Impact of a glycogen phosphorylase inhibitor and metformin on basal and glucagon-stimulated hepatic glucose flux in conscious dogs

Journal of Pharmacology and Experimental Therapeutics

Volumn 337, Issue 3, 2011, Pages 610-620

  Torres, Tracy P ^a   Sasaki, Noriyasu ^a   Donahue, E Patrick ^a   Lacy, Brooks ^a   Printz, Richard L ^a   Cherrington, Alan D ^a   Treadway, Judith L ^b   Shiota, Masakazu ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (5 CHLOROINDOLE 2 CARBONYL)AMINO 2 HYDROXY 4 PHENYLBUTYRIC ACID N METHYL N METHOXYAMIDE; ADRENALIN; CP 316819; FATTY ACID; GLUCAGON; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLUCOSE 6 PHOSPHATE; GLYCOGEN PHOSPHORYLASE; GLYCOGEN SYNTHASE; HYDROCORTISONE; METFORMIN; NORADRENALIN; PROTEIN SERINE THREONINE KINASE INHIBITOR; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCOSE;

ADRENALIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; GLUCAGON BLOOD LEVEL; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; GLYCOGEN SYNTHESIS; GLYCOGENOLYSIS; HYDROCORTISONE BLOOD LEVEL; LIVER BLOOD FLOW; LIVER METABOLISM; NONHUMAN; NORADRENALIN BLOOD LEVEL; PRIORITY JOURNAL;

ANIMALS; BLOOD GLUCOSE; DOGS; ENZYME INHIBITORS; FASTING; FATTY ACIDS, NONESTERIFIED; FEMALE; GLUCAGON; GLUCONEOGENESIS; GLUCOSE; GLUCOSE-6-PHOSPHATASE; GLYCEROL; GLYCOGEN PHOSPHORYLASE, LIVER FORM; HEMATOCRIT; HYPOGLYCEMIC AGENTS; INDOLES; INSULIN; LACTIC ACID; LIVER; LIVER GLYCOGEN; MALE; METFORMIN; PHENYLBUTYRATES;

EID: 79956212666     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.177899     Document Type: Article

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