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Volumn 307, Issue 2, 2011, Pages 200-210

Insulin-like growth factor-binding protein-3 suppresses tumor growth via activation of caspase-dependent apoptosis and cross-talk with NF-κB signaling

Author keywords

Apoptosis; Caspase; Chemodrug; IGFBP 3; NF B

Indexed keywords

CASPASE; CASPASE 3; CASPASE 7; CASPASE 8; DOXORUBICIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; SOMATOMEDIN BINDING PROTEIN 3; SYNAPTOTAGMIN I; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN;

EID: 79957653825     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.04.004     Document Type: Article
Times cited : (62)

References (43)
  • 1
    • 0037203538 scopus 로고    scopus 로고
    • Nuclear factor-kappaB activation: a question of life or death
    • Shishodia S., Aggarwal B.B. Nuclear factor-kappaB activation: a question of life or death. J. Biochem. Mol. Biol. 2002, 35:28-40.
    • (2002) J. Biochem. Mol. Biol. , vol.35 , pp. 28-40
    • Shishodia, S.1    Aggarwal, B.B.2
  • 2
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl H.L. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 1999, 18:6853-6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 3
    • 0024353902 scopus 로고
    • Inhibitory diffusible factor 45 bifunctional activity as a cell growth inhibitor and as an insulin-like growth factor I-binding protein
    • Blat C., Delbe J., Villaudy J., Chatelain G., Golde A., Harel L. Inhibitory diffusible factor 45 bifunctional activity as a cell growth inhibitor and as an insulin-like growth factor I-binding protein. J. Biol. Chem. 1989, 264:12449-12454.
    • (1989) J. Biol. Chem. , vol.264 , pp. 12449-12454
    • Blat, C.1    Delbe, J.2    Villaudy, J.3    Chatelain, G.4    Golde, A.5    Harel, L.6
  • 5
    • 2442424073 scopus 로고    scopus 로고
    • Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes
    • Shukla S., Gupta S. Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes. Clin. Cancer Res. 2004, 10:3169-3178.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 3169-3178
    • Shukla, S.1    Gupta, S.2
  • 7
    • 0037351342 scopus 로고    scopus 로고
    • NF-kappa B nuclear localization and its prognostic significance in prostate cancer
    • Lessard L., Mes-Masson A.M., Lamarre L., Wall L., Lattouf J.B., Saad F. NF-kappa B nuclear localization and its prognostic significance in prostate cancer. BJU Int. 2003, 91:417-420.
    • (2003) BJU Int. , vol.91 , pp. 417-420
    • Lessard, L.1    Mes-Masson, A.M.2    Lamarre, L.3    Wall, L.4    Lattouf, J.B.5    Saad, F.6
  • 8
    • 0035849720 scopus 로고    scopus 로고
    • Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis
    • Huang S., Pettaway C.A., Uehara H., Bucana C.D., Fidler I.J. Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene 2001, 20:4188-4197.
    • (2001) Oncogene , vol.20 , pp. 4188-4197
    • Huang, S.1    Pettaway, C.A.2    Uehara, H.3    Bucana, C.D.4    Fidler, I.J.5
  • 9
    • 20444504721 scopus 로고    scopus 로고
    • Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion
    • Takada Y., Kobayashi Y., Aggarwal B.B. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion. J. Biol. Chem. 2005, 280:17203-17212.
    • (2005) J. Biol. Chem. , vol.280 , pp. 17203-17212
    • Takada, Y.1    Kobayashi, Y.2    Aggarwal, B.B.3
  • 10
    • 1542426626 scopus 로고    scopus 로고
    • Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3
    • Chendil D., Ranga R.S., Meigooni D., Sathishkumar S., Ahmed M.M. Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3. Oncogene 2004, 23:1599-1607.
    • (2004) Oncogene , vol.23 , pp. 1599-1607
    • Chendil, D.1    Ranga, R.S.2    Meigooni, D.3    Sathishkumar, S.4    Ahmed, M.M.5
  • 12
    • 0036196320 scopus 로고    scopus 로고
    • NF-kappa B activates prostate-specific antigen expression and is upregulated in androgen-independent prostate cancer
    • Chen C.D., Sawyers C.L. NF-kappa B activates prostate-specific antigen expression and is upregulated in androgen-independent prostate cancer. Mol. Cell. Biol. 2002, 22:2862-2870.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2862-2870
    • Chen, C.D.1    Sawyers, C.L.2
  • 14
    • 0028936763 scopus 로고
    • The human insulin-like growth factor (IGF) binding protein-3 inhibits the growth of fibroblasts with a targeted disruption of the IGF-I receptor gene
    • Valentinis B., Bhala A., DeAngelis T., Baserga R., Cohen P. The human insulin-like growth factor (IGF) binding protein-3 inhibits the growth of fibroblasts with a targeted disruption of the IGF-I receptor gene. Mol. Endocrinol. 1995, 9:361-367.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 361-367
    • Valentinis, B.1    Bhala, A.2    DeAngelis, T.3    Baserga, R.4    Cohen, P.5
  • 15
    • 0034748889 scopus 로고    scopus 로고
    • Mutation of three critical amino acids of the N-terminal domain of IGF-binding protein-3 essential for high affinity IGF binding
    • Buckway C.K., Wilson E.M., Ahlsen M., Bang P., Oh Y., Rosenfeld R.G. Mutation of three critical amino acids of the N-terminal domain of IGF-binding protein-3 essential for high affinity IGF binding. J. Clin. Endocrinol. Metab. 2001, 86:4943-4950.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 4943-4950
    • Buckway, C.K.1    Wilson, E.M.2    Ahlsen, M.3    Bang, P.4    Oh, Y.5    Rosenfeld, R.G.6
  • 16
    • 0034671895 scopus 로고    scopus 로고
    • Growth inhibition by insulin-like growth factor-binding protein-3 in T47D breast cancer cells requires transforming growth factor-beta (TGF-beta) and the type II TGF-beta receptor
    • Fanayan S., Firth S.M., Butt A.J., Baxter R.C. Growth inhibition by insulin-like growth factor-binding protein-3 in T47D breast cancer cells requires transforming growth factor-beta (TGF-beta) and the type II TGF-beta receptor. J. Biol. Chem. 2000, 275:39146-39151.
    • (2000) J. Biol. Chem. , vol.275 , pp. 39146-39151
    • Fanayan, S.1    Firth, S.M.2    Butt, A.J.3    Baxter, R.C.4
  • 17
    • 0030972216 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism
    • Rajah R., Valentinis B., Cohen P. Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism. J. Biol. Chem. 1997, 272:12181-12188.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12181-12188
    • Rajah, R.1    Valentinis, B.2    Cohen, P.3
  • 18
    • 20444461570 scopus 로고    scopus 로고
    • Rapid apoptosis induction by IGFBP-3 involves an insulin-like growth factor-independent nucleomitochondrial translocation of RXRalpha/Nur77
    • Lee K.W., Ma L., Yan X., Liu B., Zhang X.K., Cohen P. Rapid apoptosis induction by IGFBP-3 involves an insulin-like growth factor-independent nucleomitochondrial translocation of RXRalpha/Nur77. J. Biol. Chem. 2005, 280:16942-16948.
    • (2005) J. Biol. Chem. , vol.280 , pp. 16942-16948
    • Lee, K.W.1    Ma, L.2    Yan, X.3    Liu, B.4    Zhang, X.K.5    Cohen, P.6
  • 19
    • 76249133754 scopus 로고    scopus 로고
    • Interaction of insulin-like growth factor-binding protein-3 and BAX in mitochondria promotes male germ cell apoptosis
    • Jia Y., Lee K.W., Swerdloff R., Hwang D., Cobb L.J., Sinha Hikim A., Lue Y.H., Cohen P., Wang C. Interaction of insulin-like growth factor-binding protein-3 and BAX in mitochondria promotes male germ cell apoptosis. J. Biol. Chem. 2010, 285:1726-1732.
    • (2010) J. Biol. Chem. , vol.285 , pp. 1726-1732
    • Jia, Y.1    Lee, K.W.2    Swerdloff, R.3    Hwang, D.4    Cobb, L.J.5    Sinha Hikim, A.6    Lue, Y.H.7    Cohen, P.8    Wang, C.9
  • 20
    • 22144468077 scopus 로고    scopus 로고
    • Enhancement of tumor necrosis factor-alpha-induced growth inhibition by insulin-like growth factor-binding protein-5 (IGFBP-5), but not IGFBP-3 in human breast cancer cells
    • Butt A.J., Dickson K.A., Jambazov S., Baxter R.C. Enhancement of tumor necrosis factor-alpha-induced growth inhibition by insulin-like growth factor-binding protein-5 (IGFBP-5), but not IGFBP-3 in human breast cancer cells. Endocrinology 2005, 146:3113-3122.
    • (2005) Endocrinology , vol.146 , pp. 3113-3122
    • Butt, A.J.1    Dickson, K.A.2    Jambazov, S.3    Baxter, R.C.4
  • 21
    • 33845488341 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-kappaB
    • Williams A.C., Smartt H., H-Zadeh A.M., Macfarlane M., Paraskeva C., Collard T.J. Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-kappaB. Cell Death Differ. 2007, 14:137-145.
    • (2007) Cell Death Differ. , vol.14 , pp. 137-145
    • Williams, A.C.1    Smartt, H.2    H-Zadeh, A.M.3    Macfarlane, M.4    Paraskeva, C.5    Collard, T.J.6
  • 22
    • 8844263797 scopus 로고    scopus 로고
    • Targeting apoptosis pathways in cancer therapy
    • Fulda S., Debatin K.M. Targeting apoptosis pathways in cancer therapy. Curr. Cancer Drug Targets 2004, 4:569-576.
    • (2004) Curr. Cancer Drug Targets , vol.4 , pp. 569-576
    • Fulda, S.1    Debatin, K.M.2
  • 24
    • 16244379230 scopus 로고    scopus 로고
    • Impact of PTEN on the expression of insulin-like growth factors (IGFs) and IGF-binding proteins in human gastric adenocarcinoma cells
    • Yi H.K., Kim S.Y., Hwang P.H., Kim C.Y., Yang D.H., Oh Y., Lee D.Y. Impact of PTEN on the expression of insulin-like growth factors (IGFs) and IGF-binding proteins in human gastric adenocarcinoma cells. Biochem. Biophys. Res. Commun. 2005, 330:760-767.
    • (2005) Biochem. Biophys. Res. Commun. , vol.330 , pp. 760-767
    • Yi, H.K.1    Kim, S.Y.2    Hwang, P.H.3    Kim, C.Y.4    Yang, D.H.5    Oh, Y.6    Lee, D.Y.7
  • 25
    • 0035933725 scopus 로고    scopus 로고
    • Interaction of the hepatitis B virus X protein with the Crm1-dependent nuclear export pathway
    • Forgues M., Marrogi A.J., Spillare E.A., Wu C.G., Yang Q., Yoshida M., Wang X.W. Interaction of the hepatitis B virus X protein with the Crm1-dependent nuclear export pathway. J. Biol. Chem. 2001, 276:22797-22803.
    • (2001) J. Biol. Chem. , vol.276 , pp. 22797-22803
    • Forgues, M.1    Marrogi, A.J.2    Spillare, E.A.3    Wu, C.G.4    Yang, Q.5    Yoshida, M.6    Wang, X.W.7
  • 26
    • 0031944186 scopus 로고    scopus 로고
    • Metastatic sublines of an SV40 large T antigen immortalized human prostate epithelial cell line
    • Bae V.L., Jackson-Cook C.K., Maygarden S.J., Plymate S.R., Chen J., Ware J.L. Metastatic sublines of an SV40 large T antigen immortalized human prostate epithelial cell line. Prostate 1998, 34:275-282.
    • (1998) Prostate , vol.34 , pp. 275-282
    • Bae, V.L.1    Jackson-Cook, C.K.2    Maygarden, S.J.3    Plymate, S.R.4    Chen, J.5    Ware, J.L.6
  • 27
    • 0029202881 scopus 로고
    • Establishment, characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1
    • Hayward S.W., Dahiya R., Cunha G.R., Bartek J., Deshpande N., Narayan P. Establishment, characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1. In Vitro Cell Dev. Biol. 1995, 31:14-24.
    • (1995) In Vitro Cell Dev. Biol. , vol.31 , pp. 14-24
    • Hayward, S.W.1    Dahiya, R.2    Cunha, G.R.3    Bartek, J.4    Deshpande, N.5    Narayan, P.6
  • 30
    • 0037125383 scopus 로고    scopus 로고
    • Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer
    • Chan J.M., Stampfer M.J., Ma J., Gann P., Gaziano J.M., Pollak M., Giovannucci E. Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer. J. Natl. Cancer Inst. 2002, 94:1099-1106.
    • (2002) J. Natl. Cancer Inst. , vol.94 , pp. 1099-1106
    • Chan, J.M.1    Stampfer, M.J.2    Ma, J.3    Gann, P.4    Gaziano, J.M.5    Pollak, M.6    Giovannucci, E.7
  • 31
    • 0033531765 scopus 로고    scopus 로고
    • Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3
    • Ma J., Pollak M.N., Giovannucci E., Chan J.M., Tao Y., Hennekens C.H., Stampfer M.J. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J. Natl. Cancer Inst. 1999, 91:620-625.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 620-625
    • Ma, J.1    Pollak, M.N.2    Giovannucci, E.3    Chan, J.M.4    Tao, Y.5    Hennekens, C.H.6    Stampfer, M.J.7
  • 32
    • 0033585421 scopus 로고    scopus 로고
    • Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis
    • Yu H., Spitz M.R., Mistry J., Gu J., Hong W.K., Wu X. Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis. J. Natl. Cancer Inst. 1999, 91:151-156.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 151-156
    • Yu, H.1    Spitz, M.R.2    Mistry, J.3    Gu, J.4    Hong, W.K.5    Wu, X.6
  • 33
    • 0031897867 scopus 로고    scopus 로고
    • Differential expression of insulin-like growth factor binding proteins in high versus low gleason score prostate cancer
    • Figueroa J.A., De Raad S., Tadlock L., Speights V.O., Rinehart J.J. Differential expression of insulin-like growth factor binding proteins in high versus low gleason score prostate cancer. J. Urol. 1998, 159:1379-1383.
    • (1998) J. Urol. , vol.159 , pp. 1379-1383
    • Figueroa, J.A.1    De Raad, S.2    Tadlock, L.3    Speights, V.O.4    Rinehart, J.J.5
  • 34
    • 0036468136 scopus 로고    scopus 로고
    • Association of preoperative plasma levels of insulin-like growth factor I and insulin-like growth factor binding proteins-2 and -3 with prostate cancer invasion, progression, and metastasis
    • Shariat S.F., Lamb D.J., Kattan M.W., Nguyen C., Kim J., Beck J., Wheeler T.M., Slawin K.M. Association of preoperative plasma levels of insulin-like growth factor I and insulin-like growth factor binding proteins-2 and -3 with prostate cancer invasion, progression, and metastasis. J. Clin. Oncol. 2002, 20:833-841.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 833-841
    • Shariat, S.F.1    Lamb, D.J.2    Kattan, M.W.3    Nguyen, C.4    Kim, J.5    Beck, J.6    Wheeler, T.M.7    Slawin, K.M.8
  • 35
    • 0036682376 scopus 로고    scopus 로고
    • Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer
    • Rhodes D.R., Barrette T.R., Rubin M.A., Ghosh D., Chinnaiyan A.M. Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer. Cancer Res. 2002, 62:4427-4433.
    • (2002) Cancer Res. , vol.62 , pp. 4427-4433
    • Rhodes, D.R.1    Barrette, T.R.2    Rubin, M.A.3    Ghosh, D.4    Chinnaiyan, A.M.5
  • 36
    • 66149116716 scopus 로고    scopus 로고
    • Inhibition of constitutive activity of nuclear transcription factor kappaB sensitizes doxorubicin-resistant cells to apoptosis
    • Gangadharan C., Thoh M., Manna S.K. Inhibition of constitutive activity of nuclear transcription factor kappaB sensitizes doxorubicin-resistant cells to apoptosis. J. Cell. Biochem. 2009, 107:203-213.
    • (2009) J. Cell. Biochem. , vol.107 , pp. 203-213
    • Gangadharan, C.1    Thoh, M.2    Manna, S.K.3
  • 37
    • 33847188791 scopus 로고    scopus 로고
    • NF-kappaB inhibitors for the treatment of inflammatory diseases and cancer
    • Calzado M.A., Bacher S., Schmitz M.L. NF-kappaB inhibitors for the treatment of inflammatory diseases and cancer. Curr. Med. Chem. 2007, 14:367-376.
    • (2007) Curr. Med. Chem. , vol.14 , pp. 367-376
    • Calzado, M.A.1    Bacher, S.2    Schmitz, M.L.3
  • 38
    • 0033575220 scopus 로고    scopus 로고
    • Apoptosis promotes a caspase-induced amino-terminal truncation of IkappaBalpha that functions as a stable inhibitor of NF-kappaB
    • Reuther J.Y., Baldwin A.S. Apoptosis promotes a caspase-induced amino-terminal truncation of IkappaBalpha that functions as a stable inhibitor of NF-kappaB. J. Biol. Chem. 1999, 274:20664-20670.
    • (1999) J. Biol. Chem. , vol.274 , pp. 20664-20670
    • Reuther, J.Y.1    Baldwin, A.S.2
  • 39
    • 0036212505 scopus 로고    scopus 로고
    • Caspase cleavage product lacking amino-terminus of IkappaBalpha sensitizes resistant cells to TNF-alpha and TRAIL-induced apoptosis
    • Kim K.W., Kim B.J., Chung C.W., Jo D.G., Kim I.K., Song Y.H., Kwon Y.K., Woo H.N., Jung Y.K. Caspase cleavage product lacking amino-terminus of IkappaBalpha sensitizes resistant cells to TNF-alpha and TRAIL-induced apoptosis. J. Cell. Biochem. 2002, 85:334-345.
    • (2002) J. Cell. Biochem. , vol.85 , pp. 334-345
    • Kim, K.W.1    Kim, B.J.2    Chung, C.W.3    Jo, D.G.4    Kim, I.K.5    Song, Y.H.6    Kwon, Y.K.7    Woo, H.N.8    Jung, Y.K.9
  • 40
    • 22244449642 scopus 로고    scopus 로고
    • Caspase-mediated p65 cleavage promotes TRAIL-induced apoptosis
    • Kim H.S., Chang I., Kim J.Y., Choi K.H., Lee M.S. Caspase-mediated p65 cleavage promotes TRAIL-induced apoptosis. Cancer Res. 2005, 65:6111-6119.
    • (2005) Cancer Res. , vol.65 , pp. 6111-6119
    • Kim, H.S.1    Chang, I.2    Kim, J.Y.3    Choi, K.H.4    Lee, M.S.5
  • 41
    • 1542510615 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein 3 induces caspase-dependent apoptosis through a death receptor-mediated pathway in MCF-7 human breast cancer cells
    • Kim H.S., Ingermann A.R., Tsubaki J., Twigg S.M., Walker G.E., Oh Y. Insulin-like growth factor-binding protein 3 induces caspase-dependent apoptosis through a death receptor-mediated pathway in MCF-7 human breast cancer cells. Cancer Res. 2004, 64:2229-2237.
    • (2004) Cancer Res. , vol.64 , pp. 2229-2237
    • Kim, H.S.1    Ingermann, A.R.2    Tsubaki, J.3    Twigg, S.M.4    Walker, G.E.5    Oh, Y.6
  • 42
    • 0032937419 scopus 로고    scopus 로고
    • Characterization of insulin-like growth factor binding protein-3 (IGFBP-3) binding to human breast cancer cells: kinetics of IGFBP-3 binding and identification of receptor binding domain on the IGFBP-3 molecule
    • Yamanaka Y., Fowlkes J.L., Wilson E.M., Rosenfeld R.G., Oh Y. Characterization of insulin-like growth factor binding protein-3 (IGFBP-3) binding to human breast cancer cells: kinetics of IGFBP-3 binding and identification of receptor binding domain on the IGFBP-3 molecule. Endocrinology 1999, 140:1319-1328.
    • (1999) Endocrinology , vol.140 , pp. 1319-1328
    • Yamanaka, Y.1    Fowlkes, J.L.2    Wilson, E.M.3    Rosenfeld, R.G.4    Oh, Y.5
  • 43
    • 77956939368 scopus 로고    scopus 로고
    • Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer
    • Ingermann A.R., Yang Y.F., Han J., et al. Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer. J. Biol. Chem. 2010, 285:30233-30246.
    • (2010) J. Biol. Chem. , vol.285 , pp. 30233-30246
    • Ingermann, A.R.1    Yang, Y.F.2    Han, J.3


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