The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: Assessing pharmacological effects in preclinical species

Journal of Lipid Research

Volumn 52, Issue 6, 2011, Pages 1150-1161

  McLaren, David G ^a   He, Timothy ^a   Wang, Sheng Ping ^a   Mendoza, Vivienne ^a   Rosa, Raymond ^a   Gagen, Karen ^a   Bhat, Gowri ^a   Herath, Kithsiri ^a   Miller, Paul L ^a   Stribling, Sloan ^a   Taggart, Andrew ^a   Imbriglio, Jason ^a   Liu, Jinqi ^a   Chen, Dunlu ^a   Pinto, Shirly ^a   Balkovec, James M ^a   DeVita, Robert J ^a   Marsh, Donald J ^a   Castro Perez, Jose M ^a   Strack, Alison ^a   Johns, Douglas G ^a   Previs, Stephen F ^a   Hubbard, Brian K ^a   Roddy, Thomas P ^a   more..

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Cholesteryl ester; Diacylglycerol acyltransferase; Fatty acid; Liquid chromatography mass spectrometry; Mass isotopomer distribution analysis; Microsomal triglyceride transfer protein; Nonhuman primate; Phosphatidylcholine; Stable isotope tracer; Triglycerides

Indexed keywords

CARBON 13; CHOLESTEROL ESTER; DIACYLGLYCEROL ACYLTRANSFERASE 1; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN INHIBITOR; OLEIC ACID; PHOSPHOLIPID; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ARTICLE; CHLOROCEBUS; CONTROLLED STUDY; FEMALE; LIPOGENESIS; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CARRIER PROTEINS; CERCOPITHECUS AETHIOPS; CHOLESTEROL ESTERS; CHROMATOGRAPHY, LIQUID; DIACYLGLYCEROL O-ACYLTRANSFERASE; DRUG ADMINISTRATION ROUTES; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; FEMALE; ISOTOPE LABELING; ISOTOPES; LIPID METABOLISM; LIPOPROTEINS; MALE; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; OLEIC ACID; TRIGLYCERIDES;

EID: 79956054545     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M011049     Document Type: Article

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