Bromovinyl-deoxyuridine: A selective substrate for mitochondrial thymidine kinase in cell extracts

Biochemical and Biophysical Research Communications

Volumn 344, Issue 1, 2006, Pages 30-36

  Franzolin, Elisa ^a   Rampazzo, Chiara ^a   Pérez Pérez, María Jesús ^b   Hernández, Ana Isabel ^b   Balzarini, Jan ^c   Bianchi, Vera ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b INSTITUTO DE QUÍMICA MÉDICA   (Spain)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Enzyme assays; Mitochondrial diseases; Mitochondrial DNA depletion syndromes; Mitochondrial DNA precursors; Thymidine analogs; Thymidine kinase 2; TK2 inhibitors; TK2 deficiency

Indexed keywords

1 [6 [1,1 (DIPHENYL) 1 (4 PYRIDYL)METHOXY]HEXYL]THYMINE; 5 (2 BROMOVINYL) 2' DEOXYURIDINE; CELL EXTRACT; THYMIDINE KINASE; THYMIDINE KINASE INHIBITOR; THYMINE ARABINOSIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SUBSTRATE; FIBROBLAST; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; MITOCHONDRION; OSTEOSARCOMA CELL; PRIORITY JOURNAL;

ARABINONUCLEOSIDES; BIOLOGICAL ASSAY; BROMODEOXYURIDINE; CELL EXTRACTS; FIBROBLASTS; HUMANS; MITOCHONDRIA; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; SUBSTRATE SPECIFICITY; THYMIDINE; THYMIDINE KINASE; TUMOR CELLS, CULTURED;

ARA;

EID: 33646039798     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.03.147     Document Type: Article

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