Borrelidin, a potent antimalarial: Stage-specific inhibition profile of synchronized cultures of Plasmodium falciparum

Journal of Antibiotics

Volumn 64, Issue 5, 2011, Pages 381-384

  Ishiyama, Aki ^a   Iwatsuki, Masato ^a   Namatame, Miyuki ^a   Nishihara Tsukashima, Aki ^a   Sunazuka, Toshiaki ^a   Takahashi, Yoko ^a   Ömura, Satoshi ^a   Otoguro, Kazuhiko ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

antibiotics; artemisinin; borrelidin; microbial metabolites; Plasmodium falciparum; synchronous culture

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE; AZITHROMYCIN; BORRELIDIN; CHLOROQUINE; CYCLIN DEPENDENT KINASE; HALOFANTRINE; MEFLOQUINE; OM 0060; PYRIMETHAMINE PLUS SULFADOXINE; QUININE; THREONINE; THREONINE TRANSFER RNA LIGASE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SAFETY; ENZYME ACTIVITY; ENZYME INHIBITION; FUNGAL STRAIN; GROWTH INHIBITION; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALARIA; NONHUMAN; NUCLEAR DIVISION; PARASITE DEVELOPMENT; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; SCHIZONT; TROPHOZOITE; VIRUS REPLICATION; WORLD HEALTH ORGANIZATION;

ANTIMALARIALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; FATTY ALCOHOLS; L-LACTATE DEHYDROGENASE; PLASMODIUM FALCIPARUM; TROPHOZOITES;

PLASMODIUM FALCIPARUM;

EID: 79957618355     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2011.6     Document Type: Article

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