Effects of nicotinic acid on fatty acid kinetics, fuel selection, and pathways of glucose production in women

American Journal of Physiology - Endocrinology and Metabolism

Volumn 279, Issue 1 42-1, 2000, Pages

  Wang, Wei ^a   Basinger, Alice ^a   Neese, Richard A ^a   Christiansen, Mark ^a   Hellerstein, Marc K ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Gluconeogenesis; Glycogenolysis; Lipolysis; Mass isotopomer distribution analysis; Randle cycle

Indexed keywords

FATTY ACID; FUEL; GLUCOSE; NICOTINIC ACID;

ADULT; ARTICLE; BASAL METABOLIC RATE; CONTROLLED STUDY; FATTY ACID BLOOD LEVEL; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FEMALE; GLUCONEOGENESIS; GLUCOSE METABOLISM; GLYCOGENOLYSIS; HUMAN; HUMAN EXPERIMENT; LIPOLYSIS; MALE; NORMAL HUMAN; PRIORITY JOURNAL;

EID: 0033867890     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.2000.279.1.e50     Document Type: Article

References (45)

1. Influence of nicotinic acid on serum cholesterol in man
2. Influence of nicotinic acid on the rates of turnover and oxidation of plasma glucose in man
3. Operation of the glucose-fatty acid cycle after glycogenolysis induced by treatment with nicotinic acid
4. Acute lowering of plasma fatty acids lowers basal insulin secretion in diabetic and nondiabetic subjects
5. Mechanisms of fatty acid-induced inhibition of glucose uptake
6. Effects of lipid on basal carbohydrate metabolism in normal men
7. Fifteen year mortality in Coronary Drug Project patients: Long-term benefit with niacin
8. Acute effects of nicotinic acid in the rat I. Plasma and liver lipids and blood glucose
9. The effect of nicotinic acid on the plasma free fatty acids. Demonstration of a metabolic type of sympathicolysis
10. The effects of free fatty acids on gluconeogenesis and glycogenolysis in normal subjects
11. The direct and indirect effects of insulin on hepatic glucose production in vivo
12. Gluconeogenesis (GNG) in NIDDM: Effects of energy restriction (Abstract)
13. Direct effects of catecholamines on hepatic glucose production in conscious dog are due to glycogenolysis
14. Glucose homeostasis in children with falciporum malaria: Precursor supply limits gluconeogenesis and glucose production
15. Use of niacin as a drug
16. Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans
17. Effect of nicotinic acid derivative on glucose levels and glucose tolerance in animal and in man
18. The theoretical bases of indirect calorimetry: A review
19. Role of fat-derived substrates in the regulation of gluconeogenesis during fasting
20. Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects
21. Nicotinic acid as therapy for dyslipidemia in non-insulin-dependent diabetes mellitus
22. The prevalence of side effects with regular and sustained-release nicotinic acid
23. Influence of nicotinic acid on metabolism of cholesterol and triglycerides in man
24. Effects of cigarette smoking and its cessation on lipid metabolism and energy expenditure in heavy smokers
25. Mass isotopomer distribution analysis: A technique for measuring biosynthesis and turnover of polymers
26. Mass isotopomer distribution analysis at eight years: Theoretical, analytic and experimental considerations
27. Hepatic gluconeogenic fluxes and glycogen turnover during fasting in humans. A stable isotope study
28. Basal fuel homoeostasis in symptomatic human immunodeficiency virus infection
29. Effect of nicotinic acid on plasma glucose concentration in normal individuals
30. The effect of acute glucagon removal on the metabolic response to stress hormone infusion in the conscious dog
31. Glucose tolerance and plasma insulin in man during acute and chronic administration of nicotinic acid
32. Gluconeogenesis and intrahepatic triose phosphate flux in response to fasting or substrate loads. Application of the mass isotopomer distribution analysis technique with testing of assumptions and potential problems
33. 13C]glycerol and mass isotopomer distribution analysis of glucose
34. Biphasic nature of blood glucose and free fatty acid changes following intravenous nicotinic acid in man
35. Limitations of the mass isotopomer distribution analysis of glucose to study gluconeogenesis. Substrate cycling between glycerol and triose phosphates in liver
36. The glucose-fatty acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
37. 13C NMR
38. Short-term alterations in carbohydrate energy intake in humans. Striking effects on hepatic glucose production, de novo lipogenesis, lipolysis, and whole-body fuel selection
39. 1]glycerol
40. Studies on the effects of nicotinic acid given orally or intravenously on oral and intravenous glucose tolerance in man
41. Uptake and release of glucose by the human kidney. Postabsorptive rates and responses to epinephrine
42. Gluconeogenesis in very low birth weight infants receiving total parenteral nutrition
43. Action of the oral hypoglycemic agent 2-tetradecylglycidic acid on hepatic fatty acid oxidation and gluconeogenesis
44. Effect of severe burn injury on substrate cycling by glucose and fatty acids