메뉴 건너뛰기




Volumn 11, Issue , 2011, Pages

P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferation

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN P53; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

EID: 79957471582     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-11-203     Document Type: Article
Times cited : (86)

References (58)
  • 1
    • 0038793948 scopus 로고    scopus 로고
    • Apoptosis and melanoma chemoresistance
    • 10.1038/sj.onc.1206454, 12789290
    • Soengas MS, Lowe SW. Apoptosis and melanoma chemoresistance. Oncogene 2003, 22:3138-3151. 10.1038/sj.onc.1206454, 12789290.
    • (2003) Oncogene , vol.22 , pp. 3138-3151
    • Soengas, M.S.1    Lowe, S.W.2
  • 3
    • 4344656396 scopus 로고    scopus 로고
    • Management of cutaneous melanoma
    • 10.1056/NEJMra041245, 15342808
    • Tsao H, Atkins MB, Sober AJ. Management of cutaneous melanoma. N Engl J Med 2004, 351:998-1012. 10.1056/NEJMra041245, 15342808.
    • (2004) N Engl J Med , vol.351 , pp. 998-1012
    • Tsao, H.1    Atkins, M.B.2    Sober, A.J.3
  • 4
    • 0035751937 scopus 로고    scopus 로고
    • Assessing TP53 status in human tumours to evaluate clinical outcome
    • 10.1038/35106009, 11902578
    • Soussi T, Beroud C. Assessing TP53 status in human tumours to evaluate clinical outcome. Nat Rev Cancer 2001, 1:233-240. 10.1038/35106009, 11902578.
    • (2001) Nat Rev Cancer , vol.1 , pp. 233-240
    • Soussi, T.1    Beroud, C.2
  • 6
    • 30444461024 scopus 로고    scopus 로고
    • Comprehensive analysis of the p53 status in mucosal and cutaneous melanomas
    • 10.1002/ijc.21366, 16094622
    • Gwosdz C, Scheckenbach K, Lieven O, Reifenberger J, Knopf A, Bier H, Balz V. Comprehensive analysis of the p53 status in mucosal and cutaneous melanomas. Int J Cancer 2006, 118:577-582. 10.1002/ijc.21366, 16094622.
    • (2006) Int J Cancer , vol.118 , pp. 577-582
    • Gwosdz, C.1    Scheckenbach, K.2    Lieven, O.3    Reifenberger, J.4    Knopf, A.5    Bier, H.6    Balz, V.7
  • 7
    • 26444451975 scopus 로고    scopus 로고
    • Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B
    • 10.1186/1471-2407-5-36, 1097717, 15819981
    • Soto JL, Cabrera CM, Serrano S, Lopez-Nevot MA. Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B. BMC Cancer 2005, 5:36. 10.1186/1471-2407-5-36, 1097717, 15819981.
    • (2005) BMC Cancer , vol.5 , pp. 36
    • Soto, J.L.1    Cabrera, C.M.2    Serrano, S.3    Lopez-Nevot, M.A.4
  • 8
    • 0032998108 scopus 로고    scopus 로고
    • P53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis
    • 10.1038/sj.bjc.6690147, 2362648, 10070891
    • Zerp SF, van Elsas A, Peltenburg LT, Schrier PI. p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis. Br J Cancer 1999, 79:921-926. 10.1038/sj.bjc.6690147, 2362648, 10070891.
    • (1999) Br J Cancer , vol.79 , pp. 921-926
    • Zerp, S.F.1    van Elsas, A.2    Peltenburg, L.T.3    Schrier, P.I.4
  • 9
    • 0028938104 scopus 로고
    • P53 gene mutation and expression in naevi and melanomas
    • 10.1097/00008390-199504000-00004, 7620345
    • Sparrow LE, Soong R, Dawkins HJ, Iacopetta BJ, Heenan PJ. p53 gene mutation and expression in naevi and melanomas. Melanoma Res 1995, 5:93-100. 10.1097/00008390-199504000-00004, 7620345.
    • (1995) Melanoma Res , vol.5 , pp. 93-100
    • Sparrow, L.E.1    Soong, R.2    Dawkins, H.J.3    Iacopetta, B.J.4    Heenan, P.J.5
  • 10
    • 33845496093 scopus 로고    scopus 로고
    • P53 downstream target genes and tumor suppression: a classical view in evolution
    • 10.1038/sj.cdd.4402058, 17068503
    • Rozan LM, El-Deiry WS. p53 downstream target genes and tumor suppression: a classical view in evolution. Cell Death Differ 2007, 14:3-9. 10.1038/sj.cdd.4402058, 17068503.
    • (2007) Cell Death Differ , vol.14 , pp. 3-9
    • Rozan, L.M.1    El-Deiry, W.S.2
  • 11
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: the cell's response to p53
    • 10.1038/nrc864, 12154352
    • Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2002, 2:594-604. 10.1038/nrc864, 12154352.
    • (2002) Nat Rev Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 12
    • 33646807491 scopus 로고    scopus 로고
    • Transcriptional regulation by p53: one protein, many possibilities
    • 10.1038/sj.cdd.4401916, 16575405
    • Laptenko O, Prives C. Transcriptional regulation by p53: one protein, many possibilities. Cell Death Differ 2006, 13:951-961. 10.1038/sj.cdd.4401916, 16575405.
    • (2006) Cell Death Differ , vol.13 , pp. 951-961
    • Laptenko, O.1    Prives, C.2
  • 13
    • 18144416611 scopus 로고    scopus 로고
    • The transcriptional targets of p53 in apoptosis control
    • 10.1016/j.bbrc.2005.03.189, 15865941
    • Yu J, Zhang L. The transcriptional targets of p53 in apoptosis control. Biochem Biophys Res Commun 2005, 331:851-858. 10.1016/j.bbrc.2005.03.189, 15865941.
    • (2005) Biochem Biophys Res Commun , vol.331 , pp. 851-858
    • Yu, J.1    Zhang, L.2
  • 16
    • 41549150851 scopus 로고    scopus 로고
    • Small molecular weight variants of p53 are expressed in human melanoma cells and are induced by the DNA damaging agent cisplatin
    • 10.1158/1078-0432.CCR-07-1422, 18310316
    • Avery-Kiejda KA, Zhang XD, Adams LJ, Scott RJ, Vojtesek B, Lane DP, Hersey P. Small molecular weight variants of p53 are expressed in human melanoma cells and are induced by the DNA damaging agent cisplatin. Clin Cancer Res 2008, 14:1659-1668. 10.1158/1078-0432.CCR-07-1422, 18310316.
    • (2008) Clin Cancer Res , vol.14 , pp. 1659-1668
    • Avery-Kiejda, K.A.1    Zhang, X.D.2    Adams, L.J.3    Scott, R.J.4    Vojtesek, B.5    Lane, D.P.6    Hersey, P.7
  • 17
    • 0042066359 scopus 로고    scopus 로고
    • Melanoma cells can tolerate high levels of transcriptionally active endogenous p53 but are sensitive to retrovirus-transduced p53
    • 10.1038/sj.onc.1206741, 12894234
    • Kichina JV, Rauth S, Das Gupta TK, Gudkov AV. Melanoma cells can tolerate high levels of transcriptionally active endogenous p53 but are sensitive to retrovirus-transduced p53. Oncogene 2003, 22:4911-4917. 10.1038/sj.onc.1206741, 12894234.
    • (2003) Oncogene , vol.22 , pp. 4911-4917
    • Kichina, J.V.1    Rauth, S.2    Das Gupta, T.K.3    Gudkov, A.V.4
  • 20
    • 34147097875 scopus 로고    scopus 로고
    • The increased expression of Y box-binding protein 1 in melanoma stimulates proliferation and tumor invasion, antagonizes apoptosis and enhances chemoresistance
    • 10.1002/ijc.22512, 17266041
    • Schittek B, Psenner K, Sauer B, Meier F, Iftner T, Garbe C. The increased expression of Y box-binding protein 1 in melanoma stimulates proliferation and tumor invasion, antagonizes apoptosis and enhances chemoresistance. Int J Cancer 2007, 120:2110-2118. 10.1002/ijc.22512, 17266041.
    • (2007) Int J Cancer , vol.120 , pp. 2110-2118
    • Schittek, B.1    Psenner, K.2    Sauer, B.3    Meier, F.4    Iftner, T.5    Garbe, C.6
  • 21
    • 0013583837 scopus 로고    scopus 로고
    • Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
    • Zhang XD, Franco A, Myers K, Gray C, Nguyen T, Hersey P. Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res 1999, 59:2747-2753.
    • (1999) Cancer Res , vol.59 , pp. 2747-2753
    • Zhang, X.D.1    Franco, A.2    Myers, K.3    Gray, C.4    Nguyen, T.5    Hersey, P.6
  • 22
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • 10.1126/science.1068999, 11910072
    • Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002, 296:550-553. 10.1126/science.1068999, 11910072.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 23
    • 0031710033 scopus 로고    scopus 로고
    • A third-generation lentivirus vector with a conditional packaging system
    • 110254, 9765382
    • Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, Trono D, Naldini L. A third-generation lentivirus vector with a conditional packaging system. J Virol 1998, 72:8463-8471. 110254, 9765382.
    • (1998) J Virol , vol.72 , pp. 8463-8471
    • Dull, T.1    Zufferey, R.2    Kelly, M.3    Mandel, R.J.4    Nguyen, M.5    Trono, D.6    Naldini, L.7
  • 24
    • 0034083194 scopus 로고    scopus 로고
    • Production and concentration of pseudotyped HIV-1-based gene transfer vectors
    • 10.1038/sj.gt.3301188, 10849549
    • Reiser J. Production and concentration of pseudotyped HIV-1-based gene transfer vectors. Gene Ther 2000, 7:910-913. 10.1038/sj.gt.3301188, 10849549.
    • (2000) Gene Ther , vol.7 , pp. 910-913
    • Reiser, J.1
  • 25
    • 79959499775 scopus 로고    scopus 로고
    • SOURCE
    • SOURCE. , http://smd.stanford.edu/cgi-bin/source/sourceSearch
  • 26
    • 84871629524 scopus 로고    scopus 로고
    • PANTHER Classification system
    • PANTHER Classification system. , http://www.pantherdb.org
  • 27
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • 10.1006/meth.2001.1262, 11846609
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408. 10.1006/meth.2001.1262, 11846609.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 28
    • 35648934994 scopus 로고    scopus 로고
    • Temozolomide induces senescence but not apoptosis in human melanoma cells
    • 10.1038/sj.bjc.6604017, 2360470, 17968428
    • Mhaidat NM, Zhang XD, Allen J, Avery-Kiejda KA, Scott RJ, Hersey P. Temozolomide induces senescence but not apoptosis in human melanoma cells. Br J Cancer 2007, 97:1225-1233. 10.1038/sj.bjc.6604017, 2360470, 17968428.
    • (2007) Br J Cancer , vol.97 , pp. 1225-1233
    • Mhaidat, N.M.1    Zhang, X.D.2    Allen, J.3    Avery-Kiejda, K.A.4    Scott, R.J.5    Hersey, P.6
  • 30
    • 0028089956 scopus 로고
    • Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines
    • 10.1002/ijc.2910590209, 7927918
    • Zabrenetzky V, Harris CC, Steeg PS, Roberts DD. Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines. Int J Cancer 1994, 59:191-195. 10.1002/ijc.2910590209, 7927918.
    • (1994) Int J Cancer , vol.59 , pp. 191-195
    • Zabrenetzky, V.1    Harris, C.C.2    Steeg, P.S.3    Roberts, D.D.4
  • 31
    • 36048965904 scopus 로고    scopus 로고
    • Down-regulation of surface fractalkine by RNA interference in B16 melanoma reduced tumor growth in mice
    • 10.1016/j.bbrc.2007.10.124, 17971299
    • Ren T, Chen Q, Tian Z, Wei H. Down-regulation of surface fractalkine by RNA interference in B16 melanoma reduced tumor growth in mice. Biochem Biophys Res Commun 2007, 364:978-984. 10.1016/j.bbrc.2007.10.124, 17971299.
    • (2007) Biochem Biophys Res Commun , vol.364 , pp. 978-984
    • Ren, T.1    Chen, Q.2    Tian, Z.3    Wei, H.4
  • 33
    • 0036606349 scopus 로고    scopus 로고
    • An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli
    • 10.1093/nar/30.11.2398, 117192, 12034827
    • Hashimoto Y, Zhang C, Kawauchi J, Imoto I, Adachi MT, Inazawa J, Amagasa T, Hai T, Kitajima S. An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli. Nucleic Acids Res 2002, 30:2398-2406. 10.1093/nar/30.11.2398, 117192, 12034827.
    • (2002) Nucleic Acids Res , vol.30 , pp. 2398-2406
    • Hashimoto, Y.1    Zhang, C.2    Kawauchi, J.3    Imoto, I.4    Adachi, M.T.5    Inazawa, J.6    Amagasa, T.7    Hai, T.8    Kitajima, S.9
  • 35
    • 0038182453 scopus 로고    scopus 로고
    • A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein
    • 10.1093/emboj/cdg274, 156770, 12773400
    • Foray N, Marot D, Gabriel A, Randrianarison V, Carr AM, Perricaudet M, Ashworth A, Jeggo P. A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein. Embo J 2003, 22:2860-2871. 10.1093/emboj/cdg274, 156770, 12773400.
    • (2003) Embo J , vol.22 , pp. 2860-2871
    • Foray, N.1    Marot, D.2    Gabriel, A.3    Randrianarison, V.4    Carr, A.M.5    Perricaudet, M.6    Ashworth, A.7    Jeggo, P.8
  • 36
    • 3843066731 scopus 로고    scopus 로고
    • BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage
    • 10.1074/jbc.M405372200, 15159397
    • Fabbro M, Savage K, Hobson K, Deans AJ, Powell SN, McArthur GA, Khanna KK. BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage. J Biol Chem 2004, 279:31251-31258. 10.1074/jbc.M405372200, 15159397.
    • (2004) J Biol Chem , vol.279 , pp. 31251-31258
    • Fabbro, M.1    Savage, K.2    Hobson, K.3    Deans, A.J.4    Powell, S.N.5    McArthur, G.A.6    Khanna, K.K.7
  • 37
    • 34248185454 scopus 로고    scopus 로고
    • P53: guardian of the genome and policeman of the oncogenes
    • 10.4161/cc.6.9.4211, 17457049
    • Efeyan A, Serrano M. p53: guardian of the genome and policeman of the oncogenes. Cell Cycle 2007, 6:1006-1010. 10.4161/cc.6.9.4211, 17457049.
    • (2007) Cell Cycle , vol.6 , pp. 1006-1010
    • Efeyan, A.1    Serrano, M.2
  • 38
    • 18344377030 scopus 로고    scopus 로고
    • The p53 pathway: positive and negative feedback loops
    • 10.1038/sj.onc.1208615, 15838523
    • Harris SL, Levine AJ. The p53 pathway: positive and negative feedback loops. Oncogene 2005, 24:2899-2908. 10.1038/sj.onc.1208615, 15838523.
    • (2005) Oncogene , vol.24 , pp. 2899-2908
    • Harris, S.L.1    Levine, A.J.2
  • 39
    • 0038819652 scopus 로고    scopus 로고
    • The INK4a/ARF locus and melanoma
    • 10.1038/sj.onc.1206461, 12789286
    • Sharpless E, Chin L. The INK4a/ARF locus and melanoma. Oncogene 2003, 22:3092-3098. 10.1038/sj.onc.1206461, 12789286.
    • (2003) Oncogene , vol.22 , pp. 3092-3098
    • Sharpless, E.1    Chin, L.2
  • 40
    • 35948959024 scopus 로고    scopus 로고
    • The universal character of the tumor-associated antigen survivin
    • 10.1158/1078-0432.CCR-07-0686, 17947459
    • Andersen MH, Svane IM, Becker JC, Straten PT. The universal character of the tumor-associated antigen survivin. Clin Cancer Res 2007, 13:5991-5994. 10.1158/1078-0432.CCR-07-0686, 17947459.
    • (2007) Clin Cancer Res , vol.13 , pp. 5991-5994
    • Andersen, M.H.1    Svane, I.M.2    Becker, J.C.3    Straten, P.T.4
  • 41
    • 38849209818 scopus 로고    scopus 로고
    • Survivin repression by p53, Rb and E2F2 in normal human melanocytes
    • 2292458, 17916908
    • Raj D, Liu T, Samadashwily G, Li F, Grossman D. Survivin repression by p53, Rb and E2F2 in normal human melanocytes. Carcinogenesis 2008, 29:194-201. 2292458, 17916908.
    • (2008) Carcinogenesis , vol.29 , pp. 194-201
    • Raj, D.1    Liu, T.2    Samadashwily, G.3    Li, F.4    Grossman, D.5
  • 43
    • 33846148980 scopus 로고    scopus 로고
    • Outcomes of p53 activation--spoilt for choice
    • 10.1242/jcs.03293, 17158908
    • Vousden KH. Outcomes of p53 activation--spoilt for choice. J Cell Sci 2006, 119:5015-5020. 10.1242/jcs.03293, 17158908.
    • (2006) J Cell Sci , vol.119 , pp. 5015-5020
    • Vousden, K.H.1
  • 44
    • 44049092395 scopus 로고    scopus 로고
    • The dark side of a tumor suppressor: anti-apoptotic p53
    • 10.1038/cdd.2008.33, 18356920
    • Janicke RU, Sohn D, Schulze-Osthoff K. The dark side of a tumor suppressor: anti-apoptotic p53. Cell Death Differ 2008, 15:959-976. 10.1038/cdd.2008.33, 18356920.
    • (2008) Cell Death Differ , vol.15 , pp. 959-976
    • Janicke, R.U.1    Sohn, D.2    Schulze-Osthoff, K.3
  • 45
    • 0030026934 scopus 로고    scopus 로고
    • Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis
    • 10.1038/nm0196-72, 8564846
    • Wahl AF, Donaldson KL, Fairchild C, Lee FY, Foster SA, Demers GW, Galloway DA. Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis. Nat Med 1996, 2:72-79. 10.1038/nm0196-72, 8564846.
    • (1996) Nat Med , vol.2 , pp. 72-79
    • Wahl, A.F.1    Donaldson, K.L.2    Fairchild, C.3    Lee, F.Y.4    Foster, S.A.5    Demers, G.W.6    Galloway, D.A.7
  • 47
    • 0030021996 scopus 로고    scopus 로고
    • Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents
    • Hawkins DS, Demers GW, Galloway DA. Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents. Cancer Res 1996, 56:892-898.
    • (1996) Cancer Res , vol.56 , pp. 892-898
    • Hawkins, D.S.1    Demers, G.W.2    Galloway, D.A.3
  • 49
    • 30444457740 scopus 로고    scopus 로고
    • Knock down of p53 levels in human keratinocytes increases susceptibility to type I and type II interferon-induced apoptosis mediated by a TRAIL dependent pathway
    • 10.1016/j.jdermsci.2005.10.003, 16289694
    • Chaturvedi V, Bodner B, Qin JZ, Nickoloff BJ. Knock down of p53 levels in human keratinocytes increases susceptibility to type I and type II interferon-induced apoptosis mediated by a TRAIL dependent pathway. J Dermatol Sci 2006, 41:31-41. 10.1016/j.jdermsci.2005.10.003, 16289694.
    • (2006) J Dermatol Sci , vol.41 , pp. 31-41
    • Chaturvedi, V.1    Bodner, B.2    Qin, J.Z.3    Nickoloff, B.J.4
  • 50
    • 24044494290 scopus 로고    scopus 로고
    • Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis
    • 10.1038/sj.onc.1208650, 15940268
    • Chaturvedi V, Sitailo LA, Qin JZ, Bodner B, Denning MF, Curry J, Zhang W, Brash D, Nickoloff BJ. Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis. Oncogene 2005, 24:5299-5312. 10.1038/sj.onc.1208650, 15940268.
    • (2005) Oncogene , vol.24 , pp. 5299-5312
    • Chaturvedi, V.1    Sitailo, L.A.2    Qin, J.Z.3    Bodner, B.4    Denning, M.F.5    Curry, J.6    Zhang, W.7    Brash, D.8    Nickoloff, B.J.9
  • 52
    • 27744547091 scopus 로고    scopus 로고
    • Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma
    • 10.1016/j.cell.2005.09.029, 16286009
    • Wu WS, Heinrichs S, Xu D, Garrison SP, Zambetti GP, Adams JM, Look AT. Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma. Cell 2005, 123:641-653. 10.1016/j.cell.2005.09.029, 16286009.
    • (2005) Cell , vol.123 , pp. 641-653
    • Wu, W.S.1    Heinrichs, S.2    Xu, D.3    Garrison, S.P.4    Zambetti, G.P.5    Adams, J.M.6    Look, A.T.7
  • 53
    • 16844387097 scopus 로고    scopus 로고
    • Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas
    • 10.1158/0008-5472.CAN-04-3045, 15781639
    • Vance KW, Carreira S, Brosch G, Goding CR. Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas. Cancer Res 2005, 65:2260-2268. 10.1158/0008-5472.CAN-04-3045, 15781639.
    • (2005) Cancer Res , vol.65 , pp. 2260-2268
    • Vance, K.W.1    Carreira, S.2    Brosch, G.3    Goding, C.R.4
  • 55
    • 4944255743 scopus 로고    scopus 로고
    • Post-translational modification of p53 in tumorigenesis
    • 10.1038/nrc1455, 15510160
    • Bode AM, Dong Z. Post-translational modification of p53 in tumorigenesis. Nat Rev Cancer 2004, 4:793-805. 10.1038/nrc1455, 15510160.
    • (2004) Nat Rev Cancer , vol.4 , pp. 793-805
    • Bode, A.M.1    Dong, Z.2
  • 58
    • 35748961986 scopus 로고    scopus 로고
    • P53 enters the microRNA world
    • 10.1016/j.ccr.2007.10.028, 17996645
    • Hermeking H. p53 enters the microRNA world. Cancer Cell 2007, 12:414-418. 10.1016/j.ccr.2007.10.028, 17996645.
    • (2007) Cancer Cell , vol.12 , pp. 414-418
    • Hermeking, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.