Onset and organ specificity of Tk2 deficiency depends on Tk1 down-regulation and transcriptional compensation

Human Molecular Genetics

Volumn 20, Issue 1, 2011, Pages 155-164

  Dorado, Beatriz ^a   Area, Estela ^a   Akman, Hasan O ^a   Hirano, Michio ^a  

^a New York Presbyterian Morgan Stanley Children's Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GA BINDING PROTEIN; MITOCHONDRIAL TRANSCRIPTIONAL TERMINATOR TRANSCRIPTION FACTOR 3; NUCLEAR RESPIRATORY FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; THYMIDINE KINASE; THYMIDINE KINASE 2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; MTERF PROTEIN, MOUSE; PPARGC1A PROTEIN, MOUSE; THYMIDINE KINASE 1; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOGENESIS; BRAIN; CONTROLLED STUDY; DISEASE SEVERITY; DOWN REGULATION; ENCEPHALOMYOPATHY; HEART; MITOCHONDRIAL DNA DEPLETION; MOUSE; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION; UPREGULATION; WILD TYPE; ANIMAL; ANTIBODY SPECIFICITY; DISEASE MODEL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENE TARGETING; GENETICS; MITOCHONDRIAL ENCEPHALOMYOPATHY; MUSCLE DISEASE; ONSET AGE; PATHOLOGY;

MUS;

AGE OF ONSET; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; DNA, MITOCHONDRIAL; DOWN-REGULATION; GENE EXPRESSION REGULATION; GENE KNOCK-IN TECHNIQUES; HEART; MICE; MITOCHONDRIAL ENCEPHALOMYOPATHIES; MITOCHONDRIAL PROTEINS; MUSCULAR DISEASES; ORGAN SPECIFICITY; THYMIDINE KINASE; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 79956319776     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq453     Document Type: Article

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