Nitric oxide and the cerebral-blood-flow response to somatosensory activation following deafferentation

Experimental Brain Research

Volumn 129, Issue 4, 1999, Pages 541-550

  Greenberg, Joel H ^a   Sohn, Nak Won ^a,b   Hand, Peter J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Kyung Hee University   (South Korea)

Author keywords

Flow activation couple; Nitric oxide; Plasticity; Vibrissae

Indexed keywords

ARGININE; CARBON 14; IOFETAMINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; BRAIN BLOOD FLOW; BRAIN CORTEX; BRAIN METABOLISM; CONTROLLED STUDY; DEAFFERENTATION; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SOMATOSENSORY SYSTEM;

EID: 0032761223     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002210050924     Document Type: Article

References (72)

1. Adachi K, Takahashi S, Melzer P, Campos KL, Nelson T, Kennedy C, Sokoloff L (1994) Increases in local cerebral blood flow associated with somatosensory activation are not mediated by NO. Am J Physiol 267:H2155-H2162
2. Adachi T, Inanami O, Sato A (1992) Nitric oxide (NO) is involved in increased cerebral cortical blood flow following stimulation of the nucleus basalis of Meynert in anesthetized rats. Neurosci Lett 139:201-204
3. Arnal JF, Warin L, Michel JB (1992) Determinants of aortic cyclic guanosine monophosphate in hypertension induced by chronic inhibition of nitric oxide synthase. J Clin Invest 90:647-652
4. Ayata C, Ma J, Meng W, Huang P, Moskowitz MA (1996) L-NA-sensitive rCBF augmentation during vibrissal stimulation in type III nitric oxide synthase mutant mice. J Cereb Blood Flow Metab 16:539-541
5. Beckman JS, Koppenol WH (1996) Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 271: C1424-C1437
6. Bredt DS, Snyder SH (1990) Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc Natl Acad Sci USA 87: 682-685
7. Brian JJ, Faraci FM, Heistad DD (1996) Recent insights into the regulation of cerebral circulation. Clin Exp Pharmacol Physiol 23:449-457
8. Cholet N, Bonvento G, Seylaz J (1996) Effect of neuronal NO synthase inhibition on the cerebral vasodilatory response to somatosensory stimulation. Brain Res 708:197-200
9. Cholet N, Seylaz J, Lacombe P, Bonvento G (1997) Local uncoupling of the cerebrovascular and metabolic responses to somatosensory stimulation after neuronal nitric oxide synthase inhibition. J Cereb Blood Flow Metab 17:1191-1201
10. Dietrich WD, Ginsberg MD, Busto R, Smith DW (1985) Metabolic alterations in rat somatosensory cortex following unilateral vibrissal removal. J Neurosci 5:874-880
11. Dirnagl U, Kaplan B, Jacewicz M, Pulsinelli W (1989) Continuous measurement of cerebral cortical blood flow by laser-Doppler flowmetry in a rat stroke model. J Cereb Blood Flow Metab 9:589-596
12. Dirnagl U, Lindauer U, Villringer A (1993) Role of nitric oxide in the coupling of cerebral blood flow to neuronal activation in rats. Neurosci Lett 149:43-46
13. Dirnagl U, Niwa K, Lindauer U, Villringer A (1994) Coupling of cerebral blood flow to neuronal activation: role of adenosine and nitric oxide. Am J Physiol 267:H296-H301
14. Edvinsson L (1987) Innervation of the cerebral circulation. Ann NY Acad Sci 519:334-348
15. Eyre JA, Essex TJ, Flecknell PA, Bartholomew PH, Sinclair JI (1988) A comparison of measurements of cerebral blood flow in the rabbit using laser Doppler spectroscopy and radionuclide labelled microspheres. Clin Phys Physiol Meas 9: 65-74
16. Faraci FM, Brian JJ (1994) Nitric oxide and the cerebral circulation. Stroke 25:692-703
17. Ginsberg MD, Dietrich WD, Busto R (1987) Coupled forebrain increases of local cerebral glucose utilization and blood flow during physiologic stimulation of a somatosensory pathway in the rat: demonstration by double-label autoradiography. Neurology 37:11-19
18. Goadsby PJ, Kaube H, Hoskin KL (1992) Nitric oxide synthesis couples cerebral blood flow and metabolism. Brain Res 595: 167-170
19. Gobel U, Theilen H, Kuschinsky W (1990) Congruence of total and perfused capillary network in rat brains. Circ Res 66: 271-281
20. Greenberg JH, Hand PJ, Sylvestro A, Reivich M (1979) Localized metabolic-flow couple during functional activity. Acta Neurol Scand 60[Suppl 72]:12-13
21. Greenberg JH, LoBrotto C, Lombard KM, Chen J (1999) Postmortem diffusion of autoradiographic blood flow tracers. Brain Res (in press)
22. Grinvald A, Lieke E, Frostig RD, Gilbert CD, Wiesel TN (1986) Functional architecture of cortex revealed by optical imaging of intrinsic signals. Nature 324:361-364
23. Hand PJ (1981) Deoxyglucose Method. In: Heimer L, Robards MJ (eds) Methods in contemporary neuroanatomy: the tracing of central nervous pathways. Plenum Press, New York, pp 511-538
24. Iadecola C, Pelligrino DA, Moskowitz MA, Lassen NA (1994) Nitric oxide synthase inhibition and cerebrovascular regulation. J Cereb Blood Flow Metab 14:175-192
25. Irikura K, Maynard KI, Moskowitz MA (1994) Importance of nitric oxide synthase inhibition to the attenuated vascular responses induced by topical L-nitroarginine during vibrissal stimulation. J Cereb Blood Flow Metab 14:45-48
26. Jay TM, Lucignani G, Crane AM, Jehle J, Sokoloff L (1988) Measurement of local cerebral blood flow with [14 C]iodoantipyrine in the mouse. J Cereb Blood Flow Metab 8:121-129
27. Kossut M, Hand P (1984) Early development of changes in cortical representation of C3 vibrissa following neonatal denervation of surrounding vibrissa receptors: a 2-deoxyglucose study in the rat. Neurosci Lett 46:7-12
28. Kossut M, Hand PJ, Greenberg J, Hand CL (1988) Single vibrissal cortical column in SI cortex of rat and its alterations in neonatal and adult vibrissa-deafferented animals: a quantitative 2DG study. J Neurophysiol 60:829-852
29. Kuhl DE, Barrio JR, Huang SC, Selin C, Ackermann RF, Lear JL, Wu JL, Lin TH, Phelps ME (1982) Quantifying local cerebral blood flow by N-isopropyl-p-[123I]iodoamphetamine (IMP) tomography. J Nucl Med 23:196-203
30. Kuschinsky W (1991) Coupling of function, metabolism, and blood flow in the brain. Neurosurg Rev 14:163-168
31. Kuschinsky W, Wahl M, Bosse O, Thurau K (1972) Perivascular potassium and pH as determinants of local pial arterial diameter in cats. A microapplication study. Circ Res 31:240-247
32. Lear JL, Ackermann RF, Kameyama M, Kuhl DE (1982) Evaluation of [123I]isopropyliodoamphetamine as a tracer for local cerebral blood flow using direct autoradiographic comparison. J Cereb Blood Flow Metab 2:179-185
33. Lindauer U, Villringer A, Dirnagl U (1993) Characterization of CBF response to somatosensory stimulation: model and influence of anesthetics. Am J Physiol 264:H1223-H1228
34. Lindauer U, Megow D, Schultze J, Weber JR, Dirnagl U (1996) Nitric oxide synthase inhibition does not affect somatosensory evoked potentials in the rat. Neurosci Lett 216:207-210
35. Lipton SA, Choi YB, Pan ZH, Lei SZ, Chen HS, Sucher NJ, Loscalzo J, Singel DJ, Stamler JS (1993) A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 364: 626-632
36. Lou HC, Edvinsson L, MacKenzie ET (1987) The concept of coupling blood flow to brain function: revision required? Ann Neurol 22:289-297
37. Ma J, Ayata C, Huang PL, Fishman MC, Moskowitz MA (1996) Regional cerebral blood flow response to vibrissal stimulation in mice lacking type I NOS gene expression. Am J Physiol 270: H1085-H1090
38. Masino SA, Kwon MC, Dory Y, Frostig RD (1993) Characterization of functional organization within rat barrel cortex using intrinsic signal optical imaging through a thinned skull. Proc Natl Acad Sci USA 90:9998-10002
39. Moncada S (1997) Nitric oxide in the vasculature: physiology and pathophysiology. Ann NY Acad Sci 811:60-67
40. Moore PK, Wallace P, Gaffen Z, Hart SL, Babbedge RC (1993) Characterization of the novel nitric oxide synthase inhibitor 7-nitro indazole and related indazoles: antinociceptive and cardiovascular effects. Br J Pharmacol 110:219-224
41. Muldoon SM, Hart JL, Bowen KA, Freas W (1988) Attenuation of endothelium-mediated vasodilation by halothane. Anesthesiology 68:31-37
42. Narayan SM, Santori EM, Toga AW (1994) Mapping functional activity in rodent cortex using optical intrinsic signals. Cereb Cortex 4:195-204
43. Northington FJ, Matherne GP, Berne RM (1992) Competitive inhibition of nitric oxide synthase prevents the cortical hyperemia associated with peripheral nerve stimulation. Proc Natl Acad Sci USA 89:6649-6652
44. Reif DW, McCreedy SA (1995) N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a different pattern of inactivation toward the three nitric oxide synthases. Arch Biochem Biophys 320:170-176
45. Ringel M, Bryan RM, Vannucci RC (1991) Regional cerebral blood flow during hypoxia-ischemia in the immature rat: comparison of iodoantipyrine and iodoamphetamine as radioactive tracers. Brain Res Dev Brain Res 59:231-235
46. Roy CW, Sherrington CS (1890) On the regulation of the blood supply of the brain. J Physiol 11:85-108
47. Sakurada O, Kennedy C, Jehle J, Brown JD, Carbin GL, Sokoloff L (1978) Measurement of local cerebral blood flow with iodo [14 C] antipyrine. Am J Physiol 234:H59-H66
48. Savaki HE, Davidsen L, Smith C, Sokoloff L (1980) Measurement of free glucose turnover in brain. J Neurochem 35:495-502
49. Shapiro HM, Drummond JC (1994) Cerebral Physiology. In: Miller RD (ed) Anesthesia. Churchill Livingstone, New York, pp 689-730
50. Sigmon DH, Florentino-Pineda I, Van DA, Beierwaltes WH (1995) Halothane impairs the hemodynamic influence of endothelium-derived nitric oxide. Anesthesiology 82:135-143
51. Simons DJ, Carvell GE, Hershey AE, Bryant DP (1992) Responses of barrel cortex neurons in awake rats and effects of urethane anesthesia. Exp Brain Res 91:259-272
52. Skinhoj E (1966) Regulation of cerebral blood flow as a single function of the interstitial pH in the brain. A hypothesis. Acta Neurol Scand 42:604-607
53. Smith AL, Wollman H (1972) Cerebral blood flow and metabolism: effects of anesthetic drugs and techniques. Anesthesiology 36:378-400
54. Sohn NW, Hand PJ, Greenberg JH (1996) Effect of nitric oxide inhibition on plasticity in the rat first somatosensory (S1) cortex. Neurosci Abst 22:303.2
55. Sokoloff L (1981) Relationships among local functional activity, energy metabolism, and blood flow in the central nervous system. Fed Proc 40:2311-2316
56. Sokoloff L, Reivich M, Kennedy C, Des Rosiers MH, Patlak CS, Pettigrew KD, Sakurada O, Shinohara M (1977) The [14 C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 28:97-916
57. Tanaka K (1996) Is nitric oxide really important for regulation of the cerebral circulation? Yes or no? Keio J Med 45:14-27
58. Todd MM, Weeks J (1996) Comparative effects of propofol, pentobarbital, and isoflurane on cerebral blood flow and blood volume. J Neurosurg Anesthesiol 8:296-303
59. Todd MM, Wu B, Warner DS, Maktabi M (1994) The dose-related effects of nitric oxide synthase inhibition on cerebral blood flow during isoflurane and pentobarbital anesthesia. Anesthesiology 80:1128-1136
60. Traystman RJ, Moore LE, Helfaer MA, Davis S, Banasiak K, Williams M, Hurn PD (1995) Nitro-L-arginine analogues. Dose-and time-related nitric oxide synthase inhibition in brain. Stroke 26:864-869
61. Ueki M, Mies G, Hossmann KA (1992) Effect of alpha-chloralose, halothane, pentobarbital and nitrous oxide anesthesia on metabolic coupling in somatosensory cortex of rat. Acta Anaesthesiol Scand 36:318-322
62. Van der Loos H, Woolsey TA (1973) Somatosensory cortex: structural alterations following early injury to sense organs. Science 179:395-398
63. + at pial arteries of cats. Acta Neurol Scand Suppl 64:218-219
64. Wang Q, Kjaer T, Jorgensen MB, Paulson OB, Lassen NA, Diemer NH, Lou HC (1993) Nitric oxide does not act as a mediator coupling cerebral blood flow to neural activity following somatosensory stimuli in rats. Neurol Res 15:33-36
65. Welker C (1976) Receptive fields of barrels in the somatosensory neocortex of the rat. J Comp Neurol 166:173-189
66. Weller WL, Johnson JI (1975) Barrels in cerebral cortex altered by receptor disruption in newborn, but not in five-day-old mice (Cricetidae and Muridae). Brain Res 83:504-508
67. Williams JL, Shea M, Furlan AJ, Little JR, Jones SC (1991) Importance of freezing time when iodoantipyrine is used for measurement of cerebral blood flow. Am J Physiol 261:H252-H256
68. Wong-Riley M (1979) Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry. Brain Res 171:11-28
69. Woolsey TA, Van der Loos H (1970) The structural organization of layer IV in the somatosensory region (SI) of mouse cerebral cortex. The description of a cortical field composed of discrete cytoarchitectonic units. Brain Res 17:205-242
70. Woolsey TA, Welker C, Schwartz RH (1975) Comparative anatomical studies of the SmL face cortex with special reference to the occurrence of "barrels" in layer IV. J Comp Neurol 164:79-94
71. Woolsey TA, Rovainen CM, Cox SB, Henegar MH, Liang GE, Liu D, Moskalenko YE, Sui J, Wei L (1996) Neuronal units linked to microvascular modules in cerebral cortex: response elements for imaging the brain. Cereb Cortex 6:647-660
72. Yoshida T, Limmroth V, Irikura K, Moskowitz MA (1994) The NOS inhibitor, 7-nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels. J Cereb Blood Flow Metab 14:924-929