Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 18, 1996, Pages 9748-9753

  Halpert, Igor ^a   Sires, Ulrike I ^a   Roby, Jill D ^a   Potter Perigo, Susan ^c   Wight, Thomas N ^c   Shapiro, Steven D ^a   Welgus, Howard G ^a   Wickline, Samuel A ^a   Parks, William C ^a,b  

^a BARNES JEWISH HOSPITAL   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

chondroitin sulfate; metalloelastase; metalloproteinase

Indexed keywords

MATRILYSIN; PROTEOCHONDROITIN SULFATE; VERSICAN;

ARTERY RUPTURE; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HUMAN TISSUE; MACROPHAGE FUNCTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STRUCTURE ANALYSIS;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; ARTERIOSCLEROSIS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCOPROTEINS; HUMANS; IN SITU HYBRIDIZATION; LECTINS, C-TYPE; MACROPHAGES; MATRIX METALLOPROTEINASE 12; MATRIX METALLOPROTEINASE 7; METALLOENDOPEPTIDASES; ORGAN CULTURE TECHNIQUES; PROTEASE INHIBITORS; PROTEOCHONDROITIN SULFATES; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASES; VERSICANS;

EID: 0029817688     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.18.9748     Document Type: Article

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