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Volumn 16, Issue 4, 2011, Pages 334-345

A quantitative approach to evaluate urinary benzene and S-phenylmercapturic acid as biomarkers of low benzene exposure

Author keywords

chemical carcinogenesis; Environmental pollution Ecotoxicology; mass spectroscopy

Indexed keywords

BENZENE; BIOLOGICAL MARKER; COTININE; CREATININE; N ACETYL S PHENYLCYSTEINE; UNCLASSIFIED DRUG;

EID: 79957494975     PISSN: 1354750X     EISSN: 13665804     Source Type: Journal    
DOI: 10.3109/1354750X.2011.561499     Document Type: Article
Times cited : (29)

References (57)
  • 1
    • 79957500672 scopus 로고    scopus 로고
    • TLVs and BEIs based on the documentation of the threshold limit values for chemical substances and physical agents and biological indices
    • American Conference of Governmental Industrial Hygienists (ACGIH),USA: ACGIH
    • American Conference of Governmental Industrial Hygienists (ACGIH)(2009). TLVs and BEIs based on the documentation of the threshold limit values for chemical substances and physical agents and biological indices. Cincinnati, USA: ACGIH.
    • (2009) Cincinnati
  • 2
    • 0032802583 scopus 로고    scopus 로고
    • Solid-phase microextraction and gas chromatography-mass spectrometry for determination of monoaromatic hydrocarbons in blood and urine: Application to people exposed to air pollutants
    • DOI 10.1007/BF02490647
    • Andreoli R, Manini P, Bergamaschi E, Brustolin A, Mutti A. (1999). Solid-phase microextraction and gas chromatography-mass spectrometry for determination of monoaromatic hydrocarbons in blood and urine: application to people exposed to air pollutants. Chromatographia 20:167-72. (Pubitemid 29398414)
    • (1999) Chromatographia , vol.50 , Issue.3-4 , pp. 167-172
    • Andreoli, R.1    Manini, P.2    Bergamaschi, E.3    Brustolin, A.4    Mutti, A.5
  • 3
    • 0036230540 scopus 로고    scopus 로고
    • Development and validation of a competitive immunoassay for urinary S-phenylmercapturic acid and its application in benzene biological monitoring
    • DOI 10.1080/13547500110099663
    • Aston JP, Ball RL, Pople JE, Jones K, Cocker J. (2002). Development and validation of a competitive immunoassay for urinary S-phenylmercapturic acid and its application in benzene biological monitoring. Biomarkers 7:103-112. (Pubitemid 34413860)
    • (2002) Biomarkers , vol.7 , Issue.2 , pp. 103-112
    • Aston, J.P.1    Ball, R.L.2    Pople, J.E.3    Jones, K.4    Cocker, J.5
  • 4
    • 21244465964 scopus 로고    scopus 로고
    • Handling of dioxin measurement data in the presence of non-detectable values: Overview of available methods and their application in the Seveso chloracne study
    • DOI 10.1016/j.chemosphere.2005.01.055, PII S0045653505002006
    • Baccarelli A, Pfeiffer R, Consonni D, Pesatori AC, Bonzini M, Patterson DG Jr, Bertazzi PA, Landi MT. (2005). Handling of dioxin measurement data in the presence of non-detectable values: overview of available methods and their application in the Seveso chloracne study Chemosphere 60:898-906 (Pubitemid 40898138)
    • (2005) Chemosphere , vol.60 , Issue.7 , pp. 898-906
    • Baccarelli, A.1    Pfeiffer, R.2    Consonni, D.3    Pesatori, A.C.4    Bonzini, M.5    Patterson Jr., D.G.6    Bertazzi, P.A.7    Landi, M.T.8
  • 5
    • 55649100958 scopus 로고    scopus 로고
    • Urinary biomarkers and low-level environmental benzene concentration: Assessing occupational and general exposure
    • Barbieri A, Violante FS, Sabatini L, Graziosi F, Mattioli S. (2008). Urinary biomarkers and low-level environmental benzene concentration: assessing occupational and general exposure. Chemosphere 74:64-69.
    • (2008) Chemosphere , vol.74 , pp. 64-69
    • Barbieri, A.1    Violante, F.S.2    Sabatini, L.3    Graziosi, F.4    Mattioli, S.5
  • 6
    • 14744271278 scopus 로고    scopus 로고
    • Urinary creatinine concentrations in the U.S. population: Implications for urinary biologic monitoring measurements
    • DOI 10.1289/ehp.7337
    • Barr DB, Wilder LC, Caudill SP, Gonzalez AJ, Needham LL, Pirkle JL. (2005). Urinary creatinine concentrations in the U.S. population: implications for urinary biologic monitoring measurements. Environ Health Perspect 113:192-200. (Pubitemid 40326330)
    • (2005) Environmental Health Perspectives , vol.113 , Issue.2 , pp. 192-200
    • Barr, D.B.1    Wilder, L.C.2    Caudill, S.P.3    Gonzalez, A.J.4    Needham, L.L.5    Pirkle, J.L.6
  • 7
    • 0029081877 scopus 로고
    • Biological monitoring of exposure to benzene: A comparison between S-phenylmercapturic acid, trans-trans-muconic acid, and phenol
    • Boogaard PJ, van Sittert NJ. (1995). Biological monitoring of exposure to benzene: a comparison between S-phenylmercapturic acid, trans-trans-muconic acid, and phenol. Occup Environ Health 52:611-20.
    • (1995) Occup Environ Health , vol.52 , pp. 611-20
    • Boogaard, P.J.1    Van Sittert, N.J.2
  • 10
    • 33645345747 scopus 로고    scopus 로고
    • List of MAK and BAT values 2009
    • Deutsch Forschungsgemeinschaft (DFG),Weinheim: DFG, WILEY -VCH
    • Deutsch Forschungsgemeinschaft (DFG). (2009). List of MAK and BAT values 2009. Report No 40, Weinheim: DFG, WILEY-VCH.
    • (2009) Report No 40
  • 11
    • 0032953636 scopus 로고    scopus 로고
    • Validity of biomarkers in environmental health studies: The case of PAHs and Benzene
    • Dor F, Dab W, Empereur-Bissonnet P, Zmirou D. (1999). Validity of biomarkers in environmental health studies: the case of PAHs and benzene. Crit Rev Toxicol 29:129-168. (Pubitemid 29169594)
    • (1999) Critical Reviews in Toxicology , vol.29 , Issue.2 , pp. 129-168
    • Dor, F.1    Dab, W.2    Empereur-Bissonnet, P.3    Zmirou, D.4
  • 13
    • 79957448495 scopus 로고    scopus 로고
    • The european environmental & health and action plan 2004-2010
    • European Commission. Communication from the Commission to the Council, the European Parliament, the European Economic and Social Committee.,Brussels, Belgium
    • European Commission. (2004). Communication from the Commission to the Council, the European Parliament, the European Economic and Social Committee. "The European Environmental & Health and Action Plan 2004-2010" SEC (2004) 729. Brussels, Belgium.
    • (2004) SEC (2004) , pp. 729
  • 17
    • 0029063282 scopus 로고
    • Biological and environmental monitoring of exposure to airborne benzene and other aromatic hydrocarbons in Milan traffic wardens
    • Fustinoni S, Buratti M, Giampiccolo R, Colombi A. (1995). Biological and environmental monitoring of exposure to airborne benzene and other aromatic hydrocarbons in Milan traffic wardens. Toxicol Lett 77:387-392.
    • (1995) Toxicol Lett , vol.77 , pp. 387-392
    • Fustinoni, S.1    Buratti, M.2    Giampiccolo, R.3    Colombi, A.4
  • 18
    • 77952551428 scopus 로고    scopus 로고
    • Urinary BTEX,MTBE and naphthalene as biomarkers to gain environmental exposure profiles of the general population
    • Fustinoni S, Rossella F, Campo L, Mercadante R, Bertazzi PA. (2010a). Urinary BTEX, MTBE and naphthalene as biomarkers to gain environmental exposure profiles of the general population. Sci Total Environ 408:2840-2849.
    • (2010) Sci Total Environ , vol.408 , pp. 2840-2849
    • Fustinoni, S.1    Rossella, F.2    Campo, L.3    Mercadante, R.4    Bertazzi, P.A.5
  • 19
    • 77956872495 scopus 로고    scopus 로고
    • Methodological issues in biological monitoring of low exposures: The case of urinary benzene and S-phenylmercapturc acid
    • Fustinoni S, Campo L, Mercadante R, Manini P. (2010b). Methodological issues in biological monitoring of low exposures: the case of urinary benzene and S-phenylmercapturc acid. J Chromatogr B 878:2534-2540.
    • (2010) J Chromatogr B , vol.878 , pp. 2534-2540
    • Fustinoni, S.1    Campo, L.2    Mercadante, R.3    Manini, P.4
  • 27
    • 0034062557 scopus 로고    scopus 로고
    • Urinary phenylmercapturic acid as a marker of occupational exposure to benzene
    • Inoue O, Kanno E, Kakizaki M, Watanabe T, Higashikawa K, Ikeda M. (2000). Urinary phenylmercapturic acid as a marker of occupational exposure to benzene. Ind Health 38:195-204. (Pubitemid 30256985)
    • (2000) Industrial Health , vol.38 , Issue.2 , pp. 195-204
    • Inoue, O.1    Kanno, E.2    Kakizaki, M.3    Watanabe, T.4    Higashikawa, K.5    Ikeda, M.6
  • 28
    • 0034970873 scopus 로고    scopus 로고
    • A simple HPLC method to determine urinary phenylmercapturic acid and its application to gasoline station attendants to biomonitor occupational exposure to benzene at less than I ppm
    • DOI 10.1080/13547500010009582
    • Inoue O, Kanno E, Yusa T, Kakizaki M, Watanabe T, Higashikawa K, Ikeda M. (2001). A simple HPLC method to determine urinary phenylmercapturic acid and its application to gasoline station attendants to biomonitor occupational exposure to benzene at less than 1 ppm. Biomarkers 6:190-203. (Pubitemid 32547425)
    • (2001) Biomarkers , vol.6 , Issue.3 , pp. 190-203
    • Inoue, O.1    Kanno, E.2    Yusa, T.3    Kakizaki, M.4    Watanabe, T.5    Higashikawa, K.6    Ikeda, M.7
  • 31
    • 0027968513 scopus 로고
    • Blood and urinary benzene determined by headspace gas chromatography with photoionization detection: Application in biological monitoring of low-level nonoccupational exposure
    • Kok PW, Ong CN. (1994). Blood and urinary benzene determined by headspace gas chromatography with photoionization detection: application in biological monitoring of low-level nonoccupational exposure. Int Arch Occup Environ Health 66:195-201. (Pubitemid 24296535)
    • (1994) International Archives of Occupational and Environmental Health , vol.66 , Issue.3 , pp. 195-201
    • Kok, P.W.1    Ong, C.N.2
  • 32
    • 0022871434 scopus 로고
    • Automated determination of urinary creatinine without sample dilution: Theory and practice
    • Kroll MH, Chesler R, Hagengruber C, Blank DW, Kestner J, Rawe M. (1986). Automated determination of urinary creatinine without sample dilution: theory and practice. Clin Chem 32:446-452. (Pubitemid 17016958)
    • (1986) Clinical Chemistry , vol.32 , Issue.3 , pp. 446-452
    • Kroll, M.H.1    Chesler, R.2    Hagengruber, C.3
  • 34
    • 33745918301 scopus 로고    scopus 로고
    • Determination of S-phenylmercapturic acid in human urine using an automated sample extraction and fast liquid chromatography-tandem mass spectrometric method
    • DOI 10.1002/bmc.653
    • Li Y, Li AC, Shi H, Junga H, Jiang X, Naidong W, Lauterbach JH. (2006). Determination of S-phenylmercapturic acid in human urine using an automated sample extraction and fast liquid chromatographytandem mass spectrometric method. Biomed Chromatogr 20:597-604. (Pubitemid 44043404)
    • (2006) Biomedical Chromatography , vol.20 , Issue.6-7 , pp. 597-604
    • Li, Y.1    Li, A.C.2    Shi, H.3    Junga, H.4    Jiang, X.5    Naidong, W.6    Lauterbach, J.H.7
  • 35
    • 9144267855 scopus 로고    scopus 로고
    • An electrospray ionization tandem mass spectrometry based system with an online dual-loop cleanup device fro simultaneous quantitation of urinary benzene exposure biomarkers trans,trans-muconic acid and S-phenylmercapturic acid
    • Lin LC, Shih JF, Shih TS, Li YL, Liao PC. (2004). An electrospray ionization tandem mass spectrometry based system with an online dual-loop cleanup device fro simultaneous quantitation of urinary benzene exposure biomarkers trans,trans-muconic acid and S-phenylmercapturic acid. Rapid Comm Mass Spectrometry 18:2743-2752.
    • (2004) Rapid Comm Mass Spectrometry , vol.18 , pp. 2743-2752
    • Lin, L.C.1    Shih, J.F.2    Shih, T.S.3    Li, Y.L.4    Liao, P.C.5
  • 36
    • 45549110435 scopus 로고    scopus 로고
    • Relationships between levels of volatile organic compounds in air and blood from the general population
    • DOI 10.1038/sj.jes.7500635, PII 7500635
    • Lin YS, Egeghy PP, Rappaport SM. (2008). Relationships between levels of volatile organic compounds in air and blood from the general population. J Expo Sci Environ Epidemiol 18:421-429. (Pubitemid 351861559)
    • (2008) Journal of Exposure Science and Environmental Epidemiology , vol.18 , Issue.4 , pp. 421-429
    • Lin, Y.S.1    Egeghy, P.P.2    Rappaport, S.M.3
  • 38
    • 0037027018 scopus 로고    scopus 로고
    • Simultaneous determination of nicotine and eight nicotine metabolites in urine of smokers using liquid chromatographytandem mass spectrometry
    • Meger M, Meger-Kossien I, Schuler-Metz A, Janket D, Scherer G. (2002). Simultaneous determination of nicotine and eight nicotine metabolites in urine of smokers using liquid chromatographytandem mass spectrometry. J Chromatogr b Analyt Technol Biomed Life Sci 778:251-261.
    • (2002) J Chromatogr B Analyt Technol Biomed Life Sci , vol.778 , pp. 251-261
    • Meger, M.1    Meger-Kossien, I.2    Schuler-Metz, A.3    Janket, D.4    Scherer, G.5
  • 39
    • 77249165476 scopus 로고    scopus 로고
    • Occupational exposure to low levels of benzene: Biomarkers of exposure and nucleic acid oxidation and their modulation by polymorphic xenobiotic metabolizing enzymes
    • Manini P, De Palma G, Andreoli R, Mozzoni P, Poli D, Goldoni M, Petyx M, Apostoli P, Mutti A. (2010). Occupational exposure to low levels of benzene: Biomarkers of exposure and nucleic acid oxidation and their modulation by polymorphic xenobiotic metabolizing enzymes. Toxicol Lett 193:229-235.
    • (2010) Toxicol Lett , vol.193 , pp. 229-235
    • Manini, P.1    De Palma, G.2    Andreoli, R.3    Mozzoni, P.4    Poli, D.5    Goldoni, M.6    Petyx, M.7    Apostoli, P.8    Mutti, A.9
  • 40
    • 33751018237 scopus 로고    scopus 로고
    • Environmental and biological monitoring of benzene exposure in a cohort of Italian taxi drivers
    • DOI 10.1016/j.toxlet.2006.08.016, PII S0378427406012598
    • Manini P, De Palma G, Andreoli R, Poli D, Mozzoni P, Folesani G, Mutti A, Apostoli P. (2006). Environmental and biological monitoring of benzene exposure in a cohort of Italian taxi drivers. Toxicol Lett 167:142-151. (Pubitemid 44751379)
    • (2006) Toxicology Letters , vol.167 , Issue.2 , pp. 142-151
    • Manini, P.1    De Palma, G.2    Andreoli, R.3    Poli, D.4    Mozzoni, P.5    Folesani, G.6    Mutti, A.7    Apostoli, P.8
  • 42
    • 0032989171 scopus 로고    scopus 로고
    • Determination of the urinary benzene metabolites S-phenylmercapturic acid and trans,trans-muconic acid by liquid chromatography-tandem mass spectrometry
    • Melikian AA, O'Connor R, Prahalad AK, Hu P, Li H, Kagan M, Thompson S. (1999). Determination of the urinary benzene metabolites S-phenylmercapturic acid and trans,trans-muconic acid by liquid chromatography-tandem mass spectrometry. Carcinogenesis 20:719-726. (Pubitemid 29151313)
    • (1999) Carcinogenesis , vol.20 , Issue.4 , pp. 719-726
    • Melikian, A.A.1    O'Connor, R.2    Prahalad, A.K.3    Hu, P.4    Li, H.5    Kagan, M.6    Thompson, S.7
  • 43
    • 79957461111 scopus 로고    scopus 로고
    • NIOSH (National Institute Occupational Safety and Health),Last accessed 31-12-2010
    • NIOSH (National Institute Occupational Safety and Health)(2003). Hydrocarbons, Aromatic. Method 1501. Available online at: http:// www.cdc.gov/niosh/docs/2003-154/pdfs/1501.pdf. (Last accessed 31-12-2010).
    • (2003) Hydrocarbons, Aromatic. Method 1501
  • 44
    • 34347266973 scopus 로고    scopus 로고
    • Determination of free and total S-phenylmercapturic acid by HPLC/MS/MS in the biological monitoring of benzene exposure
    • DOI 10.1080/13547500601007943, PII 770192718
    • Paci E, Pigini D, Cialdella AM, Faranda P, Tranfo G. (2007). Determination of free and total S-phenylmercapturic acid by HPLC/MS/MS in the biological monitoring of benzene exposure. Biomarkers 12:111-122. (Pubitemid 47161393)
    • (2007) Biomarkers , vol.12 , Issue.2 , pp. 111-122
    • Paci, E.1    Pigini, D.2    Cialdella, A.M.3    Faranda, P.4    Tranfo, G.5
  • 46
    • 1842687249 scopus 로고    scopus 로고
    • Urinary benzene determination by SPME/GC-MS: A study of variables by fractional factorial design and response surface methodology
    • DOI 10.1016/j.jchromb.2004.01.020, PII S1570023204000595
    • Prado C, Garrido J, Periago JF. (2004). Urinary benzene determination by SPME/GC-MS. A study of variables by fractional factorial design and response surface methodology. J Chromatogr B Analyt Technol Biomed Life Sci 804:255-261. (Pubitemid 38481699)
    • (2004) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.804 , Issue.2 , pp. 255-261
    • Prado, C.1    Garrido, J.2    Periago, J.F.3
  • 47
    • 20444422947 scopus 로고    scopus 로고
    • Biomarkers of benzene: Urinary metabolites in relation to individual genotype and personal exposure
    • DOI 10.1016/j.cbi.2005.03.012, PII S0009279705000724, Proceedings of the International Symposium on Recent Advancis in Benzene Toxicity
    • Qu Q, Shore R, Li G, Su L, Jin X, Melikian AA, Roy N, Chen LC, Wirgin I, Cohen B, Yin S, Li Y, Mu R. (2005). Biomarkers of benzene; urinary metabolites in relation to individual genotype and personal exposure. Chemico-Biological Inter 153-154:85-95. (Pubitemid 40797798)
    • (2005) Chemico-Biological Interactions , vol.153-154 , pp. 85-95
    • Qu, Q.1    Shore, R.2    Li, G.3    Su, L.4    Jin, X.5    Melikian, A.A.6    Roy, N.7    Lung, C.C.8    Wirgin, I.9    Cohen, B.10    Yin, S.11    Li, Y.12    Mu, R.13
  • 48
    • 0026115074 scopus 로고
    • Assessment of long-term exposures to toxic substances in air
    • Rappaport SM. (1991). Assessment of long-term exposures to toxic substances in air. Ann Occup Hyg 35:61-121.
    • (1991) Ann Occup Hyg , vol.35 , pp. 61-121
    • Rappaport, S.M.1
  • 49
    • 0024004812 scopus 로고
    • A high pressure liquid chromatographic method for the separation and quantitation of water-soluble radiolabeled benzene metabolites
    • Sabourin PJ, Bechtold WE, Henderson RF. (1988). A high pressure liquid chromatographic method for the separation and quantitation of water-soluble radiolabeled benzene metabolites. Anal Biochem 170:316-327.
    • (1988) Anal Biochem , vol.170 , pp. 316-327
    • Sabourin, P.J.1    Bechtold, W.E.2    Henderson, R.F.3
  • 50
    • 39749163984 scopus 로고    scopus 로고
    • Fast determination of urinary S-phenylmercapturic acid (S-PMA) and S-benzylmercapturic acid (S-BMA) by column-switching liquid chromatography- tandem mass spectrometry
    • Schettgen T, Musiol A, Alt A, Kraus T. (2008). Fast determination of urinary S-phenylmercapturic acid (S-PMA) and S-benzylmercapturic acid (S-BMA) by column-switching liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 863:283-292.
    • (2008) J Chromatogr B Analyt Technol Biomed Life Sci , vol.863 , pp. 283-292
    • Schettgen, T.1    Musiol, A.2    Alt, A.3    Kraus, T.4
  • 51
    • 79957532413 scopus 로고    scopus 로고
    • Last accessed 31-12-2010
    • Sigma-Aldrich. (2010). Application Note Radiello, available online at: http://www.sigmaaldrich.com/etc/medialib/docs/Supelco/ Application-Notes/ radiello-d1-d6.Par.0001.File.tmp/radiello-d1-d6.pdf. (Last accessed 31-12-2010).
    • (2010) Application Note Radiello
  • 52
    • 8344258347 scopus 로고    scopus 로고
    • Benzene exposure assessed by metabolite excretion in Estonian oil shale mineworkers: Influence of glutathione s-transferase polymorphisms
    • Sørensen M, Poole J, Autrup H, Muzyka V, Jensen A, Loft S, Knudsen LE. (2004). Benzene exposure assessed by metabolite excretion in Estonian oil shale mineworkers: influence of glutathione s-transferase polymorphisms. Cancer Epidemiol Biomarkers Prev 13:1729-1735.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 1729-1735
    • Sørensen, M.1    Poole, J.2    Autrup, H.3    Muzyka, V.4    Jensen, A.5    Loft, S.6    Knudsen, L.E.7
  • 53
    • 77956885048 scopus 로고    scopus 로고
    • Enrichment and properties of urinary per-S-phenylmercapturic acid (pre-SPMA)
    • in press
    • Sterz K, Köhler D, Schettgen T, Scherer G. (2010). Enrichment and properties of urinary per-S-phenylmercapturic acid (pre-SPMA). J Chromatogr B (in press).
    • (2010) J Chromatogr B
    • Sterz, K.1    Köhler, D.2    Schettgen, T.3    Scherer, G.4
  • 54
    • 0024493038 scopus 로고
    • Determination of S-phenylmercapturic acid in the urine - An improvement in the biological monitoring of benzene exposure
    • Stommel P, Müller G, Stücker W, Verkoyen C, Schöbel S, Norpoth K. (1989). Determination of S-phenylmercapturic acid in the urine-an improvement in the biological monitoring of benzene exposure. Carcinogenesis 10:279-282. (Pubitemid 19050359)
    • (1989) Carcinogenesis , vol.10 , Issue.2 , pp. 279-282
    • Stommel, P.1    Muller, G.2    Stucker, W.3    Verkoyen, C.4    Schobel, S.5    Norpoth, K.6
  • 55
    • 77956811836 scopus 로고    scopus 로고
    • Comparison of hydrolysis and HPLC/MS/MS procedure with ELISA assay for the determination of S-phenylmercapturic acid as a biomarker of benzene exposure in human urine
    • Tranfo G, Bartolucci GB, Pigini D, Paci E, Scapellato ML, Doria D, Manno M, Carrieri M. (2010). Comparison of hydrolysis and HPLC/MS/MS procedure with ELISA assay for the determination of S-phenylmercapturic acid as a biomarker of benzene exposure in human urine. J Chromatogr B Analyt Technol Biomed Life Sci 878:2529-2533.
    • (2010) J Chromatogr B Analyt Technol Biomed Life Sci , vol.878 , pp. 2529-2533
    • Tranfo, G.1    Bartolucci, G.B.2    Pigini, D.3    Paci, E.4    Scapellato, M.L.5    Doria, D.6    Manno, M.7    Carrieri, M.8
  • 57
    • 1642503077 scopus 로고    scopus 로고
    • Rapid determination of six urinary benzene metabolites in occupationally exposed and unexposed subjects
    • DOI 10.1016/j.ab.2004.01.008, PII S0003269704000843
    • Waidyanatha S, Rothman N, Li G, Smith MT, Yin S, Rappaport SM. (2004). Rapid determination of six urinary benzene metabolites in occupationally exposed and unexposed subjects. Anal Biochem 327:184-199. (Pubitemid 38402187)
    • (2004) Analytical Biochemistry , vol.327 , Issue.2 , pp. 184-199
    • Waidyanatha, S.1    Rothman, N.2    Li, G.3    Smith, M.T.4    Yin, S.5    Rappaport, S.M.6


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