-
1
-
-
0038793948
-
Apoptosis and melanoma chemoresistance
-
10.1038/sj.onc.1206454, 12789290
-
Soengas MS, Lowe SW. Apoptosis and melanoma chemoresistance. Oncogene 2003, 22:3138-3151. 10.1038/sj.onc.1206454, 12789290.
-
(2003)
Oncogene
, vol.22
, pp. 3138-3151
-
-
Soengas, M.S.1
Lowe, S.W.2
-
3
-
-
4344656396
-
Management of cutaneous melanoma
-
10.1056/NEJMra041245, 15342808
-
Tsao H, Atkins MB, Sober AJ. Management of cutaneous melanoma. N Engl J Med 2004, 351:998-1012. 10.1056/NEJMra041245, 15342808.
-
(2004)
N Engl J Med
, vol.351
, pp. 998-1012
-
-
Tsao, H.1
Atkins, M.B.2
Sober, A.J.3
-
4
-
-
0035751937
-
Assessing TP53 status in human tumours to evaluate clinical outcome
-
10.1038/35106009, 11902578
-
Soussi T, Beroud C. Assessing TP53 status in human tumours to evaluate clinical outcome. Nat Rev Cancer 2001, 1:233-240. 10.1038/35106009, 11902578.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 233-240
-
-
Soussi, T.1
Beroud, C.2
-
5
-
-
33747599365
-
The role of cell cycle regulatory proteins in the pathogenesis of melanoma
-
10.1080/00313020600817951, 16916716
-
Li W, Sanki A, Karim RZ, Thompson JF, Soon Lee C, Zhuang L, McCarthy SW, Scolyer RA. The role of cell cycle regulatory proteins in the pathogenesis of melanoma. Pathology 2006, 38:287-301. 10.1080/00313020600817951, 16916716.
-
(2006)
Pathology
, vol.38
, pp. 287-301
-
-
Li, W.1
Sanki, A.2
Karim, R.Z.3
Thompson, J.F.4
Soon Lee, C.5
Zhuang, L.6
McCarthy, S.W.7
Scolyer, R.A.8
-
6
-
-
30444461024
-
Comprehensive analysis of the p53 status in mucosal and cutaneous melanomas
-
10.1002/ijc.21366, 16094622
-
Gwosdz C, Scheckenbach K, Lieven O, Reifenberger J, Knopf A, Bier H, Balz V. Comprehensive analysis of the p53 status in mucosal and cutaneous melanomas. Int J Cancer 2006, 118:577-582. 10.1002/ijc.21366, 16094622.
-
(2006)
Int J Cancer
, vol.118
, pp. 577-582
-
-
Gwosdz, C.1
Scheckenbach, K.2
Lieven, O.3
Reifenberger, J.4
Knopf, A.5
Bier, H.6
Balz, V.7
-
7
-
-
26444451975
-
Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B
-
10.1186/1471-2407-5-36, 1097717, 15819981
-
Soto JL, Cabrera CM, Serrano S, Lopez-Nevot MA. Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B. BMC Cancer 2005, 5:36. 10.1186/1471-2407-5-36, 1097717, 15819981.
-
(2005)
BMC Cancer
, vol.5
, pp. 36
-
-
Soto, J.L.1
Cabrera, C.M.2
Serrano, S.3
Lopez-Nevot, M.A.4
-
8
-
-
0032998108
-
P53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis
-
10.1038/sj.bjc.6690147, 2362648, 10070891
-
Zerp SF, van Elsas A, Peltenburg LT, Schrier PI. p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis. Br J Cancer 1999, 79:921-926. 10.1038/sj.bjc.6690147, 2362648, 10070891.
-
(1999)
Br J Cancer
, vol.79
, pp. 921-926
-
-
Zerp, S.F.1
van Elsas, A.2
Peltenburg, L.T.3
Schrier, P.I.4
-
9
-
-
0028938104
-
P53 gene mutation and expression in naevi and melanomas
-
10.1097/00008390-199504000-00004, 7620345
-
Sparrow LE, Soong R, Dawkins HJ, Iacopetta BJ, Heenan PJ. p53 gene mutation and expression in naevi and melanomas. Melanoma Res 1995, 5:93-100. 10.1097/00008390-199504000-00004, 7620345.
-
(1995)
Melanoma Res
, vol.5
, pp. 93-100
-
-
Sparrow, L.E.1
Soong, R.2
Dawkins, H.J.3
Iacopetta, B.J.4
Heenan, P.J.5
-
10
-
-
33845496093
-
P53 downstream target genes and tumor suppression: a classical view in evolution
-
10.1038/sj.cdd.4402058, 17068503
-
Rozan LM, El-Deiry WS. p53 downstream target genes and tumor suppression: a classical view in evolution. Cell Death Differ 2007, 14:3-9. 10.1038/sj.cdd.4402058, 17068503.
-
(2007)
Cell Death Differ
, vol.14
, pp. 3-9
-
-
Rozan, L.M.1
El-Deiry, W.S.2
-
11
-
-
0036674617
-
Live or let die: the cell's response to p53
-
10.1038/nrc864, 12154352
-
Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2002, 2:594-604. 10.1038/nrc864, 12154352.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
12
-
-
33646807491
-
Transcriptional regulation by p53: one protein, many possibilities
-
10.1038/sj.cdd.4401916, 16575405
-
Laptenko O, Prives C. Transcriptional regulation by p53: one protein, many possibilities. Cell Death Differ 2006, 13:951-961. 10.1038/sj.cdd.4401916, 16575405.
-
(2006)
Cell Death Differ
, vol.13
, pp. 951-961
-
-
Laptenko, O.1
Prives, C.2
-
13
-
-
18144416611
-
The transcriptional targets of p53 in apoptosis control
-
10.1016/j.bbrc.2005.03.189, 15865941
-
Yu J, Zhang L. The transcriptional targets of p53 in apoptosis control. Biochem Biophys Res Commun 2005, 331:851-858. 10.1016/j.bbrc.2005.03.189, 15865941.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 851-858
-
-
Yu, J.1
Zhang, L.2
-
14
-
-
30344478870
-
A global map of p53 transcription-factor binding sites in the human genome
-
10.1016/j.cell.2005.10.043, 16413492
-
Wei CL, Wu Q, Vega VB, Chiu KP, Ng P, Zhang T, Shahab A, Yong HC, Fu Y, Weng Z, Liu J, Zhao XD, Chew JL, Lee YL, Kuznetsov VA, Sung WK, Miller LD, Lim B, Liu ET, Yu Q, Ng HH, Ruan Y. A global map of p53 transcription-factor binding sites in the human genome. Cell 2006, 124:207-219. 10.1016/j.cell.2005.10.043, 16413492.
-
(2006)
Cell
, vol.124
, pp. 207-219
-
-
Wei, C.L.1
Wu, Q.2
Vega, V.B.3
Chiu, K.P.4
Ng, P.5
Zhang, T.6
Shahab, A.7
Yong, H.C.8
Fu, Y.9
Weng, Z.10
Liu, J.11
Zhao, X.D.12
Chew, J.L.13
Lee, Y.L.14
Kuznetsov, V.A.15
Sung, W.K.16
Miller, L.D.17
Lim, B.18
Liu, E.T.19
Yu, Q.20
Ng, H.H.21
Ruan, Y.22
more..
-
15
-
-
10744226888
-
Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs
-
10.1016/S0092-8674(04)00127-8, 14980218
-
Cawley S, Bekiranov S, Ng HH, Kapranov P, Sekinger EA, Kampa D, Piccolboni A, Sementchenko V, Cheng J, Williams AJ, Wheeler R, Wong B, Drenkow J, Yamanaka M, Patel S, Brubaker S, Tammana H, Helt G, Struhl K, Gingeras TR. Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs. Cell 2004, 116:499-509. 10.1016/S0092-8674(04)00127-8, 14980218.
-
(2004)
Cell
, vol.116
, pp. 499-509
-
-
Cawley, S.1
Bekiranov, S.2
Ng, H.H.3
Kapranov, P.4
Sekinger, E.A.5
Kampa, D.6
Piccolboni, A.7
Sementchenko, V.8
Cheng, J.9
Williams, A.J.10
Wheeler, R.11
Wong, B.12
Drenkow, J.13
Yamanaka, M.14
Patel, S.15
Brubaker, S.16
Tammana, H.17
Helt, G.18
Struhl, K.19
Gingeras, T.R.20
more..
-
16
-
-
41549150851
-
Small molecular weight variants of p53 are expressed in human melanoma cells and are induced by the DNA damaging agent cisplatin
-
10.1158/1078-0432.CCR-07-1422, 18310316
-
Avery-Kiejda KA, Zhang XD, Adams LJ, Scott RJ, Vojtesek B, Lane DP, Hersey P. Small molecular weight variants of p53 are expressed in human melanoma cells and are induced by the DNA damaging agent cisplatin. Clin Cancer Res 2008, 14:1659-1668. 10.1158/1078-0432.CCR-07-1422, 18310316.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1659-1668
-
-
Avery-Kiejda, K.A.1
Zhang, X.D.2
Adams, L.J.3
Scott, R.J.4
Vojtesek, B.5
Lane, D.P.6
Hersey, P.7
-
17
-
-
0042066359
-
Melanoma cells can tolerate high levels of transcriptionally active endogenous p53 but are sensitive to retrovirus-transduced p53
-
10.1038/sj.onc.1206741, 12894234
-
Kichina JV, Rauth S, Das Gupta TK, Gudkov AV. Melanoma cells can tolerate high levels of transcriptionally active endogenous p53 but are sensitive to retrovirus-transduced p53. Oncogene 2003, 22:4911-4917. 10.1038/sj.onc.1206741, 12894234.
-
(2003)
Oncogene
, vol.22
, pp. 4911-4917
-
-
Kichina, J.V.1
Rauth, S.2
Das Gupta, T.K.3
Gudkov, A.V.4
-
18
-
-
0033795383
-
Aberrant regulation and function of wild-type p53 in radioresistant melanoma cells
-
Satyamoorthy K, Chehab NH, Waterman MJ, Lien MC, El-Deiry WS, Herlyn M, Halazonetis TD. Aberrant regulation and function of wild-type p53 in radioresistant melanoma cells. Cell Growth Differ 2000, 11:467-474.
-
(2000)
Cell Growth Differ
, vol.11
, pp. 467-474
-
-
Satyamoorthy, K.1
Chehab, N.H.2
Waterman, M.J.3
Lien, M.C.4
El-Deiry, W.S.5
Herlyn, M.6
Halazonetis, T.D.7
-
19
-
-
0037021660
-
HDM2 protein overexpression and prognosis in primary malignant melanoma
-
Polsky D, Melzer K, Hazan C, Panageas KS, Busam K, Drobnjak M, Kamino H, Spira JG, Kopf AW, Houghton A, Cordon-Cardo C, Osman I. HDM2 protein overexpression and prognosis in primary malignant melanoma. J Natl Cancer Inst 2002, 94:1803-1806.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1803-1806
-
-
Polsky, D.1
Melzer, K.2
Hazan, C.3
Panageas, K.S.4
Busam, K.5
Drobnjak, M.6
Kamino, H.7
Spira, J.G.8
Kopf, A.W.9
Houghton, A.10
Cordon-Cardo, C.11
Osman, I.12
-
20
-
-
34147097875
-
The increased expression of Y box-binding protein 1 in melanoma stimulates proliferation and tumor invasion, antagonizes apoptosis and enhances chemoresistance
-
10.1002/ijc.22512, 17266041
-
Schittek B, Psenner K, Sauer B, Meier F, Iftner T, Garbe C. The increased expression of Y box-binding protein 1 in melanoma stimulates proliferation and tumor invasion, antagonizes apoptosis and enhances chemoresistance. Int J Cancer 2007, 120:2110-2118. 10.1002/ijc.22512, 17266041.
-
(2007)
Int J Cancer
, vol.120
, pp. 2110-2118
-
-
Schittek, B.1
Psenner, K.2
Sauer, B.3
Meier, F.4
Iftner, T.5
Garbe, C.6
-
21
-
-
0013583837
-
Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
-
Zhang XD, Franco A, Myers K, Gray C, Nguyen T, Hersey P. Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res 1999, 59:2747-2753.
-
(1999)
Cancer Res
, vol.59
, pp. 2747-2753
-
-
Zhang, X.D.1
Franco, A.2
Myers, K.3
Gray, C.4
Nguyen, T.5
Hersey, P.6
-
22
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
10.1126/science.1068999, 11910072
-
Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002, 296:550-553. 10.1126/science.1068999, 11910072.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
23
-
-
0031710033
-
A third-generation lentivirus vector with a conditional packaging system
-
110254, 9765382
-
Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, Trono D, Naldini L. A third-generation lentivirus vector with a conditional packaging system. J Virol 1998, 72:8463-8471. 110254, 9765382.
-
(1998)
J Virol
, vol.72
, pp. 8463-8471
-
-
Dull, T.1
Zufferey, R.2
Kelly, M.3
Mandel, R.J.4
Nguyen, M.5
Trono, D.6
Naldini, L.7
-
24
-
-
0034083194
-
Production and concentration of pseudotyped HIV-1-based gene transfer vectors
-
10.1038/sj.gt.3301188, 10849549
-
Reiser J. Production and concentration of pseudotyped HIV-1-based gene transfer vectors. Gene Ther 2000, 7:910-913. 10.1038/sj.gt.3301188, 10849549.
-
(2000)
Gene Ther
, vol.7
, pp. 910-913
-
-
Reiser, J.1
-
25
-
-
79959499775
-
SOURCE
-
SOURCE. , http://smd.stanford.edu/cgi-bin/source/sourceSearch
-
-
-
-
26
-
-
84871629524
-
PANTHER Classification system
-
PANTHER Classification system. , http://www.pantherdb.org
-
-
-
-
27
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
10.1006/meth.2001.1262, 11846609
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408. 10.1006/meth.2001.1262, 11846609.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
28
-
-
35648934994
-
Temozolomide induces senescence but not apoptosis in human melanoma cells
-
10.1038/sj.bjc.6604017, 2360470, 17968428
-
Mhaidat NM, Zhang XD, Allen J, Avery-Kiejda KA, Scott RJ, Hersey P. Temozolomide induces senescence but not apoptosis in human melanoma cells. Br J Cancer 2007, 97:1225-1233. 10.1038/sj.bjc.6604017, 2360470, 17968428.
-
(2007)
Br J Cancer
, vol.97
, pp. 1225-1233
-
-
Mhaidat, N.M.1
Zhang, X.D.2
Allen, J.3
Avery-Kiejda, K.A.4
Scott, R.J.5
Hersey, P.6
-
29
-
-
60749135094
-
Thrombospondin 2 inhibits metastasis of human malignant melanoma through microenvironment-modification in NOD/SCID/gammaCnull (NOG) mice
-
Chijiwa T, Abe Y, Ikoma N, Yamazaki H, Tsukamoto H, Suemizu H, Kawai K, Wakui M, Nishime C, Matsumoto H, Matsuyama M, Mukai M, Ueyama Y, Nakamura M. Thrombospondin 2 inhibits metastasis of human malignant melanoma through microenvironment-modification in NOD/SCID/gammaCnull (NOG) mice. Int J Oncol 2009, 34:5-13.
-
(2009)
Int J Oncol
, vol.34
, pp. 5-13
-
-
Chijiwa, T.1
Abe, Y.2
Ikoma, N.3
Yamazaki, H.4
Tsukamoto, H.5
Suemizu, H.6
Kawai, K.7
Wakui, M.8
Nishime, C.9
Matsumoto, H.10
Matsuyama, M.11
Mukai, M.12
Ueyama, Y.13
Nakamura, M.14
-
30
-
-
0028089956
-
Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines
-
10.1002/ijc.2910590209, 7927918
-
Zabrenetzky V, Harris CC, Steeg PS, Roberts DD. Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines. Int J Cancer 1994, 59:191-195. 10.1002/ijc.2910590209, 7927918.
-
(1994)
Int J Cancer
, vol.59
, pp. 191-195
-
-
Zabrenetzky, V.1
Harris, C.C.2
Steeg, P.S.3
Roberts, D.D.4
-
31
-
-
36048965904
-
Down-regulation of surface fractalkine by RNA interference in B16 melanoma reduced tumor growth in mice
-
10.1016/j.bbrc.2007.10.124, 17971299
-
Ren T, Chen Q, Tian Z, Wei H. Down-regulation of surface fractalkine by RNA interference in B16 melanoma reduced tumor growth in mice. Biochem Biophys Res Commun 2007, 364:978-984. 10.1016/j.bbrc.2007.10.124, 17971299.
-
(2007)
Biochem Biophys Res Commun
, vol.364
, pp. 978-984
-
-
Ren, T.1
Chen, Q.2
Tian, Z.3
Wei, H.4
-
32
-
-
78049284499
-
P53 Prevents progression of nevi to melanoma predominantly through cell cycle regulation
-
10.1111/j.1755-148X.2010.00773.x, 20849464
-
Terzian T, Torchia EC, Dai D, Robinson SE, Murao K, Stiegmann RA, Gonzalez V, Boyle GM, Powell MB, Pollock PM, Lozano G, Robinson WA, Roop DR, Box NF. p53 Prevents progression of nevi to melanoma predominantly through cell cycle regulation. Pigment Cell Melanoma Res 2010, 23:781-794. 10.1111/j.1755-148X.2010.00773.x, 20849464.
-
(2010)
Pigment Cell Melanoma Res
, vol.23
, pp. 781-794
-
-
Terzian, T.1
Torchia, E.C.2
Dai, D.3
Robinson, S.E.4
Murao, K.5
Stiegmann, R.A.6
Gonzalez, V.7
Boyle, G.M.8
Powell, M.B.9
Pollock, P.M.10
Lozano, G.11
Robinson, W.A.12
Roop, D.R.13
Box, N.F.14
-
33
-
-
0036606349
-
An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli
-
10.1093/nar/30.11.2398, 117192, 12034827
-
Hashimoto Y, Zhang C, Kawauchi J, Imoto I, Adachi MT, Inazawa J, Amagasa T, Hai T, Kitajima S. An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli. Nucleic Acids Res 2002, 30:2398-2406. 10.1093/nar/30.11.2398, 117192, 12034827.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 2398-2406
-
-
Hashimoto, Y.1
Zhang, C.2
Kawauchi, J.3
Imoto, I.4
Adachi, M.T.5
Inazawa, J.6
Amagasa, T.7
Hai, T.8
Kitajima, S.9
-
34
-
-
67049168909
-
The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes
-
10.2353/ajpath.2009.081057, 2684200, 19389934
-
Yu H, McDaid R, Lee J, Possik P, Li L, Kumar SM, Elder DE, Van Belle P, Gimotty P, Guerra M, Hammond R, Nathanson KL, Dalla Palma M, Herlyn M, Xu X. The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes. Am J Pathol 2009, 174:2367-2377. 10.2353/ajpath.2009.081057, 2684200, 19389934.
-
(2009)
Am J Pathol
, vol.174
, pp. 2367-2377
-
-
Yu, H.1
McDaid, R.2
Lee, J.3
Possik, P.4
Li, L.5
Kumar, S.M.6
Elder, D.E.7
Van Belle, P.8
Gimotty, P.9
Guerra, M.10
Hammond, R.11
Nathanson, K.L.12
Dalla Palma, M.13
Herlyn, M.14
Xu, X.15
-
35
-
-
0038182453
-
A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein
-
10.1093/emboj/cdg274, 156770, 12773400
-
Foray N, Marot D, Gabriel A, Randrianarison V, Carr AM, Perricaudet M, Ashworth A, Jeggo P. A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein. Embo J 2003, 22:2860-2871. 10.1093/emboj/cdg274, 156770, 12773400.
-
(2003)
Embo J
, vol.22
, pp. 2860-2871
-
-
Foray, N.1
Marot, D.2
Gabriel, A.3
Randrianarison, V.4
Carr, A.M.5
Perricaudet, M.6
Ashworth, A.7
Jeggo, P.8
-
36
-
-
3843066731
-
BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage
-
10.1074/jbc.M405372200, 15159397
-
Fabbro M, Savage K, Hobson K, Deans AJ, Powell SN, McArthur GA, Khanna KK. BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage. J Biol Chem 2004, 279:31251-31258. 10.1074/jbc.M405372200, 15159397.
-
(2004)
J Biol Chem
, vol.279
, pp. 31251-31258
-
-
Fabbro, M.1
Savage, K.2
Hobson, K.3
Deans, A.J.4
Powell, S.N.5
McArthur, G.A.6
Khanna, K.K.7
-
37
-
-
34248185454
-
P53: guardian of the genome and policeman of the oncogenes
-
10.4161/cc.6.9.4211, 17457049
-
Efeyan A, Serrano M. p53: guardian of the genome and policeman of the oncogenes. Cell Cycle 2007, 6:1006-1010. 10.4161/cc.6.9.4211, 17457049.
-
(2007)
Cell Cycle
, vol.6
, pp. 1006-1010
-
-
Efeyan, A.1
Serrano, M.2
-
38
-
-
18344377030
-
The p53 pathway: positive and negative feedback loops
-
10.1038/sj.onc.1208615, 15838523
-
Harris SL, Levine AJ. The p53 pathway: positive and negative feedback loops. Oncogene 2005, 24:2899-2908. 10.1038/sj.onc.1208615, 15838523.
-
(2005)
Oncogene
, vol.24
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
39
-
-
0038819652
-
The INK4a/ARF locus and melanoma
-
10.1038/sj.onc.1206461, 12789286
-
Sharpless E, Chin L. The INK4a/ARF locus and melanoma. Oncogene 2003, 22:3092-3098. 10.1038/sj.onc.1206461, 12789286.
-
(2003)
Oncogene
, vol.22
, pp. 3092-3098
-
-
Sharpless, E.1
Chin, L.2
-
40
-
-
35948959024
-
The universal character of the tumor-associated antigen survivin
-
10.1158/1078-0432.CCR-07-0686, 17947459
-
Andersen MH, Svane IM, Becker JC, Straten PT. The universal character of the tumor-associated antigen survivin. Clin Cancer Res 2007, 13:5991-5994. 10.1158/1078-0432.CCR-07-0686, 17947459.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5991-5994
-
-
Andersen, M.H.1
Svane, I.M.2
Becker, J.C.3
Straten, P.T.4
-
41
-
-
38849209818
-
Survivin repression by p53, Rb and E2F2 in normal human melanocytes
-
2292458, 17916908
-
Raj D, Liu T, Samadashwily G, Li F, Grossman D. Survivin repression by p53, Rb and E2F2 in normal human melanocytes. Carcinogenesis 2008, 29:194-201. 2292458, 17916908.
-
(2008)
Carcinogenesis
, vol.29
, pp. 194-201
-
-
Raj, D.1
Liu, T.2
Samadashwily, G.3
Li, F.4
Grossman, D.5
-
42
-
-
78049243108
-
Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis
-
10.1111/j.1755-148X.2010.00752.x, 20718941
-
Ferguson B, Konrad Muller H, Handoko HY, Khosrotehrani K, Beermann F, Hacker E, Peter Soyer H, Bosenberg M, Walker GJ. Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis. Pigment Cell Melanoma Res 2010, 23:771-780. 10.1111/j.1755-148X.2010.00752.x, 20718941.
-
(2010)
Pigment Cell Melanoma Res
, vol.23
, pp. 771-780
-
-
Ferguson, B.1
Konrad Muller, H.2
Handoko, H.Y.3
Khosrotehrani, K.4
Beermann, F.5
Hacker, E.6
Peter Soyer, H.7
Bosenberg, M.8
Walker, G.J.9
-
43
-
-
33846148980
-
Outcomes of p53 activation--spoilt for choice
-
10.1242/jcs.03293, 17158908
-
Vousden KH. Outcomes of p53 activation--spoilt for choice. J Cell Sci 2006, 119:5015-5020. 10.1242/jcs.03293, 17158908.
-
(2006)
J Cell Sci
, vol.119
, pp. 5015-5020
-
-
Vousden, K.H.1
-
44
-
-
44049092395
-
The dark side of a tumor suppressor: anti-apoptotic p53
-
10.1038/cdd.2008.33, 18356920
-
Janicke RU, Sohn D, Schulze-Osthoff K. The dark side of a tumor suppressor: anti-apoptotic p53. Cell Death Differ 2008, 15:959-976. 10.1038/cdd.2008.33, 18356920.
-
(2008)
Cell Death Differ
, vol.15
, pp. 959-976
-
-
Janicke, R.U.1
Sohn, D.2
Schulze-Osthoff, K.3
-
45
-
-
0030026934
-
Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis
-
10.1038/nm0196-72, 8564846
-
Wahl AF, Donaldson KL, Fairchild C, Lee FY, Foster SA, Demers GW, Galloway DA. Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis. Nat Med 1996, 2:72-79. 10.1038/nm0196-72, 8564846.
-
(1996)
Nat Med
, vol.2
, pp. 72-79
-
-
Wahl, A.F.1
Donaldson, K.L.2
Fairchild, C.3
Lee, F.Y.4
Foster, S.A.5
Demers, G.W.6
Galloway, D.A.7
-
46
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
10.1172/JCI6863, 408422, 10430607
-
Bunz F, Hwang PM, Torrance C, Waldman T, Zhang Y, Dillehay L, Williams J, Lengauer C, Kinzler KW, Vogelstein B. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J Clin Invest 1999, 104:263-269. 10.1172/JCI6863, 408422, 10430607.
-
(1999)
J Clin Invest
, vol.104
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
Waldman, T.4
Zhang, Y.5
Dillehay, L.6
Williams, J.7
Lengauer, C.8
Kinzler, K.W.9
Vogelstein, B.10
-
47
-
-
0030021996
-
Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents
-
Hawkins DS, Demers GW, Galloway DA. Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents. Cancer Res 1996, 56:892-898.
-
(1996)
Cancer Res
, vol.56
, pp. 892-898
-
-
Hawkins, D.S.1
Demers, G.W.2
Galloway, D.A.3
-
48
-
-
0028901034
-
Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline
-
Fan S, Smith ML, Rivet DJ, Duba D, Zhan Q, Kohn KW, Fornace AJ, O'Connor PM. Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline. Cancer Res 1995, 55:1649-1654.
-
(1995)
Cancer Res
, vol.55
, pp. 1649-1654
-
-
Fan, S.1
Smith, M.L.2
Rivet, D.J.3
Duba, D.4
Zhan, Q.5
Kohn, K.W.6
Fornace, A.J.7
O'Connor, P.M.8
-
49
-
-
30444457740
-
Knock down of p53 levels in human keratinocytes increases susceptibility to type I and type II interferon-induced apoptosis mediated by a TRAIL dependent pathway
-
10.1016/j.jdermsci.2005.10.003, 16289694
-
Chaturvedi V, Bodner B, Qin JZ, Nickoloff BJ. Knock down of p53 levels in human keratinocytes increases susceptibility to type I and type II interferon-induced apoptosis mediated by a TRAIL dependent pathway. J Dermatol Sci 2006, 41:31-41. 10.1016/j.jdermsci.2005.10.003, 16289694.
-
(2006)
J Dermatol Sci
, vol.41
, pp. 31-41
-
-
Chaturvedi, V.1
Bodner, B.2
Qin, J.Z.3
Nickoloff, B.J.4
-
50
-
-
24044494290
-
Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis
-
10.1038/sj.onc.1208650, 15940268
-
Chaturvedi V, Sitailo LA, Qin JZ, Bodner B, Denning MF, Curry J, Zhang W, Brash D, Nickoloff BJ. Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis. Oncogene 2005, 24:5299-5312. 10.1038/sj.onc.1208650, 15940268.
-
(2005)
Oncogene
, vol.24
, pp. 5299-5312
-
-
Chaturvedi, V.1
Sitailo, L.A.2
Qin, J.Z.3
Bodner, B.4
Denning, M.F.5
Curry, J.6
Zhang, W.7
Brash, D.8
Nickoloff, B.J.9
-
51
-
-
28644447272
-
The antioxidant function of the p53 tumor suppressor
-
10.1038/nm1320, 2637821, 16286925
-
Sablina AA, Budanov AV, Ilyinskaya GV, Agapova LS, Kravchenko JE, Chumakov PM. The antioxidant function of the p53 tumor suppressor. Nat Med 2005, 11:1306-1313. 10.1038/nm1320, 2637821, 16286925.
-
(2005)
Nat Med
, vol.11
, pp. 1306-1313
-
-
Sablina, A.A.1
Budanov, A.V.2
Ilyinskaya, G.V.3
Agapova, L.S.4
Kravchenko, J.E.5
Chumakov, P.M.6
-
52
-
-
27744547091
-
Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma
-
10.1016/j.cell.2005.09.029, 16286009
-
Wu WS, Heinrichs S, Xu D, Garrison SP, Zambetti GP, Adams JM, Look AT. Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma. Cell 2005, 123:641-653. 10.1016/j.cell.2005.09.029, 16286009.
-
(2005)
Cell
, vol.123
, pp. 641-653
-
-
Wu, W.S.1
Heinrichs, S.2
Xu, D.3
Garrison, S.P.4
Zambetti, G.P.5
Adams, J.M.6
Look, A.T.7
-
53
-
-
16844387097
-
Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas
-
10.1158/0008-5472.CAN-04-3045, 15781639
-
Vance KW, Carreira S, Brosch G, Goding CR. Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas. Cancer Res 2005, 65:2260-2268. 10.1158/0008-5472.CAN-04-3045, 15781639.
-
(2005)
Cancer Res
, vol.65
, pp. 2260-2268
-
-
Vance, K.W.1
Carreira, S.2
Brosch, G.3
Goding, C.R.4
-
54
-
-
69949171557
-
P53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence
-
10.1038/ncb1928, 2802853, 19701195
-
Fujita K, Mondal AM, Horikawa I, Nguyen GH, Kumamoto K, Sohn JJ, Bowman ED, Mathe EA, Schetter AJ, Pine SR, Ji H, Vojtesek B, Bourdon JC, Lane DP, Harris CC. p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence. Nat Cell Biol 2009, 11:1135-1142. 10.1038/ncb1928, 2802853, 19701195.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1135-1142
-
-
Fujita, K.1
Mondal, A.M.2
Horikawa, I.3
Nguyen, G.H.4
Kumamoto, K.5
Sohn, J.J.6
Bowman, E.D.7
Mathe, E.A.8
Schetter, A.J.9
Pine, S.R.10
Ji, H.11
Vojtesek, B.12
Bourdon, J.C.13
Lane, D.P.14
Harris, C.C.15
-
55
-
-
4944255743
-
Post-translational modification of p53 in tumorigenesis
-
10.1038/nrc1455, 15510160
-
Bode AM, Dong Z. Post-translational modification of p53 in tumorigenesis. Nat Rev Cancer 2004, 4:793-805. 10.1038/nrc1455, 15510160.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 793-805
-
-
Bode, A.M.1
Dong, Z.2
-
56
-
-
0035821648
-
Distinct pattern of p53 phosphorylation in human tumors
-
10.1038/sj.onc.1204458, 11423984
-
Minamoto T, Buschmann T, Habelhah H, Matusevich E, Tahara H, Boerresen-Dale AL, Harris C, Sidransky D, Ronai Z. Distinct pattern of p53 phosphorylation in human tumors. Oncogene 2001, 20:3341-3347. 10.1038/sj.onc.1204458, 11423984.
-
(2001)
Oncogene
, vol.20
, pp. 3341-3347
-
-
Minamoto, T.1
Buschmann, T.2
Habelhah, H.3
Matusevich, E.4
Tahara, H.5
Boerresen-Dale, A.L.6
Harris, C.7
Sidransky, D.8
Ronai, Z.9
-
57
-
-
33845204856
-
Repression of p53 activity by Smyd2-mediated methylation
-
10.1038/nature05287, 17108971
-
Huang J, Perez-Burgos L, Placek BJ, Sengupta R, Richter M, Dorsey JA, Kubicek S, Opravil S, Jenuwein T, Berger SL. Repression of p53 activity by Smyd2-mediated methylation. Nature 2006, 444:629-632. 10.1038/nature05287, 17108971.
-
(2006)
Nature
, vol.444
, pp. 629-632
-
-
Huang, J.1
Perez-Burgos, L.2
Placek, B.J.3
Sengupta, R.4
Richter, M.5
Dorsey, J.A.6
Kubicek, S.7
Opravil, S.8
Jenuwein, T.9
Berger, S.L.10
-
58
-
-
35748961986
-
P53 enters the microRNA world
-
10.1016/j.ccr.2007.10.028, 17996645
-
Hermeking H. p53 enters the microRNA world. Cancer Cell 2007, 12:414-418. 10.1016/j.ccr.2007.10.028, 17996645.
-
(2007)
Cancer Cell
, vol.12
, pp. 414-418
-
-
Hermeking, H.1
|