In vitro and in vivo antimalarial activities of the monoglycoside polyether antibiotic, K-41 against drug resistant strains of Plasmodia [2]

Journal of Antibiotics

Volumn 55, Issue 9, 2002, Pages 832-834

  Otoguro, Kazuhiko ^a   Ishiyama, Aki ^a   Ui, Hideaki ^a   Kobayashi, Miyuki ^a   Manabe, Chizu ^a   Yan, Guan ^a   Takahashi, Yoko ^a   Tanaka, Haruo ^a   Yamada, Haruki ^a   Omura, Satoshi ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5 BROMO LOSALOCID A; ANTIMALARIAL AGENT; ARTEMETHER; ARTEMISIN; ARTESUNATE; CHLOROQUINE; COCCIDIOSTATIC AGENT; K 41; LOSALOCID A; MONENSIN A; PYRIMETHAMINE; SALINOMYCIN; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ANTIMALARIAL ACTIVITY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG PURIFICATION; DRUG SELECTIVITY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; LETTER; MALARIA; MOUSE; NONHUMAN; PLASMODIUM; PRIORITY JOURNAL;

EID: 0036748252     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.55.832     Document Type: Letter

References (7)

1. Otoguro, K.; A. Kohana, C. Manabe, A. Ishiyama, H. Ui, K. Siomi, H. Yamada & S. OmurA: Potent antimalarial activities of polyether antibiotic, X-206. J. Antibiotics 54: 658-663, 2001
2. Tsuji, N.; K. Nagashima, M. Kobayashi, Y. Wakisaka, Y. Kawamura, S. Kozuki & M. Mayama: Two new antibiotics, A-218 and K-41 isolation and characterization. J. Antibiotics 29: 10-4, 1976
3. Peters, W.; J. H. Portus & B. L. Robinson: The chemotherapy of rodent malaria. XXII. The value of drug-resistant strains of P. berghei in screening for blood schizonticidal activity. Ann. Trop. Med. Parasitol. 69: 155-171, 1975
4. Bérdy, J.: Polyether antibiotics. In CRC Handbook of Antibiotic Compounds. Volume V. pp. 461-465, CRC Press, Inc. Boca Raton, Florida, 1981
5. Raether, W.; H. Seidenath, H. Mehlhorn & H. J. Ganster: The action of salinomycin-Na and lasalocid-Na on chloroquine- and mepacrine-resistant line of Plasmodium berghei K 173-strain in Wistar rats, Z. Parasitenkd. 71: 567-74, 1985
6. Schildknecht, E. G.; D. Siegel & R. W. Richle: Antiparasitic activity of natural and semisynthetic monensin urethanes. Chemotherapy (Basel) 29: 145-152, 1983
7. Gumila, C.; M. L. Ancelin, A. M. Delort, G. Jeminet, A. M. Delort & H. J. Vial: Characterization of the potent in vitro and in vivo antimalarial activities of ionophore compounds. Antimicrob. Agents Chemother. 41: 523-529, 1996