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Volumn 79, Issue 6, 2011, Pages 1014-1022

Galangin suppresses the proliferation of β-catenin response transcription-positive cancer cells by promoting adenomatous polyposis coli/axin/glycogen synthase kinase-3β-independent β-catenin degradation

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; AXIN; BETA CATENIN; CYCLIN D1; GALANGIN; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROXYL GROUP; T CELL FACTOR PROTEIN;

EID: 79956296141     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.069591     Document Type: Article
Times cited : (43)

References (39)
  • 1
    • 0030978351 scopus 로고    scopus 로고
    • β-Catenin is a target for the ubiquitin-proteasome pathway
    • Aberle H, Bauer A, Stappert J, Kispert A, and Kemler R (1997) β-Catenin is a target for the ubiquitin-proteasome pathway. EMBO J 16:3797-3804.
    • (1997) EMBO J , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 2
    • 0027057155 scopus 로고
    • Synergistic effect of flavones and flavonols against herpes simplex virus type 1 in cell culture. Comparison with the antiviral activity of propolis
    • DOI 10.1021/np50090a003
    • Amoros M, Simões CM, Girre L, Sauvager F, and Cormier M (1992) Synergistic effect of flavones and flavonols against herpes simplex virus type 1 in cell culture. Comparison with the antiviral activity of propolis. J Nat Prod 55:1732-1740. (Pubitemid 23023259)
    • (1992) Journal of Natural Products (Lloydia) , vol.55 , Issue.12 , pp. 1732-1740
    • Amoros, M.1    Simoes, C.M.O.2    Girre, L.3    Sauvager, F.4    Cormier, M.5
  • 3
    • 33749240336 scopus 로고    scopus 로고
    • Influence of galangin on HL-60 cell proliferation and survival
    • DOI 10.1016/j.canlet.2005.11.025, PII S0304383505010256
    • Bestwick CS and Milne L (2006) Influence of galangin on HL-60 cell proliferation and survival. Cancer Lett 243:80-89. (Pubitemid 44485322)
    • (2006) Cancer Letters , vol.243 , Issue.1 , pp. 80-89
    • Bestwick, C.S.1    Milne, L.2
  • 5
    • 23744505379 scopus 로고    scopus 로고
    • Diclofenac attenuates Wnt/β-catenin signaling in colon cancer cells by activation of NF-κB
    • DOI 10.1016/j.febslet.2005.06.049, PII S0014579305007945
    • Cho M, Gwak J, Park S, Won J, Kim DE, Yea SS, Cha IJ, Kim TK, Shin JG, and Oh S (2005) Diclofenac attenuates Wnt/β-catenin signaling in colon cancer cells by activation of NF-κB. FEBS Lett 579:4213-4218. (Pubitemid 41121964)
    • (2005) FEBS Letters , vol.579 , Issue.20 , pp. 4213-4218
    • Cho, M.1    Gwak, J.2    Park, S.3    Won, J.4    Kim, D.-E.5    Sung, S.Y.6    Cha, I.-J.7    Tae, K.K.8    Shin, J.-G.9    Oh, S.10
  • 6
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, and Roeder RG (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 9
    • 0034760407 scopus 로고    scopus 로고
    • β-catenin antisense treatment decreases β-catenin expression and tumor growth rate in colon carcinoma xenografts
    • DOI 10.1006/jsre.2001.6241
    • Green DW, Roh H, Pippin JA, and Drebin JA (2001) β-Catenin antisense treatment decreases β-catenin expression and tumor growth rate in colon carcinoma xenografts. J Surg Res 101:16-20. (Pubitemid 33030101)
    • (2001) Journal of Surgical Research , vol.101 , Issue.1 , pp. 16-20
    • Green, D.W.1    Roh, H.2    Pippin, J.A.3    Drebin, J.A.4
  • 11
    • 0032492954 scopus 로고    scopus 로고
    • Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β
    • Hart MJ, de los Santos R, Albert IN, Rubinfeld B, and Polakis P (1998) Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β. Curr Biol 8:573-581.
    • (1998) Curr Biol , vol.8 , pp. 573-581
    • Hart, M.J.1    De Los Santos, R.2    Albert, I.N.3    Rubinfeld, B.4    Polakis, P.5
  • 12
    • 0033615352 scopus 로고    scopus 로고
    • PPARδ is an APC-regulated target of nonsteroidal anti-inflammatory drugs
    • DOI 10.1016/S0092-8674(00)81664-5
    • He TC, Chan TA, Vogelstein B, and Kinzler KW (1999) PPARδ is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell 99:335-345. (Pubitemid 29519912)
    • (1999) Cell , vol.99 , Issue.3 , pp. 335-345
    • He, T.-C.1    Chan, T.A.2    Vogelstein, B.3    Kinzler, K.W.4
  • 14
    • 0035022576 scopus 로고    scopus 로고
    • Anti-genotoxicity of galangin as a cancer chemopreventive agent candidate
    • DOI 10.1016/S1383-5742(01)00054-0, PII S1383574201000540
    • Heo MY, Sohn SJ, and Au WW (2001) Anti-genotoxicity of galangin as a cancer chemopreventive agent candidate. Mutat Res 488:135-150. (Pubitemid 32436428)
    • (2001) Mutation Research - Reviews in Mutation Research , vol.488 , Issue.2 , pp. 135-150
    • Heo, M.Y.1    Sohn, S.J.2    Au, W.W.3
  • 15
    • 0026443919 scopus 로고
    • Anticlastogenic effect of flavonoids against mutagen-induced micronuclei in mice
    • Heo MY, Yu KS, Kim KH, Kim HP, and Au WW (1992) Anticlastogenic effect of flavonoids against mutagen-induced micronuclei in mice. Mutat Res 284:243-249.
    • (1992) Mutat Res , vol.284 , pp. 243-249
    • Heo, M.Y.1    Yu, K.S.2    Kim, K.H.3    Kim, H.P.4    Au, W.W.5
  • 17
    • 0032473355 scopus 로고    scopus 로고
    • Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin
    • DOI 10.1093/emboj/17.5.1371
    • Ikeda S, Kishida S, Yamamoto H, Murai H, Koyama S, and Kikuchi A (1998) Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin. EMBO J 17:1371-1384. (Pubitemid 28105516)
    • (1998) EMBO Journal , vol.17 , Issue.5 , pp. 1371-1384
    • Ikeda, S.1    Kishida, S.2    Yamamoto, H.3    Murai, H.4    Koyama, S.5    Kikuchi, A.6
  • 19
    • 0034087719 scopus 로고    scopus 로고
    • Inhibitory effects of flavonoids on rabbit heart carbonyl reductase
    • Imamura Y, Migita T, Uriu Y, Otagiri M, and Okawara T (2000) Inhibitory effects of flavonoids on rabbit heart carbonyl reductase. J Biochem 127:653-658. (Pubitemid 30238359)
    • (2000) Journal of Biochemistry , vol.127 , Issue.4 , pp. 653-658
    • Imamura, Y.1    Migita, T.2    Uriu, Y.3    Otagiri, M.4    Okawara, T.5
  • 20
    • 1942537708 scopus 로고    scopus 로고
    • The significance of the Wnt pathway in the pathology of human cancers
    • DOI 10.1080/00313020410001671957
    • Karim R, Tse G, Putti T, Scolyer R, and Lee S (2004) The significance of the Wnt pathway in the pathology of human cancers. Pathology 36:120-128. (Pubitemid 38507872)
    • (2004) Pathology , vol.36 , Issue.2 , pp. 120-128
    • Karim, R.Z.1    Tse, G.M.K.2    Putti, T.C.3    Scolyer, R.A.4    Lee, C.S.5
  • 22
    • 0035947083 scopus 로고    scopus 로고
    • Siah-1 mediates a novel β-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein
    • DOI 10.1016/S1097-2765(01)00241-6
    • Liu J, Stevens J, Rote CA, Yost HJ, Hu Y, Neufeld KL, White RL, and Matsunami N (2001) Siah-1 mediates a novel β-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein. Mol Cell 7:927-936. (Pubitemid 32525740)
    • (2001) Molecular Cell , vol.7 , Issue.5 , pp. 927-936
    • Liu, J.1    Stevens, J.2    Rote, C.A.3    Yost, H.J.4    Hu, Y.5    Neufeld, K.L.6    White, R.L.7    Matsunami, N.8
  • 23
    • 0035947080 scopus 로고    scopus 로고
    • Siah-1, SIP, and Ebi collaborate in a novel pathway for β-catenin degradation linked to p53 responses
    • Matsuzawa SI and Reed JC (2001) Siah-1, SIP, and Ebi collaborate in a novel pathway for β-catenin degradation linked to p53 responses. Mol Cell 7:915-926.
    • (2001) Mol Cell , vol.7 , pp. 915-926
    • Matsuzawa, S.I.1    Reed, J.C.2
  • 24
    • 0032525836 scopus 로고    scopus 로고
    • Activation of the β-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3
    • Miyoshi Y, Iwao K, Nagasawa Y, Aihara T, Sasaki Y, Imaoka S, Murata M, Shimano T, and Nakamura Y (1998) Activation of the β-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Res 58:2524-2527. (Pubitemid 28275419)
    • (1998) Cancer Research , vol.58 , Issue.12 , pp. 2524-2527
    • Miyoshi, Y.1    Iwao, K.2    Nagasawa, Y.3    Aihara, T.4    Sasaki, Y.5    Imaoka, S.6    Murata, M.7    Shimano, T.8    Nakamura, Y.9
  • 25
    • 0033486152 scopus 로고    scopus 로고
    • β-Catenin signaling and cancer
    • Morin PJ (1999) β-Catenin signaling and cancer. Bioessays 21:1021-1030.
    • (1999) Bioessays , vol.21 , pp. 1021-1030
    • Morin, P.J.1
  • 26
    • 33746564251 scopus 로고    scopus 로고
    • Growth of a human mammary tumor cell line is blocked by galangin, a naturally occurring bioflavonoid, and is accompanied by down-regulation of cyclins D3, E, and A
    • Murray TJ, Yang X, and Sherr DH (2006) Growth of a human mammary tumor cell line is blocked by galangin, a naturally occurring bioflavonoid, and is accompanied by down-regulation of cyclins D3, E, and A. Breast Cancer Res 8:R17.
    • (2006) Breast Cancer Res , vol.8
    • Murray, T.J.1    Yang, X.2    Sherr, D.H.3
  • 28
    • 33747597785 scopus 로고    scopus 로고
    • Hexachlorophene inhibits Wnt/β-catenin pathway by promoting Siah-mediated β-catenin degradation
    • DOI 10.1124/mol.106.024729
    • Park S, Gwak J, Cho M, Song T, Won J, Kim DE, Shin JG, and Oh S (2006) Hexachlorophene inhibits Wnt/β-catenin pathway by promoting Siah-mediated β-catenin degradation. Mol Pharmacol 70:960-966. (Pubitemid 44268452)
    • (2006) Molecular Pharmacology , vol.70 , Issue.3 , pp. 960-966
    • Park, S.1    Gwak, J.2    Cho, M.3    Song, T.4    Won, J.5    Kim, D.-E.6    Shin, J.-G.7    Oh, S.8
  • 29
    • 0034053069 scopus 로고    scopus 로고
    • Wnt signaling in oncogenesis and embryogenesis - A look outside the nucleus
    • DOI 10.1126/science.287.5458.1606
    • Peifer M and Polakis P (2000) Wnt signaling in oncogenesis and embryogenesis-a look outside the nucleus. Science 287:1606-1609. (Pubitemid 30127755)
    • (2000) Science , vol.287 , Issue.5458 , pp. 1606-1609
    • Peifer, M.1    Polakis, P.2
  • 30
    • 0033851905 scopus 로고    scopus 로고
    • The bioflavonoid galangin blocks aryl hydrocarbon receptor activation and polycyclic aromatic hydrocarbon-induced pre-B cell apoptosis
    • Quadri SA, Qadri AN, Hahn ME, Mann KK, and Sherr DH (2000) The bioflavonoid galangin blocks aryl hydrocarbon receptor activation and polycyclic aromatic hydrocarbon-induced pre-B cell apoptosis. Mol Pharmacol 58:515-525.
    • (2000) Mol Pharmacol , vol.58 , pp. 515-525
    • Quadri, S.A.1    Qadri, A.N.2    Hahn, M.E.3    Mann, K.K.4    Sherr, D.H.5
  • 31
    • 0035420212 scopus 로고    scopus 로고
    • Suppression of β-catenin inhibits the neoplastic growth of APC-mutant colon cancer cells
    • Roh H, Green DW, Boswell CB, Pippin JA, and Drebin JA (2001) Suppression of β-catenin inhibits the neoplastic growth of APC-mutant colon cancer cells. Cancer Res 61:6563-6568. (Pubitemid 32783265)
    • (2001) Cancer Research , vol.61 , Issue.17 , pp. 6563-6568
    • Roh, H.1    Green, D.W.2    Boswell, C.B.3    Pippin, J.A.4    Drebin, J.A.5
  • 32
    • 56349116715 scopus 로고    scopus 로고
    • Natural derivatives of curcumin attenuate the Wnt/β-catenin pathway through down-regulation of the transcriptional coactivator p300
    • Ryu MJ, Cho M, Song JY, Yun YS, Choi IW, Kim DE, Park BS, and Oh S (2008) Natural derivatives of curcumin attenuate the Wnt/β-catenin pathway through down-regulation of the transcriptional coactivator p300. Biochem Biophys Res Commun 377:1304-1308.
    • (2008) Biochem Biophys Res Commun , vol.377 , pp. 1304-1308
    • Ryu, M.J.1    Cho, M.2    Song, J.Y.3    Yun, Y.S.4    Choi, I.W.5    Kim, D.E.6    Park, B.S.7    Oh, S.8
  • 33
    • 4143065010 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ activation can regulate β-catenin levels via a proteasome-mediated and adenomatous polyposis coli-independent pathway
    • DOI 10.1074/jbc.M403143200
    • Sharma C, Pradeep A, Wong L, Rana A, and Rana B (2004) Peroxisome proliferator-activated receptor γ activation can regulate β-catenin levels via a proteasome-mediated and adenomatous polyposis coli-independent pathway. J Biol Chem 279:35583-35594. (Pubitemid 39100560)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.34 , pp. 35583-35594
    • Sharma, C.1    Pradeep, A.2    Wong, L.3    Rana, A.4    Rana, B.5
  • 34
    • 0037194578 scopus 로고    scopus 로고
    • Identification of membrane-type matrix metalloproteinase-1 as a target of the β-catenin/Tcf4 complex in human colorectal cancers
    • DOI 10.1038/sj.onc.1205755
    • Takahashi M, Tsunoda T, Seiki M, Nakamura Y, and Furukawa Y (2002) Identification of membrane-type matrix metalloproteinase-1 as a target of the β-catenin/Tcf4 complex in human colorectal cancers. Oncogene 21:5861-5867. (Pubitemid 35007236)
    • (2002) Oncogene , vol.21 , Issue.38 , pp. 5861-5867
    • Takahashi, M.1    Tsunoda, T.2    Seiki, M.3    Nakamura, Y.4    Furukawa, Y.5
  • 35
    • 0033119801 scopus 로고    scopus 로고
    • β-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • DOI 10.1038/18884
    • Tetsu O and McCormick F (1999) β-Catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398:422-426. (Pubitemid 29180374)
    • (1999) Nature , vol.398 , Issue.6726 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 36
    • 0037388638 scopus 로고    scopus 로고
    • Small interfering RNAs directed against β-catenin inhibit the in vitro and in vivo growth of colon cancer cells
    • Verma UN, Surabhi RM, Schmaltieg A, Becerra C, and Gaynor RB (2003) Small interfering RNAs directed against β-catenin inhibit the in vitro and in vivo growth of colon cancer cells. Clin Cancer Res 9:1291-1300. (Pubitemid 36418379)
    • (2003) Clinical Cancer Research , vol.9 , Issue.4 , pp. 1291-1300
    • Verma, U.N.1    Surabhi, R.M.2    Schmaltieg, A.3    Becerra, C.4    Gaynor, R.B.5
  • 39
    • 0031785065 scopus 로고    scopus 로고
    • Comparative inhibition of human cytochromes P450 1A1 and 1A2 by flavonoids
    • Zhai S, Dai R, Friedman FK, and Vestal RE (1998) Comparative inhibition of human cytochromes P450 1A1 and 1A2 by flavonoids. Drug Metab Dispos 26:989-992. (Pubitemid 28478260)
    • (1998) Drug Metabolism and Disposition , vol.26 , Issue.10 , pp. 989-992
    • Zhai, S.1    Dai, R.2    Friedman, F.K.3    Vestal, R.E.4


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