Continuous 24-h nicotinic acid infusion in rats causes FFA rebound and insulin resistance by altering gene expression and basal lipolysis in adipose tissue

American Journal of Physiology - Endocrinology and Metabolism

Volumn 300, Issue 6, 2011, Pages

  Oh, Young Taek ^a,b   Oh, Ki Sook ^a   Choi, Yong Min ^c   Jokiaho, Anne ^d   Donovan, Casey ^d   Choi, Sangdun ^c   Kang, Insug ^b   Youn, Jang H ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Kyung Hee University Hospital   (South Korea)

^c Ajou University   (South Korea)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Free fatty acids; Hypolipidemic drug; Insulin resistance; Microarray analysis; Nicotinic acid receptor; Perilipin; Phosphodiesterase; Triglyceride synthesis

Indexed keywords

CYCLIC AMP; FATTY ACID; NICOTINIC ACID; PHOSPHODIESTERASE III; SODIUM CHLORIDE;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG INFUSION; FATTY ACID BLOOD LEVEL; GENE EXPRESSION; GLUCOSE CLAMP TECHNIQUE; GLUCOSE METABOLISM; HYPERINSULINEMIA; INSULIN RESISTANCE; LIPOLYSIS; MALE; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; REBOUND; RECEPTOR DOWN REGULATION;

ADIPOSE TISSUE; ANIMALS; BLOTTING, WESTERN; CATECHOLAMINES; CORTICOSTERONE; FATTY ACIDS, NONESTERIFIED; GENE EXPRESSION; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; GLYCEROL; HYPOLIPIDEMIC AGENTS; INFUSIONS, INTRAVENOUS; INSULIN RESISTANCE; LIPASE; LIPID METABOLISM; LIPOLYSIS; MALE; MICROARRAY ANALYSIS; NIACIN; PHOSPHORYLATION; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

EID: 79957637411     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00650.2010     Document Type: Article

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