In vitro characterization and in vivo analgesic and anti-allodynic activity of PLGA-bupivacaine nanoparticles

Journal of Nanoparticle Research

Volumn 13, Issue 5, 2011, Pages 2213-2223

  Garcia, Xavier ^a   Escribano, Elvira ^a   Domenech, Josep ^a   Queralt, Josep ^a   Freixes, Joan ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Antiallodynia; Antinociception; Bupivacaine; In vitro release; Korsmeyer Peppas; Modeling and simulation; Nanomedicine; PLGA nanoparticles

Indexed keywords

ANTIALLODYNIA; ANTINOCICEPTION; BUPIVACAINE; IN VITRO RELEASE; KORSMEYER-PEPPAS; MODELING AND SIMULATION; NANOMEDICINES; PLGA NANOPARTICLES;

ANESTHETICS; COMPUTER SIMULATION; DISSOLUTION; EMULSIFICATION; EMULSIONS; ENCAPSULATION; HEALTH; MEDICAL NANOTECHNOLOGY; RATS;

NANOPARTICLES;

BUPIVACAINE; POLYGLACTIN;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG RELEASE; DRUG SOLUBILITY; EVAPORATION; IN VITRO STUDY; IN VIVO STUDY; MALE; NANOEMULSION; NANOENCAPSULATION; NERVE INJURY; NOCICEPTION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; SCIATIC NERVE INJURY; SUSTAINED DRUG RELEASE;

EID: 79956290523     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-010-9979-1     Document Type: Article

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