-
1
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN, et al. APC mutations occur early during colorectal tumorigenesis. Nature 1992; 359:235-7.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
-
2
-
-
12044249989
-
Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP)
-
Ichii S, Takeda S, Horii A, Nakatsuru S, Miyoshi Y, Emi M, et al. Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP). Oncogene 1993; 8:2399-405. (Pubitemid 23252368)
-
(1993)
Oncogene
, vol.8
, Issue.9
, pp. 2399-2405
-
-
Ichii, S.1
Takeda, S.2
Horii, A.3
Nakatsuru, S.4
Miyoshi, Y.5
Emi, M.6
Fujiwara, Y.7
Koyama, K.8
Furuyama, J.9
Utsunomiya, J.10
Nakamura, Y.11
-
4
-
-
0033984493
-
The relationship between angiogenesis and the immune response in carcinogenesis and the progression of malignant disease
-
DOI 10.1016/S0959-8049(99)00241-5, PII S0959804999002415
-
O'Byrne KJ, Dalgleish AG, Browning MJ, Steward WP, Harris AL. The relationship between angiogenesis and the immune response in carcinogenesis and the progression of malignant disease. Eur J Cancer 2000; 36:151-69. (Pubitemid 30102191)
-
(2000)
European Journal of Cancer
, vol.36
, Issue.2
, pp. 151-169
-
-
O'Byrne, K.J.1
Dalgleish, A.G.2
Browning, M.J.3
Steward, W.P.4
Harris, A.L.5
-
5
-
-
54049122927
-
The role of hypoxia in recurrence following resection of Dukes' B colorectal cancer
-
Rajaganeshan R, Prasad R, Guillou PJ, Poston G, Scott N, Jayne DG. The role of hypoxia in recurrence following resection of Dukes' B colorectal cancer. Int J Colorectal Dis 2008; 23:1049-55.
-
(2008)
Int J Colorectal Dis
, vol.23
, pp. 1049-1055
-
-
Rajaganeshan, R.1
Prasad, R.2
Guillou, P.J.3
Poston, G.4
Scott, N.5
Jayne, D.G.6
-
6
-
-
0034644526
-
Linking colorectal cancer to Wnt signaling
-
Bienz M, Clevers H. Linking colorectal cancer to Wnt signaling. Cell 2000; 103:311-20.
-
(2000)
Cell
, vol.103
, pp. 311-320
-
-
Bienz, M.1
Clevers, H.2
-
7
-
-
41549117418
-
Cell regulation by the Apc protein Apc as master regulator of epithelia
-
McCartney BM, Nathke IS. Cell regulation by the Apc protein Apc as master regulator of epithelia. Curr Opin Cell Biol 2008; 20:186-93.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 186-193
-
-
McCartney, B.M.1
Nathke, I.S.2
-
8
-
-
33745328509
-
HIFing the brakes: Therapeutic opportunities for treatment of human malignancies
-
Garcia JA. HIFing the brakes: Therapeutic opportunities for treatment of human malignancies. Sci STKE 2006; 2006:25.
-
(2006)
Sci STKE
, vol.2006
, pp. 25
-
-
Garcia, J.A.1
-
9
-
-
22144493866
-
Negative and positive regulation of HIF-1: A complex network
-
DOI 10.1016/j.bbcan.2005.05.001, PII S0304419X05000211
-
Bardos JI, Ashcroft M. Negative and positive regulation of HIF-1: A complex network. Biochim Biophys Acta 2005; 1755:107-20. (Pubitemid 40982561)
-
(2005)
Biochimica et Biophysica Acta - Reviews on Cancer
, vol.1755
, Issue.2
, pp. 107-120
-
-
Bardos, J.I.1
Ashcroft, M.2
-
10
-
-
34547493149
-
Hydroxylation of hypoxia-inducible transcription factors and chemical compounds targeting the HIF-alpha hydroxylases
-
DOI 10.2174/092986707781058850
-
Bruegge K, Jelkmann W, Metzen E. Hydroxylation of hypoxia-inducible transcription factors and chemical compounds targeting the HIF-alpha hydroxylases. Curr Med Chem 2007; 14:1853-62. (Pubitemid 47163403)
-
(2007)
Current Medicinal Chemistry
, vol.14
, Issue.17
, pp. 1853-1862
-
-
Bruegge, K.1
Jelkmann, W.2
Metzen, E.3
-
11
-
-
33748187417
-
Regulating cellular oxygen sensing by hydroxylation
-
DOI 10.1016/j.cardiores.2006.05.005, PII S0008636306001891
-
Fandrey J, Gorr TA, Gassmann M. Regulating cellular oxygen sensing by hydroxylation. Cardiovasc Res 2006; 71:642-51. (Pubitemid 44848002)
-
(2006)
Cardiovascular Research
, vol.71
, Issue.4
, pp. 642-651
-
-
Fandrey, J.1
Gorr, T.A.2
Gassmann, M.3
-
12
-
-
49649108032
-
Regulation of gene expression by hypoxia
-
Kenneth NS, Rocha S. Regulation of gene expression by hypoxia. Biochem J 2008; 414:19-29.
-
(2008)
Biochem J
, vol.414
, pp. 19-29
-
-
Kenneth, N.S.1
Rocha, S.2
-
13
-
-
45349097483
-
Regulation of hypoxia-inducible factor-1alpha by NFkappaB
-
van Uden P, Kenneth NS, Rocha S. Regulation of hypoxia-inducible factor-1alpha by NFkappaB. Biochem J 2008; 412:477-84.
-
(2008)
Biochem J
, vol.412
, pp. 477-484
-
-
Van Uden, P.1
Kenneth, N.S.2
Rocha, S.3
-
14
-
-
79851471726
-
Evolutionary conserved regulation of HIF-1beta by NFkappaB
-
van Uden P, Kenneth NS, Webster R, Muller HA, Mudie S, Rocha S. Evolutionary conserved regulation of HIF-1beta by NFkappaB. PLoS Genet 2011; 7:1001285.
-
(2011)
PLoS Genet
, vol.7
, pp. 1001285
-
-
Van Uden, P.1
Kenneth, N.S.2
Webster, R.3
Muller, H.A.4
Mudie, S.5
Rocha, S.6
-
15
-
-
47149099173
-
The cross-talk between NFkappaB and HIF-1: Further evidence for a significant liaison
-
Gorlach A, Bonello S. The cross-talk between NFkappaB and HIF-1: further evidence for a significant liaison. Biochem J 2008; 412:17-9.
-
(2008)
Biochem J
, vol.412
, pp. 17-19
-
-
Gorlach, A.1
Bonello, S.2
-
16
-
-
44849100198
-
NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha
-
DOI 10.1038/nature06905, PII NATURE06905
-
Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, et al. NFkappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature 2008; 453:807-11. (Pubitemid 351793778)
-
(2008)
Nature
, vol.453
, Issue.7196
, pp. 807-811
-
-
Rius, J.1
Guma, M.2
Schachtrup, C.3
Akassoglou, K.4
Zinkernagel, A.S.5
Nizet, V.6
Johnson, R.S.7
Haddad, G.G.8
Karin, M.9
-
18
-
-
33645971047
-
Good cop, bad cop: The different faces of NFkappaB
-
Perkins ND, Gilmore TD. Good cop, bad cop: The different faces of NFkappaB. Cell Death Differ 2006; 13:759-72.
-
(2006)
Cell Death Differ
, vol.13
, pp. 759-772
-
-
Perkins, N.D.1
Gilmore, T.D.2
-
19
-
-
78149316509
-
Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection
-
Newton IP, Kenneth NS, Appleton PL, Nathke I, Rocha S. Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection. Mol Biol Cell 2010; 21:3630-8.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 3630-3638
-
-
Newton, I.P.1
Kenneth, N.S.2
Appleton, P.L.3
Nathke, I.4
Rocha, S.5
-
20
-
-
34547153223
-
Gene regulation under low oxygen: Holding your breath for transcription
-
DOI 10.1016/j.tibs.2007.06.005, PII S096800040700148X
-
Rocha S. Gene regulation under low oxygen: Holding your breath for transcription. Trends Biochem Sci 2007; 32:389-97. (Pubitemid 47126857)
-
(2007)
Trends in Biochemical Sciences
, vol.32
, Issue.8
, pp. 389-397
-
-
Rocha, S.1
-
21
-
-
0034682888
-
Asef, a link between the tumor suppressor APC and G-protein signaling
-
DOI 10.1126/science.289.5482.1194
-
Kawasaki Y, Senda T, Ishidate T, Koyama R, Morishita T, Iwayama Y, et al. Asef, a link between the tumor suppressor APC and G-protein signaling. Science 2000; 289:1194-7. (Pubitemid 30650732)
-
(2000)
Science
, vol.289
, Issue.5482
, pp. 1194-1197
-
-
Kawasaki, Y.1
Senda, T.2
Ishidate, T.3
Koyama, R.4
Morishita, T.5
Iwayama, Y.6
Higuchi, O.7
Akiyama, T.8
-
22
-
-
0037341566
-
Mutated APC and Asef are involved in the migration of colorectal tumour cells
-
DOI 10.1038/ncb937
-
Kawasaki Y, Sato R, Akiyama T. Mutated APC and Asef are involved in the migration of colorectal tumour cells. Nat Cell Biol 2003; 5:211-5. (Pubitemid 36322247)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.3
, pp. 211-215
-
-
Kawasaki, Y.1
Sato, R.2
Akiyama, T.3
-
23
-
-
20444490811
-
2-terminal fragments are the most stable part of the adenomatous polyposis coli protein and can be regulated by interactions with COOH-terminal domains
-
DOI 10.1158/0008-5472.CAN-04-4609
-
Li Z, Nathke IS. Tumor-associated NH2-terminal fragments are the most stable part of the adenomatous polyposis coli protein and can be regulated by interactions with COOH-terminal domains. Cancer Res 2005; 65:5195-204. (Pubitemid 40827329)
-
(2005)
Cancer Research
, vol.65
, Issue.12
, pp. 5195-5204
-
-
Li, Z.1
Nathke, I.S.2
-
24
-
-
46749094255
-
Novel self-association of the APC molecule affects APC clusters and cell migration
-
DOI 10.1242/jcs.029470
-
Li Z, Kroboth K, Newton IP, Nathke IS. Novel self-association of the APC molecule affects APC clusters and cell migration. J Cell Sci 2008; 121:1916-25. (Pubitemid 351943385)
-
(2008)
Journal of Cell Science
, vol.121
, Issue.11
, pp. 1916-1925
-
-
Li, Z.1
Kroboth, K.2
Newton, I.P.3
Nathke, I.S.4
-
25
-
-
65549159598
-
A two-step model for colon adenoma initiation and progression caused by APC loss
-
Phelps RA, Chidester S, Dehghanizadeh S, Phelps J, Sandoval IT, Rai K, et al. A two-step model for colon adenoma initiation and progression caused by APC loss. Cell 2009; 137:623-34.
-
(2009)
Cell
, vol.137
, pp. 623-634
-
-
Phelps, R.A.1
Chidester, S.2
Dehghanizadeh, S.3
Phelps, J.4
Sandoval, I.T.5
Rai, K.6
|