE, Moffat B, Spencer SA, Henzel J, Bringman S, Nedwin GE, Goeddel DV, Harkins RN: Human tumor necrosis factor: Production, purification and characterization, J Biol Chem 1985:260:2345-2354.
17. Sironi M, Breviario F, Proserpio P, Biondi A, Vecchi A, Van Damme J, Dejana E, Mantovani A: IL-1 stimulates IL-6 production in endothelial cells, J Immunol 1989; 142:549-553.
18. Sin YM, Chio SL: Effect of carrageenan-in-duced acute inflammation on corticosterone levels in mice, Agents actions 1990:29:196-200.
19. Turchik JB, Bomstcin DL: Role of the central nervous system in acute-phase responses to leukocytic pyrogen, Infect Immun 1980.390:439-444.
20. Uehara A, Okumura T, Kitamori S, Takasugi Y, Namaki M, Interleukin I: a cytokine that has potent antisecrctory and and anti-ulcer actions via the central nervous system, Biochem Biophvs Res Commun 1990;173:585-590.
21. Libert C, Brouckacrt P, Fiers W: Protection by al-acid glycoprotein against tumor necrosis factor-induced lethality, J Exp Med 1994; 180: 1571-1575.
22. Abernathy VJ, Webster RO, Dahms TE: C-rea-cative protein inhibits increased pulmonary vascular permeability induced by fMLP in isolated rabbit lungs, Am J Physiol 1996;271: H507-H513.
23. Wisniewski H-G, Hua J-C, Poppers DM, Naime D, Vilcck J, Cronstcin BN: TNF/IL-1-inducible protein TSG-6 potentiates plasmin inhibition by intcr-a-inhibitor and exerts a strong anti-inflammatory effect in vivo, J Immunol 1996;156:1609-1615.
24. Stöckli KA, Lottspcich F, Sendtner M, Masia-kowski P, Carrol P, Götz R, Lindholm D, Thoenen H: Molecular cloning, expression and regional distribution of rat ciliary ncurotrophic factor, Nature 1989;342:920-923.
25. Dobrea GM, Unnertall JR, Rao MS: The expression of CNTF message and immunoreac-tivity in the central and peripheral nervous system of the rat, Dev Brain Res 1992;66:209-219.
26. Guillet C, Fourcin M, Chevalier S, Pouplard A, Gascan H: ELISA detection of circulating levels of LIF, OSM, and CNTF in septic chock, Ann NY Acad Sei 1995;762:407-409.
27. Wang Z, Ren S-G, Melmed S: Hypothalamic and pituitary' leukemia inhibitors' factor gene expression in vivo: A novel endotoxin-induci-ble neuro-endocrine interface, Endocrinology 1996;137:2947-2953.