An organic acid-induced sigmoidal release system for oral controlled-release preparations. III. Elucidation of the anomalous drug release behavior through osmotic pumping mechanism

International Journal of Pharmaceutics

Volumn 148, Issue 1, 1997, Pages 85-91

  Narisawa, Shinji ^a   Nagata, Minako ^a   Hirakawa, Yoshiyuki ^a   Kobayashi, Masao ^a   Yoshino, Hiroyuki ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Acid polymer interaction; Drug release mechanism; Eudragit RS; Osmotic pumping; Sigmoidal release system

Indexed keywords

EUDRAGIT RS; POLYMER; THEOPHYLLINE;

ARTICLE; CONTROLLED RELEASE FORMULATION; DISSOLUTION; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; OSMOTIC PRESSURE; OSMOTIC PUMP; PRIORITY JOURNAL;

EID: 0030984248     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(96)04834-X     Document Type: Article

References (13)

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