Determination of S-phenylmercapturic acid in human urine using an automated sample extraction and fast liquid chromatography-tandem mass spectrometric method

Biomedical Chromatography

Volumn 20, Issue 6-7, 2006, Pages 597-604

  Li, Yinghe ^a   Li, Austin C ^a   Shi, Haihong ^a   Junga, Heiko ^a   Jiang, Xiangyu ^a   Naidong, Weng ^a   Lauterbach, John H ^b  

^a 206 Carnegie Center   (United States)

^b R J Reynolds Tobacco Co   (United States)

Author keywords

High throughput bioanalysis; HPLC MS MS; Method development and validation; S phenylmercapturic acid

Indexed keywords

AUTOMATION; BODY FLUIDS; ELECTROSPRAY IONIZATION; EXTRACTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHASE SEPARATION;

FULLY AUTOMATED; HIGH-THROUGHPUT BIOANALYSIS; HPLC-MS-MS; HUMAN URINE; LC-MS-MS; METHOD DEVELOPMENT; METHOD VALIDATIONS; MS/MS ANALYSIS; S-PHENYLMERCAPTURIC ACID; URINE SAMPLE;

QUALITY CONTROL;

ACETYLCYSTEINE DERIVATIVE; BENZENE; BIOLOGICAL MARKER; PHENYLMERCAPTURIC ACID; UNCLASSIFIED DRUG;

ACCURACY; ANALYTICAL ERROR; ANION EXCHANGE; ARTICLE; AUTOMATION; CALIBRATION; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG URINE LEVEL; ELECTROSPRAY; ENVIRONMENTAL EXPOSURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; HUMAN; ISOTOPE LABELING; QUALITY CONTROL; SENSITIVITY AND SPECIFICITY; SMOKING HABIT; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; URINALYSIS; VALIDATION PROCESS;

EID: 33745918301     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.653     Document Type: Article

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