Effect of annealing time and addition of lactose on release of a model substance from Eudragit® RS coated pellets produced by a fluidized bed coater

Chemical Engineering Research and Design

Volumn 89, Issue 6, 2011, Pages 697-705

  Heckötter, Ulrich M ^a,b   Larsson, Anette ^b   Sriamornsak, Pornsak ^a,c   Kumpugdee Vollrath, Mont ^a  

^a Institut für Soziale Gesundheit Katholische Hochschule für Sozialwesen Berlin   (Germany)

^b CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^c SILPAKORN UNIVERSITY   (Thailand)

Author keywords

Annealing; Eudragit RS 30 D; Film coating; Fluidized bed coating; Lactose; Pellets

Indexed keywords

ANNEALING TIME; AQUEOUS DISPERSIONS; COATING PROCESS; DRUG RELEASE; EUDRAGIT; FILM COATING; FLUIDIZED BED COATING; LACTOSE; LAG PERIOD; LIQUID FORMULATIONS; METHYLENE BLUE; MICROCRYSTALLINE CELLULOSE; MODEL SUBSTANCE; PELLETS; RELEASE PROFILES; SCANNING ELECTRON MICROSCOPE;

ANNEALING; COATINGS; FLUIDIZATION; FLUIDIZED BEDS; PELLETIZING; SCANNING ELECTRON MICROSCOPY; SUGARS;

FLUIDIZED BED PROCESS;

EID: 79956325564     PISSN: 02638762     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cherd.2010.09.016     Document Type: Article

References (27)

1. Aulton M.E. Pharmaceutics-The Science of Dosage Form Design 2002, Churchill Livingstone, London, UK.
2. Bodmeier R., Paeratakul O. The effect of curing on drug release and morphological properties of ethylcellulose pseudolatexcoated beads. Drug. Dev. Ind. Pharm. 1994, 20:1517-1533.
3. Chevalier Y., Pichot C., Graillat C., Joanicot M., Wong K., Lindner P., Cabane B. Film formation with latex particles. Colloid Polym. Sci. 1992, 270:806-821.
4. Chopra R., Alderborn G., Newton J.M., Podczeck F. The influence of film coating on pellet properties. Pharm. Dev. Technol. 2002, 7:59-68.
5. Dobler F., Holl Y. Mechanisms of latex film formation. Trends Polym. Sci. 1996, 4:272-279.
6. Fukumori Y. Coating of multiparticulates using polymeric dispersions. Multiparticulate Oral Drug Delivery 1994, 79-111. Marcel Dekker, New York, USA. I. Ghebre-Sellassie (Ed.).
7. Gilligan C.A., Li Wan Po A. Factors affecting drug release from a pellet system coated with an aqueous colloidal dispersion. Int. J. Pharm. 1991, 73:51-68.
8. Keshikawa T., Nakagami H. Film formation with coating systems of aqueous suspensions and latex dispersions of ethylcellulose. Chem. Pharm. Bull. 1994, 42:656-662.
9. Kibria G., Islam S., Jalil R. Comparative study of aqueous dispersion of different types of polymers on release behavior of salbumatol sulphate from coated tablets. J. Pharm. Sci. Res. 2010, 2:107-115.
10. Lehmann K.O. Chemistry and application properties of polymethacrylate coating systems. Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms 1989, 153-245. Marcel Dekker, New York, USA. J.W. McGinity (Ed.).
11. McGinity J.W. Aqueous polymeric coatings for pharmaceutical dosage forms 1997, Marcel Dekker, New York, USA. 2nd edn.
12. Mendoza-Romero L., Piñón-Segundo E., Nava-Arzaluz M.G., Ganem-Quintanar A., Cordero-Sánchez S., Quintanar-Guerrero D. Comparison of pharmaceutical films prepared from aqueous polymeric dispersions using the cast method and the spraying technique. Colloids Surf. A 2009, 337:109-116.
13. Narisawa S., Nagata M., Hirakawa Y., Kobayashi M., Yoshino H. An organic acid-induced sigmoidal release system for oral controlled-release preparations. III. Elucidation of the anomalous drug release behavior through osmotic pumping mechanism. Int. J. Pharm. 1997, 148:85-91.
14. Parikh D., Bonck J. Batch fluid bed granulation. Handbook of Pharmaceutical Granulation Technology 1997, 227-302. Marcel Dekker, New York, USA. D. Parikh (Ed.).
15. Petereit H.U., Weisbrod W. Formulation and process considerations affecting the stability of solid dosage forms formulated with methacrylate copolymers. Eur. J. Pharm. Biopharm. 1999, 47:15-25.
16. Ragnarsson G., Sandberg A., Johansson M., Lindstedt B., Sjörgren J. In-vitro release characteristics of a membrane-coated pellet formulation-influence of drug solubility and particle size. Int. J. Pharm. 1992, 79:223-232.
17. Rhodes C.T., Porter S.C. Coating of controlled-release drug delivery systems. Drug Dev. Ind. Pharm. 1998, 24:1139-1154.
18. Ringqvist A., Taylor L.S., Ekelund K., Ragnarsson G., Engström S., Axelsson A. Atomic force microscopy analysis and confocal Raman microimaging of coated pellets. Int. J. Pharm. 2003, 267:35-47.
19. Sriamornsak P., Nunthanid J., Wanchana S., Luangtana-Anan M. Composite film coated tablets intended for colon-specific delivery of 5-aminosalicylic acid: using deesterified pectin. Pharm. Dev. Technol. 2003, 8:311-318.
20. Steward P.A., Hearn J., Wilkinson M.C. An overview of polymer latex film formation and properties. Adv. Colloid Interface Sci. 2000, 86:195-267.
21. Winnik M. Latex film formation. Curr. Opin. Colloid Interface Sci. 1997, 2:192-199.
22. Wu, C., McGinity, J.W., 2001. Influence of ibuprofen as a solid-state plasticizer in Eudragit® RS 30 D on the physicochemical properties of coated beads. AAPS Pharm. Sci. Tech. 2: article 24.
23. Wurster D.E. Particle-coating methods. Pharmaceutical Dosage Forms-Tablets 1990, vol. 3:161-198. Marcel Dekker, New York, USA. 2nd edition.
24. Wurster, D.E., Bhattacharja, S., Flanagan, D.R., 2007. Effect of curing on water diffusivities in acrylate free films as measured via a sorption technique. AAPS Pharm. Sci. Tech. 8: article 71.
25. Yang Q.W., Flament M.P., Siepmann F., Busignies V., Leclerc B., Herry C., Tchoreloff P., Siepmann J. Curing of aqueous polymeric film coatings: importance of the coating level and type of plasticizer. Eur. J. Pharm. Biopharm. 2010, 74:362-370.
26. ® L 30 D-55. Chem. Pharm. Bull. 2007, 55:1261-1263.
27. Zohrehvand S., Nijenhuis K. Film formation from monodisperse acrylic latices: 5. Drying and ageing in coalescing agent containing latex films. J. Colloid Interface Sci. 2005, 288:75-82.