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85031079706
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Fact Sheet No. 138. World Health Organization, Geneva, 2002
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Fact Sheet No. 138. World Health Organization, Geneva, 2002.
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85031079905
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US Patent 4,145,432, 1979
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(a) Sato, Y. US Patent 4,145,432, 1979.
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Sato, Y.1
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14
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85031080257
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US Patent 4,284,634, 1981
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(b) Sato, Y. US Patent 4,284,634, 1981.
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Sato, Y.1
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16
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85031073143
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Treatment of the concentrated diacid compound with 2 equiv NaOH(aq) precluded formation of the maleic anhydride
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Treatment of the concentrated diacid compound with 2 equiv NaOH(aq) precluded formation of the maleic anhydride.
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17
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85031079938
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note
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50 values derived from inhibiting phosphorolysis of glycogen using recombinant human liver or muscle enzyme. The standard error for this assay (15%) arose from titration of an internal standard. Glucose-1-phosphate production was monitored via an enzymatic assay involving phosphoglucomutase/glucose-6-phosphate dehydrogenase-mediated NADH production (ex. 340 nm, em. 465 nm)
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18
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85031069265
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note
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Inhibition of glucagon-stimulated glycogenolysis in primary rat hepatocytes. The standard error for this assay (15%) derived from an internal standard. Inhibition of glucose production determined by digesting remaining glycogen and quantifying by monitoring glucose dehydrogenase-mediated NADPH production (ex. 340 nm, em. 465 nm).
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19
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85031079004
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note
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+: 552.14; found: 552.1.
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20
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85031081212
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note
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Glucose levels determined at indicated times post-dosing of either compound 29 or vehicle. Each curve represents a single group of n=7 animals, and timepoints therein an average of the group.
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21
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85031079549
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note
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max=12 nM, %F=4.5.
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22
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0004155427
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W.H. Freeman and Co.: New York
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Stryer, L. Biochemistry; W.H. Freeman and Co.: New York, 1995; p 598.
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Biochemistry
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Stryer, L.1
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