메뉴 건너뛰기




Volumn 84, Issue 5, 2011, Pages 976-985

ATP synthesis, mitochondrial function, and steroid biosynthesis in rodent primary and tumor leydig cells

Author keywords

ATP; Glycolysis; Leydig cells; Mitochondria; Respiration; Steroid hormones steroid hormone receptors; Testosterone

Indexed keywords

ADENOSINE TRIPHOSPHATE; LUTEINIZING HORMONE; OLIGOMYCIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STEROID;

EID: 79956261619     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.110.087460     Document Type: Article
Times cited : (73)

References (39)
  • 1
    • 33751331631 scopus 로고    scopus 로고
    • A functional transmembrane complex: the luteinizing hormone receptor with bound ligand and G protein
    • Puett D, Li Y, DeMars G, Angelova K, Fanelli F. A functional transmembrane complex: the luteinizing hormone receptor with bound ligand and G protein. Mol Cell Endocrinol 2007; 260-262:126-136.
    • (2007) Mol Cell Endocrinol , vol.260-262 , pp. 126-136
    • Puett, D.1    Li, Y.2    DeMars, G.3    Angelova, K.4    Fanelli, F.5
  • 2
    • 34249787877 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein (StAR), a novel mitochondrial cholesterol transporter
    • Miller WL. Steroidogenic acute regulatory protein (StAR), a novel mitochondrial cholesterol transporter. Biochim Biophys Acta 2007; 1771: 663-676.
    • (2007) Biochim Biophys Acta , vol.1771 , pp. 663-676
    • Miller, W.L.1
  • 4
    • 67649288976 scopus 로고    scopus 로고
    • Cholesterol transport in steroid biosynthesis: role of protein-protein interactions and implications in disease states
    • Rone MB, Fan J, Papadopoulos V. Cholesterol transport in steroid biosynthesis: role of protein-protein interactions and implications in disease states. Biochim Biophys Acta 2009; 1791:646-658.
    • (2009) Biochim Biophys Acta , vol.1791 , pp. 646-658
    • Rone, M.B.1    Fan, J.2    Papadopoulos, V.3
  • 5
    • 33845977384 scopus 로고    scopus 로고
    • Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis
    • Liu J, Rone MB, Papadopoulos V. Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis. J Biol Chem 2006; 281:38879-38893.
    • (2006) J Biol Chem , vol.281 , pp. 38879-38893
    • Liu, J.1    Rone, M.B.2    Papadopoulos, V.3
  • 6
    • 10644266103 scopus 로고    scopus 로고
    • Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones
    • Payne AH, Hales DB. Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocr Rev 2004; 25:947-970.
    • (2004) Endocr Rev , vol.25 , pp. 947-970
    • Payne, A.H.1    Hales, D.B.2
  • 7
    • 76749091531 scopus 로고    scopus 로고
    • New extension of the Mitchell Theory for oxidative phosphorylation in mitochondria of living organisms
    • Kadenbach B, Ramzan R, Wen L, Vogt S. New extension of the Mitchell Theory for oxidative phosphorylation in mitochondria of living organisms. Biochim Biophys Acta 2010; 1800:205-212.
    • (2010) Biochim Biophys Acta , vol.1800 , pp. 205-212
    • Kadenbach, B.1    Ramzan, R.2    Wen, L.3    Vogt, S.4
  • 8
    • 67349200007 scopus 로고    scopus 로고
    • Supramolecular organization of ATP synthase and respiratory chain in mitochondrial membranes
    • Wittig I, Schägger H. Supramolecular organization of ATP synthase and respiratory chain in mitochondrial membranes. Biochim Biophys Acta 2009; 1787:672-680.
    • (2009) Biochim Biophys Acta , vol.1787 , pp. 672-680
    • Wittig, I.1    Schägger, H.2
  • 9
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg Effect: the metabolic requirements of cell proliferation
    • Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg Effect: the metabolic requirements of cell proliferation. Science 2009; 324:1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 10
    • 54049121836 scopus 로고    scopus 로고
    • Comparison of glycolysis and oxidative phosphorylation as energy sources for mammalian sperm motility, using the combination of fluorescence imaging, laser tweezers, and real-time automated tracking and trapping
    • Nascimento JM, Shi LZ, Tam J, Chandsawangbhuwana C, Durrant B, Botvinick EL, Berns MW. Comparison of glycolysis and oxidative phosphorylation as energy sources for mammalian sperm motility, using the combination of fluorescence imaging, laser tweezers, and real-time automated tracking and trapping. J Cell Physiol 2008; 217:745-751.
    • (2008) J Cell Physiol , vol.217 , pp. 745-751
    • Nascimento, J.M.1    Shi, L.Z.2    Tam, J.3    Chandsawangbhuwana, C.4    Durrant, B.5    Botvinick, E.L.6    Berns, M.W.7
  • 11
    • 67349202746 scopus 로고    scopus 로고
    • 1H NMR to investigate metabolism and energy supply in rhesus macaque sperm
    • Lin CY, Hung PH, VandeVoort CA, Miller MG. 1H NMR to investigate metabolism and energy supply in rhesus macaque sperm. Reprod Toxicol 2009; 28:75-80.
    • (2009) Reprod Toxicol , vol.28 , pp. 75-80
    • Lin, C.Y.1    Hung, P.H.2    VandeVoort, C.A.3    Miller, M.G.4
  • 12
    • 33746084479 scopus 로고    scopus 로고
    • Energized, polarized, and actively respiring mitochondria are required for acute Leydig cell steroidogenesis
    • Allen JA, Shankara T, Janus P, Buck S, Diemer T, Hales KH, Hales DB. Energized, polarized, and actively respiring mitochondria are required for acute Leydig cell steroidogenesis. Endocrinology 2006; 147:3924-3935.
    • (2006) Endocrinology , vol.147 , pp. 3924-3935
    • Allen, J.A.1    Shankara, T.2    Janus, P.3    Buck, S.4    Diemer, T.5    Hales, K.H.6    Hales, D.B.7
  • 13
    • 34250859711 scopus 로고    scopus 로고
    • Effect of myxothiazol on Leydig cell steroidogenesis: inhibition of luteinizing hormone-mediated testosterone synthesis but stimulation of basal steroidogenesis
    • Midzak AS, Liu J, Zirkin BR, Chen H. Effect of myxothiazol on Leydig cell steroidogenesis: inhibition of luteinizing hormone-mediated testosterone synthesis but stimulation of basal steroidogenesis. Endocrinology 2007; 148:2583-2590.
    • (2007) Endocrinology , vol.148 , pp. 2583-2590
    • Midzak, A.S.1    Liu, J.2    Zirkin, B.R.3    Chen, H.4
  • 14
    • 0032977317 scopus 로고    scopus 로고
    • Effects of disruption of the mitochondrial electrochemical gradient on steroidogenesis and the steroidogenic acute regulatory (StAR) protein
    • King SR, Liu Z, Soh J, Eimerl S, Orly J, Stocco DM. Effects of disruption of the mitochondrial electrochemical gradient on steroidogenesis and the steroidogenic acute regulatory (StAR) protein. J Steroid Biochem Mol Biol 1999; 69:143-154.
    • (1999) J Steroid Biochem Mol Biol , vol.69 , pp. 143-154
    • King, S.R.1    Liu, Z.2    Soh, J.3    Eimerl, S.4    Orly, J.5    Stocco, D.M.6
  • 15
    • 34547679741 scopus 로고    scopus 로고
    • An arachidonic acid generation/export system involved in the regulation of cholesterol transport in mitochondria of steroidogenic cells
    • Duarte A, Castillo AF, Castilla R, Maloberti P, Paz C, Podestá EJ, Cornejo Maciel F. An arachidonic acid generation/export system involved in the regulation of cholesterol transport in mitochondria of steroidogenic cells. FEBS Lett 2007; 581:4023-4028.
    • (2007) FEBS Lett , vol.581 , pp. 4023-4028
    • Duarte, A.1    Castillo, A.F.2    Castilla, R.3    Maloberti, P.4    Paz, C.5    Podestá, E.J.6    Cornejo Maciel, F.7
  • 17
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. On the origin of cancer cells. Science 1956; 123:309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 18
    • 0023222052 scopus 로고
    • Effect of luteinizing hormone deprivation in situ on steroidogenesis of rat Leydig cells purified by a multistep procedure
    • Klinefelter GR, Hall PF, Ewing LL. Effect of luteinizing hormone deprivation in situ on steroidogenesis of rat Leydig cells purified by a multistep procedure. Biol Reprod 1987; 36:769-783.
    • (1987) Biol Reprod , vol.36 , pp. 769-783
    • Klinefelter, G.R.1    Hall, P.F.2    Ewing, L.L.3
  • 19
    • 0018870772 scopus 로고
    • Luteinizing hormone receptors and testosterone synthesis in two distinct populations of Leydig cells
    • Payne AH, Downing JR, Wong KL. Luteinizing hormone receptors and testosterone synthesis in two distinct populations of Leydig cells. Endocrinology 1980; 106:1424-1429.
    • (1980) Endocrinology , vol.106 , pp. 1424-1429
    • Payne, A.H.1    Downing, J.R.2    Wong, K.L.3
  • 20
    • 0019364734 scopus 로고
    • Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptors and steroidogenic responses
    • Ascoli M. Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptors and steroidogenic responses. Endocrinology 1981; 108:88-95.
    • (1981) Endocrinology , vol.108 , pp. 88-95
    • Ascoli, M.1
  • 21
    • 0242582202 scopus 로고    scopus 로고
    • Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes
    • Aon MA, Cortassa S, Marbán E, O'Rourke B. Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes. J Biol Chem 2003; 278: 44735-44744.
    • (2003) J Biol Chem , vol.278 , pp. 44735-44744
    • Aon, M.A.1    Cortassa, S.2    Marbán, E.3    O'Rourke, B.4
  • 22
    • 0036670612 scopus 로고    scopus 로고
    • Development of a high-throughput screening assay for mitochondrial membrane potential in living cells
    • Huang SG. Development of a high-throughput screening assay for mitochondrial membrane potential in living cells. J Biomol Screen 2002; 7:383-389.
    • (2002) J Biomol Screen , vol.7 , pp. 383-389
    • Huang, S.G.1
  • 23
    • 0042433242 scopus 로고    scopus 로고
    • 2 production by membrane potential and NAD(P)H redox state
    • 2 production by membrane potential and NAD(P)H redox state. J Neurochem 2003; 86:1101-1107.
    • (2003) J Neurochem , vol.86 , pp. 1101-1107
    • Starkov, A.A.1    Fiskum, G.2
  • 24
    • 23044456402 scopus 로고    scopus 로고
    • 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro
    • Zhu Z, Jiang W, McGinley JN, Thompson HJ. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res 2005; 65:7023-7030.
    • (2005) Cancer Res , vol.65 , pp. 7023-7030
    • Zhu, Z.1    Jiang, W.2    McGinley, J.N.3    Thompson, H.J.4
  • 25
    • 0031470335 scopus 로고    scopus 로고
    • Import of lipids into mitochondria
    • Daum G, Vance JE. Import of lipids into mitochondria. Prog Lipid Res 1997; 36:103-130.
    • (1997) Prog Lipid Res , vol.36 , pp. 103-130
    • Daum, G.1    Vance, J.E.2
  • 26
    • 46349104634 scopus 로고    scopus 로고
    • Energetics of protein translocation into mitochondria
    • Mokranjac D, Neupert W. Energetics of protein translocation into mitochondria. Biochim Biophys Acta 2008; 1777:758-762.
    • (2008) Biochim Biophys Acta , vol.1777 , pp. 758-762
    • Mokranjac, D.1    Neupert, W.2
  • 27
    • 0035824668 scopus 로고    scopus 로고
    • Mitochondrial processing of newly synthesized steroidogenic acute regulatory protein (StAR), but not total StAR, mediates cholesterol transfer to cytochrome P450 side chain cleavage enzyme in adrenal cells
    • Artemenko IP, Zhao D, Hales DB, Hales KH, Jefcoate CR. Mitochondrial processing of newly synthesized steroidogenic acute regulatory protein (StAR), but not total StAR, mediates cholesterol transfer to cytochrome P450 side chain cleavage enzyme in adrenal cells. J Biol Chem 2001; 276: 46583-46596.
    • (2001) J Biol Chem , vol.276 , pp. 46583-46596
    • Artemenko, I.P.1    Zhao, D.2    Hales, D.B.3    Hales, K.H.4    Jefcoate, C.R.5
  • 28
    • 0030472793 scopus 로고    scopus 로고
    • ATP and a mitochondrial electrochemical gradient are required for functional activity of the steroidogenic acute regulatory (StAR) protein in isolated mitochondria
    • King SR, Stocco DM. ATP and a mitochondrial electrochemical gradient are required for functional activity of the steroidogenic acute regulatory (StAR) protein in isolated mitochondria. Endocr Res 1996; 22:505-514.
    • (1996) Endocr Res , vol.22 , pp. 505-514
    • King, S.R.1    Stocco, D.M.2
  • 29
    • 0029115566 scopus 로고
    • Import of sterols into mitochondria of the yeast Saccharomyces cerevisiae
    • Tuller G, Daum G. Import of sterols into mitochondria of the yeast Saccharomyces cerevisiae. FEBS Lett 1995; 372:29-32.
    • (1995) FEBS Lett , vol.372 , pp. 29-32
    • Tuller, G.1    Daum, G.2
  • 30
    • 0038053885 scopus 로고    scopus 로고
    • ATP synthesis driven by proton transport in F1F0-ATP synthase
    • Weber J, Senior AE. ATP synthesis driven by proton transport in F1F0-ATP synthase. FEBS Lett 2003; 545:61-70.
    • (2003) FEBS Lett , vol.545 , pp. 61-70
    • Weber, J.1    Senior, A.E.2
  • 32
    • 73249137166 scopus 로고    scopus 로고
    • Mitochondrial complex I decrease is responsible for bioenergetic dysfunction in K-ras transformed cells
    • Baracca A, Chiaradonna F, Sgarbi G, Solaini G, Alberghina L, Lenaz G. Mitochondrial complex I decrease is responsible for bioenergetic dysfunction in K-ras transformed cells. Biochim Biophys Acta 2010; 1797:314-323.
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 314-323
    • Baracca, A.1    Chiaradonna, F.2    Sgarbi, G.3    Solaini, G.4    Alberghina, L.5    Lenaz, G.6
  • 33
    • 0032490090 scopus 로고    scopus 로고
    • Complex I inhibitors as insecticides and acaricides
    • Lümmen P. Complex I inhibitors as insecticides and acaricides. Biochim Biophys Acta 1998; 1364:287-296.
    • (1998) Biochim Biophys Acta , vol.1364 , pp. 287-296
    • Lümmen, P.1
  • 34
    • 69549084529 scopus 로고    scopus 로고
    • Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?
    • Cicchetti F, Drouin-Ouellet J, Gross RE. Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models? Trends Pharmacol Sci 2009, 30:475-483.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 475-483
    • Cicchetti, F.1    Drouin-Ouellet, J.2    Gross, R.E.3
  • 35
    • 9744274529 scopus 로고    scopus 로고
    • Mitochondrial complex I inhibition depletes plasma testosterone in the rotenone model of Parkinson's disease
    • Alam M, Schmidt WJ. Mitochondrial complex I inhibition depletes plasma testosterone in the rotenone model of Parkinson's disease. Physiol Behav 2004; 83:395-400.
    • (2004) Physiol Behav , vol.83 , pp. 395-400
    • Alam, M.1    Schmidt, W.J.2
  • 36
    • 0030989604 scopus 로고    scopus 로고
    • Essential role of adenosine triphosphate in activation of 17beta-hydroxysteroid dehydrogenase in rat Leydig cells
    • Khanum A, Buczko E, Dufau ML. Essential role of adenosine triphosphate in activation of 17beta-hydroxysteroid dehydrogenase in rat Leydig cells. Endocrinology 1997; 138:1612-1620.
    • (1997) Endocrinology , vol.138 , pp. 1612-1620
    • Khanum, A.1    Buczko, E.2    Dufau, M.L.3
  • 38
    • 22544470581 scopus 로고    scopus 로고
    • Involvement of protein kinase C and cyclic adenosine 30, 50-monophosphate-dependent kinase in steroidogenic acute regulatory protein expression and steroid biosynthesis in Leydig cells
    • Jo Y, King SR, Khan SA, Stocco DM. Involvement of protein kinase C and cyclic adenosine 30,50-monophosphate-dependent kinase in steroidogenic acute regulatory protein expression and steroid biosynthesis in Leydig cells. Biol Reprod 2005; 73:244-255.
    • (2005) Biol Reprod , vol.73 , pp. 244-255
    • Jo, Y.1    King, S.R.2    Khan, S.A.3    Stocco, D.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.