Evaluation of the efficacy of a bioerodible bupivacaine polymer system on antinociception and inflammatory mediator release

Pain

Volumn 82, Issue 1, 1999, Pages 49-55

  Garry, Mary G ^a   Jackson, Douglass L ^a   Geier, Heidi E ^a   Southam, Mary ^b   Hargreaves, Kenneth M ^a,c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b ALZA CORPORATION   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Antinociception; Bioerodible bupivacaine polymer system; Hyperalgesia

Indexed keywords

BRADYKININ; BUPIVACAINE; POLYMER; SUBSTANCE P;

ALLODYNIA; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EDEMA; HYPERALGESIA; INFLAMMATION; INTRADERMAL DRUG ADMINISTRATION; MALE; MEDIATOR RELEASE; MICRODIALYSIS; NONHUMAN; PAIN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; SUSTAINED DRUG RELEASE; TISSUE INJURY;

ANESTHETICS, LOCAL; ANIMALS; BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; BRADYKININ; BUPIVACAINE; DRUG IMPLANTS; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; LACTIC ACID; MALE; MICRODIALYSIS; PAIN; POLYGLYCOLIC ACID; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANCE P;

EID: 0033061523     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(99)00032-9     Document Type: Article

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