Pain from the arthritic joint

Synaptic Plasticity in Pain

Volumn , Issue , 2009, Pages 271-288

  Schaible, Hans Georg ^a   Ebersberger, Andrea ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79956284448     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4419-0226-9_12     Document Type: Chapter

References (74)

1. Abbadie C, Besson J-M (1992) C-fos expression in rat lumbar spinal cord during the development of adjuvant-induced arthritis. Neuroscience 48:985-993.
2. Andreeva L, Rang HP (1993) Effect of bradykinin and prostaglandins on the release of calcitonin gene-related peptide-like immunoreactivity from the rat spinal cord in vitro. Br J Pharmacol 108:185-190.
3. Arendt-Nielsen L, Laursen RJ, Drewes AM (2000) Referred pain as an indicator for neural plasticity. In: J Sandkühler, B Bromm, GF Gebhart (Eds) Progress in Brain Research, vol. 129. Elsevier, Amsterdam, pp. 343-356.
4. Bajaj P, Bajaj P, Graven-Nielsen T, Arendt-Nielsen L (2001) Osteoarthritis and its association with muscle hyperalgesia: an experimental controlled study. Pain 93:107-114.
5. Bar K-J, Natura G, Telleria-Diaz A, Teschner P, Vogel R, Vasquez E, Schaible H-G, Ebersberger A (2004) Changes in the effect of spinal prostaglandin E2 during inflammation - Prostaglandin E (EP1-EP4) receptors in spinal nociceptive processing of input from the normal or inflamed knee joint. J Neurosci 24:642-651.
6. Barnes PJ, Karin M (1997) Nuclear factor-κB - a pivotal transcription factor in chronic inflammatory diseases. New Engl J Med 336:1066-1071.
7. Boettger MK, Hensellek S, Richter F, Gajda M, Stockigt R, Segond von Banchet G, Brauer R, Schaible H-G (2008) Antinociceptive effects of TNF-a neutralization in a rat model of antigen-induced arthritis. Evidence for a neuronal target. Arthritis Rheum 58:2368-2378.
8. Calvino B, Villanueva L, LeBars D (1987) Dorsal horn (convergent) neurones in the intact anaesthetized arthritic rat. II. Heterotopic inhibitory influences. Pain 31:359-379.
9. Cervero F, Schaible H-G, Schmidt RF (1991) Tonic descending inhibition of spinal cord neurones driven by joint afferents in normal cats and in cats with an inflamed knee joint. Exp Brain Res 83:675-678.
10. Chen L-W, Egan L, Li Z-W, Greten FR, Kagnoff MF, Karin M (2003) The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion. Nat Med 9:575-581.
11. Coggeshall RE, Hong KAP, Langford LA, Schaible H-G, Schmidt RF (1983) Discharge characteristics of fine medial articular afferents at rest and during passive movements of inflamed knee joints. Brain Res 272:185-188.
12. Danziger N, Weil-Fugazza J, LeBars D, Bouhassira D (1999) Alteration of descending modulation of nociception during the course of monoarthritis in the rat. J Neurosci 19:2394-2400.
13. Danziger N, Weil-Fugazza J, LeBars D, Bouhassira D (2001) Stage-dependent changes in the modulation of nociceptive neuronal activity during the course of inflammation. Eur J Neurosci 13:230-240.
14. Dougherty PM, Sluka KA, Sorkin LS, Westlund KN, Willis WD (1992) Neural changes in the acute arthritis in monkeys. I. Parallel enhancement of responses of spinothalamic tract neurons to mechanical stimulation and excitatory amino acids. Brain Res Rev 17:1-13.
15. Ebersberger A, Buchmann M, Ritzeler O, Michaelis M, Schaible H-G (2006) The role of spinal nuclear factor-κB in spinal hyperexcitability. NeuroReport 17:1615-1618.
16. Ebersberger A, Charbel Issa P, Vanegas H, Schaible H-G (2000) Differential effects of CGRP and CGRP8-37 upon responses to NMDA and AMPA in spinal nociceptive neurons with knee input in the rat. Neuroscience 99:171-178.
17. Ebersberger A, Grubb BD, Willingale HL, Gardiner NJ, Nebe J, Schaible H-G (1999) The intraspinal release of prostaglandin E2 in a model of acute arthritis is accompanied by an upregulation of cyclooxygenase-2 in the rat spinal cord. Neuroscience 93:775-781.
18. Ferrell WR, Wood L, Baxendale RH (1998) The effect of acute joint inflammation on flexion reflex excitability in the decerebrate, low spinal cat. Quart J Exp Physiol 373:353-365.
19. Fields HL, Clanton CH, Anderson SD (1977) Somatosensory properties of spinoreticular neurons in the cat. Brain Res 120:49-66.
20. Grigg P, Schaible H-G, Schmidt RF (1986) Mechanical sensitivity of group III and IV afferents from posterior articular nerve in normal and inflamed cat knee. J Neurophysiol 55:635-643.
21. Grill M, Heinemann A, Hoefler G, Peskar BA, Schuligoi R (2008) Effect of endotoxin treatment on the expression and localization of spinal cyclooxygenase, prostaglandin synthases, and PGD2 receptors. J Neurochem 104:1345-1357.
22. Grubb BD, Birrell J, McQueen DS, Iggo A (1991) The role of PGE2 in the sensitization of mechanoreceptors in normal and inflamed ankle joints of the rat. Exp Brain Res 84:383-392.
23. Grubb BD, Stiller RU, Schaible H-G (1993) Dynamic changes in the receptive field properties of spinal cord neurons with ankle input in rats with unilateral adjuvant-induced inflammation in the ankle region. Exp Brain Res 92:441-452.
24. Guilbaud G, Iggo A, Tegner R (1985) Sensory receptors in ankle joint capsules of normal and arthritic rats. Exp Brain Res 58:29-40.
25. He X, Proske U, Schaible H-G, Schmidt RF (1988) Acute inflammation of the knee joint in the cat alters responses of flexor motoneurones to leg movements. J Neurophysiol 59:326-340.
26. Hope PJ, Jarrott B, Schaible H-G, Clarke RW, Duggan AW (1990) Release and spread of immunoreactive neurokinin A in the cat spinal cord in a model of acute arthritis. Brain Res 533:292-299.
27. Infante C, Diaz M, Hernandez A, Constandil L, Pelissier T (2007) Expression of nitric oxide synthase isoforms in the dorsal horn of monoarthritic rats: effects of competitive and uncompetitive N-methyl-D-aspartate antagonists. Arth Res Ther 9:R53.
28. Inglis JJ, Notley CA, Essex D, Wilson AW, Feldmann M, Anand P, Williams R (2007) Collagen-induced arthritis as a model of hyperalgesia. Functional and cellular analysis of the analgesic actions of tumor necrosis factor blockade. Arthritis Rheum 56:4015-4023.
29. Jenkins DW, Feniuk W, Humphrey PP (2001) Characterization of the prostanoid receptor types involved in mediating calcitonin gene-related peptide release from cultured rat trigeminal neurones. Br J Pharmacol 134:1296-1302.
30. Kellgren JH (1939) Some painful joint condition and their relation to osteoarthritis. Clin Sci 4:193-205.
31. Kellgren JH, Samuel EP (1950) The sensitivity and innervation of the articular capsule. J Bone Joint Surg 32-B: 84-91.
32. LeBars D, Villanueva L (1998) Electrophysiological evidence for the activation of descending inhibitory controls by nociceptive afferent pathways. In: HL Fields, J-M Besson (Eds) Progress in Brain Research, vol. 77. Elsevier, Amsterdam, pp. 275-299.
33. Lee KM, Kang BS, Lee HL, Son SJ, Hwang SH, Kim DS, Park J-S, Cho H-J (2004) Spinal NF-κB activation induces COX-2 upregulation and contributes to inflammatory pain hypersensitivity. Eur J Neurosci 19:3375-3381.
34. Lewis T (1938) Suggestions relating to the study of somatic pain. Br Med J 1:321-325.
35. Lewis T (1942) Pain. MacMillan, London.
36. Liang X, Wu L, Hand T, Andreasson K (2005) Prostaglandin D2 mediates neuronal protection via the DP1 receptor. J Neurochem 92:477-486.
37. Martindale JC, Wilson AW Reeve AJ, Chessell IP, Headley PM (2007) Chronic secondary hypersensitivity of dorsal horn neurones following inflammation of the knee joint. Pain 133:79-86.
38. Menetrey D, Besson J-M (1982) Electrophysiological characteristics of dorsal horn cells in rats with cutaneous inflammation resulting from chronic arthritis. Pain 13:343-364.
39. Menetrey D, Gannon A, Levine JD, Basbaum AI (1989) Expression of c-fos protein in interneurons and projection neurons of the rat spinal cord in response to noxious somatic, articular, and visceral stimulation. J Comp Neurol 285:177-195.
40. Mense S (1997) Pathophysiologic basis of muscle pain syndromes. Myofasc Pain - Update in diagnosis and treatment. Phys Med Rehabil Clin N Am 8:23-53.
41. Meyers DER, Snow PJ (1982) The responses to somatic stimuli of deep spinothalamic tract cells in the lumbar spinal cord of the cat. J Physiol 329:355-371.
42. Minami T, Okuda-Ashitaka E, Nishizawa M, Mori H, Ito S (1997) Inhibition of nociceptininduced allodynia in conscious mice by prostaglandin D2. Br J Pharmacol 122:605-610.
43. Nakae K, Hayashi F, Hayashi M, Yamamoto N, Iino T, Yoshikawa S, Gupta J (2005) Functional role of prostacyclin receptor in rat dorsal root ganglion neurons. Neurosci Lett 388:132-137.
44. Neugebauer V, Lucke T, Grubb BD, Schaible H-G (1994a) The involvement of N-methyl-D-aspartate (NMDA) and non-NMDA receptors in the responsiveness of rat spinal neurons with input from the chronically inflamed ankle. Neurosci Lett 170:237-240.
45. Neugebauer V, Lucke T, Schaible H-G (1993) N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurones during development of acute arthritis in rat's knee joint. J Neurophysiol 70:1365-1377.
46. Neugebauer V, Lucke T, Schaible H-G (1994b) Requirement of metabotropic glutamate receptors for the generation of inflammation-evoked hyperexcitability in rat spinal cord neurons. Eur J Neurosci 6:1179-1186.
47. Neugebauer V, Rumenapp P, Schaible H-G (1996a) The role of spinal neurokinin-2 receptors in the processing of nociceptive information from the joint and in the generation and maintenance of inflammation-evoked hyperexcitability of dorsal horn neurons in the rat. Eur J Neurosci 8:249-260.
48. Neugebauer V, Rumenapp P, Schaible H-G (1996b) Calcitonin gene-related peptide isinvolved in the generation and maintenance of hyperexcitability of dorsal horn neurons observed during development of acute inflammation in rat's knee joint. Neuroscience 71:1095-1109.
49. Neugebauer V, Schaible H-G (1990) Evidence for a central component in the sensitization of spinal neurons with joint input during development of acute arthritis in cat's knee. J Neurophysiol 64:299-311.
50. Neugebauer V, Weiretter F, Schaible H-G (1995) The involvement of substance P and neurokinin-1 receptors in the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint. J Neurophysiol 73:1574-1583.
51. Rudomin P, Hernandez E (2008) Changes in synaptic effectiveness of myelinated joint afferents during capsaicin-induced inflammation of the footpad in the anaesthetized cat. Exp Brain Res 187:71-84.
52. Schaible H-G (2006a) Basic mechanisms of deep somatic pain. In: McMahon SB, Koltzenburg M (Eds) Wall and Melzack's Textbook of Pain, 5th edn. Elsevier, Churchill, Livingston, pp. 621-633.
53. Schaible H-G (2006b) Peripheral and central mechanisms of pain generation. In: Stein C (Ed) Handbook of Experimental Pharmacalogy, vol. 177. Springer-Verlag, Berlin, Heidelberg, pp. 4-28.
54. Schaible H-G, Freudenberger U, Neugebauer V, Stiller U (1994) Intraspinal release of immunoreactive calcitonin gene-related peptide during development of inflammation in the joint in vivo - a study with antibody microprobes in cat and rat. Neuroscience 62:1293-1305.
55. Schaible H-G, Grubb BD (1993) Afferent and spinal mechanisms of joint pain. Pain 55:5-54.
56. Schaible H-G, Jarrott B, Hope PJ, Duggan AW (1990) Release of immunoreactive substance P in the cat spinal cord during development of acute arthritis in cat's knee: A study with antibody bearing microprobes. Brain Res 529:214-223.
57. Schaible H-G, Neugebauer V, Cervero F, Schmidt RF (1991) Changes in tonic descending inhibition of spinal neurons with articular input during the development of acute arthritis in the cat. J Neurophysiol 66:1021-1032.
58. Schaible H-G, Schmidt RF (1985) Effects of an experimental arthritis on the sensory properties of fine articular afferent units. J Neurophysiol 54:1109-1122.
59. Schaible H-G, Schmidt RF (1988) Time course of mechanosensitivity changes in articular afferents during a developing experimental arthritis. J Neurophysiol 60:2180-2195.
60. Schaible H-G, Schmidt RF, Willis WD (1987) Enhancement of the responses of ascending tract cells in the cat spinal cord by acute inflammation of the knee joint. Exp Brain Res 66:489-499.
61. Segond von Banchet G, Petrow PK, Brauer R, Schaible H-G (2000) Monoarticular antigeninduced arthritis leads to pronounced bilateral upregulation of the expression of neurokinin 1 and bradykinin 2 receptors in dorsal root ganglion neurones of rats. Arthritis Res 2:424-427.
62. Sharif Naeini R, Cahill CM, Ribeiro-da-Silva A, Menard HA, Henry JL (2005) Remodelling of spinal nociceptive mechanisms in an animal model of monoarthritis. Eur J Neurosci 22:2005-2015.
63. Sluka KA (2002) Stimulation of deep somatic tissue with capsaicin produces long-lasting mechanical allodynia and heat hypoalgesia that depends on early activation of the cAMP pathway. J Neurosci 22:5687-5693.
64. Sluka KA, Westlund K (1992) An experimental arthritis in rats: dorsal horn aspartate and glutamate increases. Neurosci Lett 145:141-144.
65. Sorkin LS, Westlund KN, Sluka KA, Dougherty PH, Willis WD (1992) Neural changes in acute arthritis in monkeys. IV: time course of amino acid release into the lumbar dorsal horn. Brain Res Rev 17:39-50.
66. Sun S, Cao H, Han M, Li TT, Pan HL, Zhao ZQ, Zhang YQ (2007) New evidence for the involvement of spinal fraktalkine receptor in pain facilitation and spinal glial activation in rat model of monoarthritis. Pain 129:64-75.
67. Tegeder I, Niederberger E, Schmidt R, Kunz S, Guhring H, Ritzeler O, Michaelis M, Geisslinger G (2004) Specific inhibition of IκB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in rats. J Neurosci 24:1637-1645.
68. Telleria-Diaz A, Ebersberger A, Vasquez E, Schache F, Kahlenbach J, Schaible H-G (2008) Different effects of spinally applied prostaglandin D2 (PGD2) on responses of dorsal horn neurons with knee input in normal rats and in rats with acute knee inflammation. Neuroscience 156:184-192.
69. Vanegas H, Schaible H-G (2001) Prostaglandins and cyclooxygenases in the spinal cord. Prog Neurobiol 64:327-363.
70. Vasquez E, Bar K-J, Ebersberger A, Klein B, Vanegas H, Schaible H-G (2001) Spinal prostaglandins are involved in the development but not the maintenance of inflammationinduced spinal hyperexcitability. J Neurosci 21:9001-9008.
71. Willingale HL, Gardiner NJ, McLymont N, Giblett S, Grubb BD (1997) Prostanoids synthesized by cyclo-oxygenase isoforms in rat spinal cord and their contribution to the development of neuronal hyperexcitability. Br J Pharmacol 122:1593-1604.
72. Woolf CJ, Wall PD (1986) Relative effectiveness of C primary afferent fibres of different origins in evoking a prolonged facilitation of the flexor reflex in the rat. J Neurosci 6:1433-1442.
73. Yang LC, Marsala M, Yaksh TL (1996) Characterization of time course of spinal amino acids, citrulline and PGE2 release after carrageenan/kaolin-induced knee inflammation: a chronic microdialysis study. Pain 67:345-354.
74. Yu X-M, Mense S (1990) Response properties and descending control of rat dorsal horn neurons with deep receptive fields. Neuroscience 39:823-831.