KSR Plays CRAF-ty

Science

Volumn 332, Issue 6033, 2011, Pages 1043-1044

  Shi, Fumin ^a   Lemmon, Mark A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; KINASE SUPPRESSOR OF RAS; MITOGEN ACTIVATED PROTEIN KINASE; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; KSR 1 PROTEIN KINASE; KSR-1 PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN KINASE; RAF PROTEIN;

BIOCHEMISTRY; ENZYME ACTIVITY; MOLECULAR ANALYSIS; PROTEIN;

ENZYME ACTIVITY; GENOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SHORT SURVEY; ALLOSTERISM; ANIMAL; ARTICLE; BINDING SITE; CELL MEMBRANE; CHEMISTRY; DRUG ANTAGONISM; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MUTATION; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION;

ALLOSTERIC REGULATION; ANIMALS; BINDING SITES; CATALYTIC DOMAIN; CELL MEMBRANE; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MUTATION; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN KINASES; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS C-RAF;

EID: 79957615188     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1208063     Document Type: Short Survey

References (15)

1. M. C. Good, J. G. Zalatan, W. A. Lim, Science 332, 680 (2011).
2. D. F. Brennan et al., Nature 472, 366 (2011).
3. J. Hu et al., Proc. Natl. Acad. Sci. U.S.A. 108, 6067 (2011).
4. M. M. McKay, D. A. Ritt, D. K. Morrison, Curr. Biol. 21, 563 (2011).
5. W. Kolch, Nat. Rev. Mol. Cell Biol. 6, 827 (2005).
6. D. K. Morrison, J. Cell Sci. 114, 1609 (2001).
7. M. M. McKay, D. A. Ritt, D. K. Morrison, Proc. Natl. Acad. Sci. U.S.A. 106, 11022 (2009).
8. G. Bollag et al., Nature 467, 596 (2010).
9. P. I. Poulikakos, N. Rosen, Cancer Cell 19, 11 (2011).
10. C. M. Udell, T. Rajakulendran, F. Sicheri, M. Therrien, Cell. Mol. Life Sci. 68, 553 (2011).
11. E. Zeqiraj, D. M. van Aalten, Curr. Opin. Struct. Biol. 20, 772 (2010).
12. T. Rajakulendran, M. Sahmi, M. Lefrançois, F. Sicheri, M. Therrien, Nature 461, 542 (2009).
13. K. Cichowski, P. A. Jänne, Nature 464, 358 (2010).
14. K. Mukherjee et al., Cell 133, 328 (2008).
15. F. Shi, S. E. Telesco, Y. Liu, R. Radhakrishnan, M. A. Lemmon, Proc. Natl. Acad. Sci. U.S.A. 107, 7692 (2010).