Down-regulation of surface fractalkine by RNA interference in B16 melanoma reduced tumor growth in mice

Biochemical and Biophysical Research Communications

Volumn 364, Issue 4, 2007, Pages 978-984

  Ren, Tong ^a   Chen, Qingfeng ^a   Tian, Zhigang ^a   Wei, Haiming ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Adenovirus; CX3CL1; Melanoma; RNA interference; Tumorigenesis

Indexed keywords

CX3C CHEMOKINE; FRACTALKINE; SMALL INTERFERING RNA;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DOWN REGULATION; MELANOMA B16; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; TUMOR GROWTH; TUMOR VASCULARIZATION;

ANIMALS; CELL LINE, TUMOR; CELL MEMBRANE; CELL PROLIFERATION; CHEMOKINE CX3CL1; DOWN-REGULATION; FEMALE; GENE SILENCING; GENE THERAPY; MELANOMA; MICE; MICE, INBRED C57BL; RNA INTERFERENCE;

ADENOVIRIDAE; MUS;

EID: 36048965904     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.10.124     Document Type: Article

References (29)

1. Arenberg D.A., Kunkel S.L., Polverini P.J., Glass M., Burdick M.D., and Strieter R.M. Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice. J. Clin. Invest. 97 (1996) 2792-2802
2. Muller A., Homey B., Soto H., Ge N., Catron D., Buchanan M.E., McClanahan T., Murphy E., Yuan W., Wagner S.N., Barrera J.L., Mohar A., Verastegui E., and Zlotnik A. Involvement of chemokine receptors in breast cancer metastasis. Nature 410 (2001) 50-56
3. Strieter R.M., Polverini P.J., Kunkel S.L., Arenberg D.A., Burdick M.D., Kasper J., Dzuiba J., Van Damme J., Walz A., Marriott D., et al. The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J. Biol. Chem. 270 (1995) 27348-27357
4. Weber K.S., Nelson P.J., Grone H.J., and Weber C. Expression of CCR2 by endothelial cells: implications for MCP-1 mediated wound injury repair and In vivo inflammatory activation of endothelium. Arterioscler Thromb. Vasc. Biol. 19 (1999) 2085-2093
5. Goede V., Brogelli L., Ziche M., and Augustin H.G. Induction of inflammatory angiogenesis by monocyte chemoattractant protein-1. Int. J. Cancer 82 (1999) 765-770
6. Boshoff C., Endo Y., Collins P.D., Takeuchi Y., Reeves J.D., Schweickart V.L., Siani M.A., Sasaki T., Williams T.J., Gray P.W., Moore P.S., Chang Y., and Weiss R.A. Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokines. Science 278 (1997) 290-294
7. Bazan J.F., Bacon K.B., Hardiman G., Wang W., Soo K., Rossi D., Greaves D.R., Zlotnik A., and Schall T.J. A new class of membrane-bound chemokine with a CX3C motif. Nature 385 (1997) 640-644
8. Imai T., Hieshima K., Haskell C., Baba M., Nagira M., Nishimura M., Kakizaki M., Takagi S., Nomiyama H., Schall T.J., and Yoshie O. Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell 91 (1997) 521-530
9. Zhang X., Wei H., Chen Q., and Tian Z. Activation of human natural killer cells by recombinant membrane-expressed fractalkine on the surface of tumor cells. Oncol. Rep. 17 (2007) 1371-1375
10. Matsubara T., Ono T., Yamanoi A., Tachibana M., and Nagasue N. Fractalkine-CX3CR1 axis regulates tumor cell cycle and deteriorates prognosis after radical resection for hepatocellular carcinoma. J. Surg. Oncol. 95 (2007) 241-249
11. Haskell C.A., Cleary M.D., and Charo I.F. Molecular uncoupling of fractalkine-mediated cell adhesion and signal transduction. Rapid flow arrest of CX3CR1-expressing cells is independent of G-protein activation. J. Biol. Chem. 274 (1999) 10053-10058
12. Fong A.M., Robinson L.A., Steeber D.A., Tedder T.F., Yoshie O., Imai T., and Patel D.D. Fractalkine and CX3CR1 mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow. J. Exp. Med. 188 (1998) 1413-1419
13. Hundhausen C., Misztela D., Berkhout T.A., Broadway N., Saftig P., Reiss K., Hartmann D., Fahrenholz F., Postina R., Matthews V., Kallen K.J., Rose-John S., and Ludwig A. The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion. Blood 102 (2003) 1186-1195
14. Fong A.M., Alam S.M., Imai T., Haribabu B., and Patel D.D. CX3CR1 tyrosine sulfation enhances fractalkine-induced cell adhesion. J. Biol. Chem. 277 (2002) 19418-19423
15. Goda S., Imai T., Yoshie O., Yoneda O., Inoue H., Nagano Y., Okazaki T., Imai H., Bloom E.T., Domae N., and Umehara H. CX3C-chemokine, fractalkine-enhanced adhesion of THP-1 cells to endothelial cells through integrin-dependent and -independent mechanisms. J. Immunol. 164 (2000) 4313-4320
16. Ancuta P., Rao R., Moses A., Mehle A., Shaw S.K., Luscinskas F.W., and Gabuzda D. Fractalkine preferentially mediates arrest and migration of CD16+ monocytes. J. Exp. Med. 197 (2003) 1701-1707
17. Lauro C., Catalano M., Trettel F., Mainiero F., Ciotti M.T., Eusebi F., and Limatola C. The chemokine CX3CL1 reduces migration and increases adhesion of neurons with mechanisms dependent on the beta1 integrin subunit. J. Immunol. 177 (2006) 7599-7606
18. Xin H., Kikuchi T., Andarini S., Ohkouchi S., Suzuki T., Nukiwa T., Huqun, Hagiwara K., Honjo T., and Saijo Y. Antitumor immune response by CX3CL1 fractalkine gene transfer depends on both NK and T cells. Eur. J. Immunol. 35 (2005) 1371-1380
19. Tang L., Hu H.D., Hu P., Lan Y.H., Peng M.L., Chen M., and Ren H. Gene therapy with CX3CL1/Fractalkine induces antitumor immunity to regress effectively mouse hepatocellular carcinoma. Gene Ther. 14 (2007) 1226-1234
20. Moore B.B., Arenberg D.A., Addison C.L., Keane M.P., Polverini P.J., and Strieter R.M. CXC chemokines mechanism of action in regulating tumor angiogenesis. Angiogenesis 2 (1998) 123-134
21. Moore B.B., Arenberg D.A., Addison C.L., Keane M.P., and Strieter R.M. Tumor angiogenesis is regulated by CXC chemokines. J. Lab. Clin. Med. 132 (1998) 97-103
22. Feil C., and Augustin H.G. Endothelial cells differentially express functional CXC-chemokine receptor-4 (CXCR-4/fusin) under the control of autocrine activity and exogenous cytokines. Biochem. Biophys. Res. Commun. 247 (1998) 38-45
23. Volin M.V., Woods J.M., Amin M.A., Connors M.A., Harlow L.A., and Koch A.E. Fractalkine: a novel angiogenic chemokine in rheumatoid arthritis. Am. J. Pathol. 159 (2001) 1521-1530
24. Harrison J.K., Fong A.M., Swain P.A., Chen S., Yu Y.R., Salafranca M.N., Greenleaf W.B., Imai T., and Patel D.D. Mutational analysis of the fractalkine chemokine domain. Basic amino acid residues differentially contribute to CX3CR1 binding, signaling, and cell adhesion. J. Biol. Chem. 276 (2001) 21632-21641
25. Harrison J.K., Jiang Y., Chen S., Xia Y., Maciejewski D., McNamara R.K., Streit W.J., Salafranca M.N., Adhikari S., Thompson D.A., Botti P., Bacon K.B., and Feng L. Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia. Proc. Natl. Acad. Sci. USA 95 (1998) 10896-10901
26. Yoneda O., Imai T., Goda S., Inoue H., Yamauchi A., Okazaki T., Imai H., Yoshie O., Bloom E.T., Domae N., and Umehara H. Fractalkine-mediated endothelial cell injury by NK cells. J. Immunol. 164 (2000) 4055-4062
27. Zhang X., Wei H., Wang H., and Tian Z. Involvement of interaction between Fractalkine and CX3CR1 in cytotoxicity of natural killer cells against tumor cells. Oncol. Rep. 15 (2006) 485-488
28. Efsen E., Grappone C., DeFranco R.M., Milani S., Romanelli R.G., Bonacchi A., Caligiuri A., Failli P., Annunziato F., Pagliai G., Pinzani M., Laffi G., Gentilini P., and Marra F. Up-regulated expression of fractalkine and its receptor CX3CR1 during liver injury in humans. J. Hepatol. 37 (2002) 39-47
29. Ohta M., Tanaka F., Yamaguchi H., Sadanaga N., Inoue H., and Mori M. The high expression of fractalkine results in a better prognosis for colorectal cancer patients. Int. J. Oncol. 26 (2005) 41-47