Lack of the receptor for advanced glycation end-products attenuates e. coli pneumonia in mice

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Ramsgaard, Lasse ^a,d   Englert, Judson M ^a   Manni, Michelle L ^a   Milutinovic, Pavle S ^a   Gefter, Julia ^a   Tobolewski, Jacob ^a   Crum, Lauren ^a   Coudriet, Gina M ^a   Piganelli, Jon ^b   Zamora, Ruben ^c   Vodovotz, Yoram ^c   Enghild, Jan J ^d   Oury, Tim D ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^c MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE   (United States)

^d AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; BACTERIUM LIPOPOLYSACCHARIDE; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 12; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR ALPHA; ADVANCED GLYCOSYLATION END PRODUCT RECEPTOR; ADVANCED GLYCOSYLATION END-PRODUCT RECEPTOR; IMMUNOGLOBULIN RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PEROXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENZYME ACTIVITY; ESCHERICHIA COLI PNEUMONIA; KNOCKOUT MOUSE; LOBAR PNEUMONIA; LUNG HOMOGENATE; LUNG LAVAGE; MALE; MICROBIAL ATTENUATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMISTRY; ESCHERICHIA COLI; GENETICS; IN VITRO STUDY; LUNG; METABOLISM; MICROBIOLOGY; MOUSE MUTANT; PATHOGENICITY; PNEUMONIA; WESTERN BLOTTING;

BACTERIA (MICROORGANISMS); MUS;

ANIMALS; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; CHEMOKINE CCL2; CHEMOKINE CCL3; ESCHERICHIA COLI; INTERLEUKIN-12; INTERLEUKIN-1BETA; INTERLEUKIN-6; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PEROXIDASE; PNEUMONIA; RECEPTORS, IMMUNOLOGIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79956353794     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020132     Document Type: Article

References (49)

1. Ware LB, Matthay MA, (2000) The acute respiratory distress syndrome. N Engl J Med 342: 1334-1349.
2. Schmidt AM, Vianna M, Gerlach M, Brett J, Ryan J, et al. (1992) Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface. J Biol Chem 267: 14987-14997.
3. Pachydaki SI, Tari SR, Lee SE, Ma W, Tseng JJ, et al. (2006) Upregulation of RAGE and its ligands in proliferative retinal disease. Exp Eye Res 82: 807-815.
4. Cipollone F, Iezzi A, Fazia M, Zucchelli M, Pini B, et al. (2003) The receptor RAGE as a progression factor amplifying arachidonate-dependent inflammatory and proteolytic response in human atherosclerotic plaques: role of glycemic control. Circulation 108: 1070-1077.
5. Englert JM, Hanford LE, Kaminski N, Tobolewski JM, Tan RJ, et al. (2008) A role for the receptor for advanced glycation end products in idiopathic pulmonary fibrosis. Am J Pathol 172: 583-591.
6. Queisser MA, Kouri FM, Konigshoff M, Wygrecka M, Schubert U, et al. (2008) Loss of RAGE in pulmonary fibrosis: molecular relations to functional changes in pulmonary cell types. Am J Respir Cell Mol Biol 39: 337-345.
7. Hanford LE, Fattman CL, Shaefer LM, Enghild JJ, Valnickova Z, et al. (2003) Regulation of receptor for advanced glycation end products during bleomycin-induced lung injury. Am J Respir Cell Mol Biol 29: S77-81.
8. Ramsgaard L, Englert JM, Tobolewski J, Tomai L, Fattman CL, et al. (2010) The role of the receptor for advanced glycation end-products in a murine model of silicosis. PLoS One 5: e9604.
9. Shirasawa M, Fujiwara N, Hirabayashi S, Ohno H, Iida J, et al. (2004) Receptor for advanced glycation end-products is a marker of type 1 lung alveolar cells. Genes Cells 9: 165-174.
10. Demling N, Ehrhardt C, Kasper M, Laue M, Knels L, et al. (2006) Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells. Cell Tissue Res 323: 475-488.
11. He M, Kubo H, Ishizawa K, Hegab AE, Yamamoto Y, et al. (2007) The role of the receptor for advanced glycation end-products in lung fibrosis. Am J Physiol Lung Cell Mol Physiol 293: L1427-1436.
12. Li JH, Wang W, Huang XR, Oldfield M, Schmidt AM, et al. (2004) Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-ERK1/2 MAP kinase signaling pathway. Am J Pathol 164: 1389-1397.
13. Zhou Z, Wang K, Penn MS, Marso SP, Lauer MA, et al. (2003) Receptor for AGE (RAGE) mediates neointimal formation in response to arterial injury. Circulation 107: 2238-2243.
14. van Zoelen MA, Schouten M, de Vos AF, Florquin S, Meijers JC, et al. (2009) The receptor for advanced glycation end products impairs host defense in pneumococcal pneumonia. J Immunol 182: 4349-4356.
15. van Zoelen MA, Schmidt AM, Florquin S, Meijers JC, de Beer R, et al. (2009) Receptor for advanced glycation end products facilitates host defense during Escherichia coli-induced abdominal sepsis in mice. J Infect Dis 200: 765-773.
16. Zhang H, Tasaka S, Shiraishi Y, Fukunaga K, Yamada W, et al. (2008) Role of soluble receptor for advanced glycation end products on endotoxin-induced lung injury. Am J Respir Crit Care Med 178: 356-362.
17. Lizotte PP, Hanford LE, Enghild JJ, Nozik-Grayck E, Giles BL, et al. (2007) Developmental expression of the receptor for advanced glycation end-products (RAGE) and its response to hyperoxia in the neonatal rat lung. BMC Dev Biol 7: 15.
18. Uchida T, Shirasawa M, Ware LB, Kojima K, Hata Y, et al. (2006) Receptor for advanced glycation end-products is a marker of type 1 cell injury in acute lung injury. Am J Respir Crit Care Med 173: 1008-1015.
19. Calfee CS, Ware LB, Eisner MD, Parsons PE, Thompson BT, et al. (2008) Plasma receptor for advanced glycation end products and clinical outcomes in acute lung injury. Thorax 63: 1083-1089.
20. Wittkowski H, Sturrock A, van Zoelen MA, Viemann D, van der Poll T, et al. (2007) Neutrophil-derived S100A12 in acute lung injury and respiratory distress syndrome. Crit Care Med 35: 1369-1375.
21. Su X, Looney MR, Gupta N, Matthay MA, (2009) Receptor for Advanced Glycation End-products (RAGE) is an Indicator of Direct Lung Injury in Models of Experimental Lung Injury. Am J Physiol Lung Cell Mol Physiol.
22. Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, et al. (1999) Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11: 443-451.
23. Park JS, Gamboni-Robertson F, He Q, Svetkauskaite D, Kim JY, et al. (2006) High mobility group box 1 protein interacts with multiple Toll-like receptors. Am J Physiol Cell Physiol 290: C917-924.
24. Park JS, Svetkauskaite D, He Q, Kim JY, Strassheim D, et al. (2004) Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 279: 7370-7377.
25. Hori O, Brett J, Slattery T, Cao R, Zhang J, et al. (1995) The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J Biol Chem 270: 25752-25761.
26. Huttunen HJ, Fages C, Rauvala H, (1999) Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways. J Biol Chem 274: 19919-19924.
27. Schmidt AM, Hori O, Cao R, Yan SD, Brett J, et al. (1996) RAGE: a novel cellular receptor for advanced glycation end products. Diabetes 45 (Suppl 3): S77-80.
28. Janeway CA Jr, Medzhitov R, (2002) Innate immune recognition. Annu Rev Immunol 20: 197-216.
29. Constien R, Forde A, Liliensiek B, Grone HJ, Nawroth P, et al. (2001) Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line. Genesis 30: 36-44.
30. Renard C, Chappey O, Wautier MP, Nagashima M, Lundh E, et al. (1997) Recombinant advanced glycation end product receptor pharmacokinetics in normal and diabetic rats. Mol Pharmacol 52: 54-62.
31. Englert JM, Ramsgaard L, Valnickova Z, Enghild JJ, Oury TD, (2008) Large scale isolation and purification of soluble RAGE from lung tissue. Protein Expr Purif 61: 99-101.
32. Liu R, Mori S, Wake H, Zhang J, Liu K, et al. (2009) Establishment of in vitro binding assay of high mobility group box-1 and S100A12 to receptor for advanced glycation endproducts: heparin's effect on binding. Acta Med Okayama 63: 203-211.
33. Longmuir IS, Bourke A, (1960) The measurement of the diffusion of oxygen through respiring tissue. Biochem J 76: 225-229.
34. Freeman BA, O'Neil JJ, (1984) Tissue slices in the study of lung metabolism and toxicology. Environ Health Perspect 56: 51-60.
35. Bury AF, (1981) Analysis of protein and peptide mixtures Evaluation of three sodium dodecyl sulphate-polyacrylamide gel electrophoresis buffer systems. Journal of Chromatography A 213: 491-500.
36. Gefter JV, Shaufl AL, Fink MP, Delude RL, (2009) Comparison of distinct protein isoforms of the receptor for advanced glycation end-products expressed in murine tissues and cell lines. Cell Tissue Res 337: 79-89.
37. Hofmann MA, Drury S, Fu C, Qu W, Taguchi A, et al. (1999) RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 97: 889-901.
38. Park L, Raman KG, Lee KJ, Lu Y, Ferran LJ Jr, et al. (1998) Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts. Nat Med 4: 1025-1031.
39. Chen Y, Yan SS, Colgan J, Zhang HP, Luban J, et al. (2004) Blockade of late stages of autoimmune diabetes by inhibition of the receptor for advanced glycation end products. J Immunol 173: 1399-1405.
40. Zeng S, Feirt N, Goldstein M, Guarrera J, Ippagunta N, et al. (2004) Blockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury to the liver in mice. Hepatology 39: 422-432.
41. Brett J, Schmidt AM, Yan SD, Zou YS, Weidman E, et al. (1993) Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues. Am J Pathol 143: 1699-1712.
42. Englert JM, Kliment CR, Ramsgaard L, Milutinovic PS, Crum L, et al. (2011) Paradoxical function for the receptor for advanced glycation end products in mouse models of pulmonary fibrosis. Int J Clin Exp Pathol 4.
43. Liliensiek B, Weigand MA, Bierhaus A, Nicklas W, Kasper M, et al. (2004) Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response. J Clin Invest 113: 1641-1650.
44. Park WY, Goodman RB, Steinberg KP, Ruzinski JT, Radella F 2nd, et al. (2001) Cytokine balance in the lungs of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 164: 1896-1903.
45. Mukhopadhyay S, Hoidal JR, Mukherjee TK, (2006) Role of TNFalpha in pulmonary pathophysiology. Respir Res 7: 125.
46. Baggiolini M, Loetscher P, Moser B, (1995) Interleukin-8 and the chemokine family. Int J Immunopharmacol 17: 103-108.
47. Feng Y, Yang Q, Xu J, Qian G, Liu Y, (2008) Effects of HMGB1 on PMN apoptosis during LPS-induced acute lung injury. Exp Mol Pathol 85: 214-222.
48. Kim JY, Park JS, Strassheim D, Douglas I, Diaz del Valle F, et al. (2005) HMGB1 contributes to the development of acute lung injury after hemorrhage. Am J Physiol Lung Cell Mol Physiol 288: L958-965.
49. Blackwell TS, Lancaster LH, Blackwell TR, Venkatakrishnan A, Christman JW, (1999) Chemotactic gradients predict neutrophilic alveolitis in endotoxin-treated rats. Am J Respir Crit Care Med 159: 1644-1652.