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Volumn 2, Issue 4, 2010, Pages

Reversal of Endocrinopathies in Transfusional Iron Overload patients-the next frontier in Iron chelation

Author keywords

Deferasirox; Deferiprone; Desferrioxamine; Endocrine disorders; Magnetic resonance imaging; Thalassemia major

Indexed keywords

DEFERASIROX; DEFERIPRONE; DEFEROXAMINE; DEFEROXAMINE MESYLATE; IRON; REACTIVE OXYGEN METABOLITE; THYROXINE;

EID: 79956083944     PISSN: 17598958     EISSN: 17598966     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (59)
  • 1
    • 64849100325 scopus 로고    scopus 로고
    • Improving survival with deferiprone treatment in patients with thalassemia major: A prospective multicenter randomised clinical trial under the auspices of the Italian Society for Thalassemia and Hemoglobinopathies
    • 2009 May- Jun
    • Maggio A, Vitrano A, Capra M, et al. Improving survival with deferiprone treatment in patients with thalassemia major: a prospective multicenter randomised clinical trial under the auspices of the Italian Society for Thalassemia and Hemoglobinopathies. Blood Cells Mol Dis. 2009 May- Jun;42(3):247-251.
    • Blood Cells Mol Dis , vol.42 , Issue.3 , pp. 247-251
    • Maggio, A.1    Vitrano, A.2    Capra, M.3
  • 2
    • 73149099158 scopus 로고    scopus 로고
    • Improved survival in thalassemia major patients on switching from desferrioxamine to combined chelation therapy with desferrioxamine and deferiprone
    • 2009 Dec
    • Telfer PT, Warburton F, Christou S, et al. Improved survival in thalassemia major patients on switching from desferrioxamine to combined chelation therapy with desferrioxamine and deferiprone. Haematologica. 2009 Dec;94(12):1777-1778.
    • Haematologica , vol.94 , Issue.12 , pp. 1777-1778
    • Telfer, P.T.1    Warburton, F.2    Christou, S.3
  • 3
    • 3042758517 scopus 로고    scopus 로고
    • Complications of beta-thalassemia major in North America
    • 2004 Jul 1
    • Cunningham MJ, Macklin EA, Neufeld EJ, Cohen AR. Complications of beta-thalassemia major in North America. Blood. 2004 Jul 1;104(1): 34-39.
    • Blood , vol.104 , Issue.1 , pp. 34-39
    • Cunningham, M.J.1    Macklin, E.A.2    Neufeld, E.J.3    Cohen, A.R.4
  • 4
    • 20844460608 scopus 로고    scopus 로고
    • Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine
    • 2004 Oct
    • Borgna-Pignatti C, Rugolotto S, De Stefano P, et al. Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine. Haematologica. 2004 Oct;89(10):1187-1193.
    • Haematologica , vol.89 , Issue.10 , pp. 1187-1193
    • Borgna-Pignatti, C.1    Rugolotto, S.2    de Stefano, P.3
  • 5
    • 12544260252 scopus 로고    scopus 로고
    • Prevalence of endocrine complications and short stature in patients with thalassaemia major: A multicenter study by the Thalassaemia International Federation (TIF)
    • 2004 Dec
    • De Sanctis V, Eleftheriou A, Malaventura C. Prevalence of endocrine complications and short stature in patients with thalassaemia major: a multicenter study by the Thalassaemia International Federation (TIF). Pediatr Endocrinol Rev. 2004 Dec;2(Suppl. 2):249-255.
    • Pediatr Endocrinol Rev , vol.2 , Issue.SUPPL. 2 , pp. 249-255
    • de Sanctis, V.1    Eleftheriou, A.2    Malaventura, C.3
  • 6
    • 37549022198 scopus 로고    scopus 로고
    • Endocrine complications in patients with Thalassaemia Major
    • 2007 Dec
    • Toumba M, Sergis A, Kanaris C, Skordis N. Endocrine complications in patients with Thalassaemia Major. Pediatr Endocrinol Rev. 2007 Dec;5(2):642-648.
    • Pediatr Endocrinol Rev , vol.5 , Issue.2 , pp. 642-648
    • Toumba, M.1    Sergis, A.2    Kanaris, C.3    Skordis, N.4
  • 7
    • 12544259078 scopus 로고    scopus 로고
    • Diabetes mellitus and impaired glucose tolerance in thalassaemia major: Incidence, prevalence, risk factors and survival in patients followed in the Ferrara Center
    • 2004 Dec
    • Gamberini MR, Fortini M, De Sanctis V, Gilli G, Testa MR. Diabetes mellitus and impaired glucose tolerance in thalassaemia major: incidence, prevalence, risk factors and survival in patients followed in the Ferrara Center. Pediatr Endocrinol Rev. 2004 Dec;2(Suppl. 2):285-291.
    • Pediatr Endocrinol Rev , vol.2 , Issue.SUPPL. 2 , pp. 285-291
    • Gamberini, M.R.1    Fortini, M.2    de Sanctis, V.3    Gilli, G.4    Testa, M.R.5
  • 8
    • 0141705304 scopus 로고    scopus 로고
    • Labile plasma iron in iron overload: Redox activity and susceptibility to chelation
    • 2003 Oct 1
    • Esposito BP, Breuer W, Sirankapracha P, Pootrakul P, Hershko C, Cabantchik ZI. Labile plasma iron in iron overload: redox activity and susceptibility to chelation. Blood. 2003 Oct 1;102(7):2670-2677.
    • Blood , vol.102 , Issue.7 , pp. 2670-2677
    • Esposito, B.P.1    Breuer, W.2    Sirankapracha, P.3    Pootrakul, P.4    Hershko, C.5    Cabantchik, Z.I.6
  • 9
    • 29844457587 scopus 로고    scopus 로고
    • The evolution of iron chelators for the treatment of iron overload disease and cancer
    • 2005 Dec
    • Kalinowski DS, Richardson DR. The evolution of iron chelators for the treatment of iron overload disease and cancer. Pharmacol Rev. 2005 Dec;57(4):547-583.
    • Pharmacol Rev , vol.57 , Issue.4 , pp. 547-583
    • Kalinowski, D.S.1    Richardson, D.R.2
  • 10
    • 3042821747 scopus 로고    scopus 로고
    • Iron chelators and their therapeutic potential
    • Crichton RR, Ward RJ. Iron chelators and their therapeutic potential. Met Ions Biol Syst. 2004;41:185-219.
    • (2004) Met Ions Biol Syst , vol.41 , pp. 185-219
    • Crichton, R.R.1    Ward, R.J.2
  • 12
    • 0036236081 scopus 로고    scopus 로고
    • Impact of thalassemia major on patients and their families
    • Caro JJ, Ward A, Green TC, et al. Impact of thalassemia major on patients and their families. Acta Haematol. 2002;107(3):150-157.
    • (2002) Acta Haematol , vol.107 , Issue.3 , pp. 150-157
    • Caro, J.J.1    Ward, A.2    Green, T.C.3
  • 13
    • 0030048681 scopus 로고    scopus 로고
    • Results of long-term iron-chelating therapy
    • Gabutti V, Piga A. Results of long-term iron-chelating therapy. Acta Haematol. 1996;95(1):26-36.
    • (1996) Acta Haematol , vol.95 , Issue.1 , pp. 26-36
    • Gabutti, V.1    Piga, A.2
  • 14
    • 0036420133 scopus 로고    scopus 로고
    • Growth and puberty and its management in thalassaemia
    • De Sanctis V. Growth and puberty and its management in thalassaemia. Horm Res. 2002;58(Suppl. 1):72-79.
    • (2002) Horm Res , vol.58 , Issue.SUPPL. 1 , pp. 72-79
    • de Sanctis, V.1
  • 16
    • 52049092607 scopus 로고    scopus 로고
    • Spermatogenesis in young adult patients with beta-thalassaemia major long-term treated with desferrioxamine
    • 2008 Mar
    • De Sanctis V, Borsari G, Brachi S, Govoni M, Carandina G. Spermatogenesis in young adult patients with beta-thalassaemia major long-term treated with desferrioxamine. Georgian Med News. 2008 Mar(156):74-77.
    • Georgian Med News , Issue.156 , pp. 74-77
    • de Sanctis, V.1    Borsari, G.2    Brachi, S.3    Govoni, M.4    Carandina, G.5
  • 17
    • 7944230624 scopus 로고    scopus 로고
    • Myocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: A prospective study using T2* cardiovascular magnetic resonance
    • 2004 Nov
    • Anderson LJ, Westwood MA, Holden S, et al. Myocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: a prospective study using T2* cardiovascular magnetic resonance. Br J Haematol. 2004 Nov;127(3):348-355.
    • Br J Haematol , vol.127 , Issue.3 , pp. 348-355
    • Anderson, L.J.1    Westwood, M.A.2    Holden, S.3
  • 18
    • 0031784438 scopus 로고    scopus 로고
    • Combined therapy with deferiprone and desferrioxamine
    • 1998 Nov
    • Wonke B, Wright C, Hoffbrand AV. Combined therapy with deferiprone and desferrioxamine. Br J Haematol. 1998 Nov;103(2):361-364.
    • Br J Haematol , vol.103 , Issue.2 , pp. 361-364
    • Wonke, B.1    Wright, C.2    Hoffbrand, A.V.3
  • 19
    • 0003305345 scopus 로고    scopus 로고
    • Optimising chelation therapy: Combining deferiprone and deferoxamine
    • Grady R, Berdoukas V, Rachmielewitz EA, Giardina PJ. Optimising chelation therapy: Combining deferiprone and deferoxamine. Blood 2000, 96:604a.
    • (2000) Blood , vol.96
    • Grady, R.1    Berdoukas, V.2    Rachmielewitz, E.A.3    Giardina, P.J.4
  • 20
    • 0038187626 scopus 로고    scopus 로고
    • Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: A retrospective analysis
    • 2003 May
    • Piga A, Gaglioti C, Fogliacco E, Tricta F. Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: a retrospective analysis. Haematologica. 2003 May;88(5):489-496.
    • Haematologica , vol.88 , Issue.5 , pp. 489-496
    • Piga, A.1    Gaglioti, C.2    Fogliacco, E.3    Tricta, F.4
  • 21
    • 33646407268 scopus 로고    scopus 로고
    • Cardiac morbidity and mortality in deferoxamine- or deferiprone-treated patients with thalassemiamajor
    • 2006 May 1
    • Borgna-Pignatti C, Cappellini MD, De Stefano P, et al. Cardiac morbidity and mortality in deferoxamine- or deferiprone-treated patients with thalassemiamajor. Blood. 2006 May 1;107(9):3733-3737.
    • Blood , vol.107 , Issue.9 , pp. 3733-3737
    • Borgna-Pignatti, C.1    Cappellini, M.D.2    de Stefano, P.3
  • 22
    • 0037125595 scopus 로고    scopus 로고
    • Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia
    • 2002 Aug 17
    • Anderson LJ, Wonke B, Prescott E, Holden S, Walker JM, Pennell DJ. Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia. Lancet. 2002 Aug 17; 360(9332):516-520.
    • Lancet , vol.360 , Issue.9332 , pp. 516-520
    • Anderson, L.J.1    Wonke, B.2    Prescott, E.3    Holden, S.4    Walker, J.M.5    Pennell, D.J.6
  • 23
    • 33646387405 scopus 로고    scopus 로고
    • Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis
    • 2006 May 1
    • Pennell DJ, Berdoukas V, Karagiorga M, et al. Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis. Blood. 2006 May 1;107(9):3738-3744.
    • Blood , vol.107 , Issue.9 , pp. 3738-3744
    • Pennell, D.J.1    Berdoukas, V.2    Karagiorga, M.3
  • 24
    • 0037630378 scopus 로고    scopus 로고
    • Role of deferiprone in chelation therapy for transfusional iron overload
    • 2003 Jul 1
    • Hoffbrand AV, Cohen A, Hershko C. Role of deferiprone in chelation therapy for transfusional iron overload. Blood. 2003 Jul 1;102(1):17-24.
    • Blood , vol.102 , Issue.1 , pp. 17-24
    • Hoffbrand, A.V.1    Cohen, A.2    Hershko, C.3
  • 25
    • 0042943205 scopus 로고    scopus 로고
    • Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone
    • 2003 Sep 1
    • Cohen AR, Galanello R, Piga A, De Sanctis V, Tricta F. Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone. Blood. 2003 Sep 1;102(5):1583-1587.
    • Blood , vol.102 , Issue.5 , pp. 1583-1587
    • Cohen, A.R.1    Galanello, R.2    Piga, A.3    de Sanctis, V.4    Tricta, F.5
  • 26
    • 0033520468 scopus 로고    scopus 로고
    • 4-[3,5-Bis(2- hydroxyphenyl)-1,2,4-triazol-1-yl]-benzoic acid: A novel efficient and selective iron(III) complexing agent
    • Ed 38
    • Heinz HH, Acklin P, Faller B, Lattmann R, Schnebli HP. 4-[3,5-Bis(2- hydroxyphenyl)-1,2,4-triazol-1-yl]-benzoic acid: a novel efficient and selective iron(III) complexing agent. Angew Chem Int. 1999(Ed 38): 2568-2570.
    • (1999) Angew Chem Int , pp. 2568-2570
    • Heinz, H.H.1    Acklin, P.2    Faller, B.3    Lattmann, R.4    Schnebli, H.P.5
  • 27
    • 77950682176 scopus 로고    scopus 로고
    • Tailoring iron chelation by iron intake and serum ferritin: The prospective EPIC study of deferasirox in 1744 patients with transfusion-dependent anemias
    • 2010 Apr
    • Cappellini MD, Porter J, El-Beshlawy A, et al. Tailoring iron chelation by iron intake and serum ferritin: the prospective EPIC study of deferasirox in 1744 patients with transfusion-dependent anemias. Haematologica. 2010 Apr;95(4):557-566.
    • Haematologica , vol.95 , Issue.4 , pp. 557-566
    • Cappellini, M.D.1    Porter, J.2    El-Beshlawy, A.3
  • 28
    • 70449403619 scopus 로고    scopus 로고
    • Efficacy and safety of deferasirox doses of -30 mg/kg per d in patients with transfusiondependent anaemia and iron overload
    • 2009 Dec
    • Taher A, Cappellini MD, Vichinsky E, et al. Efficacy and safety of deferasirox doses of -30 mg/kg per d in patients with transfusiondependent anaemia and iron overload. Br J Haematol. 2009 Dec;147(5): 752-759.
    • Br J Haematol , vol.147 , Issue.5 , pp. 752-759
    • Taher, A.1    Cappellini, M.D.2    Vichinsky, E.3
  • 29
    • 77953779950 scopus 로고    scopus 로고
    • The effect of deferasirox on cardiac iron in thalassemia major: Impact of total body iron stores
    • 2010 Jul 29
    • Wood JC, Kang BP, Thompson A, et al. The effect of deferasirox on cardiac iron in thalassemia major: impact of total body iron stores. Blood. 2010 Jul 29;116(4):537-543.
    • Blood , vol.116 , Issue.4 , pp. 537-543
    • Wood, J.C.1    Kang, B.P.2    Thompson, A.3
  • 30
    • 77950617863 scopus 로고    scopus 로고
    • Efficacy of deferasirox in reducing and preventing cardiac iron overload in beta-thalassemia
    • 2010 Mar 25
    • Pennell DJ, Porter JB, Cappellini MD, et al. Efficacy of deferasirox in reducing and preventing cardiac iron overload in beta-thalassemia. Blood. 2010 Mar 25;115(12):2364-2371.
    • Blood , vol.115 , Issue.12 , pp. 2364-2371
    • Pennell, D.J.1    Porter, J.B.2    Cappellini, M.D.3
  • 31
    • 33646391919 scopus 로고    scopus 로고
    • Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: New data, new questions
    • 2006 May 1
    • Neufeld EJ. Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: new data, new questions. Blood. 2006 May 1;107(9):3436-3441.
    • Blood , vol.107 , Issue.9 , pp. 3436-3441
    • Neufeld, E.J.1
  • 32
    • 79956079114 scopus 로고    scopus 로고
    • Reported patient deaths increased by 14% in 2009
    • Reported patient deaths increased by 14% in 2009. ISMP Med Saf Alert. 2010;15(12):1-2.
    • (2010) ISMP Med Saf Alert , vol.15 , Issue.12 , pp. 1-2
  • 33
    • 0034783438 scopus 로고    scopus 로고
    • Chelation therapy in beta-thalassemia: An optimistic update
    • 2001 Oct
    • Giardina PJ, Grady RW. Chelation therapy in beta-thalassemia: an optimistic update. Semin Hematol. 2001 Oct;38(4):360-366.
    • Semin Hematol , vol.38 , Issue.4 , pp. 360-366
    • Giardina, P.J.1    Grady, R.W.2
  • 34
    • 77955379581 scopus 로고    scopus 로고
    • Mechanisms for the shuttling of plasma non-transferrin-bound iron (NTBI) onto deferoxamine by deferiprone
    • 2010 Aug
    • Evans P, Kayyali R, Hider RC, Eccleston J, Porter JB. Mechanisms for the shuttling of plasma non-transferrin-bound iron (NTBI) onto deferoxamine by deferiprone. Transl Res. 2010 Aug;156(2):55-67.
    • Transl Res , vol.156 , Issue.2 , pp. 55-67
    • Evans, P.1    Kayyali, R.2    Hider, R.C.3    Eccleston, J.4    Porter, J.B.5
  • 35
    • 0347363715 scopus 로고    scopus 로고
    • Combined therapy with desferrioxamine and deferiprone in thalassemic patients: Effect on urinary iron excretion
    • 2003 Dec
    • Kattamis A, Kassou C, Berdousi H, Ladis V, Papassotiriou I, Kattamis C. Combined therapy with desferrioxamine and deferiprone in thalassemic patients: effect on urinary iron excretion. Haematologica. 2003 Dec;88(12):1423-1425.
    • Haematologica , vol.88 , Issue.12 , pp. 1423-1425
    • Kattamis, A.1    Kassou, C.2    Berdousi, H.3    Ladis, V.4    Papassotiriou, I.5    Kattamis, C.6
  • 36
    • 74049116227 scopus 로고    scopus 로고
    • Normalisation of total body iron load with very intensive combined chelation reverses cardiac and endocrine complications of thalassaemia major
    • 2010 Feb
    • Farmaki K, Tzoumari I, Pappa C, Chouliaras G, Berdoukas V. Normalisation of total body iron load with very intensive combined chelation reverses cardiac and endocrine complications of thalassaemia major. Br J Haematol. 2010 Feb;148(3):466-475.
    • Br J Haematol , vol.148 , Issue.3 , pp. 466-475
    • Farmaki, K.1    Tzoumari, I.2    Pappa, C.3    Chouliaras, G.4    Berdoukas, V.5
  • 37
    • 0035865702 scopus 로고    scopus 로고
    • ICL670A: A new synthetic oral chelator: Evaluation in hypertransfused rats with selective radioiron probes of hepatocellular and reticuloendothelial iron stores and in iron-loaded rat heart cells in culture
    • 2001 Feb 15
    • Hershko C, Konijn AM, Nick HP, Breuer W, Cabantchik ZI, Link G. ICL670A: a new synthetic oral chelator: evaluation in hypertransfused rats with selective radioiron probes of hepatocellular and reticuloendothelial iron stores and in iron-loaded rat heart cells in culture. Blood. 2001 Feb 15;97(4):1115-1122.
    • Blood , vol.97 , Issue.4 , pp. 1115-1122
    • Hershko, C.1    Konijn, A.M.2    Nick, H.P.3    Breuer, W.4    Cabantchik, Z.I.5    Link, G.6
  • 38
    • 77955891235 scopus 로고    scopus 로고
    • Retrospective study on the combination of desferrioxamine and deferasirox for treatment of iron-overloaded thalassemic patients: First evidence of more than 2 years
    • 2010 Jul
    • Jetsrisuparb A, Komvilaisak P, Wiangnon S, Jetsrisuparb C. Retrospective study on the combination of desferrioxamine and deferasirox for treatment of iron-overloaded thalassemic patients: first evidence of more than 2 years. J Pediatr Hematol Oncol. 2010 Jul;32(5):400-403.
    • J Pediatr Hematol Oncol , vol.32 , Issue.5 , pp. 400-403
    • Jetsrisuparb, A.1    Komvilaisak, P.2    Wiangnon, S.3    Jetsrisuparb, C.4
  • 39
    • 79956157832 scopus 로고    scopus 로고
    • Safety of Deferasirox and Deferiprone Combined Chelation Therapy in Thalassemia Major Blood (ASH Annual Meeting Abstracts)
    • Lal A SN, Ng V, Foote D, Neumayer L, Kurio G, Harmatz P, Porter J, Vichinsky E. Safety of Deferasirox and Deferiprone Combined Chelation Therapy in Thalassemia Major Blood (ASH Annual Meeting Abstracts), Nov 2010; 116:4269. 2009.
    • (2009) Nov 2010; 116 , pp. 4269
    • Lal, A.S.N.1    Ng, V.2    Foote, D.3    Neumayer, L.4    Kurio, G.5    Harmatz, P.6    Porter, J.7    Vichinsky, E.8
  • 40
    • 77953069934 scopus 로고    scopus 로고
    • Daily alternating deferasirox and deferiprone therapy for ''hard-to-chelate'' beta-thalassemiamajor patients
    • 2010 Jun
    • Balocco M, Carrara P, Pinto V, Forni GL. Daily alternating deferasirox and deferiprone therapy for ''hard-to-chelate'' beta-thalassemiamajor patients. Am J Hematol. 2010 Jun;85(6):460-461.
    • Am J Hematol , vol.85 , Issue.6 , pp. 460-461
    • Balocco, M.1    Carrara, P.2    Pinto, V.3    Forni, G.L.4
  • 43
    • 73949118610 scopus 로고    scopus 로고
    • New concept in natural history and management of diabetes mellitus in thalassemia major
    • Chatterjee R, Bajoria R. New concept in natural history and management of diabetes mellitus in thalassemia major. Hemoglobin. 2009;33(Suppl. 1):S127-S130.
    • (2009) Hemoglobin , vol.33 , Issue.SUPPL. 1
    • Chatterjee, R.1    Bajoria, R.2
  • 44
    • 33748742706 scopus 로고    scopus 로고
    • Combined chelation therapy improves glucose metabolism in patients with betathalassaemia major
    • 2006 Oct
    • Christoforidis A, Perifanis V, Athanassiou-Metaxa M. Combined chelation therapy improves glucose metabolism in patients with betathalassaemia major. Br J Haematol. 2006 Oct;135(2):271-272.
    • Br J Haematol , vol.135 , Issue.2 , pp. 271-272
    • Christoforidis, A.1    Perifanis, V.2    Athanassiou-Metaxa, M.3
  • 45
    • 12544253460 scopus 로고    scopus 로고
    • Glucose metabolism disorders improvement in patients with thalassaemia major after 24-36 months of intensive chelation therapy
    • 2004 Dec
    • Platis O, Anagnostopoulos G, Farmaki K, Posantzis M, Gotsis E, Tolis G. Glucose metabolism disorders improvement in patients with thalassaemia major after 24-36 months of intensive chelation therapy. Pediatr Endocrinol Rev. 2004 Dec;2(Suppl. 2):279-281.
    • Pediatr Endocrinol Rev , vol.2 , Issue.SUPPL. 2 , pp. 279-281
    • Platis, O.1    Anagnostopoulos, G.2    Farmaki, K.3    Posantzis, M.4    Gotsis, E.5    Tolis, G.6
  • 46
    • 33746049146 scopus 로고    scopus 로고
    • Effect of enhanced iron chelation therapy on glucose metabolism in patients with beta-thalassaemia major
    • 2006 Aug
    • Farmaki K, Angelopoulos N, Anagnostopoulos G, Gotsis E, Rombopoulos G, Tolis G. Effect of enhanced iron chelation therapy on glucose metabolism in patients with beta-thalassaemia major. Br J Haematol. 2006 Aug;134(4):438-444.
    • Br J Haematol , vol.134 , Issue.4 , pp. 438-444
    • Farmaki, K.1    Angelopoulos, N.2    Anagnostopoulos, G.3    Gotsis, E.4    Rombopoulos, G.5    Tolis, G.6
  • 47
    • 0036154148 scopus 로고    scopus 로고
    • WHO and ADA criteria for the diagnosis of diabetes mellitus in relation to body mass index. Insulin sensitivity and secretion in resulting subcategories of glucose tolerance
    • 2002 Jan
    • Melchionda N, Forlani G, Marchesini G, Baraldi L, Natale S. WHO and ADA criteria for the diagnosis of diabetes mellitus in relation to body mass index. Insulin sensitivity and secretion in resulting subcategories of glucose tolerance. Int J Obes Relat Metab Disord. 2002 Jan;26(1):90-96.
    • Int J Obes Relat Metab Disord , vol.26 , Issue.1 , pp. 90-96
    • Melchionda, N.1    Forlani, G.2    Marchesini, G.3    Baraldi, L.4    Natale, S.5
  • 48
    • 79951519154 scopus 로고    scopus 로고
    • The diagnosis and management of heredi-tary haemochromatosis
    • 2010 Feb
    • Clark P, Britton LJ, Powell LW. The diagnosis and management of heredi-tary haemochromatosis. Clin Biochem Rev. 2010 Feb;31(1):3-8.
    • Clin Biochem Rev , vol.31 , Issue.1 , pp. 3-8
    • Clark, P.1    Britton, L.J.2    Powell, L.W.3
  • 49
    • 76949115949 scopus 로고    scopus 로고
    • Hemochromatosis; investigation of twenty-three cases, with special reference to etiology, nutrition, iron metabolism, and studies of hepatic and pancreatic function
    • 1951 Nov
    • Althausen TL, Doig RK, Weiden S, Motteram R, Turner CN, Moore A. Hemochromatosis; investigation of twenty-three cases, with special reference to etiology, nutrition, iron metabolism, and studies of hepatic and pancreatic function. AMA Arch Intern Med. 1951 Nov;88(5):553-570.
    • AMA Arch Intern Med , vol.88 , Issue.5 , pp. 553-570
    • Althausen, T.L.1    Doig, R.K.2    Weiden, S.3    Motteram, R.4    Turner, C.N.5    Moore, A.6
  • 50
    • 18044399191 scopus 로고    scopus 로고
    • Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload
    • 2001 Dec
    • Anderson LJ, Holden S, Davis B, et al. Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J. 2001 Dec;22(23):2171-2179.
    • Eur Heart J , vol.22 , Issue.23 , pp. 2171-2179
    • Anderson, L.J.1    Holden, S.2    Davis, B.3
  • 51
    • 75649124518 scopus 로고    scopus 로고
    • Magnetic resonance imaging signal reduction may precede volume loss in the pituitary gland of transfusion-dependent beta-thalassemic patients
    • 2010 Feb
    • Hekmatnia A, Radmard AR, Rahmani AA, Adibi A, Khademi H. Magnetic resonance imaging signal reduction may precede volume loss in the pituitary gland of transfusion-dependent beta-thalassemic patients. Acta Radiol. 2010 Feb;51(1):71-77.
    • Acta Radiol , vol.51 , Issue.1 , pp. 71-77
    • Hekmatnia, A.1    Radmard, A.R.2    Rahmani, A.A.3    Adibi, A.4    Khademi, H.5
  • 52
    • 38449083247 scopus 로고    scopus 로고
    • Utility of MRI in assessment of pituitary iron overload
    • 2007 Sep
    • Zafar AM, Zuberi L, Khan AH, Ahsan H. Utility of MRI in assessment of pituitary iron overload. J Pak Med Assoc. 2007 Sep;57(9):475-477.
    • J Pak Med Assoc , vol.57 , Issue.9 , pp. 475-477
    • Zafar, A.M.1    Zuberi, L.2    Khan, A.H.3    Ahsan, H.4
  • 53
    • 77950442762 scopus 로고    scopus 로고
    • Pancreatic iron loading predicts cardiac iron loading in thalassemia major
    • 2009 Nov 5
    • Noetzli LJ, Papudesi J, Coates TD, Wood JC. Pancreatic iron loading predicts cardiac iron loading in thalassemia major. Blood. 2009 Nov 5;114(19):4021-4026.
    • Blood , vol.114 , Issue.19 , pp. 4021-4026
    • Noetzli, L.J.1    Papudesi, J.2    Coates, T.D.3    Wood, J.C.4
  • 54
    • 34248654567 scopus 로고    scopus 로고
    • The pancreas in betathalassemia major: MR imaging features and correlation with iron stores and glucose disturbances
    • 2007 Jun
    • Papakonstantinou O, Ladis V, Kostaridou S, et al. The pancreas in betathalassemia major: MR imaging features and correlation with iron stores and glucose disturbances. Eur Radiol. 2007 Jun;17(6):1535-1543.
    • Eur Radiol , vol.17 , Issue.6 , pp. 1535-1543
    • Papakonstantinou, O.1    Ladis, V.2    Kostaridou, S.3
  • 55
    • 69249157345 scopus 로고    scopus 로고
    • Organ-specific hemosiderosis and functional correlation in Chinese patients with thalassemia intermedia and hemoglobin H disease
    • 2009 Oct
    • Au WY, Lam WW, Chu WW, et al. Organ-specific hemosiderosis and functional correlation in Chinese patients with thalassemia intermedia and hemoglobin H disease. Ann Hematol. 2009 Oct;88(10):947-950.
    • Ann Hematol , vol.88 , Issue.10 , pp. 947-950
    • Au, W.Y.1    Lam, W.W.2    Chu, W.W.3
  • 56
    • 33646351076 scopus 로고    scopus 로고
    • Role of L-type Ca2- channels in iron transport and iron-overload cardiomyopathy
    • 2006 May
    • Oudit GY, Trivieri MG, Khaper N, Liu PP, Backx PH. Role of L-type Ca2- channels in iron transport and iron-overload cardiomyopathy. J Mol Med. 2006 May;84(5):349-364.
    • J Mol Med , vol.84 , Issue.5 , pp. 349-364
    • Oudit, G.Y.1    Trivieri, M.G.2    Khaper, N.3    Liu, P.P.4    Backx, P.H.5
  • 57
    • 38549150853 scopus 로고    scopus 로고
    • A T2* magnetic resonance imaging study of pancreatic iron overload in thalassemiamajor
    • 2008 Jan
    • Au WY, Lam WW, Chu W, et al. A T2* magnetic resonance imaging study of pancreatic iron overload in thalassemiamajor. Haematologica. 2008 Jan;93(1):116-119.
    • Haematologica , vol.93 , Issue.1 , pp. 116-119
    • Au, W.Y.1    Lam, W.W.2    Chu, W.3
  • 58
    • 27644539382 scopus 로고    scopus 로고
    • Intracellular labile iron pools as direct targets of iron chelators: A fluorescence study of chelator action in living cells
    • 2005 Nov 1
    • Glickstein H, El RB, Shvartsman M, Cabantchik ZI. Intracellular labile iron pools as direct targets of iron chelators: a fluorescence study of chelator action in living cells. Blood. 2005 Nov 1;106(9):3242-3250.
    • Blood , vol.106 , Issue.9 , pp. 3242-3250
    • Glickstein, H.1    El, R.B.2    Shvartsman, M.3    Cabantchik, Z.I.4
  • 59
    • 33746074849 scopus 로고    scopus 로고
    • Reduced insulin secretion in normoglycaemic patients with beta-thalassaemia major
    • 2006 Dec
    • Angelopoulos NG, Zervas A, Livadas S, et al. Reduced insulin secretion in normoglycaemic patients with beta-thalassaemia major. Diabet Med. 2006 Dec;23(12):1327-1331
    • Diabet Med , vol.23 , Issue.12 , pp. 1327-1331
    • Angelopoulos, N.G.1    Zervas, A.2    Livadas, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.