Stictamides A-C, MMP12 inhibitors containing 4-amino-3-hydroxy-5- phenylpentanoic acid subunits

Journal of Organic Chemistry

Volumn 76, Issue 10, 2011, Pages 3635-3643

  Liang, Zhibin ^a   Sorribas, Analia ^a   Sulzmaier, Florian J ^b   Jiménez, Jorge I ^c   Wang, Xin ^a   Sauvage, Thomas ^a   Yoshida, Wesley Y ^a   Wang, Guangyi ^a   Ramos, Joe W ^b   Williams, Philip G ^a,b  

^a UNIVERSITY OF HAWAII   (United States)

^b UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^c AgraQuestm Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID HYDROLYSIS; ACID RESIDUES; CHEMICAL METHOD; EPIMERIZATION; GLIOMA CELL LINES; SECONDARY METABOLITES;

CELL CULTURE;

METABOLITES;

ADAM10 ENDOPEPTIDASE; ADAM9 PROTEIN; ANTINEOPLASTIC AGENT; BETA SECRETASE 1; CALPAIN; CASPASE 3; CASPASE 9; CATHEPSIN B; CATHEPSIN D; CATHEPSIN E; CHLOROTRIANISENE; CHYMOTRYPSIN; DIPEPTIDYL PEPTIDASE IV; ELASTASE; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE INHIBITOR; PROTEIN; STICTAMIDE A; STICTAMIDE B; STICTAMIDE C; TRYPSIN; UNCLASSIFIED DRUG; VALERIC ACID DERIVATIVE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL INVASION; CELL VIABILITY; CONTROLLED STUDY; DRUG ISOLATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME INHIBITION; EPIMERIZATION; GLIOMA CELL; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; HYDROLYSIS; LICHENS; NUCLEOTIDE SEQUENCE; STICTA;

AMINO ACIDS; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; MATRIX METALLOPROTEINASE 12; MODELS, MOLECULAR; NEOPLASM INVASIVENESS; PEPTIDES; PROTEASE INHIBITORS; PROTEIN CONFORMATION;

EID: 79956077135     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo200241h     Document Type: Article

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