Altered gene transcription profiles in fibroblasts harboring either TK2 or DGUOK mutations indicate compensatory mechanisms

Experimental Cell Research

Volumn 315, Issue 8, 2009, Pages 1429-1438

  Villarroya, Joan ^a,b   de Bolós, Carme ^c   Meseguer, Anna ^a   Hirano, Michio ^d   Vilà, Maya R ^a  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c HOSPITAL DEL MAR   (Spain)

^d Department of Medicine   (United States)

Author keywords

Fibroblasts; hENT1; Mitochondrial dNTP pools; mtDNA depletion; TK2

Indexed keywords

DEOXYGUANOSINE KINASE; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1; MESSENGER RNA; MITOCHONDRIAL DNA; PROTEIN; SMALL INTERFERING RNA; THYMIDINE KINASE; THYMIDINE KINASE 2; THYMIDINE PHOSPHORYLASE; THYMIDYLATE SYNTHASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADOLESCENT; ARTICLE; CASE REPORT; CELL CYCLE; CHILD; CONTROLLED STUDY; DOWN REGULATION; FIBROBLAST; GENE MUTATION; GENETIC TRAIT; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MITOCHONDRIAL DNA DEPLETION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHOOL CHILD; WESTERN BLOTTING;

EID: 64049092047     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2009.02.018     Document Type: Article

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