Surfactant protein A (SP-A): The alveolus beyond

FASEB Journal

Volumn 15, Issue 1, 2001, Pages 59-69

  Khubchandani, K R ^a   Snyder, J M ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Cystic fibrosis; Extra alveolar sites; Innate immunity; Lectins

Indexed keywords

LECTIN; LIPOPOLYSACCHARIDE; OPSONIN; PLASMA PROTEIN; SURFACTANT PROTEIN A;

BACTERIAL INFECTION; CYSTIC FIBROSIS; GASTROINTESTINAL TRACT; IMMUNITY; LUNG ALVEOLUS; LUNG ALVEOLUS CELL TYPE 2; LUNG INJURY; MACROPHAGE ACTIVATION; MESOTHELIUM; MIDDLE EAR; MOUSE; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROSTATE; PROTEIN SECRETION; RESPIRATORY SYSTEM; REVIEW; SPLEEN; SYNOVIUM;

ANIMALS; BLOOD PROTEINS; DIGESTIVE SYSTEM; EAR, MIDDLE; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MALE; OPSONIN PROTEINS; PROSTATE; PROTEOLIPIDS; PULMONARY ALVEOLI; PULMONARY SURFACTANT-ASSOCIATED PROTEIN A; PULMONARY SURFACTANT-ASSOCIATED PROTEINS; PULMONARY SURFACTANTS; RECEPTORS, CELL SURFACE; SPLEEN; SURFACE TENSION; SYNOVIAL MEMBRANE; THYMUS GLAND;

BACTERIA (MICROORGANISMS);

EID: 0035175493     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.00-0318rev     Document Type: Review

References (118)

1. The pulmonary surfactant system: Biochemical and clinical aspects
2. Function and regulation of expression of pulmonary surfactant-associated proteins
3. CP 4: A pneumocyte-derived collagenous surfactant-associated protein. Evidence of heterogeneity of collagenous surfactant proteins
4. Collectins and pulmonary host defense
5. Isolation and characterization of the human pulmonary surfactant apoprorein gene
6. Characterization of a second human pulmonary surfactant-associated protein SP-A gene
7. Isolation and characterization of cDNA clones for the 35-kDa pulmonary surfactant-associated protein
8. Structural comparison of recombinant pulmonary surfactant protein SP-A derived from two human coding sequences: Implications for the chain composition of natural human SP-A
9. The major lung surfactant protein. SP 28-36, is a calcium-dependent, carbohydrate-binding protein
10. Association of low levels of mannan-binding protein with a common defect of opsonization
11. Association of pulmonary surfactant protein A (SP-A) gene and respiratory distress syndrome: Interaction with SP-B
12. Surfactant protein A-deficient mice are susceptible to group B streptococcal infection
13. Surfactant protein-A-deficient mice are susceptible to Pseudomonas aeruginosa infection
14. Surfactant protein-A enhances respiratory syncytial virus clearance in vivo
15. Surfactant protein A mediates mycoplasmacidal activity of alveolar macrophages by production of peroxynitrite
16. SP-A enhances viral clearance and inhibits inflammation after pulmonary adenoviral infection
17. A novel procedure for the rapid isolation of surfactant protein A with retention of its alveolar-macrophage-stimulating properties
18. Effects of surfactant protein A and surfactant lipids on lymphocyte proliferation in vitro
19. Surfactant protein A stimulation of inflammatory cytokine and immunoglobulin production
20. Effect of SP-A and surfactant lipids on expression of cell surface markers in the THP-1 monocytic cell line
21. cDNA cloning and primary structure analysis of C1qR(P), the human C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro
22. Purification of a cell-surface receptor for surfactant protein A
23. SP-A enhances uptake of bacillus Calmette-Guerin by macrophages through a specific SP-A receptor
24. Developmental regulation of phospholipid secretion by fetal type II pneumocytes
25. Regulation of pulmonary surfactant apoprotein SP 28-36 gene in fetal human lung
26. Appearance of apoproteins of pulmonary surfactant in human amniotic fluid
27. Developmental expression of SP-A and SP-A mRNA in the proximal and distal respiratory epithelium in the human fetus and newborn
28. Regulation of the synthesis of the major surfactant apoprotein in fetal rabbit lung tissue
29. Induction of surfactant protein in fetal lung. Effects of cAMP and dexamethasone on SAP-35 RNA and synthesis
30. Differential effects of epidermal growth factor and transforming growth factor-β on synthesis of Mr = 35,000 surfactant-associated protein in fetal lung
31. Interferon-gamma and synthesis of surfactant components by cultured human fetal lung
32. Prostaglandins regulate surfactant protein A (SP-A) gene expression in human fetal lung in vitro
33. Oxygen modulates the differentiation of human fetal lung in vitro and its responsiveness to cAMP
34. Differential accumulation of surfactant protein A, B, and C mRNAs in two epithelial ceil types of hyperoxic lung
35. Surfactant protein A protects growing cells and reduces TNF-alpha activity from LPS-stimulated macrophages
36. Overexpression of surfactant protein SP-A, SP-B, and SP-C mRNA in rat lungs with lipopolysaccharide-induced injury
37. Adenosine 3′,5′-monophosphate analogs and beta-adrenergic agonists induce the synthesis of the major surfactant apoprotein in human fetal lung in vitro
38. Insulin inhibits the accumulation of the major lung surfactant apoprotein in human fetal lung explants maintained in vitro
39. Tumor necrosis factor-alpha inhibits expression of pulmonary surfactant protein
40. Phorbol ester inhibits surfactant protein SP-A and SP-B expression
41. Differential effects of glucocorticoid on expression of surfactant proteins in a human lung adenocarcinoma cell line
42. Differential regulation of SP-A1 and SP-A2 genes by cAMP, glucocorticoids, and insulin
43. Effects of surfactant apolipoproteins on liposome structure: Implications for tubular myelin formation
44. Expression of the 35 kDa and low molecular weight surfactant-associated proteins in the lungs of infants dying with respiratory distress syndrome
45. Altered surfactant function and structure in SP-A gene targeted mice
46. Surfactant apoprotein Mr = 26,000-36,000 enhances uptake of liposomes by type II cells
47. Pulmonary surfactant protein A (SP-A) specifically binds dipalmitoylphosphatidylcholine
48. Degradation of surfactant lipids and surfactant protein A by alveolar macrophages in vitro
49. Surfactant-associated protein inhibits phospholipid secretion from type II cells
50. A protein that inhibits surfactant in respiratory distress syndrome
51. A biophysical mechanism by which plasma proteins inhibit lung surfactant activity
52. Pulmonary surfactant-associated protein A enhances the surface activity of lipid extract surfactant and reverses inhibition by blood proteins in vitro
53. Characteristics of surfactant from SP-A-deficient mice
54. Binding of surfactant protein A to the lipid A moiety of bacterial lipopolysaccharides
55. Secretion of cytokines by rat alveolar epithelial cells: Possible regulatory role for SP-A
56. Potential role of surfactant proteins A and D in innate lung defense against pathogens
57. Opsonic activities of surfactant proteins A and D in phagocytosis of gram-negative bacteria by alveolar macrophages
58. Pulmonary surfactant protein A enhances the host-defense mechanism of rat alveolar macrophages
59. Immunomodulatory functions of surfactant
60. Human pulmonary surfactant protein (SP-A), a protein structurally homologous to C1q, can enhance FcR- and CR1- mediated phagocytosis
61. Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis by a direct interaction with human macrophages
62. Interaction of lung surfactant protein A with alveolar macrophages
63. Surfactant protein A regulates cytokine production in the monocytic cell line THP-1
64. Nitric oxide production by rat alveolar macrophages can be modulated in vitro by surfactant protein A
65. Lung surfactant protein A (SP-A) activates a phosphoinositide/calcium signaling pathway in alveolar macrophages
66. Pulmonary surfactant proteins A and D enhance neutrophil uptake of bacteria
67. Cystic fibrosis: Pathogenesis, pulmonary infection, and treatment
68. Surfactant proteins A and D increase in response to intratracheal lipopolysaccharide
69. Deficient hydrophilic lung surfactant proteins A and D with normal surfactant phospholipid molecular species in cystic fibrosis
70. Surfactant protein A stimulates phagocytosis of specific pulmonary pathogens by alveolar macrophages
71. Human lung surfactant protein A exists in several different oligomeric states: Oligomer size distribution varies between patient groups
72. Lung surfactant proteins A and D can inhibit specific IgE binding to the allergens of Aspergillus fumigatus and block allergen-induced histamine release from human basophils
73. Surfactant protein-A reduces binding and phagocytosis of Pneumocystis carinii by human alveolar macrophages in vitro
74. Binding of host collectins to the pathogenic yeast Cryptococcus neoformans: Human surfactant protein D acts as an agglutinin for acapsular yeast cells
75. Lung surfactant protein A (SP-A) enhances serum-independent phagocytosis of bacteria by alveolar macrophages
76. SP-A enhances phagocytosis of Klebsiella by interaction with capsular polysaccharides and alveolar macrophages
77. Surfactant protein A, but not surfactant protein D, is an opsonin for influenza A virus phagocytosis by rat alveolar macrophages
78. Binding of surfactant protein A (SP-A) to herpes simplex virus type 1-infected cells is mediated by the carbohydrate moiety of SP-A
79. Interactions of surfactant protein A with influenza A viruses: Binding and neutralization
80. Deficient lung surfactant apoproteins in amniotic fluid with mature phospholipid profile from diabetic pregnancies
81. The concentrations of the 35-kDa surfactant apoprotein in amniotic fluid from normal and diabetic pregnancies
82. Surfactant proteins in the diagnosis of fetal lung maturity. I. Predictive accuracy of the 35 kD protein, the lecithin/sphingomyelin ratio, and phosphatidylglycerol
83. Functional abnormalities of lung surfactant in experimental acute alveolar injury in the dog
84. Surfactant proteins A and D: Disease markers
85. Surfactant composition in infants and young children with cystic fibrosis
86. Decreased surfactant protein A in patients with bacterial pneumonia
87. Surfactant content in children with inflammatory lung disease
88. Surfactant proteins A and D in premature baboons with chronic lung injury (Bronchopulmonary dysplasia). Evidence for an inhibition of secretion
89. Increased recovery of surfactant protein A in AIDS-related pneumonia
90. Idiopathic pulmonary fibrosis. Abnormalities in the bronchoalveolar lavage content of surfactant protein A
91. Elevated surfactant protein A in bronchoalveolar lavage fluids from sarcoidosis and hypersensitivity pneumonitis patients
92. Surfactant protein-A concentration in bronchoalveolar lavage fluids of patients with pulmonary alveolar proteinosis
93. Serum surfactant protein-A levels in patients with acute cardiogenic pulmonary edema and adult respiratory distress syndrome
94. Elevated levels of lung surfactant protein A in sera from patients with idiopathic pulmonary fibrosis and pulmonary alveolar proteinosis
95. Conductive airway surfactant: Surface tension function, biochemical composition, and possible alveolar origin
96. An immunohistochemical study of bronchial cells producing surfactant protein A in the developing human fetal lung
97. SP-A2 gene expression in human fetal lung airways
98. SP-A2 in adult human conducting airways
99. Surfactant protein A2 gene expression by human airway submucosal gland cells
100. Surface-active agent in Eustachian tube function
101. Effect of exogenous surfactant on Eustachian tube function in the rat
102. Presence of an 80 kilodalton protein, cross-reacted with monoclonal antibodies to pulmonary surfactant protein A, in the human middle ear
103. Implication of surfactant apoprotein in otitis media with effusion
104. Surfactant protein A in rabbit sinus and middle ear mucosa
105. Surfactant protein A and D expression in the porcine Eustachian tube
106. Analysis of Eustachian surfactant and its function as a release agent
107. Gastric mucosal barrier: Hydrophobic lining to the lumen of the stomach
108. A mucosal barrier of gastric surfactant identified in the human stomach
109. Pulmonary surfactant protein A (SP-A) is expressed by epithelial cells of small and large intestine
110. Collectins: Collectors of microorganisms for the innate immune system
111. Isolation and characterization of surfactant-like particles in rat and human colon
112. Seminal plasmin, an antimicrobial protein from bovine seminal plasma, inhibits peptidoglycan synthesis in Escherichia coli
113. Analysis of genomic regions involved in regulation of the rabbit surfactant protein A gene in transgenic mice
114. Surfactant protein A and lamellar bodies: A homologous secretory function of peritoneum, synovium, and lung
115. Deficiency of lubricating surfactant lining the articular surfaces of replaced hips and knees
116. Surfactant barrier lining peritoneal mesothelium: Lubricant and release agent
117. Pulmonary surfactant protein A binds to Cryptococcus neoformans without promoting phagocytosis
118. Surfactant protein A enhances alveolar macrophage phagocytosis of a live, mucoid strain of P. aeruginosa