Chemoprevention molecular and biochemical mechanisms involved in cancer control and management

Health Science Journal

Volumn 5, Issue 2, 2011, Pages 149-156

  Karikas, George Albert ^a  

^a UNIVERSITY OF WEST ATTICA   (Greece)

Author keywords

Cancer chemoprevention; Drugs; Epigenetic mechanisms; Phytochemicals; Polyphenols

Indexed keywords

EID: 79957476232     PISSN: 11087366     EISSN: 1791809X     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Trosko JE. The role of stem cells and gap junctions as targets for cancer chemoprevention and chemotherapy. Biomed Pharmacother 2005; 59:326-331.
2. Karikas GA. Anticancer and chemopreventing natural products: some biochemical and therapeutic aspects. Journal of B.U. ON 2010; 15 (4): 627-638
3. Coseri S. Natural products and their analogues as efficient anticancer drugs. Mini Rev Med Chem 2009; 9: 560-571.
4. Brenner DE., Gescher AJ. Cancer chemoprevention:lessons learned and future directions. Br J Cancer 2005; 93:735-739.
5. Chaturvedi P, Bhui K, Shukla Y. Lupeol: Connotations for chemoprevention. Cancer Letters 2008; 263: 1-13.
6. Neergheen VS, Bahorun T, Taylor EW, Jen LS, Aruoma OI. Targeting specific cell signaling transduction pathways by dietary and medicinal phytochemicals in cancer chemoprevention. Toxicology 2009 Oct 20 (Epub ahead of print)
7. Ellis L., Atadja PW., Johnstone RW. Epigenetics in cancer: targeting chromatin modifications. Mol Cancer Ther 2009; 8 (6): 1409-1420.
8. Linka A., Balaguera FA. Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics. Biochemical Pharmacology 2010;12(15):1791-1792.
9. Karikas G.A., Constantinou-Kokotou V., Kokotos G. An HPLC method for the measurement of polyamines and lipidic amines binding to DNA. Journal of Liquid Chromatography and Related Technologies, 1997; 20 (11): 1789-1796.
10. Dolinoy DC., Huang D., Jirtle RT. Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development, Proc Natl Acad Sci USA 2007;104(32): 13056-13061.
11. Williams MT., Hord NG. The role of dietary factors in cancer prevention: beyond fruits and vegetables. Nutr Clin Pract 2005;20:451-459.
12. Nishino H., Satomi Y., Tokuda H., Masuda M. Cancer control by phytochemicals. Curr Pharm Des 2007;13:3394-3399.
13. Nagaraj S., Sunitha S., Varalakshmi P. Effect of lupeol on the lipid peroxidation and antioxidant status in rat kidney after chronic cadmium exposure. J Appl Toxicol 2000; 20:413-417.
14. Saleem M., Afaq F., Adhami VM., Mukhtar H. Lupeol modulates NF-KappaB and P13K/Akt pathway and inhibits skin cancer in CD-1 mice. Oncogene 2004; 23:5203-5214.
15. Karikas GA., Euerby MR., Waigh RD. Constituents of the Stems of Arbutus unedo. Planta Medica 1987; 2: 223-224.
16. Saleem M. Lupeol, novel anti-inflammatory and anticancer dietary triterpene. Cancer Letters 2009; 285:109-115.
17. Prasad S., Ravindran J., Aggarwal BB. NF-kappaB and cancer: how intimate is this relationship. Mol Cell Biochem 2010; 336:25-37.
18. Strimpakos A., Sharma RA. Antioxidants and Redox. Signaling 2008; 10: 511-546.
19. Bartik LG., Whitfield K., Kaczmarska M., Lowmiller CL., Moffet EW., Furmick JK. et al. Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention. J Nutr Biochem 2010;21(12):1153-1161
20. Bachmeier BE., Killian P., Pfeffer U., Nerlich AG. Novel aspects for the application of Curcumin in chemoprevention of various cancers. Front Biosci (Schol Ed) 2010;2:697-717.
21. Park K., Chun KS., Lee J M., Lee SS., Surh YJ. Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithin decarboxylase activity and skin tumor promotion in ICR mice. Cancer Lett 1998; 129: 139-144.
22. Surh YJ., Lee SS. Capsaicin, a double-edged sword: toxicity, metabolism, and chemopreventive potential. Life Sci 1995; 56: 1845-1855.
23. Nomura M., Ma W., Chen N., Bode AM., Dong Z. Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced NF-κB activation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins. Carcinogenesis 2000; 21: 1885-1890.
24. Tacchini L., Dansi P., Matteucci E., Desiderio MA. Hepatocyte growth factor signal coupling to various transcription factors depends on triggering of Met receptor and protein kinase transducers in human hepatoma cells HepG2. Exp Cell Res 2000; 256: 272-281.
25. Subbaramaiah K. Resveratrol inhibits cyclooxygenase-2 transcription in human mammary epithelial cells. Ann NY Acad Sci 1999; 889: 214-223.
26. Mouria M. Food-derived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome C release and apoptosis. Int J Cancer 2002; 98: 761-769.
27. Hadi SM., Ullah MF., Azmi AS. Resveratrol Mobilizes Endogenous Copper in Human Peripheral Lymphocytes Leading to Oxidative DNA Breakage: A Putative Mechanism for Chemoprevention of Cancer. Pharm Res 2010 Jan 30 (in press).
28. Bharti, AC., Aggarwal, BB. Nuclear factor-kB and cancer: its role in prevention and therapy. Biochem Pharmacol 2002; 64: 883-888.
29. Mahmoud NN. Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis. Carcinogenesis 2000; 21: 921-927.
30. Jaiswal AS., Marlow BP., Gupta N., Narayan S. β-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells. Oncogene 2002; 21: 8414-8427.
31. Joe AK. Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines. Clin Cancer Res 2002; 8: 893-903.
32. Orner GA. Response of Apcmin and A33ΔNβ-cat mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Mutat Res 2002; 506-507: 121-127.
33. Blum CA. β-Catenin mutation in rat colon tumors initiated by 1,2-dimethylhydrazine and 2-amino-3-methylimidazo[4,5-f]quinoline, and the effect of post initiation treatment with chlorophyllin and indole-3-carbinol. Carcinogenesis 2001; 22: 315-320.
34. Meng Q. Suppression of breast cancer invasion and migration by indole-3-carbinol: associated with upregulation of BRCA1 and E-cadherin/catenin complexes. J Mol Med 2000; 78: 155-165.
35. Brack ME. The citrus methoxyflavone tangeretin affects human cell-cell interactions. Adv Exp Med Biol 2002; 505: 135-139.
36. Mori H. Chemoprevention of large bowel carcinogenesis; the role of control of cell proliferation and significance of β-catenin-accumulated crypts as a new biomarker. Eur. J. Cancer Prev 2002; 11 (Suppl 2): S71-S75.
37. Miyamoto K., Ushijima T. Diagnostic and therapeutic applications of epigenetics, Jpn J Clin Oncol 2005;35(6): 293-301.
38. Gilbert J., Gore SD., Herman JG., Carducci MA. The clinical application of targeting cancer through histone acetylation and hypomethylation, Clin Cancer Res 2004;(14): 4589-4596.
39. Horrobin DF. Are large clinical trials in rapidly lethal diseases usually unethical?, Lancet 2003;361(9358): 695-697.
40. Lee BH., S. Yegnasubramanian S., Lin X., Nelson WG. Procainamide is a specific inhibitor of DNA methyltransferase 1. J Biol Chem 2005; 280 (49): 40749-40756.
41. Tada M., Imazeki F., Fukai K., Sakamoto A., Arai M., Mikata R. et al. Procaine inhibits the proliferation and DNA methylation in human hepatoma cells. Hepatol Int 1 2007; 3: 355-364.
42. Gao Z., Xu Z., Hung MS., Lin YC., Wang T., Gong M. et al. Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells. Anticancer Res 2009; 29 (6): 2025-2030.
43. Gu B., Ding Q., Xia G, Fang Z. EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression. Oncol Rep 2009; 21 (3):635-640.
44. Jones K, Nourse J., G. Corbett G., Gandhi MK. Sodium valproate in combination with ganciclovir induces lysis of EBV-infected lymphoma cells without impairing EBV-specific T-cell immunity. Int J Lab Hematol 2010; 32: e169-e174.
45. Hurtubise A., Bernstein ML., Momparle RL. Preclinical evaluation of the antineoplastic action of 5-aza-2′-deoxycytidine and different histone deacetylase inhibitors on human Ewing's sarcoma cells. Cancer Cell Int 2008; 8: 16.
46. Duvic M, Talpur R, Ni X., Zhang C., Hazarika P., Kelly C. et al. Phase II trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL). Blood 2007;109:31-9.
47. Sato N., Maitra A., Fukushima N., van Heek NT., Matsubayashi H., Iacobuzio-Donahue CA. et al. Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma. Cancer Res 2003; 63 (14): 4158-4166.
48. Issa J-P. DNA Methylation as a therapeutic target in cancer. Clin Cancer Res 2007;13:1634-7.