Neonatal exposure to herbicide acetochlor alters pubertal development in female wistar rats

Toxicology Mechanisms and Methods

Volumn 21, Issue 5, 2011, Pages 406-417

  Rollerova, Eva ^a   Wsolova, Ladislava ^a   Urbancikova, Miroslava ^a  

^a SLOVAK MEDICAL UNIVERSITY   (Slovakia)

Author keywords

endocrine disruptors; estrogen receptor; estrous cycle; Herbicides; reproductive toxicity

Indexed keywords

ACETOCHLOR; ESTRADIOL; ESTROGEN RECEPTOR;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING ASSAY; CONTROLLED STUDY; ESTRUS CYCLE; EX VIVO STUDY; FEMALE; GROWTH ACCELERATION; HORMONE BINDING; NONHUMAN; OVARIECTOMY; PERINATAL DRUG EXPOSURE; PRIORITY JOURNAL; PUBERTY; REPRODUCTION; UTERUS WEIGHT;

ANIMALS; ANIMALS, NEWBORN; CELL NUCLEUS; CYTOPLASM; ENDOCRINE DISRUPTORS; ESTRADIOL; EYE; FEMALE; HERBICIDES; INJECTIONS, SUBCUTANEOUS; PROTEIN BINDING; PUBERTY; RATS; RATS, WISTAR; RECEPTORS, ESTROGEN; SEXUAL MATURATION; TOLUIDINES; UTERUS; VAGINA;

RATTUS; RATTUS NORVEGICUS;

EID: 79957506677     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.3109/15376516.2010.551554     Document Type: Article

References (69)

1. Acosta-Martinez M, Horton T, Levine JE. 2007. Estrogen receptors in neuropeptide Y neurons: at the crossroads of feeding and reproduction. Trends Endocrinol Metab 18:48-50. (Pubitemid 46275456)
2. Alexandrova M, Soloff MS. 1980. Oxytocin receptors and parturition. I. Control of oxytocin receptor concentration in the rat myometrium at term. Endocrinology 106:730-735. (Pubitemid 10135101)
3. Anderson J, Clark JH, Peck EJ Jr. 1972. Oestrogen and nuclear binding sites. Determination of specific sites by (3 H)oestradiol exchange. Biochem J 126:561-567.
4. Arcury TA, Grzywacz JG, Barr DB, Tapia J, Chen H, Quandt SA. 2007. Pesticide urinary metabolite levels of children in eastern North Carolina farmworker households. Environ Health Perspect 115:1254-1260. (Pubitemid 351802361)
5. Ashby J, Kier L, Wilson AG, Green T, Lefevre PA, Tinwell H, Willis GA, Heydens WF, Clapp MJ. 1996. Evaluation of the potential carcinogenicity and genetic toxicity to humans of the herbicide acetochlor. Hum Exp Toxicol 15:702-735. (Pubitemid 26331687)
6. Ashby J, Tinwell H, Haseman J. 1999. Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero. Regul Toxicol Pharmacol 30:156-166.
7. Baligar PN, Kaliwal BB. 2004. Carbofuran induced block of compensatory ovarian growth in hemicastrated albino mice. Toxicology 204:87-95. (Pubitemid 39244070)
8. Balinova AM. 1997. Acetochlor-a comparative study on parameters governing the potential for water pollution. J Environ Sci Health B 32:645-658. (Pubitemid 27385584)
9. Barr DB, Hines CJ, Olsson AO, Deddens JA, Bravo R, Striley CA, Norrgran J, Needham LL. 2007. Identification of human urinary metabolites of acetochlor in exposed herbicide applicators by high-performance liquid chromatography- tandem mass spectrometry. J Expo Sci Environ Epidemiol 17:559-566. (Pubitemid 47414392)
10. BenesováO, TejkalováH, KristofikováZ, Panajotova V, Husek P. 1999. Neuroimmuno- teratogenicity of drugs used in neonatal pharmacotherapy in relation to the ontogenic stage at the time of their administration. Gen Physiol Biophys 18 Spec No:21-27.
11. Buck Louis GM, Lynch CD, Cooney MA. 2006. Environmental influences on female fecundity and fertility. Semin Reprod Med 24:147-155.
12. Burroughs CD, Bern HA, Stokstad EL. 1985. Prolonged vaginal cornification and other changes in mice treated neonatally with coumestrol, a plant estrogen. J Toxicol Environ Health 15:51-61. (Pubitemid 15092006)
13. Cheek AO, Kow K, Chen J, McLachlan JA. 1999. Potential mechanisms of thyroid disruption in humans: interaction of organochlorine compounds with thyroid receptor, transthyretin, and thyroid-binding globulin. Environ Health Perspect 107:273-278. (Pubitemid 29231629)
14. Clark JH, Anderson JN, Peck EJ Jr. 1973. Estrogen receptor-anti-estrogen complex: atypical binding by uterine nuclei and effects on uterine growth. Steroids 22:707-718.
15. Coleman S, Linderman R, Hodgson E, Rose RL. 2000. Comparative metabolism of chloroacetamide herbicides and selected metabolites in human and rat liver microsomes. Environ Health Perspect 108:1151-1157. (Pubitemid 32049100)
16. Cooper RL, Goldman JM. (1999). VI. Vaginal cytology. In: Daston G, Kimmel C, ed. An Evaluation and Interpretation of Reproductive Endpoints for Human Health Risk Assessment. Washington DC: ILSI Press, pp. 42-56.
17. Crump D, Werry K, Veldhoen N, Van Aggelen G, Helbing CC. 2002. Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis. Environ Health Perspect 110:1199-1205. (Pubitemid 36024303)
18. David MB, Gentry LE, Starks KM, Cooke RA. 2003. Stream transport of herbicides and metabolites in a tile-drained, agricultural watershed. J Environ Qual 32:1790-1801. (Pubitemid 37174232)
19. Delclos KB, Weis CC, Bucci TJ, Olson G, Mellick P, Sadovova N, Latendresse JR, Thorn B, Newbold RR. 2009. Overlapping but distinct effects of genistein and ethinyl estradiol (EE(2)) in female Sprague-Dawley rats in multigenerational reproductive and chronic toxicity studies. Reprod Toxicol 27:117-132.
20. Dickerson SM, Gore AC. 2007. Estrogenic environmental endocrine-disrupting chemical effects on reproductive neuroendocrine function and dysfunction across the life cycle. Rev Endocr Metab Disord 8:143-159. (Pubitemid 47434648)
21. Eriksson HA. 1982. Different regulation of the concentration of estrogen receptors in the rat liver and uterus following ovariectomy. FEBS Lett 149:91-95. (Pubitemid 13177104)
22. Faass O, Schlumpf M, Reolon S, Henseler M, Maerkel K, Durrer S, Lichtensteiger W. 2009. Female sexual behavior, estrous cycle and gene expression in sexually dimorphic brain regions after pre- and postnatal exposure to endocrine active UV filters. Neurotoxicology 30:249-260.
23. Fernández M, Bianchi M, Lux-Lantos V, Libertun C. 2009. Neonatal exposure to bisphenol a alters reproductive parameters and gonadotropin releasing hormone signaling in female rats. Environ Health Perspect 117:757-762.
24. Freeman JL, Rayburn AL. 2006. Aquatic herbicides and herbicide contaminants: In vitro cytotoxicity and cell-cycle analysis. Environ Toxicol 21:256-263. (Pubitemid 43765061)
25. Giknis MLA, Clifford ChB. 2009. Reproductive parameters and fetal data from reproductive toxicity studies in the Charles River Wistar Hannover [Crl:WI(Han)] rat. Available at: http://www.criver.com/ SiteCollectionDocuments/ rm-rm-r-Wistar-Han-reproductive-tox- studies-09.pdf
26. Goldman JM, Laws SC, Balchak SK, Cooper RL, Kavlock RJ. 2000. Endocrinedisrupting chemicals: prepubertal exposures and effects on sexual maturation and thyroid activity in the female rat. A focus on the EDSTAC recommendations. Crit Rev Toxicol 30:135-196. (Pubitemid 30193746)
27. Goldman JM, Murr AS, Cooper RL. 2007. The rodent estrous cycle: characterization of vaginal cytology and its utility in toxicological studies. Birth Defects Res B Dev Reprod Toxicol 80:84-97. (Pubitemid 46762318)
28. Gore AC. 2008. Developmental programming and endocrine disruptor effects on reproductive neuroendocrine systems. Front Neuroendocrinol 29:358-374.
29. Gould JC, Leonard LS, Maness SC, Wagner BL, Conner K, Zacharewski T, Safe S, McDonnell DP, Gaido KW. 1998. Bisphenol A interacts with the estrogen receptor alpha in a distinct manner from estradiol. Mol Cell Endocrinol 142:203-214. (Pubitemid 28438292)
30. Green T, Lee R, Moore RB, Ashby J, Willis GA, Lund VJ, Clapp MJ. 2000. Acetochlor-induced rat nasal tumors: further studies on the mode of action and relevance to humans. Regul Toxicol Pharmacol 32:127-133.
31. Hany J, Lilienthal H, Sarasin A, Roth-Härer A, Fastabend A, Dunemann L, Lichtensteiger W, Winneke G. 1999. Developmental exposure of rats to a reconstituted PCB mixture or aroclor 1254: effects on organ weights, aromatase activity, sex hormone levels, and sweet preference behavior. Toxicol Appl Pharmacol 158:231-243. (Pubitemid 29382941)
32. Hazardous Substances Databank and the National Library of Medicine's TOXNET System. 2002. Available at: http://www.toxnet.nlm.nih.gov
33. Hill AB, Jefferies PR, Quistad GB, Casida JE. 1997. Dialkylquinoneimine metabolites of chloroacetanilide herbicides induce sister chromatid exchanges in cultured human lymphocytes. Mutat Res 395:159-171. (Pubitemid 28022546)
34. Hiller E, Krascsenits Z, Cernanský S. 2008. Sorption of acetochlor, atrazine, 2,4-D, chlorotoluron, MCPA, and trifluralin in six soils from Slovakia. Bull Environ Contam Toxicol 80:412-416.
35. Hurley PM. 1998. Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents. Environ Health Perspect 106:437-445. (Pubitemid 28470158)
36. Integrated Risk Information System. 2007. Acetochlor (CASRN 34256-82-1). Available at: http://www.epa.gov/ncea/iris/subst/0521.htm
37. Kale VM, Miranda SR, Wilbanks MS, Meyer SA. 2008. Comparative cytotoxicity of alachlor, acetochlor, and metolachlor herbicides in isolated rat and cryopreserved human hepatocytes. J Biochem Mol Toxicol 22:41-50. (Pubitemid 351360161)
38. Katsuda S, Yoshida M, Watanabe G, Taya K, Maekawa A. 2000. Irreversible effects of neonatal exposure to p-tert-octylphenol on the reproductive tract in female rats. Toxicol Appl Pharmacol 165:217-226. (Pubitemid 30429905)
39. Khalkova Zh, Zaikov Kh, Buzidi A, Antov G. 1990. [Biochemical changes in the brain tissue of white rats exposed to the herbicide acetochlor under acute and subacute oral experimental conditions]. Probl Khig 15:96-102.
40. Kim HS, Shin JH, Moon HJ, Kang IH, Kim TS, Kim IY, Seok JH, Pyo MY, Han SY. 2002. Comparative estrogenic effects of p-nonylphenol by 3-day uterotrophic assay and female pubertal onset assay. Reprod Toxicol 16:259-268. (Pubitemid 34966264)
41. Konda LN, Pásztor Z. 2001. Environmental distribution of acetochlor, atrazine, chlorpyrifos, and propisochlor under field conditions. J Agric Food Chem 49:3859-3863. (Pubitemid 32822707)
42. Kovriznych J, Urbancikova M. 1998. Acute toxicity of acetochlor for zebrafish (Danio rerio) and guppy (Poecilia reticulata). Ecol (Bratislava) 17:449-456. (Pubitemid 29130795)
43. Kouki T, Okamoto M, Wada S, Kishitake M, Yamanouchi K. 2005. Suppressive effect of neonatal treatment with a phytoestrogen, coumestrol, on lordosis and estrous cycle in female rats. Brain Res Bull 64:449-454. (Pubitemid 39656125)
44. Kupfer D, Bulger WH. 1976. Studies on the mechanism of estrogenic actions of o, p'-DDT: Interaction with estrogen receptor. Pesticide Biochem Physiol 6:561-570. (Pubitemid 8003352)
45. Laws SC, Carey SA, Ferrell JM, Bodman GJ, Cooper RL. 2000. Estrogenic activity of octylphenol, nonylphenol, bisphenol A and methoxychlor in rats. Toxicol Sci 54:154-167. (Pubitemid 30152466)
46. Lengyel Z, Földényi R. 2003. Acetochlor as a soil pollutant. Environ Sci Pollut Res Int 10:13-18. (Pubitemid 36251470)
47. Lind PM, Eriksen EF, Sahlin L, Edlund M, Orberg J. 1999. Effects of the antiestrogenic environmental pollutant 3,3',4,4', 5-pentachlorobiphenyl (PCB #126) in rat bone and uterus: diverging effects in ovariectomized and intact animals. Toxicol Appl Pharmacol 154:236-244. (Pubitemid 29085235)
48. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275.
49. Mackenzie PI, Rodbourne L, Stranks S. 1992. Steroid UDP glucuronosyltransferases. J Sterod Biochem Mol Biol 43:1099-1105. (Pubitemid 23044726)
50. Marty MS, Crissman JW, Carney EW. 1999. Evaluation of the EDSTAC female pubertal assay in CD rats using 17beta-estradiol, steroid biosynthesis inhibitors, and a thyroid inhibitor. Toxicol Sci 52:269-277. (Pubitemid 30017603)
51. Mendoza-Rodríguez CA, García-Guzmán M, Baranda-Avila N, Morimoto S, Perrot-Applanat M, Cerbón M. 2010. Administration of bisphenol A to dams during perinatal periods modifies molecular and morphological reproductive parameters of the offspring. Reprod Toxicol, doi: 10.1016/j. reprotox.2010.10.013
52. Newcombe AC, Gustafson DI, Fuhrman JD, van Wesenbeeck IJ, Simmons ND, Klein AJ, Travis KZ, Harradine KJ. 2005. The acetochlor registration partnership: prospective ground water monitoring program. J Environ Qual 34:1004-1015. (Pubitemid 40677239)
53. Odum J, Lefevre PA, Tinwell H, Van Miller JP, Joiner RL, Chapin RE, Wallis NT, Ashby J. 2002. Comparison of the developmental and reproductive toxicity of diethylstilbestrol administered to rats in utero, lactationally, preweaning, or postweaning. Toxicol Sci 68:147-163. (Pubitemid 34785237)
54. Oosterhuis B, Vukman K, Vági E, Glavinas H, Jablonkai I, Krajcsi P. 2008. Specific interactions of chloroacetanilide herbicides with human ABC transporter proteins. Toxicology 248:45-51.
55. RollerováE, GáspárováZ, Wsólová L, UrbancíkováM. 2000. Interaction of acetochlor with estrogen receptor in the rat uterus. Acetochlor-possible endocrine modulator? Gen Physiol Biophys 19:73-84. (Pubitemid 30415167)
56. Rubin BS, Murray MK, Damassa DA, King JC, Soto AM. 2001. Perinatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels. Environ Health Perspect 109:675-680. (Pubitemid 32785423)
57. Sahlin L, Eriksson H. 1996. Influence of blockers for the estrogen receptor (ER) and type 1 IGF-receptor on the levels of ER, ER mRNA and IGF-I mRNA in the rat uterus. J Steroid Biochem Mol Biol 58:359-365. (Pubitemid 26348969)
58. Scatchard G. 1949. The attraction of proteins for small molecules and ions. Ann NY Acad Sci 51:660-672.
59. Schoeters G, Den Hond E, Dhooge W, van Larebeke N, Leijs M. 2008. Endocrine disruptors and abnormalities of pubertal development. Basic Clin Pharmacol Toxicol 102:168-175. (Pubitemid 351143431)
60. Terasawa E, Fernandez DL. 2001. Neurobiological mechanisms of the onset of puberty in primates. Endocr Rev 22:111-151. (Pubitemid 32187805)
61. Turque N, Palmier K, Le Mével S, Alliot C, Demeneix BA. 2005. A rapid, physiologic protocol for testing transcriptional effects of thyroid-disrupting agents in premetamorphic Xenopus tadpoles. Environ Health Perspect 113:1588-1593. (Pubitemid 41614916)
62. US EPA. 1994. Acetochlor registration agreement and addendums (Docket ID EPA-HQ-OPP-2007-0725). Washington DC: US EPA.
63. US EPA. 2007. Integrated summary report for validation of a test method for assessment of pubertal development and thyroid function in juvenile female rats as a potential screen in the Endocrine disruptor screening program Tier-1 battery. Available at: www.epa.gov/endo/pubs/female- isr-v4.1c.pdf
64. US EPA. 2009. Federal Register Environmental Documents. Acetochlor, Pesticide Tolerances. Available at: http://www.epa.gov/EPA-PEST/2009/ September/Day-16/p21845.htm
65. Wester RC, Melendres JL, Maibach HI. 1996. In vivo percutaneous absorption of acetochlor in the rhesus monkey: dose-response and exposure risk assessment. Food Chem Toxicol 34:979-983. (Pubitemid 27036780)
66. Yoshida M, Katsuda S, Ando J, Kuroda H, Takahashi M, Maekawa A. 2000. Subcutaneous treatment of p-tert-octylphenol exerts estrogenic activity on the female reproductive tract in normal cycling rats of two different strains. Toxicol Lett 116:89-101. (Pubitemid 30440771)
67. Zacharewski TR, Meek MD, Clemons JH, Wu ZF, Fielden MR, Matthews JB. 1998. Examination of the in vitro and in vivo estrogenic activities of eight commercial phthalate esters. Toxicol Sci 46: 282-293. (Pubitemid 29069612)
68. Zava DT, Harrington NY, McGuire WL. 1976. Nuclear estradiol receptor in the adult rat uterus: a new exchange assay. Biochemistry 15:4292-4297.
69. Zbinden G. 1981. Experimental methods in behavioral teratology. Arch Toxicol 48:69-88. (Pubitemid 11055907)