EMMPRIN and its ligand cyclophilin A regulate MT1-MMP, MMP-9 and M-CSF during foam cell formation

Atherosclerosis

Volumn 209, Issue 1, 2010, Pages 51-57

  Seizer, Peter ^a   Schönberger, Tanja ^a   Schött, Moritz ^a   R Lang, Michael ^a   Langer, Harald F ^a   Bigalke, Boris ^a   Krämer, Björn F ^a   Borst, Oliver ^a   Daub, Karin ^a   Heidenreich, Olaf ^b   Schmidt, Roland ^c   Lindemann, Stephan ^a   Herouy, Yared ^d   Gawaz, Meinrad ^a   May, Andreas E ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Atherosclerosis; CD34+ progenitor cells; Cyclophylin A; EMMPRIN; Foam cells; MMPs

Indexed keywords

CD147 ANTIGEN; CD34 ANTIGEN; COLONY STIMULATING FACTOR 1; CYCLOPHILIN A; CYCLOSPORIN A [4 N METHYLISOLEUCINE]; GELATINASE B; MATRIX METALLOPROTEINASE 14; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; CELL DIFFERENTIATION; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME RELEASE; FOAM CELL; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; SUPERNATANT; THROMBOCYTE; UPREGULATION;

ANIMALS; ANTIGENS, CD147; ANTIGENS, CD34; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CELL DIFFERENTIATION; CELL MOVEMENT; COLLAGEN; CYCLOPHILIN A; CYCLOSPORINE; DRUG COMBINATIONS; FOAM CELLS; HUMANS; LAMININ; LIGANDS; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 9; MICE; MICE, MUTANT STRAINS; PROTEOGLYCANS; STEM CELLS;

EID: 77049117972     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.08.029     Document Type: Article

References (36)

1. Shashkin P., Dragulev B., and Ley K. Macrophage differentiation to foam cells. Curr Pharm Des 11 23 (2005) 3061-3072
2. Moreno P.R., Falk E., Palacios I.F., et al. Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture. Circulation 90 2 (1994) 775-778
3. Hristov M., Erl W., and Weber P.C. Endothelial progenitor cells: mobilization, differentiation, and homing. Arterioscler Thromb Vasc Biol 23 July (7) (2003) 1185-1189
4. Daub K., Langer H., Seizer P., et al. Platelets induce differentiation of human CD34+ progenitor cells into foam cells and endothelial cells. FASEB J 20 14 (2006) 2559-2561
5. Langer H., May A.E., Daub K., et al. Adherent platelets recruit and induce differentiation of murine embryonic endothelial progenitor cells to mature endothelial cells in vitro. Circ Res 98 February (2) (2006) e2-e10
6. Stellos K., Langer H., Daub K., et al. Platelet-derived stromal cell-derived factor-1 regulates adhesion and promotes differentiation of human CD34+ cells to endothelial progenitor cells. Circulation 117 January (2) (2008) 206-215
7. Zampetaki A., Kirton J.P., and Xu Q. Vascular repair by endothelial progenitor cells. Cardiovasc Res 78 June (3) (2008) 413-421
8. Brown D.L., Hibbs M.S., Kearney M., Loushin C., and Isner J.M. Identification of 92-kD gelatinase in human coronary atherosclerotic lesions. Association of active enzyme synthesis with unstable angina. Circulation 91 April (8) (1995) 2125-2131
9. Schmidt R., Bultmann A., Ungerer M., et al. Extracellular matrix metalloproteinase inducer regulates Matrix MetalloProteinase activity in cardiovascular cells: implications in acute myocardial infarction. Circulation 113 February (6) (2006) 834-841
10. Toole B.P. Emmprin (CD147), a cell surface regulator of Matrix MetalloProteinase production and function. Curr Top Dev Biol 54 (2003) 371-389
11. Li R., Huang L., Guo H., and Toole B.P. Basigin (murine EMMPRIN) stimulates Matrix MetalloProteinase production by fibroblasts. J Cell Physiol 186 3 (2001) 371-379
12. Sun J., and Hemler M.E. Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions. Cancer Res 61 March (5) (2001) 2276-2281
13. Schmidt R., Bultmann A., Fischel S., et al. Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor {kappa}B dependent inflammation in monocytes. Circ Res 102 November (3) (2008) 302-309
14. Yurchenko V., Constant S., and Bukrinsky M. Dealing with the family: CD147 interactions with cyclophilins. Immunology 117 3 (2006) 301-309
15. Yurchenko V., O'Connor M., Dai W.W., et al. CD147 is a signaling receptor for cyclophilin B. Biochem Biophys Res Commun 288 November (4) (2001) 786-788
16. Jin Z.G., Melaragno M.G., Liao D.F., et al. Cyclophilin A is a secreted growth factor induced by oxidative stress. Circ Res 87 October (9) (2000) 789-796
17. Sherry B., Yarlett N., Strupp A., and Cerami A. Identification of cyclophilin as a proinflammatory secretory product of lipopolysaccharide-activated macrophages. Proc Natl Acad Sci U S A 89 April (8) (1992) 3511-3515
18. Seko Y., Fujimura T., Taka H., et al. Hypoxia followed by reoxygenation induces secretion of cyclophilin A from cultured rat cardiac myocytes. Biochem Biophys Res Commun 317 April (1) (2004) 162-168
19. Major T.C., Liang L., Lu X., Rosebury W., and Bocan T.M. Extracellular matrix metalloproteinase inducer (EMMPRIN) is induced upon monocyte differentiation and is expressed in human atheroma. Arterioscler Thromb Vasc Biol 22 July (7) (2002) 1200-1207
20. Coppinger J.A., Cagney G., Toomey S., et al. Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood 103 March (6) (2004) 2096-2104
21. May A.E., Schmidt R., Bulbul B.O., et al. Plasminogen and Matrix MetalloProteinase activation by enzymatically modified low density lipoproteins in monocytes and smooth muscle cells. Thromb Haemost 93 4 (2005) 710-715
22. Brach M.A., Henschler R., Mertelsmann R.H., and Herrmann F. Regulation of M-CSF expression by M-CSF: role of protein kinase C and transcription factor NF kappa B. Pathobiology 59 4 (1991) 284-288
23. Brach M.A., Arnold C., Kiehntopf M., Gruss H.J., and Herrmann F. Transcriptional activation of the macrophage colony-stimulating factor gene by IL-2 is associated with secretion of bioactive macrophage colony-stimulating factor protein by monocytes and involves activation of the transcription factor NF-kappa B. J Immunol 150 June (12) (1993) 5535-5543
24. Hohensinner P.J., Kaun C., Rychli K., et al. Macrophage colony stimulating factor expression in human cardiac cells is upregulated by tumor necrosis factor-alpha via an NF-kappaB dependent mechanism. J Thromb Haemost 5 12 (2007) 2520-2528
25. Rajavashisth T.B., Yamada H., and Mishra N.K. Transcriptional activation of the macrophage-colony stimulating factor gene by minimally modified LDL. Involvement of nuclear factor-kappa B. Arterioscler Thromb Vasc Biol 15 10 (1995) 1591-1598
26. Devaraj S., Yun J.M., Duncan-Staley C., and Jialal I. C-reactive protein induces M-CSF release and macrophage proliferation. J Leukoc Biol 85 2 (2009) 262-267
27. Gawaz M., Stellos K., and Langer H.F. Platelets modulate atherogenesis and progression of atherosclerotic plaques via interaction with progenitor and dendritic cells. J Thromb Haemost 6 2 (2008) 235-242
28. Lusis A.J. Atherosclerosis. Nature 407 September (6801) (2000) 233-241
29. Libby P., Ridker P.M., and Maseri A. Inflammation and atherosclerosis. Circulation 105 March (9) (2002) 1135-1143
30. Zhang J., Ge H., Wang C., et al. Inhibitory effect of PPAR on the expression of EMMPRIN in macrophages and foam cells. Int J Cardiol 117 May (3) (2007) 373-380
31. Galat A. Peptidylproline cis-trans-isomerases: immunophilins. Eur J Biochem 216 September (3) (1993) 689-707
32. Tegeder I., Schumacher A., John S., et al. Elevated serum cyclophilin levels in patients with severe sepsis. J Clin Immunol 17 5 (1997) 380-386
33. Billich A., Winkler G., Aschauer H., Rot A., and Peichl P. Presence of cyclophilin A in synovial fluids of patients with rheumatoid arthritis. J Exp Med 185 March (5) (1997) 975-980
34. Johnson J.L., Baker A.H., Oka K., et al. Suppression of atherosclerotic plaque progression and instability by tissue inhibitor of metalloproteinase-2: involvement of macrophage migration and apoptosis. Circulation 113 May (20) (2006) 2435-2444
35. Tang Y., Nakada M.T., Kesavan P., et al. Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and Matrix MetalloProteinases. Cancer Res 65 April (8) (2005) 3193-3199
36. Dimmeler S., Burchfield J., and Zeiher A.M. Cell-based therapy of myocardial infarction. Arterioscler Thromb Vasc Biol 28 2 (2008) 208-216