Human thymidine kinase 2: Molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substrates

FEBS Letters

Volumn 443, Issue 2, 1999, Pages 170-174

  Wang, Liya ^a   Munch Petersen, Birgitte ^b   Herrström Sjöberg, Anita ^a   Hellman, Ulf ^c   Bergman, Tomas ^d   Jörnvall, Hans ^d   Eriksson, Staffan ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b ROSKILDE UNIVERSITY   (Denmark)

^c UPPSALA UNIVERSITY   (Sweden)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Antiviral nucleoside; Cloning; Cytostatic nucleoside; Metabolic conversion; Mitochondrial enzyme; Thymidine kinase

Indexed keywords

ANTIVIRUS AGENT; CYTARABINE; CYTOSTATIC AGENT; DEOXYCYTIDINE; GEMCITABINE; MITOCHONDRIAL ENZYME; NUCLEOSIDE DERIVATIVE; THYMIDINE; THYMIDINE KINASE; THYMINE DERIVATIVE; ZIDOVUDINE;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; METABOLIC ACTIVATION; MITOCHONDRION; MOLECULAR CLONING; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; CLONING, MOLECULAR; DNA, COMPLEMENTARY; HUMANS; MOLECULAR SEQUENCE DATA; SUBSTRATE SPECIFICITY; THYMIDINE KINASE;

EID: 0032994472     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)01711-6     Document Type: Article

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