Formation of stable homomeric and transient heteromeric bone morphogenetic protein (BMP) receptor complexes regulates smad protein signaling

Journal of Biological Chemistry

Volumn 286, Issue 22, 2011, Pages 19287-19296

  Marom, Barak ^a   Heining, Eva ^b   Knaus, Petra ^b   Henis, Yoav I ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BMP RECEPTORS; BMPR-IB; BONE MORPHOGENETIC PROTEINS; CELL SURFACES; EXTRACELLULAR DOMAINS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; HETEROCOMPLEXES; HETEROMERIC COMPLEXES; HETEROTETRAMERS; HOMODIMERIZATION; HOMODIMERS; LATERAL DIFFUSION; LIGAND BINDING; PLASMA MEMBRANES; PROTEIN SIGNALING; RECEPTOR COMPLEX; STEADY-STATE LEVEL; TIME-SCALES; TYPE II;

BONE; CELL MEMBRANES; COMPETITION; CYTOLOGY; ENZYME ACTIVITY; LIGANDS; OLIGOMERS; PHOSPHORYLATION; PHOTOBLEACHING; PROTEINS; SIGNALING;

COMPLEXATION;

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTOR; BONE MORPHOGENETIC PROTEIN RECEPTOR 1; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; EPITOPE; IMMUNOGLOBULIN G; LIGAND; MONOMER; OLIGOMER; SMAD PROTEIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL SURFACE; COMPLEX FORMATION; CONTROLLED STUDY; DIFFUSION; DIMERIZATION; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STEADY STATE;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; CERCOPITHECUS AETHIOPS; COS CELLS; HUMANS; MULTIENZYME COMPLEXES; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION; SMAD PROTEINS;

EID: 79957610793     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.210377     Document Type: Article

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