Trefoil factor family peptide 2 acts pro-proliferative and pro-apoptotic in the murine retina

Histochemistry and Cell Biology

Volumn 135, Issue 5, 2011, Pages 461-473

  Paunel Görgülü, Adnana N ^a,c   Franke, Andreas G ^a,d   Paulsen, Friedrich P ^b   Dünker, Nicole ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Apoptosis; Cell death; Spasmolytic polypeptide; TFF peptide; Trefoil factors

Indexed keywords

CASPASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAX; PROTEIN BCL 2; STAT3 PROTEIN; TREFOIL PEPTIDE; TREFOIL PEPTIDE 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RETINA; RETINA BIPOLAR GANGLION CELL; RETINA DEVELOPMENT; RETINA GANGLION CELL; RETINA NERVE CELL;

ANIMALS; APOPTOSIS; CASPASES; CELL PROLIFERATION; CELLS, CULTURED; FEMALE; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MUCINS; MUSCLE PROTEINS; PEPTIDES; PREGNANCY; RECOMBINANT PROTEINS; RETINA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

LOTUS; MURINAE;

EID: 79956224688     PISSN: 09486143     EISSN: 1432119X     Source Type: Journal    
DOI: 10.1007/s00418-011-0810-6     Document Type: Article

References (50)

1. Baus-Loncar M, Giraud AS (2005) Multiple regulatory pathways for trefoil factor (TFF) genes. Cell Mol Life Sci 62:2921-2931 (Pubitemid 43004745)
2. Beier M, Franke A, Paunel-Görgülü AN, Scheerer N, Dünker N (2006) Transforming growth factor beta mediates apoptosis during all postnatal programmed cell death periods of the developing murine retina. Neurosci Res 56:193-203 (Pubitemid 44374792)
3. Bossenmeyer-Pourie C, Kannan R, Ribieras S, Wendling C, Stoll I, Thim L, Tomasetto C, Rio MC (2002) The trefoil factor 1 participates in gastrointestinal cell differentiation by delaying G1-S phase transition and reducing apoptosis. J Cell Biol 157:761-770 (Pubitemid 34847814)
4. Chalasani SH, Baribaud F, Coughlan CM, Sunshine MJ, Lee VM, Doms RW, Littman DR, Raper JA (2003) The chemokine stromal cell-derived factor-1 promotes the survival of embryonic retinal ganglion cells. J Neurosci 23:4601-4612 (Pubitemid 36706190)
5. Chwieralski CE, Schnurra I, Thim L, Hoffmann W (2004) Epidermal growth factor and trefoil factor family 2 synergistically trigger chemotaxis on BEAS-2B cells via different signaling cascades. Am J Respir Cell Mol Biol 31:528-537 (Pubitemid 39463401)
6. Dignass A, Lynch-Devaney K, Kindon H, Thim L, Podolsky DK (1994) Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway. J Clin Invest 94:376-383 (Pubitemid 24218114)
7. Dubeykovskaya Z, Dubeykovskaya A, Solal-Cohen J, Wang TC (2009) Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines. J Biol Chem 284:3650-3662
8. Dünker N, Valenciano AI, Franke A, Hernandez-Sanchez C, Dressel R, Behrendt M, de Pablo F, Krieglstein K, De la Rosa EJ (2005) Balance of pro-apoptotic transforming growth factor-beta and anti-apoptotic insulin effects in the control of cell death in the postnatal mouse retina. Eur J Neurosci 22:28-38 (Pubitemid 41059969)
9. Efstathiou JA, Noda M, Rowan A, Dixon C, Chinery R, Jawhari A, Hattori T, Wright NA, Bodmer WF, Pignatelli M (1998) Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. Proc Natl Acad Sci USA 95:3122-3127 (Pubitemid 28135865)
10. Emami S, Le Flock N, Bruyneel L, Thim L, Ma F, Westley B, Rio MC, Mareel M, Gespach C (2001) Induction of scattering and cellular invasion by trefoil peptides in src- and RhoA-transformed kidney and colonic epithelial cells. FASEB J 15:351-361 (Pubitemid 32141427)
11. Emami S, Rodrigues S, Rodrigue CM (2004) Trefoil factor family (TFF) peptides and cancer progression. Peptides 25:885-898 (Pubitemid 38721356)
12. Farrell JJ, Taupin D, Koh TJ, Chen D, Zhao CM, Podolsky DK, Wang TC (2002) TFF2/SP-deficient mice show decreased gastric proliferation, increased acid secretion, and increased susceptibility to NSAID injury. J Clin Invest 109:193-204 (Pubitemid 34083739)
13. Franke AG, Gubbe C, Beier M, Dünker N (2006) Transforming growth factors beta and bone morphogenetic proteins: cooperative players in chick and murine programmed retinal cell death. J Comp Neurol 495:263-278 (Pubitemid 43271472)
14. Göke MN, Cook JR, Kunert KS, Fini ME, Gipson IK, Podolsky DK (2001) Trefoil peptides promote restitution of wounded corneal epithelial cells. Exp Cell Res 264:337-344 (Pubitemid 32980238)
15. Graness A, Chwieralski CE, Reinhold D, Thim L, Hoffmann W (2002) Protein kinase C and ERK activation are required for TFF peptide-stimulated bronchial epithelial cell migration and tumor necrosis factor-a-induced interleukin-6n (IL-6) and IL-8 secretion. J Biol Chem 277:18440-18446 (Pubitemid 34952390)
16. Hasegawa T, McLeod DS, Prow T, Merges C, Grebe R, Lutty GA (2008) Vascular precursors in developing human retina. Invest Ophthalmol Vis Sci 49:2178-2192
17. Hinz M, Schwegler H, Chwieralski CE, Laube G, Linke R, Pohle W, Hoffmann W (2004) Trefoil factor family (TFF) expression in the mouse brain and pituitary: changes in the developing cerebellum. Peptides 25:827-832 (Pubitemid 38721349)
18. Hirota M, Awatsuji H, Sugihara Y, Miyashita S, Furukawa Y, Hayashi K (1995) Expression of pS2 gene in rat brain. Biochem Mol Biol Int 5:1079-1084 (Pubitemid 26176407)
19. Hoffmann W (2009) Trefoil factor family (TFF) peptides and chemokine receptors: a promising relationship. J Med Chem 52:6505-6510
20. Hoffmann W, Hauser F (1993) The P-domain or trefoil motif: a role in renewal and pathology of mucous epithelia? Trends Biochem Sci 18:239-243
21. Hoffmann W, Jagla W (2002) Cell type specific expression of secretory TFF peptides: colocalization with mucins and synthesis in the brain. Int Rev Cytol 213:147-181 (Pubitemid 34112918)
22. Hoffmann W, Jagla W, Wiede A (2001) Molecular medicine of TFF-peptides: from gut to brain. Histol Histopathol 16:319-334 (Pubitemid 32094047)
23. Hoosein NM, Thim L, Jorgensen KH, Brattain MG (1989) Growth stimulatory effect of pancreatic spasmolytic polypeptide on cultured colon and breast tumor cells. FEBS 247:303-306 (Pubitemid 19129268)
24. Kanai M, Mullen C, Podolsky DK (1998) Intestinal trefoil factor induces inactivation of extracellular signal-regulated protein kinase in intestinal epithelial cells. Proc Natl Acad Sci USA 95:178-182
25. Kinoshita T, Taupin DR, Itoh H, Podolsky DK (2000) Distinct pathways of cell migration and antiapoptotic response to epithelial injury: structure-function analysis of human intestinal trefoil factor. Mol Cell Biol 20:4680-4690 (Pubitemid 30396115)
26. Lalani EN, Williams R, Jayaram Y, Gilbert C, Chaudhary KS, Siu LS, Koumarianou A, Playford R, Stamp GW (1999) Trefoil factor-2, human spasmolytic polypeptide, promotes branching morphogenesis in MCF-7 cells. Lab Invest 79:537-546 (Pubitemid 29228212)
27. Langer G, Jagla W, Behrens-Baumann W, Walter S, Hoffmann W (1999) Secretory peptides TFF1 and TFF3 synthesized in human conjunctival goblet cells. Inv Opthalmol Vis Sci 40:2220-2224 (Pubitemid 29418375)
28. Lima e Silva R, Shen J, Hackett SF, Kachi S, Akiyama H, Kiuchi K, Yokoi K, Hatara MC, Lauer T, Aslam S, Gong YY, Xiao WH, Khu NH, Thut C, Campochiaro PA (2007) The SDF-1/CXCR4 ligand/receptor pair is an important contributor to several types of ocular neovascularization. FASEB J 21:3219-3230
29. May FEB, Semple JI, Newton JL, Westley BR (2000) The human two domain trefoil protein, TFF2, is glycosylated in vivo in the stomach. Gut 46:454-459 (Pubitemid 30305806)
30. Oertel M, Graness A, Thim L, Buhling F, Kalbacher H, Hoffmann W (2001) Trefoil factor family-peptides promote migration of human bronchial epithelial cells: synergistic effect with epidermal growth factor. Am J Respir Cell Mol Biol 25:418-424 (Pubitemid 33037673)
31. Otto WR, Patel K, McKinnell I, Evans MD, Le CY, Frith D, Hanrathan S, Blight K, Blin N, Kayademir T, Poulson R, Jeffery R, Hunt T, Wrigth NA, McGregor F, Oien KA (2006) Identification of blottin: a novel gastric trefoil factor family-2 binding protein. Proteomics 6:4235-4245 (Pubitemid 44277027)
32. Paulsen FP, Berry MS (2006) Mucins and TFF peptides of the tear film and lacrimal apparatus. Prog Histochem Cytochem 41:1-56
33. Paulsen FP, Hinz M, Schaudig U, Thale AB, Hoffmann W (2002) TFF peptides in the human efferent tear ducts. Invest Ophthalmol Vis Sci 43:3359-3364 (Pubitemid 35334340)
34. Paulsen FP, Schaudig U, Fabian A, Ehrich D, Sel S (2006) TFF peptides and mucins are major components of dacryoliths. Graefe's Arch Clin Exp Ophthalmol 244:1160-1170 (Pubitemid 44269595)
35. Paulsen FP, Woon CW, Varoga D, Jansen A, Garreis F, Jäger K, Amm M, Podolsky DK, Steven P, Barker NP, Sel S (2008) Intestinal trefoil factor/TFF3 promotes re-epithelialization of corneal wounds. J Biol Chem 238:13418-13427
36. Pequignot MO, Provost AC, Salle S, Taupin P, Sainton KM, Marchant D, Martinou JC, Ameisen JC, Jais JP, Abitbol M (2003) Major role of BAX in apoptosis during retinal development and in establishment of a functional postnatal retina. Dev Dyn 228:231-238 (Pubitemid 37193635)
37. Poulsen SS, Thulesen J, Hartmann B, Kissow HL, Nexo E, Thim L (2003) Injected TFF1 and TFF3 bind to TFF2-immunoreactive cells in the gastrointestinal tract in rats. Regul Pept 115:91-99 (Pubitemid 37289351)
38. Reymond A, Marigo V, Yaylaoglu MB, Leoni A, Ucla C, Scamuffa N, Caccioppoli C, Dermitzakis ET, Lyle R, Banfi S, Eichele G, Antonarakis SE, Ballabio A (2002) Human chromosome 21 gene expression atlas in the mouse. Nature 420:582-586 (Pubitemid 35477052)
39. Rivat C, Rodriguez S, Bruyneel E, Pietu G, Robert A, Redeuilh G, Bracke M, Gespach C, Attoub S (2005) Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor3 (TFF3) - and vascular endothelial growth factor - mediated cellular invasion and tumor growth. Cancer Res 65:195-202
40. Rösler S, Haase T, Claassen H, Schulze U, Schicht M, Riemann D, Brandt J, Wohlrab D, Müller-Hilke B, Goldring MB, Sel S, Varoga D, Garreis F, Paulsen FP (2010) Trefoil factor 3 is induced during degenerative and inflammatory joint disease activates matrix metalloproteinases and enhances apoptosis of articular cartilage chondrocytes. Arthritis Rheum 62:815-825
41. Siu LS, Romanska H, Abel PD, Baus-Loncar M, Kayademir T, Stamp GWH, Lalani EN (2004) TFF2 (trefoil family factor2) inhibits apoptosis in breast and colorectal cancer cell lines. Peptides 25:855-863 (Pubitemid 38721353)
42. Steven P, Schäfer G, Nölle B, Hinz M, Hoffmann W, Paulsen F (2004) Distribution of TFF peptides in corneal disease and pterygium. Peptides 25:819-825 (Pubitemid 38721348)
43. Taupin D, Podolsky DK (2003) Trefoil factors: initiators of mucosal healing nature reviews. Mol Cell Biol 4:721-732 (Pubitemid 37082187)
44. Taupin D, Wu DC, Jeon WK, Devaney K, Wang TC, Podolsky DK (1999) The trefoil gene family are coordinately expressed immediate-early genes: EGF receptor and MAP kinase dependent interregulation. J Clin Invest 103:R31-R38 (Pubitemid 29218307)
45. Taupin DR, Kinoshita K, Podolsky DK (2000) Intestinal trefoil factor confers colonic epithelial resistance to apoptosis. Proc Natl Acad Sci USA 97:799-804 (Pubitemid 30070390)
46. Thim L, Mortz E (2000) Isolation and characterization of putative trefoil peptide receptors. Regul Pept 90:61-68 (Pubitemid 30331011)
47. Thim L, Jorgensen KH, Jorgensen KD (1982) Pancreatic spasmolytic polypeptide (PSP):II. Radioimmunological determination of PSP in porcine tissue, plasma and pancreatic juice. Regul Pept 3:221-230
48. Tomita M, Itoh H, Ishikawa N, Higa A, Ide H, Murakumo Y, Maruyama H, Koga Y, Nawa Y (1995) Molecular cloning of mouse intestinal trefoil factor and its expression during goblet cell changes. Biochem J 311:293-297
49. Uchino H, Kataoka H, Itoh H, Hamasuna R, Koono M (2000) Overexpression of intestinal trefoil factor in human colon carcinoma cells reduces cellular growth in vitro and in vivo. Gastroenterology 118:60-69 (Pubitemid 30020373)
50. Westley BR, Griffin SM, May FE (2005) Interaction between TFF1 a gastric tumor suppressor trefoil protein and TFIZ1 a brichos domain-containing protein with homology to SP-C. Biochemistry 44:7967-7975 (Pubitemid 40776657)