An optimized pentaplex PCR for detecting DNA mismatch repair-deficient colorectal cancers

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Goel, Ajay ^a   Nagasaka, Takeshi ^a   Hamelin, Richard ^b   Boland, C Richard ^a  

^a BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; COLORECTAL CANCER; FAMILIAL CANCER; GENE AMPLIFICATION; HUMAN; IMMUNOHISTOCHEMISTRY; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MULTIPLEX POLYMERASE CHAIN REACTION; NUCLEOTIDE REPEAT; POLYMERASE CHAIN REACTION; PREDICTION; QUASI EXPERIMENTAL STUDY; ADULT; COHORT ANALYSIS; COLORECTAL TUMOR; FEMALE; GENE FREQUENCY; GENETICS; GENOTYPE; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; MUTATION; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

ADENOSINE TRIPHOSPHATASE; DNA BINDING PROTEIN; G T MISMATCH BINDING PROTEIN; G-T MISMATCH-BINDING PROTEIN; MLH1 PROTEIN, HUMAN; MSH2 PROTEIN, HUMAN; NUCLEAR PROTEIN; PMS2 PROTEIN, HUMAN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN MSH2; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR MARKER;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATASES; ADULT; ALLELES; COHORT STUDIES; COLORECTAL NEOPLASMS; DNA MISMATCH REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL;

EID: 77949721693     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009393     Document Type: Article

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