Engineering of insulin receptor isoform-selective insulin analogues

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Glendorf, Tine ^a   Stidsen, Carsten E ^a   Norrman, Mathias ^a   Nishimura, Erica ^a   Sørensen, Anders R ^a   Kjeldsen, Thomas ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN INSULIN; INSULIN DERIVATIVE; INSULIN RECEPTOR; DRUG DERIVATIVE; INSULIN; ISOPROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; GENE MUTATION; IC 50; NONHUMAN; PROTEIN ENGINEERING; RECEPTOR BINDING; TISSUE SPECIFICITY; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MUTAGENESIS; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; HUMANS; INSULIN; MUTAGENESIS; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN ISOFORMS; RECEPTOR, INSULIN;

EID: 79956296608     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020288     Document Type: Article

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