Modulation of retinal blood flow by kinin B1 receptor in Streptozotocin-diabetic rats

Experimental Eye Research

Volumn 92, Issue 6, 2011, Pages 482-489

  Pouliot, Mylène ^a   Hétu, Simon ^a   Lahjouji, Karim ^a   Couture, Réjean ^a   Vaucher, Elvire ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Autoradiography; B1 receptor; Blood flow; Diabetes; Kinins; Retina

Indexed keywords

BRADYKININ B1 RECEPTOR; BRADYKININ B1 RECEPTOR ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; MALE; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; REGULATORY MECHANISM; RETINA BLOOD FLOW; STREPTOZOCIN DIABETES; WAKEFULNESS; WESTERN BLOTTING;

ANIMALS; AUTORADIOGRAPHY; BLOOD FLOW VELOCITY; BLOTTING, WESTERN; CEREBROVASCULAR CIRCULATION; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; DIOXOLES; FLUORESCEIN ANGIOGRAPHY; MALE; RATS; RATS, WISTAR; RECEPTOR, BRADYKININ B1; REGIONAL BLOOD FLOW; RETINAL VESSELS; SULFONAMIDES; UP-REGULATION;

EID: 79956374364     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2011.03.007     Document Type: Article

References (67)

1. Abdouh M., Khanjari A., Abdelazziz N., Ongali B., Couture R., Hassessian H.M. Early upregulation of kinin B1 receptors in retinal microvessels of the streptozotocin-diabetic rat. Br. J. Pharmacol. 2003, 140:33-40.
2. Abdouh M., Talbot S., Couture R., Hassessian H.M. Retinal plasma extravasation in streptozotocin-diabetic rats mediated by kinin B(1) and B(2) receptors. Br. J. Pharmacol. 2008, 154:136-143.
3. Ahluwalia A., Perretti M. B1 receptors as a new inflammatory target. Could this B the 1?. Trends Pharmacol. Sci. 1999, 20:100-104.
4. Alder V.A., Su E.N., Yu D.Y., Cringle S., Yu P. Overview of studies on metabolic and vascular regulatory changes in early diabetic retinopathy. Aust. N.Z. J. Ophthalmol. 1998, 26:141-148.
5. Bader M., Bohnemeier H., Zollmann F.S., Lockley-Jones O.E., Ganten D. Transgenic animals in cardiovascular disease research. Exp. Physiol. 2000, 85:713-731.
6. Buleon M., Allard J., Jaafar A., Praddaude F., Dickson Z., Ranera M.T., Pecher C., Girolami J.P., Tack I. Pharmacological blockade of B2-kinin receptor reduces renal protective effect of angiotensin-converting enzyme inhibition in db/db mice model. Am. J. Physiol. Renal Physiol. 2008, 294:F1249-F1256.
7. Bursell S.E., Clermont A.C., Kinsley B.T., Simonson D.C., Aiello L.M., Wolpert H.A. Retinal blood flow changes in patients with insulin-dependent diabetes mellitus and no diabetic retinopathy. Invest. Ophthalmol. Vis. Sci. 1996, 37:886-897.
8. Bursell S.E., Clermont A.C., Oren B., King G.L. The in vivo effect of endothelins on retinal circulation in nondiabetic and diabetic rats. Invest. Ophthalmol. Vis. Sci. 1995, 36:596-607.
9. Bursell S.E., Clermont A.C., Shiba T., King G.L. Evaluating retinal circulation using video fluorescein angiography in control and diabetic rats. Curr. Eye Res. 1992, 11:287-295.
10. Campos M.M., Ongali B., De Souza Buck H., Schanstra J.P., Girolami J.P., Chabot J.G., Couture R. Expression and distribution of kinin B1 receptor in the rat brain and alterations induced by diabetes in the model of streptozotocin. Synapse 2005, 57:29-37.
11. Clermont A.C., Aiello L.P., Mori F., Aiello L.M., Bursell S.E. Vascular endothelial growth factor and severity of nonproliferative diabetic retinopathy mediate retinal hemodynamics in vivo: a potential role for vascular endothelial growth factor in the progression of nonproliferative diabetic retinopathy. Am. J. Ophthalmol. 1997, 124:433-446.
12. Clermont A.C., Brittis M., Shiba T., McGovern T., King G.L., Bursell S.E. Normalization of retinal blood flow in diabetic rats with primary intervention using insulin pumps. Invest. Ophthalmol. Vis. Sci. 1994, 35:981-990.
13. Clermont A.C., Bursell S.E. Retinal blood flow in diabetes. Microcirculation 2007, 14:49-61.
14. Couture R., Girolami J.P. Putative roles of kinin receptors in the therapeutic effects of angiotensin 1-converting enzyme inhibitors in diabetes mellitus. Eur. J. Pharmacol. 2004, 500:467-485.
15. Couture R., Harrisson M., Vianna R.M., Cloutier F. Kinin receptors in pain and inflammation. Eur. J. Pharmacol. 2001, 429:161-176.
16. Cringle S.J., Yu D.Y., Alder V.A., Su E.N. Retinal blood flow by hydrogen clearance polarography in the streptozotocin-induced diabetic rat. Invest. Ophthalmol. Vis. Sci. 1993, 34:1716-1721.
17. De Vriese A.S., Verbeuren T.J., Van de Voorde J., Lameire N.H., Vanhoutte P.M. Endothelial dysfunction in diabetes. Br. J. Pharmacol. 2000, 130:963-974.
18. Deschenes M.C., Descovich D., Moreau M., Granger L., Kuchel G.A., Mikkola T.S., Fick G.H., Chemtob S., Vaucher E., Lesk M.R. Postmenopausal hormone therapy increases retinal blood flow and protects the retinal nerve fiber layer. Invest. Ophthalmol. Vis. Sci. 2010, 51:2587-2600.
19. Dias J.P., Ismael M.A., Pilon M., de Champlain J., Ferrari B., Carayon P., Couture R. The kinin B1 receptor antagonist SSR240612 reverses tactile and cold allodynia in an experimental rat model of insulin resistance. Br. J. Pharmacol. 2007, 152:280-287.
20. Dias J.P., Talbot S., Sénécal J., Carayon P., Couture R. Kinin B1 receptor enhances the oxidative stress in a rat model of insulin resistance: outcome in hypertension, allodynia and metabolic complications. PLoS ONE 2010, 5:1-14.
21. Duckrow R.B., Beard D.C., Brennan R.W. Regional cerebral blood flow decreases during chronic and acute hyperglycemia. Stroke 1987, 18:52-58.
22. Duong T.Q., Pardue M.T., Thule P.M., Olson D.E., Cheng H., Nair G., Li Y., Kim M., Zhang X., Shen Q. Layer-specific anatomical, physiological and functional MRI of the retina. NMR Biomed. 2008, 21:978-996.
23. Edgley A.J., Tare M., Evans R.G., Skordilis C., Parkington H.C. In vivo regulation of endothelium-dependent vasodilation in the rat renal circulation and the effect of streptozotocin-induced diabetes. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2008, 295:R829-R839.
24. Feke G.T., Buzney S.M., Ogasawara H., Fujio N., Goger D.G., Spack N.P., Gabbay K.H. Retinal circulatory abnormalities in type 1 diabetes. Invest. Ophthalmol. Vis. Sci. 1994, 35:2968-2975.
25. Feng D., Bursell S.E., Clermont A.C., Lipinska I., Aiello L.P., Laffel L., King G.L., Tofler G.H. von Willebrand factor and retinal circulation in early-stage retinopathy of type 1 diabetes. Diabetes Care 2000, 23:1694-1698.
26. Frank R.N. Diabetic retinopathy. N. Engl. J. Med. 2004, 350:48-58.
27. Gabra B.H., Benrezzak O., Pheng L.H., Duta D., Daull P., Sirois P., Nantel F., Battistini B. Inhibition of type 1 diabetic hyperalgesia in streptozotocin-induced Wistar versus spontaneous gene-prone BB/Worchester rats: efficacy of a selective bradykinin B1 receptor antagonist. J. Neuropathol. Exp. Neurol. 2005, 64:782-789.
28. Gougat J., Ferrari B., Sarran L., Planchenault C., Poncelet M., Maruani J., Alonso R., Cudennec A., Croci T., Guagnini F., Urban-Szabo K., Martinolle J.P., Soubrie P., Finance O., Le Fur G. SSR240612 [(2R)-2-[((3R)-3-(1,3-benzodioxol-5-yl)-3-[[(6-methoxy-2-naphthyl)sulfonyl ]amino]propanoyl)amino]-3-(4-[[2R,6S)-2,6-dimethylpiperidinyl]methyl]pheny l)-N-isopropyl-N-methylpropanamide hydrochloride], a new nonpeptide antagonist of the bradykinin B1 receptor: biochemical and pharmacological characterization. J. Pharmacol. Exp. Ther. 2004, 309:661-669.
29. Grammas P., Riden M. Retinal endothelial cells are more susceptible to oxidative stress and increased permeability than brain-derived endothelial cells. Microvasc. Res. 2003, 65:18-23.
30. Granstam E., Granstam S.O. Involvement of nitric oxide in the regulation of regional hemodynamics in streptozotocin-diabetic rats. Physiol. Res. 2003, 52:159-169.
31. Greenberg J.H., Sohn N.W., Hand P.J. Nitric oxide and the cerebral-blood-flow response to somatosensory activation following deafferentation. Exp. Brain Res. 1999, 129:541-550.
32. Grunwald J.E., DuPont J., Riva C.E. Retinal haemodynamics in patients with early diabetes mellitus. Br. J. Ophthalmol. 1996, 80:327-331.
33. Harik S.I., LaManna J.C. Vascular perfusion and blood-brain glucose transport in acute and chronic hyperglycemia. J. Neurochem. 1988, 51:1924-1929.
34. Higashi S., Clermont A.C., Dhir V., Bursell S.E. Reversibility of retinal flow abnormalities is disease-duration dependent in diabetic rats. Diabetes 1998, 47:653-659.
35. Horio N., Clermont A.C., Abiko A., Abiko T., Shoelson B.D., Bursell S.E., Feener E.P. Angiotensin AT(1) receptor antagonism normalizes retinal blood flow and acetylcholine-induced vasodilatation in normotensive diabetic rats. Diabetologia 2004, 47:113-123.
36. Kawagishi T., Nishizawa Y., Emoto M., Konishi T., Maekawa K., Hagiwara S., Okuno Y., Inada H., Isshiki G., Morii H. Impaired retinal artery blood flow in IDDM patients before clinical manifestations of diabetic retinopathy. Diabetes Care 1995, 18:1544-1549.
37. Knudsen G.M., Gobel U., Paulson O.B., Kuschinsky W. Regional density of perfused capillaries and cerebral blood flow in untreated short-term and long-term streptozotocin diabetes. J. Cereb. Blood Flow Metab. 1991, 11:361-365.
38. Kuznetsova T.P., Chesnokova N.B., Paskhina T.S. Activity of tissue and plasma kallikrein and level of their precursors in eye tissue structures and media of healthy rabbits. Vopr. Med. Khim. 1991, 37:79-82.
39. Lawson S.R., Gabra B.H., Nantel F., Battistini B., Sirois P. Effects of a selective bradykinin B1 receptor antagonist on increased plasma extravasation in streptozotocin-induced diabetic rats: distinct vasculopathic profile of major key organs. Eur. J. Pharmacol. 2005, 514:69-78.
40. Lear J.L., Ackermann R.F., Kameyama M., Kuhl D.E. Evaluation of [123I]isopropyliodoamphetamine as a tracer for local cerebral blood flow using direct autoradiographic comparison. J. Cereb. Blood Flow Metab. 1982, 2:179-185.
41. Leeb-Lundberg L.M., Marceau F., Muller-Esterl W., Pettibone D.J., Zuraw B.L. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol. Rev. 2005, 57:27-77.
42. Lim S.K., Park M.J., Jung H.K., Park A.Y., Kim D.I., Kim J.C., Bae C.S., Kim K.Y., Yoon K.C., Han H.J., Park S.H. Bradykinin stimulates glutamate uptake via both B1R and B2R activation in a human retinal pigment epithelial cells. Life Sci. 2008, 83:761-770.
43. Lin J.C., Talbot S., Lahjouji K., Roy J.P., Senecal J., Couture R., Morin A. Mechanism of cigarette smoke-induced kinin B(1) receptor expression in rat airways. Peptides 2010, 31:1940-1945.
44. Ma J.X., Song Q., Hatcher H.C., Crouch R.K., Chao L., Chao J. Expression and cellular localization of the kallikrein-kinin system in human ocular tissues. Exp. Eye Res. 1996, 63:19-26.
45. Manschot S.M., Biessels G.J., Cameron N.E., Cotter M.A., Kamal A., Kappelle L.J., Gispen W.H. Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in streptozotocin-diabetic rats. Brain Res. 2003, 966:274-282.
46. Marceau F. Kinin B1 receptors: a review. Immunopharmacology 1995, 30:1-26.
47. Marceau F., Hess J.F., Bachvarov D.R. The B1 receptors for kinins. Pharmacol. Rev. 1998, 50:357-386.
48. Marceau F., Larrivee J.F., Saint-Jacques E., Bachvarov D.R. The kinin B1 receptor: an inducible G protein coupled receptor. Can. J. Physiol. Pharmacol. 1997, 75:725-730.
49. McLean P.G., Perretti M., Ahluwalia A. Inducible expression of the kinin B1 receptor in the endotoxemic heart: mechanisms of des-Arg9bradykinin-induced coronary vasodilation. Br. J. Pharmacol. 1999, 128:275-282.
50. Oyama Y., Kawasaki H., Hattori Y., Kanno M. Attenuation of endothelium-dependent relaxation in aorta from diabetic rats. Eur. J. Pharmacol. 1986, 132:75-78.
51. Pemp B., Polska E., Garhofer G., Bayerle-Eder M., Kautzky-Willer A., Schmetterer L. Retinal blood flow in type 1 diabetic patients with no or mild diabetic retinopathy during euglycemic clamp. Diabetes Care 2010, 33:2038-2042.
52. Phipps J.A., Feener E.P. The kallikrein-kinin system in diabetic retinopathy: lessons for the kidney. Kidney Int. 2008, 73:1114-1119.
53. Pouliot M., Deschenes M.C., Hetu S., Chemtob S., Lesk M.R., Couture R., Vaucher E. Quantitative and regional measurement of retinal blood flow in rats using N-isopropyl-p-[14C]-iodoamphetamine ([14C]-IMP). Exp. Eye Res. 2009, 89:960-966.
54. Pugliese G., Tilton R.G., Speedy A., Santarelli E., Eades D.M., Province M.A., Kilo C., Sherman W.R., Williamson J.R. Modulation of hemodynamic and vascular filtration changes in diabetic rats by dietary myo-inositol. Diabetes 1990, 39:312-322.
55. Regoli D., Barabe J. Pharmacology of bradykinin and related kinins. Pharmacol. Rev. 1980, 32:1-46.
56. Regoli D., Nsa Allogho S., Rizzi A., Gobeil F.J. Bradykinin receptors and their antagonists. Eur. J. Pharmacol. 1998, 348:1-10.
57. Rodi D., Couture R., Ongali B., Simonato M. Targeting kinin receptors for the treatment of neurological diseases. Curr. Pharm. Des. 2005, 11:1313-1326.
58. Schmetterer L., Findl O., Fasching P., Ferber W., Strenn K., Breiteneder H., Adam H., Eichler H.G., Wolzt M. Nitric oxide and ocular blood flow in patients with IDDM. Diabetes 1997, 46:653-658.
59. Sutera S.P., Chang K., Marvel J., Williamson J.R. Concurrent increases in regional hematocrit and blood flow in diabetic rats: prevention by sorbinil. Am. J. Physiol. 1992, 263:H945-H950.
60. Tabit C.E., Chung W.B., Hamburg N.M., Vita J.A. Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications. Rev. Endocr. Metab. Disord. 2010, 11:61-74.
61. Takagi C., Bursell S.E., Lin Y.W., Takagi H., Duh E., Jiang Z., Clermont A.C., King G.L. Regulation of retinal hemodynamics in diabetic rats by increased expression and action of endothelin-1. Invest. Ophthalmol. Vis. Sci. 1996, 37:2504-2518.
62. Takeda H., Kimura Y., Higashida H., Yokoyama S. Localization of B2 bradykinin receptor mRNA in the rat retina and sclerocornea. Immunopharmacology 1999, 45:51-55.
63. Taylor P.D., McCarthy A.L., Thomas C.R., Poston L. Endothelium-dependent relaxation and noradrenaline sensitivity in mesenteric resistance arteries of streptozotocin-induced diabetic rats. Br. J. Pharmacol. 1992, 107:393-399.
64. Tilton R.G., Chang K., Pugliese G., Eades D.M., Province M.A., Sherman W.R., Kilo C., Williamson J.R. Prevention of hemodynamic and vascular albumin filtration changes in diabetic rats by aldose reductase inhibitors. Diabetes 1989, 38:1258-1270.
65. Vaucher E., Borredon J., Bonvento G., Seylaz J., Lacombe P. Autoradiographic evidence for flow-metabolism uncoupling during stimulation of the nucleus basalis of Meynert in the conscious rat. J. Cereb. Blood Flow Metab. 1997, 17:686-694.
66. Westermann D., Walther T., Savvatis K., Escher F., Sobirey M., Riad A., Bader M., Schultheiss H.P., Tschope C. Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental diabetic cardiomyopathy. Diabetes 2009, 58:1373-1381.
67. Wilkinson-Berka J.L., Fletcher E.L. Angiotensin and bradykinin: targets for the treatment of vascular and neuro-glial pathology in diabetic retinopathy. Curr. Pharm. Des. 2004, 10:3313-3330.