-
1
-
-
34848848499
-
-
Müller, K.; Faeh, C.; Diederich, F. Science 2007, 317, 1881
-
(2007)
Science
, vol.317
, pp. 1881
-
-
Müller, K.1
Faeh, C.2
Diederich, F.3
-
2
-
-
4444355871
-
-
Böhm, H.-J.; Banner, D.; Bendels, S.; Kansy, M.; Kuhn, B.; Müller, K.; Obst-Sander, U.; Stahl, M. ChemBioChem 2004, 5, 637
-
(2004)
ChemBioChem
, vol.5
, pp. 637
-
-
Böhm, H.-J.1
Banner, D.2
Bendels, S.3
Kansy, M.4
Kuhn, B.5
Müller, K.6
Obst-Sander, U.7
Stahl, M.8
-
4
-
-
4544240958
-
-
Gerebtzoff, G.; Li-Blatter, X.; Fischer, H.; Frentzel, A.; Seelig, A. ChemBioChem 2004, 5, 676
-
(2004)
ChemBioChem
, vol.5
, pp. 676
-
-
Gerebtzoff, G.1
Li-Blatter, X.2
Fischer, H.3
Frentzel, A.4
Seelig, A.5
-
8
-
-
54549103372
-
-
Furuya, T.; Kuttruff, C. A.; Ritter, T. Curr. Opin. Drug Discovery Dev. 2008, 11, 803
-
(2008)
Curr. Opin. Drug Discovery Dev.
, vol.11
, pp. 803
-
-
Furuya, T.1
Kuttruff, C.A.2
Ritter, T.3
-
9
-
-
44849112165
-
-
Ametamey, S. M.; Honer, M.; Schubiger, P. A. Chem. Rev. 2008, 108, 1501
-
(2008)
Chem. Rev.
, vol.108
, pp. 1501
-
-
Ametamey, S.M.1
Honer, M.2
Schubiger, P.A.3
-
10
-
-
77952537955
-
-
Recent examples using diaryliodonium salts, see
-
Recent examples using diaryliodonium salts, see: Chun, J.-H.; Lu, S.; Lee, Y.-S.; Pike, V. W. J. Org. Chem. 2010, 75, 3332
-
(2010)
J. Org. Chem.
, vol.75
, pp. 3332
-
-
Chun, J.-H.1
Lu, S.2
Lee, Y.-S.3
Pike, V.W.4
-
11
-
-
77955161058
-
-
NAr reaction, see:; J. Am. Chem. Soc. 2005, 127, 2050
-
NAr reaction, see: Sun, H.; DiMagno, S. G. J. Am. Chem. Soc. 2005, 127, 2050
-
(2010)
Org. Lett.
, vol.12
, pp. 3352
-
-
Wang, B.1
Qin, L.2
Neumann, K.D.3
Uppaluri, S.4
Cerny, R.L.5
Dimagno, S.G.6
Furuya, T.7
Ritter, T.8
Sun, H.9
Dimagno, S.G.10
-
12
-
-
33746255373
-
-
Using Balz-Schiemann reaction, see:; Angew. Chem., Int. Ed. 2010, 49, 5986
-
Sun, H.; DiMagno, S. G. Angew. Chem., Int. Ed. 2006, 45, 2720 Using Balz-Schiemann reaction, see: Döbele, M.; Vanderheiden, S.; Jung, N.; Bräse, S. Angew. Chem., Int. Ed. 2010, 49, 5986
-
(2006)
Angew. Chem., Int. Ed.
, vol.45
, pp. 2720
-
-
Sun, H.1
Dimagno, S.G.2
Döbele, M.3
Vanderheiden, S.4
Jung, N.5
Bräse, S.6
-
13
-
-
23044464175
-
-
Zhang, A.; Csutoras, C.; Zong, R.; Neumeyer, J. L. Org. Lett. 2005, 7, 3239
-
(2005)
Org. Lett.
, vol.7
, pp. 3239
-
-
Zhang, A.1
Csutoras, C.2
Zong, R.3
Neumeyer, J.L.4
-
14
-
-
67749097780
-
-
Furuya, T.; Strom, A. E.; Ritter, T. J. Am. Chem. Soc. 2009, 131, 1662
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 1662
-
-
Furuya, T.1
Strom, A.E.2
Ritter, T.3
-
15
-
-
70349527578
-
-
Watson, D. A.; Su, M.; Teverovskiy, G.; Zhang, Y.; Garcia-Fortanet, J.; Kinzel, T.; Buchwald, S. L. Science 2009, 325, 1661
-
(2009)
Science
, vol.325
, pp. 1661
-
-
Watson, D.A.1
Su, M.2
Teverovskiy, G.3
Zhang, Y.4
Garcia-Fortanet, J.5
Kinzel, T.6
Buchwald, S.L.7
-
16
-
-
70450182123
-
-
references cited therein.
-
Korkina, L. G.; De Luca, C.; Kostyuk, V. A.; Pastore, S. Curr. Med. Chem. 2009, 16, 3943 and references cited therein.
-
(2009)
Curr. Med. Chem.
, vol.16
, pp. 3943
-
-
Korkina, L.G.1
De Luca, C.2
Kostyuk, V.A.3
Pastore, S.4
-
17
-
-
0022536983
-
-
Kirk, K. L.; Olubajo, O.; Buchhold, K.; Lewandowski, G. A.; Gusovsky, F.; McCulloh, D.; Daly, J. W.; Creveling, C. R. J. Med. Chem. 1986, 29, 1982
-
(1986)
J. Med. Chem.
, vol.29
, pp. 1982
-
-
Kirk, K.L.1
Olubajo, O.2
Buchhold, K.3
Lewandowski, G.A.4
Gusovsky, F.5
McCulloh, D.6
Daly, J.W.7
Creveling, C.R.8
-
18
-
-
0025064444
-
-
Claudi, F.; Cardellini, M.; Cingolani, G. M.; Piergentili, A.; Peruzzi, G.; Balduini, W. J. Med. Chem. 1990, 33, 2408
-
(1990)
J. Med. Chem.
, vol.33
, pp. 2408
-
-
Claudi, F.1
Cardellini, M.2
Cingolani, G.M.3
Piergentili, A.4
Peruzzi, G.5
Balduini, W.6
-
19
-
-
0026053699
-
-
Ferrari, F.; Claudi, F. Pharmacol., Biochem. Behav. 1991, 38, 131
-
(1991)
Pharmacol., Biochem. Behav.
, vol.38
, pp. 131
-
-
Ferrari, F.1
Claudi, F.2
-
20
-
-
33646079653
-
-
Recent examples, see
-
Recent examples, see: Pravst, I.; Iskra, M. P.; Jereb, M.; Zupan, M.; Stavber, S. Tetrahedron 2006, 62, 4474
-
(2006)
Tetrahedron
, vol.62
, pp. 4474
-
-
Pravst, I.1
Iskra, M.P.2
Jereb, M.3
Zupan, M.4
Stavber, S.5
-
21
-
-
67849121879
-
-
Kitevski-LeBlanc, J. L.; Al-Abdul-Wahid, M. S.; Prosser., R. S. J. Am. Chem. Soc. 2009, 131, 2054
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 2054
-
-
Kitevski-Leblanc, J.L.1
Al-Abdul-Wahid, M.S.2
Prosser, R.S.3
-
22
-
-
61449254558
-
-
Sugimoto, Y.; Konoki, K.; Murata, M.; Matsushita, M.; Kanazawa, H.; Oishi, T. J. Med. Chem. 2009, 52, 798
-
(2009)
J. Med. Chem.
, vol.52
, pp. 798
-
-
Sugimoto, Y.1
Konoki, K.2
Murata, M.3
Matsushita, M.4
Kanazawa, H.5
Oishi, T.6
-
23
-
-
30444442996
-
-
May, J. A.; Dantanarayana, A. P.; Zinke, P. W.; McLaughlin, M. A.; Sharif, N. A. J. Med. Chem. 2006, 49, 318
-
(2006)
J. Med. Chem.
, vol.49
, pp. 318
-
-
May, J.A.1
Dantanarayana, A.P.2
Zinke, P.W.3
McLaughlin, M.A.4
Sharif, N.A.5
-
24
-
-
1842790945
-
-
Curini, M.; Epifano, F.; Maltese, F.; Marcotullio, M. C.; Tubaro, A.; Altinier, G.; Gonzales, S. P.; Rodriguez, J. C. Bioorg. Med. Chem. Lett. 2004, 14, 2241
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 2241
-
-
Curini, M.1
Epifano, F.2
Maltese, F.3
Marcotullio, M.C.4
Tubaro, A.5
Altinier, G.6
Gonzales, S.P.7
Rodriguez, J.C.8
-
26
-
-
0022922558
-
-
Weinstock, J.; Gaitanopoulos, D.; Oh, H. J.; Pfeiffer, F. R.; Karash, C. B.; Venslavsky, J. W.; Sarau, H. M.; Flaim, K. E.; Hieble, J. P.; Kaiser, C. J. Med. Chem. 1986, 29, 1615
-
(1986)
J. Med. Chem.
, vol.29
, pp. 1615
-
-
Weinstock, J.1
Gaitanopoulos, D.2
Oh, H.J.3
Pfeiffer, F.R.4
Karash, C.B.5
Venslavsky, J.W.6
Sarau, H.M.7
Flaim, K.E.8
Hieble, J.P.9
Kaiser, C.10
-
28
-
-
79956138862
-
-
A contrasing experiments in our hands using cationic fluorine reagents, such as Selectfluor (1.0 equiv), (14a) for a catechol 1a at ambient temperature for 20 min resulted in forming the ortho -quinone 2a in 85% NMR yield without obtaining any fluoronated products.
-
A contrasing experiments in our hands using cationic fluorine reagents, such as Selectfluor (1.0 equiv), (14a) for a catechol 1a at ambient temperature for 20 min resulted in forming the ortho -quinone 2a in 85% NMR yield without obtaining any fluoronated products.
-
-
-
-
29
-
-
0001687697
-
-
Takata, T.; Tajima, R.; Ando, W. J. Org. Chem. 1983, 48, 4764
-
(1983)
J. Org. Chem.
, vol.48
, pp. 4764
-
-
Takata, T.1
Tajima, R.2
Ando, W.3
-
30
-
-
0033578943
-
-
Lal, G. S.; Pez, G. P.; Pesaresi, R. J.; Prozonic, F. M.; Cheng, H. J. Org. Chem. 1999, 64, 7048
-
(1999)
J. Org. Chem.
, vol.64
, pp. 7048
-
-
Lal, G.S.1
Pez, G.P.2
Pesaresi, R.J.3
Prozonic, F.M.4
Cheng, H.5
-
31
-
-
0344507270
-
-
Lal, G. S.; Pez, G. P.; Pesaresi, R. J.; Prozonic, F. M. Chem. Commun. 1999, 215
-
(1999)
Chem. Commun.
, pp. 215
-
-
Lal, G.S.1
Pez, G.P.2
Pesaresi, R.J.3
Prozonic, F.M.4
-
32
-
-
0035929389
-
-
Fluorination reactions of α-diketones and α-ketoacids using either Deoxofluor or DAST were reported, see
-
Fluorination reactions of α-diketones and α-ketoacids using either Deoxofluor or DAST were reported, see: Singh, R. P.; Majumder, U.; Shreeve, J. M. J. Org. Chem. 2001, 66, 6263
-
(2001)
J. Org. Chem.
, vol.66
, pp. 6263
-
-
Singh, R.P.1
Majumder, U.2
Shreeve, J.M.3
-
34
-
-
0009751387
-
-
A few examples of the cationic fluoronation of symmetric 4-alkylphenols were reported to give 4-alkyl-6,6-difluorocyclohexa-2,4-dienones, see
-
A few examples of the cationic fluoronation of symmetric 4-alkylphenols were reported to give 4-alkyl-6,6-difluorocyclohexa-2,4-dienones, see: Stavber, S.; Zupan, M. Synlett 1996, 693
-
(1996)
Synlett
, pp. 693
-
-
Stavber, S.1
Zupan, M.2
-
35
-
-
79956080371
-
-
DBU enhances the aromatization of the initial reduction products, 6,6-difluorocyclohexa-2,4-dienols.
-
DBU enhances the aromatization of the initial reduction products, 6,6-difluorocyclohexa-2,4-dienols.
-
-
-
-
36
-
-
0001640743
-
-
Wriede, U.; Fernandez, M.; West, K. F.; Harcour, D.; Moore, H. W. J. Org. Chem. 1987, 52, 4485
-
(1987)
J. Org. Chem.
, vol.52
, pp. 4485
-
-
Wriede, U.1
Fernandez, M.2
West, K.F.3
Harcour, D.4
Moore, H.W.5
-
39
-
-
33947292856
-
-
Fetizon, M.; Balogh, V.; Golfier, M. J. Org. Chem. 1971, 36, 1339
-
(1971)
J. Org. Chem.
, vol.36
, pp. 1339
-
-
Fetizon, M.1
Balogh, V.2
Golfier, M.3
-
40
-
-
79956085242
-
-
2 (23c) smoothly proceeded in various organic solvents; however, they were less effective for the one-pot deoxyfluorination. The oxidation by Fetizon reagent (23d) was slow at room temperature, while the ortho -quinones gradually decomposed.
-
2 (23c) smoothly proceeded in various organic solvents; however, they were less effective for the one-pot deoxyfluorination. The oxidation by Fetizon reagent (23d) was slow at room temperature, while the ortho -quinones gradually decomposed.
-
-
-
-
41
-
-
0035793265
-
-
MgO was used in combination with the hypervalent iodine reagents to scavenge the generated acetic acid, see
-
MgO was used in combination with the hypervalent iodine reagents to scavenge the generated acetic acid, see: Espino, C. G.; Du Bois, J. Angew. Chem., Int. Ed. 2001, 40, 598
-
(2001)
Angew. Chem., Int. Ed.
, vol.40
, pp. 598
-
-
Espino, C.G.1
Du Bois, J.2
-
42
-
-
66149120700
-
-
Miller, L. A.; Marsini, M. A.; Pettus, T. R. R. Org. Lett. 2009, 11, 1955
-
(2009)
Org. Lett.
, vol.11
, pp. 1955
-
-
Miller, L.A.1
Marsini, M.A.2
Pettus, T.R.R.3
-
43
-
-
67649947129
-
-
Boric acid is also useful for the chemoselective, in situ protection of the catechol moiety of catechins, see
-
Boric acid is also useful for the chemoselective, in situ protection of the catechol moiety of catechins, see: Aihara, Y.; Yoshida, A.; Furuta, T.; Wakimoto, T.; Akizawa, T.; Konishi, M.; Kan, T. Bioorg. Med. Chem. Lett. 2009, 19, 4171
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 4171
-
-
Aihara, Y.1
Yoshida, A.2
Furuta, T.3
Wakimoto, T.4
Akizawa, T.5
Konishi, M.6
Kan, T.7
-
44
-
-
0029156879
-
-
Namavari, M.; Satyamurthy, N.; Barrio, J. R. J. Labelled Compd. Radiopharm. 1995, 36, 825
-
(1995)
J. Labelled Compd. Radiopharm.
, vol.36
, pp. 825
-
-
Namavari, M.1
Satyamurthy, N.2
Barrio, J.R.3
-
45
-
-
0026004356
-
-
Chirakal, R.; Schrobilgen, G. J.; Firnau, G.; Garnett, S. Appl. Radiat. Isot. 1991, 42, 113
-
(1991)
Appl. Radiat. Isot.
, vol.42
, pp. 113
-
-
Chirakal, R.1
Schrobilgen, G.J.2
Firnau, G.3
Garnett, S.4
|